Conserved glycine at position 45 of major cochlear connexins constitutes a vital component of the Ca2+ sensor for gating of gap junction hemichannels

Biochemical and Biophysical Research Communications

Volumn 436, Issue 3, 2013, Pages 424-429

  Zhang, Yanping ^a   Hao, Hongxia ^a  

^a 309TH HOSPITAL OF PLA   (China)

Author keywords

Calcium; Connexin 26; Gap junctions; GJB6 protein human; Ion channel gating

Indexed keywords

CALCIUM ION; CONNEXIN 26; CONNEXIN 30; CONNEXIN 32; CONNEXIN 43; GAP JUNCTION PROTEIN; GLYCINE; NEURONAL CALCIUM SENSOR;

ARTICLE; CELL DEATH; CELL STRAIN HEK293; COCHLEA; GAIN OF FUNCTION MUTATION; GAP JUNCTION; HUMAN; HUMAN CELL; IN VITRO STUDY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; WILD TYPE;

CALCIUM; CONNEXIN 26; GAP JUNCTIONS; GJB6 PROTEIN HUMAN; ION CHANNEL GATING;

AMINO ACID SUBSTITUTION; CALCIUM; CALCIUM CHANNELS; CELL DEATH; CELL MEMBRANE; CELL MEMBRANE PERMEABILITY; COCHLEA; CONNEXIN 43; CONNEXINS; DEAFNESS; DOSE-RESPONSE RELATIONSHIP, DRUG; GAP JUNCTIONS; GLUTAMIC ACID; GLYCINE; HEK293 CELLS; HUMANS; ICHTHYOSIS; KERATITIS; MUTAGENESIS, SITE-DIRECTED; TRANSFECTION;

EID: 84879885206     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2013.05.118     Document Type: Article

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