Potential bias in medication adherence studies of prevalent users

Health Services Research

Volumn 48, Issue 4, 2013, Pages 1468-1486

  Maciejewski, Matthew L ^a   Bryson, Chris L ^b   Wang, Virginia ^a   Perkins, Mark ^b   Liu, Chuan Fen ^b  

^a DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF WASHINGTON   (United States)

Author keywords

cost sharing; inclusion criteria; Medication adherence; pharmaceutical policy; research design; veterans

Indexed keywords

ORAL ANTIDIABETIC AGENT;

ADULT; AGED; ARTICLE; COHORT ANALYSIS; CONTROLLED STUDY; DIABETES MELLITUS; DIABETIC PATIENT; DRUG COST; DRUG MONITORING; DRUG USE; FEMALE; HEALTH CARE POLICY; HUMAN; MAJOR CLINICAL STUDY; MALE; MEDICAL HISTORY; MULTICENTER STUDY; OUTCOME ASSESSMENT; PATIENT COMPLIANCE; PHARMACY; PREVALENCE; RETROSPECTIVE STUDY; TREND STUDY;

COST SHARING; INCLUSION CRITERIA; MEDICATION ADHERENCE; PHARMACEUTICAL POLICY; RESEARCH DESIGN; VETERANS;

AGED; AGED, 80 AND OVER; BIAS (EPIDEMIOLOGY); DEDUCTIBLES AND COINSURANCE; DRUG COSTS; FEMALE; HEALTH SERVICES RESEARCH; HUMANS; MALE; MEDICATION ADHERENCE; MIDDLE AGED; PRESCRIPTION DRUGS; TIME FACTORS;

EID: 84879843877     PISSN: 00179124     EISSN: 14756773     Source Type: Journal    
DOI: 10.1111/1475-6773.12043     Document Type: Article

References (25)

