Generation of mouse models for type 1 diabetes by selective depletion of pancreatic beta cells using toxin receptor-mediated cell knockout

Biochemical and Biophysical Research Communications

Volumn 436, Issue 3, 2013, Pages 400-405

  Matsuoka, Kunie ^a,d   Saito, Michiko ^b,d   Shibata, Kosuke ^a   Sekine, Michiko ^a   Shitara, Hiroshi ^a   Taya, Choji ^a   Zhang, Xiaohong ^c   Takahashi, Tsuneo A ^c   Kohno, Kenji ^b,d   Kikkawa, Yoshiaki ^a   Yonekawa, Hiromichi ^a,d  

^a TOKYO METROPOLITAN INSTITUTE OF MEDICAL SCIENCE   (Japan)

^b NARA INSTITUTE OF SCIENCE AND TECHNOLOGY   (Japan)

^c UNIVERSITY OF TOKYO   (Japan)

^d NARO Bio oriented Technology Research Advancement Institution   (Japan)

Author keywords

Allogeneic transplantation; Diabetes; Diphtheria toxin; Transgenic mice; Xenogeneic transplantation

Indexed keywords

DIPHTHERIA TOXIN; INSULIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; HUMAN; HUMAN CELL; HYPERGLYCEMIA; IMMUNOHISTOLOGY; INSULIN BLOOD LEVEL; INSULIN DEPENDENT DIABETES MELLITUS; MOUSE; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROMOTER REGION; TRANSGENIC MOUSE; UMBILICAL CORD BLOOD; XENOGRAFT;

ALLOGENEIC TRANSPLANTATION; DIABETES; DIPHTHERIA TOXIN; TRANSGENIC MICE; XENOGENEIC TRANSPLANTATION;

ANIMALS; ANTIGENS, CD34; CORD BLOOD STEM CELL TRANSPLANTATION; DIABETES MELLITUS, EXPERIMENTAL; DIABETES MELLITUS, TYPE 1; DIPHTHERIA TOXIN; GENE KNOCKOUT TECHNIQUES; GLUCOSE; HUMANS; HYPERGLYCEMIA; INSULIN-SECRETING CELLS; INSULINS; MICE; MICE, INBRED C57BL; MICE, SCID; MICE, TRANSGENIC; RECEPTORS, CELL SURFACE; TRANSPLANTATION, HETEROLOGOUS; TRANSPLANTATION, HOMOLOGOUS;

MURINAE; MUS; MUS MUSCULUS;

EID: 84879880873     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2013.05.114     Document Type: Article

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