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Volumn 10, Issue 3, 2009, Pages 157-164

Helicobacter pylori infection, host genetics and gastric cancer

Author keywords

Chronic inflammation; Gastric cancer; Helicobacter pylori; Hostgenetics; Interleukins

Indexed keywords

INTERLEUKIN 1; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; MANNOSE BINDING LECTIN 2; PROSTATE STEM CELL ANTIGEN; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR ALPHA;

EID: 68149162278     PISSN: 17512972     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1751-2980.2009.00380.x     Document Type: Editorial
Times cited : (69)

References (48)
  • 1
    • 0000784774 scopus 로고
    • Schistosomes, Liver Flukes and Helicobacter pylori
    • International Agency for Research on Cancer monographs on the evaluation of carcinogenic risks to humans. Lyon, France: IARC
    • International Agency for Research on Cancer monographs on the evaluation of carcinogenic risks to humans. Schistosomes, Liver Flukes and Helicobacter pylori, Vol. 61. Lyon, France: IARC, 1994; 177-240.
    • (1994) Schistosomes, Liver Flukes and Helicobacter Pylori , vol.61 , pp. 177-240
  • 2
    • 37349009928 scopus 로고    scopus 로고
    • Host-bacterial interactions in Helicobacter pylori infection
    • Amieva MR, El-Omar EM. Host-bacterial interactions in Helicobacter pylori infection. Gastroenterology. 2008; 134: 306-23.
    • (2008) Gastroenterology , vol.134 , pp. 306-323
    • Amieva, M.R.1    El-Omar, E.M.2
  • 3
    • 4344718486 scopus 로고    scopus 로고
    • Challenge model for Helicobacter pylori infection in human volunteers
    • Graham DY, Opekun AR, Osato MS et al. Challenge model for Helicobacter pylori infection in human volunteers. Gut. 2004; 53: 1235-43.
    • (2004) Gut , vol.53 , pp. 1235-1243
    • Graham, D.Y.1    Opekun, A.R.2    Osato, M.S.3
  • 4
    • 0028900587 scopus 로고
    • The importance of local acid production in the distribution of Helicobacter felis in the mouse stomach
    • Danon SJ, O'Rourke JL, Moss ND, Lee A. The importance of local acid production in the distribution of Helicobacter felis in the mouse stomach. Gastroenterology. 1995; 108: 1386-95.
    • (1995) Gastroenterology , vol.108 , pp. 1386-1395
    • Danon, S.J.1    O'Rourke, J.L.2    Moss, N.D.3    Lee, A.4
  • 5
    • 15844369552 scopus 로고    scopus 로고
    • Atrophic gastritis and Helicobacter pylori infection in patients with reflux esophagitis treated with omeprazole or fundoplication
    • Kuipers EJ, Lundell L, Klinkenberg-Knol EC et al. Atrophic gastritis and Helicobacter pylori infection in patients with reflux esophagitis treated with omeprazole or fundoplication. N Engl J Med. 1996; 334: 1018-22.
    • (1996) N Engl J Med , vol.334 , pp. 1018-1022
    • Kuipers, E.J.1    Lundell, L.2    Klinkenberg-Knol, E.C.3
  • 6
    • 0035462919 scopus 로고    scopus 로고
    • Pathogenesis of Helicobacter pylori-induced gastric inflammation
    • Israel DA, Peek RM. pathogenesis of Helicobacter pylori-induced gastric inflammation. Aliment Pharmacol Ther. 2001; 15: 1271-90.
    • (2001) Aliment Pharmacol Ther , vol.15 , pp. 1271-1290
    • Israel, D.A.1    Peek, R.M.2
  • 7
    • 0026018806 scopus 로고
    • Interleukin-1 is cytoprotective, antisecretory, stimulates PGE2 synthesis by the stomach, and retards gastric emptying
    • Robert A, Olafsson AS, Lancaster C, Zhang WR. Interleukin-1 is cytoprotective, antisecretory, stimulates PGE2 synthesis by the stomach, and retards gastric emptying. Life Sci. 1991; 48: 123-34.
    • (1991) Life Sci , vol.48 , pp. 123-134
    • Robert, A.1    Olafsson, A.S.2    Lancaster, C.3    Zhang, W.R.4
  • 8
    • 0031922551 scopus 로고    scopus 로고
    • Interleukin 1 beta and tumour necrosis factor alpha inhibit acid secretion in cultured rabbit parietal cells by multiple pathways
    • Beales IL, Calam J. Interleukin 1 beta and tumour necrosis factor alpha inhibit acid secretion in cultured rabbit parietal cells by multiple pathways. Gut. 1998; 42: 227-34.
