PKA negatively regulates PP2Cβ to activate NF-κB-mediated inflammatory signaling

Biochemical and Biophysical Research Communications

Volumn 436, Issue 3, 2013, Pages 473-477

  Choi, Hyo Kyung ^a   Park, Soo Yeon ^a   Oh, Hye Jeong ^a   Han, Eun Jeong ^a   Lee, Yoo Hyun ^b   Lee, Jeongmin ^c   Jun, Woo Jin ^d   Choi, Kyung Chul ^e   Yoon, Ho Geun ^a  

^a Yonsei University College of Medicine   (South Korea)

^b Suwon University   (South Korea)

^c Kyung Hee University   (South Korea)

^d Chonnam National University   (South Korea)

^e University of Ulsan   (South Korea)

Author keywords

Cytokines; Inflammation; NF B; Protein kinase A; Protein phosphatase 2C ; Ubiquitin dependent proteasomal degradation

Indexed keywords

BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; CYCLIC AMP DEPENDENT PROTEIN KINASE; FORSKOLIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; N [2 (4 BROMOCINNAMYLAMINO)ETHYL] 5 ISOQUINOLINESULFONAMIDE; PHOSPHOPROTEIN PHOSPHATASE; PHOSPHOPROTEIN PHOSPHATASE 2C BETA; SERINE; UBIQUITIN; UNCLASSIFIED DRUG;

ANTIINFLAMMATORY ACTIVITY; ARTICLE; HUMAN; HUMAN CELL; IN VITRO STUDY; INFLAMMATION; MUTATION; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DEPHOSPHORYLATION; PROTEIN PHOSPHORYLATION; REGULATORY MECHANISM; SEQUENCE ANALYSIS; SIGNAL TRANSDUCTION; UBIQUITINATION; WESTERN BLOTTING;

CYTOKINES; INFLAMMATION; NF-ΚB; PROTEIN KINASE A; PROTEIN PHOSPHATASE 2CΒ; UBIQUITIN-DEPENDENT PROTEASOMAL DEGRADATION;

CYCLIC AMP-DEPENDENT PROTEIN KINASES; ENZYME STABILITY; FORSKOLIN; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HEK293 CELLS; HUMANS; INFLAMMATION; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; ISOQUINOLINES; NF-KAPPA B; PHOSPHOPROTEIN PHOSPHATASES; PHOSPHORYLATION; PROTEOLYSIS; SERINE; SIGNAL TRANSDUCTION; SULFONAMIDES; TUMOR NECROSIS FACTOR-ALPHA; UBIQUITIN;

EID: 84879882622     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2013.05.129     Document Type: Article

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