Relationship of polymedication in controlling blood pressure: Compliance, persistence, costs and incidence of new cardiovascular events;Relación entre la polimedicación y el control de la presión arterial: cumplimiento, persistencia, costes e incidencia de nuevos eventos cardiovasculares

Medicina Clinica

Volumn 141, Issue 2, 2013, Pages 53-61

  Sicras Mainar, Antoni ^a   Muñoz Ortí, Genís ^b   Font Ramos, Beatriu ^b   Majós Oró, Núria ^b   Navarro Artieda, Ruth ^c   Ibáñez Nolla, Jordi ^a  

^a Badalona Serveis Assistencials SA   (Spain)

^b Department of Epidemiology   (Spain)

^c HOSPITAL UNIVERSITARI GERMANS TRIAS I PUJOL   (Spain)

Author keywords

Compliance; Control; Costs; Hypertension; Incidence; Persistence; Polypharmacy

Indexed keywords

ANTIHYPERTENSIVE AGENT;

AGE DISTRIBUTION; ANTIHYPERTENSIVE THERAPY; ARTICLE; BLOOD PRESSURE REGULATION; CARDIOVASCULAR DISEASE; COMORBIDITY; CONTROLLED STUDY; DEMOGRAPHY; DISEASE SEVERITY; DRUG COST; DRUG USE; FEMALE; HEALTH CARE COST; HUMAN; HYPERTENSION; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY; PATIENT COMPLIANCE; POLYPHARMACY; RETROSPECTIVE STUDY; SOCIAL ASPECT;

COMPLIANCE; CONTROL; COSTES; COSTS; CUMPLIMIENTO; HIPERTENSIÓN ARTERIAL; HYPERTENSION; INCIDENCE; INCIDENCIA; PERSISTENCE; PERSISTENCIA; POLIFARMACIA; POLYPHARMACY;

ABSENTEEISM; AGED; ANTIHYPERTENSIVE AGENTS; BLOOD PRESSURE; CARDIOVASCULAR DISEASES; COMORBIDITY; DIAGNOSTIC TESTS, ROUTINE; DRUG RESISTANCE; DRUG THERAPY, COMBINATION; FEMALE; HEALTH CARE COSTS; HEALTH RESOURCES; HUMANS; HYPERTENSION; INCIDENCE; MALE; MEDICATION ADHERENCE; MIDDLE AGED; MODELS, ECONOMIC; OFFICE VISITS; PATIENT COMPLIANCE; POLYPHARMACY; RETROSPECTIVE STUDIES; SOCIOECONOMIC FACTORS; SPAIN; TREATMENT OUTCOME;

EID: 84879837164     PISSN: 00257753     EISSN: 15788989     Source Type: Journal    
DOI: 10.1016/j.medcli.2012.04.026     Document Type: Article

References (45)