    • (1998) Gut , vol.42 , pp. 227-234
    • Beales, I.L.1    Calam, J.2
  • 9
    • 0030927818 scopus 로고    scopus 로고
    • Helicobacter pylori infection and chronic gastric acid hyposecretion
    • El-Omar EM, Oien K, El Nujumi A et al. Helicobacter pylori infection and chronic gastric acid hyposecretion. Gastroenterology. 1997; 113: 15-24.
    • (1997) Gastroenterology , vol.113 , pp. 15-24
    • El-Omar, E.M.1    Oien, K.2    El Nujumi, A.3
  • 10
    • 0029149571 scopus 로고
    • Helicobacter pylori infection and abnormalities of acid secretion in patients with duodenal ulcer disease
    • El-Omar EM, Penman ID, Ardill JE, Chittajallu RS, Howie C, McColl KE. Helicobacter pylori infection and abnormalities of acid secretion in patients with duodenal ulcer disease. Gastroenterology. 1995; 109: 681-91.
    • (1995) Gastroenterology , vol.109 , pp. 681-691
    • El-Omar, E.M.1    Penman, I.D.2    Ardill, J.E.3    Chittajallu, R.S.4    Howie, C.5    McColl, K.E.6
  • 11
    • 0012218357 scopus 로고    scopus 로고
    • Disease-specific Helicobacter pylori virulence factors: The unfulfilled promise
    • Graham DY, Yamaoka Y. Disease-specific Helicobacter pylori virulence factors: The unfulfilled promise. Helicobacter. 2000; 5(Suppl. 1): S3-S9.
    • (2000) Helicobacter , vol.5 , Issue.SUPPL. 1
    • Graham, D.Y.1    Yamaoka, Y.2
  • 12
    • 0029979369 scopus 로고    scopus 로고
    • Biologic basis for interleukin-1 in disease
    • Dinarello CA. Biologic basis for interleukin-1 in disease. Blood. 1996; 87: 2095-147.
    • (1996) Blood , vol.87 , pp. 2095-2147
    • Dinarello, C.A.1
  • 13
    • 0034744083 scopus 로고    scopus 로고
    • The importance of interleukin 1beta in Helicobacter pylori associated disease
    • El-Omar EM. The importance of interleukin 1beta in Helicobacter pylori associated disease. Gut. 2001; 48: 743-7.
    • (2001) Gut , vol.48 , pp. 743-747
    • El-Omar, E.M.1
  • 14
    • 0035319112 scopus 로고    scopus 로고
    • Cytokine gene polymorphism in human disease: On-line databases, supplement 1
    • Bidwell J, Keen L, Gallagher G et el. Cytokine gene polymorphism in human disease: On-line databases, supplement 1. Genes Immun. 2001; 2: 61-70.
    • (2001) Genes Immun , vol.2 , pp. 61-70
    • Bidwell, J.1    Keen, L.2    Gallagher, G.3
  • 15
    • 0034704880 scopus 로고    scopus 로고
    • Interleukin-1 polymorphisms associated with increased risk of gastric cancer
    • El-Omar EM, Carrington M, Chow WH et al. Interleukin-1 polymorphisms associated with increased risk of gastric cancer. Nature. 2000; 404: 398-402.
    • (2000) Nature , vol.404 , pp. 398-402
    • El-Omar, E.M.1    Carrington, M.2    Chow, W.H.3
  • 16
    • 0037622073 scopus 로고    scopus 로고
    • Increased risk of noncardia gastric cancer associated with proinflammatory cytokine gene polymorphisms
    • El-Omar EM, Rabkin CS, Gammon MD et al. Increased risk of noncardia gastric cancer associated with proinflammatory cytokine gene polymorphisms. Gastroenterology. 2003; 124: 1193-201.
    • (2003) Gastroenterology , vol.124 , pp. 1193-1201
    • El-Omar, E.M.1    Rabkin, C.S.2    Gammon, M.D.3
  • 17
    • 0034793044 scopus 로고    scopus 로고
    • Interleukin 1B and interleukin 1RN polymorphisms are associated with increased risk of gastric carcinoma
    • Machado JC, Pharoah P, Sousa S et al. Interleukin 1B and interleukin 1RN polymorphisms are associated with increased risk of gastric carcinoma. Gastroenterology. 2001; 121: 823-9.
