Autoantibodies to posttranslationally modified type II collagen as potential biomarkers for rheumatoid arthritis

Arthritis and Rheumatism

Volumn 65, Issue 7, 2013, Pages 1702-1712

  Strollo, Rocky ^a,b   Ponchel, Frederique ^c,d   Malmström, Vivianne ^e   Rizzo, Paola ^a,f   Bombardieri, Michele ^a   Wenham, Claire Y ^c,d   Landy, Rebecca ^a   Perret, David ^a   Watt, Fiona ^g,h   Corrigall, Valerie M ⁱ   Winyard, Paul G ^j   Pozzilli, Paolo ^a,b   Conaghan, Philip G ^c,d   Panayi, Gabriel S ⁱ   Klareskog, Lars ^e   Emery, Paul ^c,d   Nissim, Ahuva ^a  

^a QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

^b UNIVERSITY CAMPUS BIO MEDICO   (Italy)

^c UNIVERSITY OF LEEDS   (United Kingdom)

^d LEEDS TEACHING HOSPITALS NHS TRUST   (United Kingdom)

^e KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^f CATHOLIC UNIVERSITY   (Italy)

^g UNIVERSITY OF OXFORD   (United Kingdom)

^h UNIVERSITY OF OXFORD   (United Kingdom)

ⁱ KING'S COLLEGE LONDON   (United Kingdom)

^j UNIVERSITY OF EXETER MEDICAL SCHOOL   (United Kingdom)

more..

Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIBODY; COLLAGEN TYPE 2; DISEASE MODIFYING ANTIRHEUMATIC DRUG; OXIDIZING AGENT; REACTIVE OXYGEN METABOLITE;

ADULT; AGED; ARTHRALGIA; ARTICLE; BLOOD SAMPLING; CHRONIC DISEASE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMAN; LONGITUDINAL STUDY; MAJOR CLINICAL STUDY; MALE; OSTEOARTHRITIS; PRIORITY JOURNAL; PROTEIN PROCESSING; RHEUMATOID ARTHRITIS; SENSITIVITY AND SPECIFICITY; SYNOVIAL FLUID;

ADULT; AGED; AGED, 80 AND OVER; ANTIRHEUMATIC AGENTS; ARTHRITIS, RHEUMATOID; AUTOANTIBODIES; BIOLOGICAL MARKERS; CASE-CONTROL STUDIES; COLLAGEN TYPE II; DISEASE PROGRESSION; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMANS; MALE; MIDDLE AGED; OSTEOARTHRITIS; PEPTIDES, CYCLIC; PHOSPHOPROTEINS; PROTEIN PROCESSING, POST-TRANSLATIONAL; SEVERITY OF ILLNESS INDEX; SYNOVIAL FLUID; YOUNG ADULT;

EID: 84879848482     PISSN: 00043591     EISSN: 15290131     Source Type: Journal    
DOI: 10.1002/art.37964     Document Type: Article

References (45)