1. Blais, L., J. Couture, E. Rahme, and, J. LeLorier,. 2003. " Impact of a Cost Sharing Drug Insurance Plan on Drug Utilization among Individuals Receiving Social Assistance." Health Policy 64 (2): 163-72.
2. Bryson, C. L., D. H. Au, B. Young, M. B. McDonell, and, S. D. Fihn,. 2007. " A Refill Adherence Algorithm for Multiple Short Intervals to Estimate Refill Compliance." Medical Care 45: 497-504.
3. Concato, J., E. V. Lawler, R. A. Lew, J. M. Gaziano, M. Aslan, and, G. D. Huang,. 2010. " Observational Methods in Comparative Effectiveness Research." American Journal of Medicine 123 (12 suppl 1): e16-23.
4. Danaei, G., M. Tavakkoli, and, M. A. Hernan,. 2012. " Bias in Observational Studies of Prevalent Users: Lessons for Comparative Effectiveness Research from a Meta-Analysis of Statins." American Journal of Epidemiology 175 (4): 250-62.
5. Doshi, J. A., J. Zhu, B. Y. Lee, S. E. Kimmel, and, K. G. Volpp,. 2009. " Impact of a Prescription Copayment Increase on Lipid-Lowering Medication Adherence in Veterans." Circulation 119 (3): 390-7.
6. Fan, V. S., M. L. Maciejewski, C. F. Liu, M. McDonell, and, S. D. Fihn,. 2006. " Comparison of Risk Adjustment Measures Based on Self-Report, Administrative Data and Pharmacy Records to Predict Mortality and Hospitalization." Health Services and Outcomes Research Methodology 6 (1-2): 21-36.
7. Gardarsdottir, H., E. R. Heerdink, and, A. C. Egberts,. 2006. " Potential Bias in Pharmacoepidemiological Studies Due to the Length of the Drug Free Period: A Study on Antidepressant Drug Use in Adults in the Netherlands." Pharmacoepidemiol Drug Safety 15 (5): 338-43.
8. Goldman, D. P., G. F. Joyce, and, Y. Zheng,. 2007. " Prescription Drug Cost Sharing: Associations with Medication and Medical Utilization and Spending and Health." Journal of the American Medical Association 298 (1): 61-9.
9. Hess, L. M., M. A. Raebel, D. A. Conner, and, D. C. Malone,. 2006. " Measurement of Adherence in Pharmacy Administrative Databases: A Proposal for Standard Definitions and Preferred Measures." Annals of Pharmacotherapy 40 (7-8): 1280-8.
10. Maciejewski, M. L., C. F. Liu, and, S. D. Fihn,. 2009. " Performance of Comorbidity, Risk Adjustment, and Functional Status Measures in Expenditure Prediction for Patients with Diabetes." Diabetes Care 32 (1): 75-80.
11. Maciejewski, M. L., C. F. Liu, A. Derleth, M. McDonell, S. Anderson, and, S. D. Fihn,. 2005. " The Performance of Administrative and Self-Reported Measures for Risk Adjustment of Veterans Affairs Expenditures." Health Services Research 40: 887-904.
12. Maciejewski, M. L., C. L. Bryson, M. Perkins, D. K. Blough, F. E. Cunningham, J. C. Fortney, S. L. Krein, K. T. Stroupe, N. D. Sharp, and, C. F. Liu,. 2010a. " Increasing Copayments and Adherence to Diabetes, Hypertension and Hyperlipidemic Medications." American Journal of Managed Care 16 (1): e20-32.
13. Maciejewski, M. L., J. F. Farley, J. Parker, and, D. Wansink,. 2010b. " Copayment Reductions Generate Greater Medication Adherence in Targeted Patients." Health Affairs (Millwood) 29 (11).
14. National Quality Forum. 2011. " Compact Action Brief: A Roadmap for Increasing Value in Health Care. Improving Patient Medication Adherence: A $100+ Billion Opportunity." Washington, DC: National Quality Forum.
15. PQA. 2011. " Executive Update on Medication Quality Measures in Medicare Part D Star Ratings." Washington, DC: Pharmacy Quality Alliance.
16. Preen, D. B., C. D. Holman, K. Spilsbury, J. B. Semmens, and, K. J. Brameld,. 2006. " Length of Comorbidity Lookback Period Affected Regression Model Performance of Administrative Health Data." Journal of Clinical Epidemiology 59 (9): 940-6.
17. Ray, W. A., 2003. " Evaluating Medication Effects outside of Clinical Trials: New-User Designs." American Journal of Epidemiology 158 (9): 915-20.
18. Roblin, D. W., R. Platt, M. J. Goodman, J. Hsu, W. W. Nelson, D. H. Smith, S. E. Andrade, and, S. B. Soumerai,. 2005. " Effect of Increased Cost-Sharing on Oral Hypoglycemic Use in Five Managed Care Organizations: How Much Is Too Much? " Medical Care 43 (10): 951-9.
19. Schneeweiss, S., S. B. Soumerai, R. J. Glynn, M. Maclure, C. Dormuth, and, A. M. Walker,. 2002. " Impact of Reference-Based Pricing for Angiotensin-Converting Enzyme Inhibitors on Drug Utilization." Canadian Medical Association Journal 166 (6): 737-45.
20. Shadish, W. R., T. D. Cook, and, D. T. Campbell,. 2002. Experimental and Quasi-Experimental Designs for Generalized Causal Inference. Boston, MA: Houghton Mifflin.
21. Trygstad, T. K., R. A. Hansen, and, S. E. Wegner,. 2006. " Evaluation of Product Switching after a State Medicaid Program Began Covering Loratadine OTC 1 Year after Market Availability." Journal of Managed Care Pharmacy 12 (2): 108-20.
22. Wang, V., C. F. Liu, C. L. Bryson, N. D. Sharp, and, M. L. Maciejewski,. 2011. " Does Medication Adherence Following a Copayment Increase Differ by Disease Burden? " Health Services Research 46 (6 pt 1): 1963-85.
23. Yin, W., A. Basu, J. X. Zhang, A. Rabbani, D. O. Meltzer, and, G. C. Alexander,. 2008. " The Effect of the Medicare Part D Prescription Benefit on Drug Utilization and Expenditures." Annals of Internal Medicine 148 (3): 169-77.
24. Young, B. A., E. Lin, M. Von Korff, G. Simon, P. Ciechanowski, E. J. Ludman, S. Everson-Stewart, L. Kinder, M. Oliver, E. J. Boyko, and, W. J. Katon,. 2008. " Diabetes Complications Severity Index and Risk of Mortality, Hospitalization, and Healthcare Utilization." American Journal of Managed Care 14 (1): 15-23.
25. Zhang, J. X., T. J. Iwashyna, and, N. A. Christakis,. 1999. " The Performance of Different Lookback Periods and Sources of Information for Charlson Comorbidity Adjustment in Medicare Claims." Medical Care 37 (11): 1128-39.