    • (2001) Gastroenterology , vol.121 , pp. 823-829
    • Machado, J.C.1    Pharoah, P.2    Sousa, S.3
  • 18
    • 0037146297 scopus 로고    scopus 로고
    • Helicobacter pylori and interleukin 1 genotyping: An opportunity to identify high-risk individuals for gastric carcinoma
    • Figueiredo C, Machado JC, Pharoah P et al. Helicobacter pylori and interleukin 1 genotyping: An opportunity to identify high-risk individuals for gastric carcinoma. J Natl Cancer Inst. 2002; 94: 1680-7.
    • (2002) J Natl Cancer Inst , vol.94 , pp. 1680-1687
    • Figueiredo, C.1    Machado, J.C.2    Pharoah, P.3
  • 19
    • 0042667008 scopus 로고    scopus 로고
    • A proinflammatory genetic profile increases the risk for chronic atrophic gastritis and gastric carcinoma
    • Machado JC, Figueiredo C, Canedo P et al. A proinflammatory genetic profile increases the risk for chronic atrophic gastritis and gastric carcinoma. Gastroenterology. 2003; 125: 364-71.
    • (2003) Gastroenterology , vol.125 , pp. 364-371
    • Machado, J.C.1    Figueiredo, C.2    Canedo, P.3
  • 20
    • 0042315396 scopus 로고    scopus 로고
    • Synergistic effect of Helicobacter pylori virulence factors and interleukin-1 polymorphisms for the development of severe histological changes in the gastric mucosa
    • Rad R, Prinz C, Neu B et al. Synergistic effect of Helicobacter pylori virulence factors and interleukin-1 polymorphisms for the development of severe histological changes in the gastric mucosa. J Infect Dis. 2003; 188: 272-81.
    • (2003) J Infect Dis , vol.188 , pp. 272-281
    • Rad, R.1    Prinz, C.2    Neu, B.3
  • 21
    • 27744540489 scopus 로고    scopus 로고
    • Interleukin-1 gene polymorphisms and gastric cancer risk in a high-risk Italian population
    • Palli D, Saieva C, Luzzi I et al. Interleukin-1 gene polymorphisms and gastric cancer risk in a high-risk Italian population. Am J Gastroenterol. 2005; 100: 1941-8.
    • (2005) Am J Gastroenterol , vol.100 , pp. 1941-1948
    • Palli, D.1    Saieva, C.2    Luzzi, I.3
  • 22
    • 0035984024 scopus 로고    scopus 로고
    • Interleukin 1beta polymorphisms increase risk of hypochlorhydria and atrophic gastritis and reduce risk of duodenal ulcer recurrence in Japan
    • Furuta T, El-Omar EM, Xiao F, Shirai N, Takashima M, Sugimurra H. Interleukin 1beta polymorphisms increase risk of hypochlorhydria and atrophic gastritis and reduce risk of duodenal ulcer recurrence in Japan. Gastroenterology. 2002; 123: 92-105.
    • (2002) Gastroenterology , vol.123 , pp. 92-105
    • Furuta, T.1    El-Omar, E.M.2    Xiao, F.3    Shirai, N.4    Takashima, M.5    Sugimurra, H.6
  • 23
    • 0345528036 scopus 로고    scopus 로고
    • Association of interleukin 1B gene polymorphism and gastric cancers in high and low prevalence regions in China
    • Zeng ZR, Hu PJ, Hu S et al. Association of interleukin 1B gene polymorphism and gastric cancers in high and low prevalence regions in China. Gut. 2003; 52: 1684-9.
    • (2003) Gut , vol.52 , pp. 1684-1689
    • Zeng, Z.R.1    Hu, P.J.2    Hu, S.3
  • 24
    • 3042569219 scopus 로고    scopus 로고
    • Novel interleukin 1beta polymorphism increased the risk of gastric cancer in a Korean population
    • Lee KA, Ki CS, Kim HJ et al. Novel interleukin 1beta polymorphism increased the risk of gastric cancer in a Korean population. J Gastroenterol. 2004; 39: 429-33.