1. McInnes IB, O'Dell JR,. State-of-the-art: rheumatoid arthritis [review]. Ann Rheum Dis 2010; 69: 1898-906.
2. Gilston V, Blake DR, Winyard PG,. Inflammatory mediators, free radicals and gene transcription. In:, Winyard PG, Blake DR, Evans CH, editors. Free radicals and inflammation. Boston: Birkhauser Verlag; 2000. p. 83-98.
3. Murphy G, Nagase H,. Reappraising metalloproteinases in rheumatoid arthritis and osteoarthritis: destruction or repair? Nat Clin Pract Rheumatol 2008; 4: 128-35.
4. Winyard PG, Moody CJ, Jacob C,. Oxidative activation of antioxidant defence. Trends Biochem Sci 2005; 30: 453-61.
5. Winyard PG, Ryan B, Eggleton P, Nissim A, Taylor E, Lo Faro ML, et al. Measurement and meaning of markers of reactive species of oxygen, nitrogen and sulfur in healthy human subjects and patients with inflammatory joint disease. Biochem Soc Trans 2011; 39: 1226-32.
6. Bailey AJ, Sims TJ, Avery NC, Halligan EP,. Non-enyzmic glycation of fibrous collagen: reaction products of glucose and ribose. Biochem J 1995; 305: 385-90.
7. Dobritzsch D, Lindh I, Uysal H, Nandakumar KS, Burkhardt H, Schneider G, et al. Crystal structure of an arthritogenic anticollagen immune complex. Arthritis Rheum 2011; 63: 3740-8.
8. Holmdahl R, Bockermann R, Backlund J, Yamada H,. The molecular pathogenesis of collagen-induced arthritis in mice: a model for rheumatoid arthritis. Ageing Res Rev 2002; 1: 135-47.
9. Nissim A, Winyard PG, Corrigall V, Fatah R, Perrett D, Panayi G, et al. Generation of neoantigenic epitopes after posttranslational modification of type II collagen by factors present within the inflamed joint. Arthritis Rheum 2005; 52: 3829-38.
10. Pruijn GJ, Wiik A, van Venrooij WJ,. The use of citrullinated peptides and proteins for the diagnosis of rheumatoid arthritis. Arthritis Res Ther 2010; 12: 203.
11. Burkhardt H, Sehnert B, Bockermann R, Engstrom A, Kalden JR, Holmdahl R,. Humoral immune response to citrullinated collagen type II determinants in early rheumatoid arthritis. Eur J Immunol 2005; 35: 1643-52.
12. Snir O, Widhe M, Hermansson M, von Spee C, Lindberg J, Hensen S, et al. Antibodies to several citrullinated antigens are enriched in the joints of rheumatoid arthritis patients. Arthritis Rheum 2010; 62: 44-52.
13. Snir O, Widhe M, von Spee C, Lindberg J, Padyukov L, Lundberg K, et al. Multiple antibody reactivities to citrullinated antigens in sera from patients with rheumatoid arthritis: association with HLA-DRB1 alleles. Ann Rheum Dis 2009; 68: 736-43.
14. Avouac J, Gossec L, Dougados M,. Diagnostic and predictive value of anti-cyclic citrullinated protein antibodies in rheumatoid arthritis: a systematic literature review. Ann Rheum Dis 2006; 65: 845-51.
15. Goeb V, Dieude P, Daveau R, Thomas-L'otellier M, Jouen F, Hau F, et al. Contribution of PTPN22 1858T, TNFRII 196R and HLA-shared epitope alleles with rheumatoid factor and anti-citrullinated protein antibodies to very early rheumatoid arthritis diagnosis. Rheumatology (Oxford) 2008; 47: 1208-12.
16. Schellekens GA, de Jong BA, van den Hoogen FH, van de Putte LB, van Venrooij WJ,. Citrulline is an essential constituent of antigenic determinants recognized by rheumatoid arthritis-specific autoantibodies. J Clinical Invest 1998; 101: 273-81.
17. Lindstrom TM, Robinson WH,. Biomarkers for rheumatoid arthritis: making it personal. Scand J Clin Lab Invest Suppl 2010; 242: 79-84.
18. Arnett FC, Edworthy SM, Bloch DA, McShane DJ, Fries JF, Cooper NS, et al. The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum 1988; 31: 315-24.
19. Prevoo ML, van 't Hof MA, Kuper HH, van Leeuwen MA, van de Putte LB, van Riel PL,. Modified disease activity scores that include twenty-eight-joint counts: development and validation in a prospective longitudinal study of patients with rheumatoid arthritis. Arthritis Rheum 1995; 38: 44-8.
20. Altman R, Asch E, Bloch D, Bole G, Borenstein D, Brandt K, et al. Development of criteria for the classification and reporting of osteoarthritis: classification of osteoarthritis of the knee. Arthritis Rheum 1986; 29: 1039-49.
21. Cuzick J,. A Wilcoxon-type test for trend. Stat Med 1985; 4: 87-90.
22. Deane KD, O'Donnell CI, Hueber W, Majka DS, Lazar AA, Derber LA, et al. The number of elevated cytokines and chemokines in preclinical seropositive rheumatoid arthritis predicts time to diagnosis in an age-dependent manner. Arthritis Rheum 2010; 62: 3161-72.
23. Van Venrooij WJ, van Beers JJ, Pruijn GJ,. Anti-CCP antibody, a marker for the early detection of rheumatoid arthritis. Ann N Y Acad Sci 2008; 1143: 268-85.