1. J.R. Banegas, A. Jovell, B. Abarca, M. Aguilar Diosdado, L. Aguilera, and P. Aranda Hipertensión y política sanitaria en España Med Clin (Barc) 132 2009 222 229
2. World Health Organization The World Health Report 2002: reducing risk, promoting healthy life 2002 World Health Organization Geneve
3. J.R. Banegas Epidemiología de la hipertensión arterial en España. Situación actual y perspectivas Hipertensión 22 2005 353 362
4. A. Coca, P. Aranda, V. Bertomeu, A. Bonet, E. Esmatjes, and F. Guillén Estrategias para un control eficaz de la hipertensión arterial en España. Documento de Consenso Hipertensión 23 2006 152 156
5. G. Mancia, G. De Backer, A. Dominiczak, R. Cifkova, R. Fagard, G. Germano Management of Arterial Hypertension of the European Society of Hypertension; European Society of Cardiology 2007 Guidelines for the Management of Arterial Hypertension: The Task Force for the Management of Arterial Hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC) J Hypertens 25 2007 1105 1187
6. A. De la Sierra, M. Gorostidi, R. Marín, J. Redón, J.R. Banegas, and P. Armario Evaluación y tratamiento de la hipertensión arterial en España. Documento de consenso Med Clin (Barc) 131 2008 104 116
7. J.L. Llisterri Caro, G.C. Rodríguez Roca, F.J. Alonso Moreno, S. Lou Arnal, J.A. Divisón Garrote, and J.A. Santos Rodríguez Control de la presión arterial en la población hipertensa española atendida en atención primaria. Estudio PRESCAP 2002 Med Clin (Barc) 122 2004 165 171
8. G. Mancia, S. Laurent, E. Agabiti-Rosei, E. Ambrosioni, M. Burnier, M.J. Caulfield European Society of Hypertension Reappraisal of European guidelines on hypertension management: a European Society of Hypertension Task Force document J Hypertens 27 2009 2121 2158
9. J. Ceral, V. Habrdova, V. Vorisek, M. Bima, R. Pelouch, and M. Solar Difficult-to-control arterial hypertension or uncooperative patients. The assessment of serum antihypertensive drug levels to differentiate non-responsiveness from non-adherence to recommended therapy Hypertens Res 34 2011 87 90
10. J. Segura de la Morena, J.A. García Donaire, and L.R. Ruilope Urioste Nuevas estrategias terapéuticas para mejorar el control de la hipertensión arterial y simplificar la pauta de tratamiento farmacológico Med Clin (Barc) 134 2010 635 642
11. J.L. Llisterri Caro, and V. Barrios Alonso Papel de las nuevas combinaciones a dosis fijas en el tratamiento de la hipertensión arterial Med Clin (Barc) 130 2008 342 344
12. J.F. Bergmann Review: fixed-dose drug combinations improve medication compliance compared with free-drug regimens Evid Based Med 13 2008 18
13. A. Khanna, L. Lefkowitz, and W.B. White Evaluation of recent fixed-dose combination therapies in the management of hypertension Curr Opin Nephrol Hypertens 17 2008 477 483
14. G.L. Plosker, and W.B. White Telmisartan/Hydrochlorothiazide: a review of its use as fixed-dose combinations in essential hypertension Drugs 68 2008 1877 1899
15. K. McKeage, and M.A. Siddiqui Amlodipine/atorvastatin fixed-dose combination: a review of its use in the prevention of cardiovascular disease and in the treatment of hypertension and dyslipidemia Am J Cardiovasc Drugs 8 2008 51 67
16. A.K. Gupta, S. Arshad, and N.R. Poulter Compliance, safety, and effectiveness of fixed-dose combinations of antihypertensive agents: a meta-analysis Hypertension 55 2010 399 407
17. E.C. Yiannakopoulou, J.S. Papadopulos, D.V. Cokkinos, and T.D. Mountokalakis Adherence to antihypertensive treatment: a critical factor for blood pressure control Eur J Cardiovasc Prev Rehabil 12 2005 243 249
18. B.V. Patel, R.A. Remigio-Baker, P. Thiebaud, R. Preblick, and C. Plauschinat Improved persistence and adherence to diuretic fixed-dose combination therapy compared to diuretic monotherapy BMC Fam Pract 9 2008 61
19. E. Márquez Contreras, J.J. Casado Martínez, M. de la Figuera Won-Vichman, V. Gil Guillén, N. Martell en representación del grupo de cumplimiento de la Sociedad Española de la HTA-LELHA El incumplimiento terapéutico en el tratamiento de la hipertensión arterial en España. Análisis de los estudios publicados entre 1984 y 2001 Hipertensión 19 2002 12 16
20. A. Sicras-Mainar, and R. Navarro-Artieda Coste de la hipertensión arterial según grados de morbilidad en atención primaria Med Clin (Barc) 133 2009 290 295