    • (2004) J Gastroenterol , vol.39 , pp. 429-433
    • Lee, K.A.1    Ki, C.S.2    Kim, H.J.3
  • 25
    • 20044378835 scopus 로고    scopus 로고
    • Interleukin-1B (IL-1B) polymorphisms and gastric mucosal levels of IL-1beta cytokine in Korean patients with gastric cancer
    • Chang YW, Jang JY, Kim NH et al. Interleukin-1B (IL-1B) polymorphisms and gastric mucosal levels of IL-1beta cytokine in Korean patients with gastric cancer. Int J Cancer. 2005; 114: 465-71.
    • (2005) Int J Cancer , vol.114 , pp. 465-471
    • Chang, Y.W.1    Jang, J.Y.2    Kim, N.H.3
  • 26
    • 5644262478 scopus 로고    scopus 로고
    • Interleukin-1B gene promoter variants are associated with an increased risk of gastric cancer in a Chinese population
    • Yang J, Hu Z, Xu Y et al. Interleukin-1B gene promoter variants are associated with an increased risk of gastric cancer in a Chinese population. Cancer Lett. 2004; 215: 191-8.
    • (2004) Cancer Lett , vol.215 , pp. 191-198
    • Yang, J.1    Hu, Z.2    Xu, Y.3
  • 27
    • 32144455365 scopus 로고    scopus 로고
    • Single nucleotide polymorphisms in the human interleukin-1B gene affect transcription according to haplotype context
    • Chen HM, Wilkins LM, Aziz N et al. Single nucleotide polymorphisms in the human interleukin-1B gene affect transcription according to haplotype context. Hum Mol Genet. 2006; 15: 519-29.
    • (2006) Hum Mol Genet , vol.15 , pp. 519-529
    • Chen, H.M.1    Wilkins, L.M.2    Aziz, N.3
  • 28
    • 34447534253 scopus 로고    scopus 로고
    • Interaction of polymorphisms in the interleukin 1B-31 and general transcription factor 2A1 genes on the susceptibility to gastric cancer
    • Lee KA, Park JH, Sohn TS, Kim S, Rhee JC, Kim JW. Interaction of polymorphisms in the interleukin 1B-31 and general transcription factor 2A1 genes on the susceptibility to gastric cancer. Cytokine. 2007; 38: 96-100.
    • (2007) Cytokine , vol.38 , pp. 96-100
    • Lee, K.A.1    Park, J.H.2    Sohn, T.S.3    Kim, S.4    Rhee, J.C.5    Kim, J.W.6
  • 29
    • 34548057795 scopus 로고    scopus 로고
    • Interleukin1beta genetic polymorphisms interact with polyunsaturated fatty acids to modulate risk of the metabolic syndrome
    • Shen J, Arnett DK, Peacock JM et al. Interleukin1beta genetic polymorphisms interact with polyunsaturated fatty acids to modulate risk of the metabolic syndrome. J Nutr. 2007; 137: 1846-51.
    • (2007) J Nutr , vol.137 , pp. 1846-18451
    • Shen, J.1    Arnett, D.K.2    Peacock, J.M.3
  • 30
    • 54549089856 scopus 로고    scopus 로고
    • Overexpression of interleukin-1[beta]induces gastric inflammation and cancer and mobilizes myeloid-derived suppressor cells in mice
    • Tu S, Bhagat G, Cui G et al. Overexpression of interleukin-1[beta]induces gastric inflammation and cancer and mobilizes myeloid-derived suppressor cells in mice. Cancer Cell. 2008; 14: 408-19.
    • (2008) Cancer Cell , vol.14 , pp. 408-419
    • Tu, S.1    Bhagat, G.2    Cui, G.3
  • 31
    • 68949114416 scopus 로고    scopus 로고
    • T-bet knockout prevents Helicobacter felis induced gastric cancer
    • Stoicov C, Fan X, Liu JH et al. T-bet knockout prevents Helicobacter felis induced gastric cancer. J Immunol. 2009.
    • (2009) J Immunol
    • Stoicov, C.1    Fan, X.2    Liu, J.H.3
  • 32
    • 53349171324 scopus 로고    scopus 로고
    • Tumor necrosis factor alpha extended haplotypes and risk of gastric carcinoma
    • Canedo P, Duraes C, Pereira F et al. Tumor necrosis factor alpha extended haplotypes and risk of gastric carcinoma. Cancer Epidemiol Biomarkers Prev. 2008; 17: 2416-20.
