Orthotopic and heterotopic tracheal transplantation model in studying obliterative bronchiolitis

Transplant Immunology

Volumn 28, Issue 4, 2013, Pages 170-175

  Fan, Kai ^a   Qiao, Xin Wei ^a   Nie, Jun ^a   Yuan, Lu ^a   Guo, Hai zhou ^a   Zheng, Zhi kun ^a   Li, Jin song ^a   Wang, Jian Jun ^a   Jiang, Ke ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

Lung transplantation; Obliterative bronchiolitis; Tracheal transplantation

Indexed keywords

AIRWAY OBSTRUCTION; ALLOGRAFT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRONCHIOLITIS OBLITERANS; CD4 CD8 RATIO; CONTROLLED STUDY; FEMALE; HETEROTOPIC TRACHEA TRANSPLANTATION; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; INTRA OMENTAL TRACHEA TRANSPLANTATION; LUNG TRANSPLANTATION; LYMPHOCYTIC INFILTRATION; MONONUCLEAR CELL; MOUSE; MYOFIBROBLAST; NONHUMAN; ORTHOTOPIC TRACHEA TRANSPLANTATION; PRIORITY JOURNAL; SUBCUTANEOUS TRACHEA TRANSPLANTATION; ALLOTRANSPLANTATION; ANGIOGENESIS; ANIMAL; BAGG ALBINO MOUSE; C57BL MOUSE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; HETEROTOPIC TRANSPLANTATION; IMMUNOLOGY; PATHOLOGY; TRACHEA; TRANSPLANTATION;

ANIMALS; BRONCHIOLITIS OBLITERANS; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; FEMALE; LUNG TRANSPLANTATION; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MODELS, ANIMAL; NEOVASCULARIZATION, PHYSIOLOGIC; TRACHEA; TRANSPLANTATION, HETEROTOPIC; TRANSPLANTATION, HOMOLOGOUS;

EID: 84879840718     PISSN: 09663274     EISSN: 18785492     Source Type: Journal    
DOI: 10.1016/j.trim.2013.04.006     Document Type: Article

References (25)