24. Goeb V, Aegerter P, Parmar R, Fardellone P, Vittecoq O, Conaghan PG, et al. Progression to rheumatoid arthritis in early inflammatory arthritis is associated with low IL-7 serum levels. Ann Rheum Dis 2013; 72: 1032-6.
25. Gonzalez-Alvaro I, Ortiz AM, Alvaro-Gracia JM, Castaneda S, Diaz-Sanchez B, Carvajal I, et al. Interleukin 15 levels in serum may predict a severe disease course in patients with early arthritis. PLoS One 2011; 6: e29492.
26. Kolarz B, Majdan M, Dryglewska M, Darmochwal-Kolarz D,. Antibodies against cyclic citrullinated peptide don't decrease after 6 months of infliximab treatment in refractory rheumatoid arthritis. Rheumatol Int 2011; 31: 1439-43.
27. Ronnelid J, Wick MC, Lampa J, Lindblad S, Nordmark B, Klareskog L, et al. Longitudinal analysis of citrullinated protein/peptide antibodies (anti-CP) during 5 year follow up in early rheumatoid arthritis: anti-CP status predicts worse disease activity and greater radiological progression. Ann Rheum Dis 2005; 64: 1744-9.
28. Teng YO, Wheater G, Hogan VE, Stocks P, Levarht EN, Huizinga TW, et al. Induction of long-term B-cell depletion in refractory rheumatoid arthritis patients preferentially affects autoreactive more than protective humoral immunity. Arthritis Res Ther 2012; 14: R57.
29. Andriopoulos NA, Mestecky J, Miller EJ, Bradley EL,. Antibodies to native and denatured collagens in sera of patients with rheumatoid arthritis. Arthritis Rheum 1976; 19: 613-7.
30. Kim WU, Cho ML, Jung YO, Min SY, Park SW, Min DJ, et al. Type II collagen autoimmunity in rheumatoid arthritis. Am J Med Sci 2004; 327: 202-11.
31. Kim WU, Yoo WH, Park W, Kang YM, Kim SI, Park JH, et al. IgG antibodies to type II collagen reflect inflammatory activity in patients with rheumatoid arthritis. J Rheumatol 2000; 3: 575-81.
32. Terato K, DeArmey DA, Ye XJ, Griffiths MM, Cremer MA,. The mechanism of autoantibody formation to cartilage in rheumatoid arthritis: possible cross-reaction of antibodies to dietary collagens with autologous type II collagen. Clin Immunol Immunopathol 1996; 79: 142-54.
33. Rantapaa-Dahlqvist S, de Jong BA, Berglin E, Hallmans G, Wadell G, Stenlund H, et al. Antibodies against cyclic citrullinated peptide and IgA rheumatoid factor predict the development of rheumatoid arthritis. Arthritis Rheum 2003; 48: 2741-9.
34. Van de Stadt LA, de Koning MH, van de Stadt RJ, Wolbink G, Dijkmans BA, Hamann D, et al. Development of the anti-citrullinated protein antibody repertoire prior to the onset of rheumatoid arthritis. Arthritis Rheum 2011; 63: 3226-33.
35. Sellam J, Berenbaum F,. The role of synovitis in pathophysiology and clinical symptoms of osteoarthritis. Nat Rev Rheumatol 2010; 6: 625-35.
36. Loeser RF,. Aging and osteoarthritis: the role of chondrocyte senescence and aging changes in the cartilage matrix. Osteoarthritis Cartilage 2009; 17: 971-9.
37. Willett TL, Kandel R, De Croos JN, Avery NC, Grynpas MD,. Enhanced levels of non-enzymatic glycation and pentosidine crosslinking in spontaneous osteoarthritis progression. Osteoarthritis Cartilage 2012; 20: 736-44.
38. Hendler A, Mulli TK, Hughes FJ, Perrett D, Bombardieri M, Houri-Haddad Y, et al. Involvement of autoimmunity in the pathogenesis of aggressive periodontitis. J Dent Res 2010; 89: 1389-94.
39. Rosenthal M, Stastny P, Ziff M,. Enhancement of immunoglobulin and rheumatoid factor synthesis by rheumatoid synovial effusions and synovial membrane culture supernatants. Rheumatology 1975; 6: 87-9.
40. Humby F, Bombardieri M, Manzo A, Kelly S, Blades MC, Kirkham B, et al. Ectopic lymphoid structures support ongoing production of class-switched autoantibodies in rheumatoid synovium. PLoS Med 2009; 6: e1.
41. Hughes C, Faurholm B, Dell'Accio F, Manzo A, Seed M, Eltawil N, et al. Human single-chain variable fragment that specifically targets arthritic cartilage. Arthritis Rheum 2010; 62: 1007-16.
42. Mullazehi M, Wick MC, Klareskog L, van Vollenhoven R, Ronnelid J,. Anti-type II collagen antibodies are associated with early radiographic destruction in rheumatoid arthritis. Arthritis Research Ther 2012; 14: R100.
43. Strollo R, Rizzo P, Spoletini M, Landy R, Hughes C, Ponchel F, et al. HLA-dependent autoantibodies against post-translationally modified collagen type II in type 1 diabetes mellitus. Diabetologia 2013; 56: 563-72.
44. Stamp LK, Khalilova I, Tarr JM, Senthilmohan R, Turner R, Haigh RC, et al. Myeloperoxidase and oxidative stress in rheumatoid arthritis. Rheumatology (Oxford) 2012; 51: 1796-803.
45. Requena JR, Price DL, Thorpe SR, Baynes JW,. Measurement of pentosidine in biological samples. Methods Mol Med 2000; 38: 209-17.