    • (2008) Cancer Epidemiol Biomarkers Prev , vol.17 , pp. 2416-2420
    • Canedo, P.1    Duraes, C.2    Pereira, F.3
  • 33
    • 30044451653 scopus 로고    scopus 로고
    • The IL-8-251 promoter polymorphism is associated with high IL-8 production, severe inflammation and increased risk of pre-malignant changes in H-pylori positive subjects
    • Smith MG, Hold GL, Rabkin CS et al. The IL-8-251 promoter polymorphism is associated with high IL-8 production, severe inflammation and increased risk of pre-malignant changes in H-pylori positive subjects. Gastroenterology. 2004; 126(4 Suppl 2): A23.
    • (2004) Gastroenterology , vol.126 , Issue.4 SUPPL. 2
    • Smith, M.G.1    Hold, G.L.2    Rabkin, C.S.3
  • 34
    • 28644442435 scopus 로고    scopus 로고
    • Interleukin-8 promoter polymorphism increases the risk of atrophic gastritis and gastric cancer in Japan
    • Taguchi A, Ohmiya N, Shirai K et al. Interleukin-8 promoter polymorphism increases the risk of atrophic gastritis and gastric cancer in Japan. Cancer Epidemiol Biomarkers Prev. 2005; 14: 2487-93.
    • (2005) Cancer Epidemiol Biomarkers Prev , vol.14 , pp. 2487-2493
    • Taguchi, A.1    Ohmiya, N.2    Shirai, K.3
  • 35
    • 16244383220 scopus 로고    scopus 로고
    • Genetic polymorphisms of interleukin (IL)-1B, IL-1RN, IL-8, IL-10 and tumor necrosis factor (alpha) and risk of gastric cancer in a Chinese population
    • Lu W, Pan K, Zhang L, Lin D, Miao X, You W. Genetic polymorphisms of interleukin (IL)-1B, IL-1RN, IL-8, IL-10 and tumor necrosis factor (alpha) and risk of gastric cancer in a Chinese population. Carcinogenesis. 2005; 26: 631-6.
    • (2005) Carcinogenesis , vol.26 , pp. 631-636
    • Lu, W.1    Pan, K.2    Zhang, L.3    Lin, D.4    Miao, X.5    You, W.6
  • 36
    • 25144473975 scopus 로고    scopus 로고
    • The -251T allele of the interleukin-8 promoter is associated with increased risk of gastric carcinoma featuring diffuse-type histopathology in Chinese population
    • Lee WP, Tai DI, Lan KH et al. The -251T allele of the interleukin-8 promoter is associated with increased risk of gastric carcinoma featuring diffuse-type histopathology in Chinese population. Clin Cancer Res. 2005; 11: 6431-41.
    • (2005) Clin Cancer Res , vol.11 , pp. 6431-6441
    • Lee, W.P.1    Tai, D.I.2    Lan, K.H.3
  • 37
    • 20044386655 scopus 로고    scopus 로고
    • The polymorphism interleukin 8-251 A/T influences the susceptibility of Helicobacter pylori related gastric diseases in the Japanese population
    • Ohyauchi M, Imatani A, Yonechi M et al. The polymorphism interleukin 8-251 A/T influences the susceptibility of Helicobacter pylori related gastric diseases in the Japanese population. Gut. 2005; 54: 330-5.
    • (2005) Gut , vol.54 , pp. 330-335
    • Ohyauchi, M.1    Imatani, A.2    Yonechi, M.3
  • 38
    • 33748702112 scopus 로고    scopus 로고
    • The interleukin-8-251 promoter polymorphism and risk of gastric cancer in Caucasian and Japanese populations
    • Smith MG, Hold GL, Rabkin CS et al. The interleukin-8-251 promoter polymorphism and risk of gastric cancer in Caucasian and Japanese populations. Gastroenterology. 2005; 128(4 Suppl 2): A19.
    • (2005) Gastroenterology , vol.128 , Issue.4 SUPPL. 2
    • Smith, M.G.1    Hold, G.L.2    Rabkin, C.S.3
  • 39
    • 33845682589 scopus 로고    scopus 로고
    • Polymorphisms in Th1-type cell-mediated response genes and risk of gastric cancer
    • Hou L, El Omar EM, Chen J et al. Polymorphisms in Th1-type cell-mediated response genes and risk of gastric cancer. Carcinogenesis. 2007; 28: 118-23.