1. Christie J.D., Edwards L.B., Kucheryavaya A.Y., Benden C., Dobbels F., Kirk R., et al. The Registry of the International Society for Heart and Lung Transplantation: twenty-eighth adult lung and heart-lung transplant report-2011. J Heart Lung Transplant 2011, 30:1104-1122.
2. Sundaresan S., Trulock E.P., Mohanakumar T., Cooper J.D., Patterson G.A. Prevalence and outcome of bronchiolitis obliterans syndrome after lung transplantation, Washington University Lung Transplant Group. Ann Thorac Surg 1995, 60:1341-1346. [discussion 6-7].
3. Dutly A.E., Andrade C.F., Verkaik R., Kugathasan L., Trogadis J., Liu M., et al. A novel model for post-transplant obliterative airway disease reveals angiogenesis from the pulmonary circulation. Am J Transplant 2005, 5:248-254.
4. Jungraithmayr W., Kayser G., Haberstroh J., Weder W., Korom S. An experimental approach toward chronic pulmonary allograft rejection: orthotopic lung versus heterotopic tracheal segment transplantation in rats. Transplant Proc 2010, 42:2767-2770.
5. De Vleeschauwer S., Jungraithmayr W., Wauters S., Willems S., Rinaldi M., Vaneylen A., et al. Chronic rejection pathology after orthotopic lung transplantation in mice: the development of a murine BOS model and its drawbacks. PLoS One 2012, 7:e29802.
6. Fan L., Benson H.L., Vittal R., Mickler E.A., Presson R., Fisher A.J., et al. Neutralizing IL-17 prevents obliterative bronchiolitis in murine orthotopic lung transplantation. Am J Transplant 2011, 11:911-922.
7. Hertz M.I., Jessurun J., King M.B., Savik S.K., Murray J.J. Reproduction of the obliterative bronchiolitis lesion after heterotopic transplantation of mouse airways. Am J Pathol 1993, 142:1945-1951.
8. Hua X., Deuse T., Tang-Quan K.R., Robbins R.C., Reichenspurner H., Schrepfer S. Heterotopic and orthotopic tracheal transplantation in mice used as models to study the development of obliterative airway disease. J Vis Exp 2010, (http://www.jove.com/index/Details.stp?ID=1437http://www.ncbi.nlm.nih.gov/pubmed/20090665).
9. Genden E.M., Boros P., Liu J., Bromberg J.S., Mayer L. Orthotopic tracheal transplantation in the murine model. Transplantation 2002, 73:1420-1425.
10. Genden E.M., Iskander A.J., Bromberg J.S., Mayer L. Orthotopic tracheal allografts undergo reepithelialization with recipient-derived epithelium. Arch Otolaryngol Head Neck Surg 2003, 129:118-123.
11. Chen C., Zhang Y.Z., Zheng H., Xu B.B., Gao W. Suppression of the obliteration process by ventilation in a mouse orthotopic tracheal transplantation model. Transplantation 2009, 87:1762-1768.
12. Minamoto K., Pinsky D.J. Recipient iNOS but not eNOS deficiency reduces luminal narrowing in tracheal allografts. J Exp Med 2002, 196:1321-1333.
13. Rock J.R., Randell S.H., Hogan B.L. Airway basal stem cells: a perspective on their roles in epithelial homeostasis and remodeling. Dis Model Mech 2010, 3:545-556.
14. Hele D.J., Yacoub M.H., Belvisi M.G. The heterotopic tracheal allograft as an animal model of obliterative bronchiolitis. Respir Res 2001, 2:169-183.
15. Sato M., Keshavjee S., Liu M. Translational research: animal models of obliterative bronchiolitis after lung transplantation. Am J Transplant 2009, 9:1981-1987.
16. Adams B.F., Brazelton T., Berry G.J., Morris R.E. The role of respiratory epithelium in a rat model of obliterative airway disease. Transplantation 2000, 69:661-664.
17. Neuringer I.P., Aris R.M., Burns K.A., Bartolotta T.L., Chalermskulrat W., Randell S.H. Epithelial kinetics in mouse heterotopic tracheal allografts. Am J Transplant 2002, 2:410-419.
18. Chalermskulrat W., Neuringer I.P., Brickey W.J., Felix N.J., Randell S.H., Ting J.P., et al. Hierarchical contributions of allorecognition pathways in chronic lung rejection. Am J Respir Crit Care Med 2003, 167:999-1007.
19. Babu A.N., Murakawa T., Thurman J.M., Miller E.J., Henson P.M., Zamora M.R., et al. Microvascular destruction identifies murine allografts that cannot be rescued from airway fibrosis. J Clin Invest 2007, 117:3774-3785.
20. Jiang X., Khan M.A., Tian W., Beilke J., Natarajan R., Kosek J., et al. Adenovirus-mediated HIF-1alpha gene transfer promotes repair of mouse airway allograft microvasculature and attenuates chronic rejection. J Clin Invest 2011, 121:2336-2349.
21. Ramirez A.M., Shen Z., Ritzenthaler J.D., Roman J. Myofibroblast transdifferentiation in obliterative bronchiolitis: tgf-beta signaling through smad3-dependent and -independent pathways. Am J Transplant 2006, 6:2080-2088.
22. Hayes D. A review of bronchiolitis obliterans syndrome and therapeutic strategies. J Cardiothorac Surg 2011, 6:92.
23. Yousem S.A., Duncan S.R., Griffith B.P. Interstitial and airspace granulation tissue reactions in lung transplant recipients. Am J Surg Pathol 1992, 16:877-884.
24. Luckraz H., Goddard M., McNeil K., Atkinson C., Sharples L.D., Wallwork J. Is obliterative bronchiolitis in lung transplantation associated with microvascular damage to small airways?. Ann Thorac Surg 2006, 82:1212-1218.
25. Luckraz H., Goddard M., McNeil K., Atkinson C., Charman S.C., Stewart S., et al. Microvascular changes in small airways predispose to obliterative bronchiolitis after lung transplantation. J Heart Lung Transplant 2004, 23:527-531.