Ion selectivity and competition in channelrhodopsins

Biophysical Journal

Volumn 105, Issue 1, 2013, Pages 91-100

  Schneider, Franziska ^a   Gradmann, Dietrich ^b   Hegemann, Peter ^a  

^a HUMBOLDT UNIVERSITY   (Germany)

^b UNIVERSITY OF GÖTTINGEN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CHANNELRHODOPSIN 2, HUMAN; METAL; PROTON; RHODOPSIN;

ARTICLE; BINDING COMPETITION; BIOLOGICAL MODEL; CELL STRAIN HEK293; CHANNEL GATING; CHEMISTRY; ELECTRIC CONDUCTIVITY; ENZYME SPECIFICITY; HUMAN; LIGHT; METABOLISM; RADIATION EXPOSURE;

BINDING, COMPETITIVE; ELECTRIC CONDUCTIVITY; HEK293 CELLS; HUMANS; ION CHANNEL GATING; LIGHT; METALS; MODELS, BIOLOGICAL; PROTONS; RHODOPSIN; SUBSTRATE SPECIFICITY;

CHLOROPHYTA;

EID: 84879835185     PISSN: 00063495     EISSN: 15420086     Source Type: Journal    
DOI: 10.1016/j.bpj.2013.05.042     Document Type: Article

References (25)

1. G. Nagel, and D. Ollig P. Hegemann Channelrhodopsin-1: a light-gated proton channel in green algae Science 296 2002 2395 2398
2. G. Nagel, and T. Szellas E. Bamberg Channelrhodopsin-2, a directly light-gated cation-selective membrane channel Proc. Natl. Acad. Sci. USA 100 2003 13940 13945
3. E.S. Boyden, and F. Zhang K. Deisseroth Millisecond-timescale, genetically targeted optical control of neural activity Nat. Neurosci. 8 2005 1263 1268
4. X. Li, and D.V. Gutierrez S. Herlitze Fast noninvasive activation and inhibition of neural and network activity by vertebrate rhodopsin and green algae channelrhodopsin Proc. Natl. Acad. Sci. USA 102 2005 17816 17821
5. G. Nagel, and T. Szellas E. Bamberg Channelrhodopsins: directly light-gated cation channels Biochem. Soc. Trans. 33 2005 863 866
6. P. Hegemann, S. Ehlenbeck, and D. Gradmann Multiple photocycles of channelrhodopsin Biophys. J. 89 2005 3911 3918
7. K. Nikolic, P. Degenaar, and C. Toumazou Modeling and engineering aspects of channelrhodopsin2 system for neural photostimulation IEEE Eng. Med. Biol. Soc. 1 2006 1626 1629
8. K. Nikolic, and N. Grossman P. Degenaar Photocycles of channelrhodopsin-2 Photochem. Photobiol. 85 2009 400 411
9. A. Berndt, and M. Prigge P. Hegemann Two open states with progressive proton selectivities in the branched channelrhodopsin-2 photocycle Biophys. J. 98 2010 753 761
10. D. Gradmann, and A. Berndt P. Hegemann Rectification of the channelrhodopsin early conductance Biophys. J. 101 2011 1057 1068
11. D. Gradmann, and C.M. Boyd Apparent charge of binding site in ion-translocating enzymes: kinetic impact Eur Biophys J. 34 2005 353 357
12. F. Zhang, and M. Prigge K. Deisseroth Red-shifted optogenetic excitation: a tool for fast neural control derived from Volvox carteri Nat. Neurosci. 11 2008 631 633
13. S.P. Tsunoda, and P. Hegemann Glu 87 of channelrhodopsin-1 causes pH-dependent color tuning and fast photocurrent inactivation Photochem. Photobiol. 85 2009 564 569
14. M. Prigge, and F. Schneider P. Hegemann Color-tuned channelrhodopsins for multiwavelength optogenetics J. Biol. Chem. 287 2012 31804 31812
15. C. Bamann, and R. Gueta E. Bamberg Structural guidance of the photocycle of channelrhodopsin-2 by an interhelical hydrogen bond Biochemistry 49 2010 267 278
16. + channel in the tonoplast of Chara: selectivity and inhibition J. Membr. Biol. 132 1993 253 265
17. E.L. King, and C. Altman A schematic method of deriving the rate laws for enzyme-catalyzed reactions J. Phys. Chem. 60 1956 1375 1378
18. A. Berndt, and P. Schoenenberger T.G. Oertner High-efficiency channelrhodopsins for fast neuronal stimulation at low light levels Proc. Natl. Acad. Sci. USA 108 2011 7595 7600
19. +-permeable channelrhodopsin CatCh Nat. Neurosci. 14 2011 513 518
20. S. Ullrich, R. Gueta, and G. Nagel Degradation of channelopsin-2 in the absence of retinal and degradation resistance in certain mutants Biol. Chem. 394 2012 271 280
21. O. Yizhar, and L.E. Fenno K. Deisseroth Neocortical excitation/inhibition balance in information processing and social dysfunction Nature 477 2011 171 178
22. H. Wang, and Y. Sugiyama H. Yawo Molecular determinants differentiating photocurrent properties of two channelrhodopsins from Chlamydomonas J. Biol. Chem. 284 2009 5685 5696
23. J.Y. Lin, and M.Z. Lin R.Y. Tsien Characterization of engineered channelrhodopsin variants with improved properties and kinetics Biophys. J. 96 2009 1803 1814
24. T.J. Schoenmakers, and G.J. Visser A.P. Theuvenet CHELATOR: an improved method for computing metal ion concentrations in physiological solutions Biotechniques 12 1992 870 874 876-879
25. J. Mattis, and K.M. Tye K. Deisseroth Principles for applying optogenetic tools derived from direct comparative analysis of microbial opsins Nat. Methods 9 2012 159 172