    • (2007) Carcinogenesis , vol.28 , pp. 118-123
    • Hou, L.1    El Omar, E.M.2    Chen, J.3
  • 40
    • 54349104757 scopus 로고    scopus 로고
    • The interferon gamma receptor 1 (IFNGR1) -56C/T gene polymorphism is associated with increased risk of early gastric carcinoma
    • Canedo P, Corso G, Pereira F et al. The interferon gamma receptor 1 (IFNGR1) -56C/T gene polymorphism is associated with increased risk of early gastric carcinoma. Gut. 2008; 57: 1504-8.
    • (2008) Gut , vol.57 , pp. 1504-1508
    • Canedo, P.1    Corso, G.2    Pereira, F.3
  • 41
    • 52449120937 scopus 로고    scopus 로고
    • Genetic variants in T helper cell type 1, 2 and 3 pathways and gastric cancer risk in a Polish population
    • Mahajan R, El-Omar EM, Lissowska J et al. Genetic variants in T helper cell type 1, 2 and 3 pathways and gastric cancer risk in a Polish population. Jpn J Clin Oncol. 2008; 38: 626-33.
    • (2008) Jpn J Clin Oncol , vol.38 , pp. 626-633
    • Mahajan, R.1    El-Omar, E.M.2    Lissowska, J.3
  • 43
    • 0038781687 scopus 로고    scopus 로고
    • Helicobacter pylori activates Toll-like receptor 4 expression in gastrointestinal epithelial cells
    • Su B, Ceponis PJ, Lebel S, Huynh H, Sherman PM. Helicobacter pylori activates Toll-like receptor 4 expression in gastrointestinal epithelial cells. Infect Immun. 2003; 71: 3496-502.
    • (2003) Infect Immun , vol.71 , pp. 3496-3502
    • Su, B.1    Ceponis, P.J.2    Lebel, S.3    Huynh, H.4    Sherman, P.M.5
  • 44
    • 33947304959 scopus 로고    scopus 로고
    • A functional polymorphism of toll-like receptor 4 gene increases risk of gastric carcinoma and its precursors
    • Hold GL, Rabkin CS, Chow WH et al. A functional polymorphism of toll-like receptor 4 gene increases risk of gastric carcinoma and its precursors. Gastroenterology. 2007; 132: 905-12.
    • (2007) Gastroenterology , vol.132 , pp. 905-912
    • Hold, G.L.1    Rabkin, C.S.2    Chow, W.H.3
  • 45
    • 55449103507 scopus 로고    scopus 로고
    • Toll-like receptor 4 Asp299Gly and Thr399Ile polymorphisms in gastric cancer of intestinal and diffuse histotypes
    • Santini D, Angeletti S, Ruzzo A et al. Toll-like receptor 4 Asp299Gly and Thr399Ile polymorphisms in gastric cancer of intestinal and diffuse histotypes. Clin Exp Immunol. 2008; 154: 360-4.
    • (2008) Clin Exp Immunol , vol.154 , pp. 360-364
    • Santini, D.1    Angeletti, S.2    Ruzzo, A.3
  • 46
    • 33748511445 scopus 로고    scopus 로고
    • Mannose-binding lectin-2 genetic variation and stomach cancer risk
    • Baccarelli A, Hou L, Chen J et al. Mannose-binding lectin-2 genetic variation and stomach cancer risk. Int J Cancer. 2006; 119: 1970-5.
    • (2006) Int J Cancer , vol.119 , pp. 1970-1975
    • Baccarelli, A.1    Hou, L.2    Chen, J.3
  • 47
    • 44349178008 scopus 로고    scopus 로고
    • Genetic variation in PSCA is associated with susceptibility to diffuse-type gastric cancer
    • Sakamoto H, Yoshimura K, Saeki N et al. Genetic variation in PSCA is associated with susceptibility to diffuse-type gastric cancer. Nat Genet. 2008; 40: 730-40.
    • (2008) Nat Genet , vol.40 , pp. 730-740
    • Sakamoto, H.1    Yoshimura, K.2    Saeki, N.3
  • 48
    • 38949199463 scopus 로고    scopus 로고
    • Transgenic expression of Helicobacter pylori CagA induces gastrointestinal and hematopoietic neoplasms in mouse
    • Ohnishi N, Yuasa H, Tanaka S et al. Transgenic expression of Helicobacter pylori CagA induces gastrointestinal and hematopoietic neoplasms in mouse. Proc Natl Acad Sci USA. 2008; 105: 1003-8.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 1003-1008
    • Ohnishi, N.1    Yuasa, H.2    Tanaka, S.3


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