21. N. Sood, K.M. Reinhart, and W.L. Baker Combination therapy for the management of hypertension: A review of the evidence Am J Health Syst Pharm 67 2010 885 894
22. S. Erdine Compliance with the treatment of hypertension: the potential of combination therapy J Clin Hypertens (Greenwich) 12 2010 40 46
23. D. Cooney, and K. Pascuzzi Polypharmacy in the elderly: focus on drug interactions and adherence in hypertension Clin Geriatr Med 25 2009 221 233
24. P.J. Helmons, L.N. Wargel, and C.E. Daniels Effect of bar-code-assisted medication administration on medication administration errors and accuracy in multiple patient care areas Am J Health Syst Pharm 66 2009 1202 1210
25. H. Lamberts, M. Wood, and I.M. Hofmans-Okkes The International Classification of Primary Care in the European Community. With a multi-language layer 1993 Oxford University Press Oxford
26. Guidelines for ATC classification 1991 Nordic Collaborating Centre for Drug Statistics Methodology Oslo
27. S. Bangalore, G. Kamalakkannan, S. Parkar, and F.H. Messerli Fixed-dose combinations improve medication compliance: a meta-analysis Am J Med 120 2007 713 719
28. M.E. Charlson, P. Pompei, K.L. Ales, and C.R. Mackenzie A new method of classifying prognostic comorbidity in longitudinal studies: development and validation J Chronic Dis 40 1987 373 383
29. J.P. Weiner, B.H. Starfield, D.M. Steinwachs, and L.M. Mumford Development and application of a population-oriented measure of ambulatory care case-mix Med Care 29 1991 452 472
30. S.G. Thompson, and J.A. Barber How should cost data in pragmatic randomised trials be analysed? BMJ 320 2000 1197 1200
31. P.M. Rothwell Limitations of the usual blood-pressure hypothesis and importance of variability, instability, and episodic hypertension Lancet 375 2010 938 948
32. A. Villafaina, and E. Gavilán Polimedicación e inadecuación farmacológica Pharm Care Esp 13 2011 23 29
33. M.A. Munger Polypharmacy and combination therapy in the management of hypertension in elderly patients with co-morbid diabetes mellitus Drugs Aging 27 2010 871 883
34. W.C. Gerth Compliance and persistence with newer antihypertensive agents Curr Hypertens Rep 4 2002 424 433
35. B.L. Van Wijk, O.H. Klungel, E.R. Heerdink, and A. de Boer Rate and determinants of 10-year persistence with antihypertensive drugs J Hypertens 23 2005 2101 2107
36. P.R. Conlin, W.C. Gerth, J. Fox, J.B. Roehm, and S.J. Boccuzzi Four-year persistence patterns among patients initiating therapy with the angiotensin ii receptor antagonist losartan versus other antihypertensive drug classes Clin Ther 23 2001 1999 2010
37. M.R. Law, N.J. Wald, J.K. Morris, and R.E. Jordan Value of low dose combination treatment with blood pressure lowering drugs: analysis of 354 randomised trials BMJ 326 2003 1427
38. W. Golden, S.G. Potts, D.S. West, T. Kinggard Arkansas Foundation for Medical Care Toward better control of hypertension: targeting patient compliance J Ark Med Soc 104 2007 36 37
39. T.G. Pickering Why are we doing so badly with the control of hypertension? Poor compliance is only part of the story J Clin Hypertens (Greenwich) 3 2001 179 182
40. T.J. Bramley, P.P. Gerbino, B.S. Nightengale, and F. Frech-Tamas Relationship of blood pressure control to adherence with antihypertensive monotherapy in 13 managed care organizations J Manag Care Pharm 12 2006 239 245
41. M.T. Halpern, Z.M. Khan, J.K. Schmier, M. Burnier, J.J. Caro, and J. Cramer Recommendations for evaluating compliance and persistence with hypertension therapy using retrospective data Hypertension 47 2006 1039 1048
42. I. Saito, H. Suzuki, S. Kageyama, and T. Saruta Effect of antihypertensive treatment on cardiovascular events in elderly hypertensive patients: Japan's Benidipine Research on Antihypertensive Effects in the Elderly (J-BRAVE) Clin Exp Hypertens 33 2011 133 140
43. L. Harmon, R.J. Chilton, and C. Spellman Reducing cardiovascular events and end-organ damage in patients with hypertension: new considerations Postgrad Med 123 2011 7 17
44. M.C. Sokol, K.A. McGuigan, R.R. Verbrugge, and R.S. Epstein Impact of medication adherence on hospitalization risk and healthcare cost Med Care 43 2005 521 530
45. V. Stankus, B. Hemmelgarn, N.R. Campbell, G. Chen, F.A. McAlister, and R.T. Tsuyuki Reducing costs and improving hypertension management Can J Clin Pharmacol 16 2009 e151 e155