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Volumn 27, Issue 6, 2013, Pages 351-363

A meta-analysis of adjuvant therapy after potentially curative treatment for hepatocellular carcinoma

Author keywords

Adjuvant therapy; Hepatocellular carcinoma; Recurrence; Survival

Indexed keywords

ALPHA INTERFERON; BETA INTERFERON; CANCER VACCINE; CAPECITABINE; CARMOFUR; CISPLATIN; DOXORUBICIN; EPIRUBICIN; FLUOROURACIL; MENATETRENONE; MITOMYCIN; PERETINOIN; PI 88; RETINOL; UFT;

EID: 84879802731     PISSN: 08357900     EISSN: None     Source Type: Journal    
DOI: 10.1155/2013/417894     Document Type: Review
Times cited : (53)

References (75)
  • 1
    • 78049485263 scopus 로고    scopus 로고
    • Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008
    • Ferlay J, Shin HR, Bray F, et al. Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008. Int J Cancer 2010;127:2893-917.
    • (2010) Int J Cancer , vol.127 , pp. 2893-2917
    • Ferlay, J.1    Shin, H.R.2    Bray, F.3
  • 2
    • 34248176226 scopus 로고    scopus 로고
    • Hepatitis B in China
    • DOI 10.1016/S0140-6736(07)60723-5, PII S0140673607607235
    • Liu J, Fan D. Hepatitis B in China. Lancet 2007;369:1582-3. (Pubitemid 46710107)
    • (2007) Lancet , vol.369 , Issue.9573 , pp. 1582-1583
    • Liu, J.1    Fan, D.2
  • 3
    • 11144356989 scopus 로고    scopus 로고
    • A decade's studies on metastasis of hepatocellular carcinoma
    • Tang ZY, Ye SL, Liu YK, et al. A decade's studies on metastasis of hepatocellular carcinoma. J Cancer Res Clin Oncol 2004;130:187-96.
    • (2004) J Cancer Res Clin Oncol , vol.130 , pp. 187-196
    • Tang, Z.Y.1    Ye, S.L.2    Liu, Y.K.3
  • 4
    • 77954334672 scopus 로고    scopus 로고
    • Meta-analysis of radiofrequency ablation versus hepatic resection for small hepatocellular carcinoma
    • Zhou Y, Zhao Y, Li B, et al. Meta-analysis of radiofrequency ablation versus hepatic resection for small hepatocellular carcinoma. BMC Gastroenterol 2010;10:78.
    • (2010) BMC Gastroenterol , vol.10 , pp. 78
    • Zhou, Y.1    Zhao, Y.2    Li, B.3
  • 5
    • 33644662778 scopus 로고    scopus 로고
    • A prospective randomized trial comparing percutaneous local ablative therapy and partial hepatectomy for small hepatocellular carcinoma
    • DOI 10.1097/01.sla.0000201480.65519.b8
    • Chen MS, Li JQ, Zheng Y, et al. A prospective randomized trial comparing percutaneous local ablative therapy and partial hepatectomy for small hepatocellular carcinoma. Ann Surg 2006;243:321-8. (Pubitemid 43327762)
    • (2006) Annals of Surgery , vol.243 , Issue.3 , pp. 321-328
    • Chen, M.-S.1    Li, J.-Q.2    Zheng, Y.3    Guo, R.-P.4    Liang, H.-H.5    Zhang, Y.-Q.6    Lin, X.-J.7    Lau, W.Y.8
  • 6
    • 0038460305 scopus 로고    scopus 로고
    • Liver Resection for Hepatocellular Carcinoma on Cirrhosis: Univariate and Multivariate Analysis of Risk Factors for Intrahepatic Recurrence
    • DOI 10.1097/00000658-200304000-00016
    • Ercolani G, Grazi GL, Ravaioli M, et al. Liver resection for hepatocellular carcinoma on cirrhosis: Univariate and multivariate analysis of risk factors for intrahepatic recurrence. Ann Surg 2003;237:536-43. (Pubitemid 38176435)
    • (2003) Annals of Surgery , vol.237 , Issue.4 , pp. 536-543
    • Ercolani, G.1    Grazi, G.L.2    Ravaioli, M.3    Del, G.M.4    Gardini, A.5    Cescon, M.6    Varotti, G.7    Cetta, F.8    Cavallari, A.9
  • 7
    • 0036189906 scopus 로고    scopus 로고
    • Long-term survival and pattern of recurrence after resection of small hepatocellular carcinoma in patients with preserved liver function: Implications for a strategy of salvage transplantation
    • DOI 10.1097/00000658-200203000-00009
    • Poon RT, Fan ST, Lo CM, et al. Long-term survival and pattern of recurrence after resection of small hepatocellular carcinoma in patients with preserved liver function: Implications for a strategy of salvage transplantation. Ann Surg 2002;235:373-82. (Pubitemid 34183888)
    • (2002) Annals of Surgery , vol.235 , Issue.3 , pp. 373-382
    • Poon, R.T.-P.1    Sheung, T.F.2    Chung, M.L.3    Chi, L.L.4    Wong, J.5
  • 8
    • 40849124295 scopus 로고    scopus 로고
    • Novel advancements in the management of hepatocellular carcinoma in 2008
    • Llovet JM, Bruix J. Novel advancements in the management of hepatocellular carcinoma in 2008. J Hepatol 2008;48 Suppl 1:S20-37.
    • (2008) J Hepatol , vol.48 , Issue.SUPPL. 1
    • Llovet, J.M.1    Bruix, J.2
  • 9
    • 77957603190 scopus 로고    scopus 로고
    • Hepatocellular carcinoma: Consensus recommendations of the National Cancer Institute Clinical Trials Planning Meeting
    • Thomas MB, Jaffe D, Choti MM, et al. Hepatocellular carcinoma: Consensus recommendations of the National Cancer Institute Clinical Trials Planning Meeting. J Clin Oncol 2010;28:3994-4005.
    • (2010) J Clin Oncol , vol.28 , pp. 3994-4005
    • Thomas, M.B.1    Jaffe, D.2    Choti, M.M.3
  • 10
    • 0036799144 scopus 로고    scopus 로고
    • Neoadjuvant and adjuvant therapy for resectable hepatocellular carcinoma: Review of the randomised clinical trials
    • DOI 10.1016/S1470-2045(02)00873-2
    • Schwartz JD, Schwartz M, Mandeli J, et al. Neoadjuvant and adjuvant therapy for resectable hepatocellular carcinoma: Review of the randomised clinical trials. Lancet Oncol 2002;3:593-603. (Pubitemid 35174678)
    • (2002) Lancet Oncology , vol.3 , Issue.10 , pp. 593-603
    • Schwartz, J.D.1    Schwartz, M.2    Mandeli, J.3    Sung, M.4
  • 11
    • 0038639294 scopus 로고    scopus 로고
    • Preventive treatments for recurrence after curative resection of hepatocellular carcinoma - A literature review of randomized control trials
    • Sun HC, Tang ZY. Preventive treatments for recurrence after curative resection of hepatocellular carcinoma - a literature review of randomized control trials. World J Gastroenterol 2003;9:635-40.
    • (2003) World J Gastroenterol , vol.9 , pp. 635-640
    • Sun, H.C.1    Tang, Z.Y.2
  • 13
    • 64949153532 scopus 로고    scopus 로고
    • The current role of neoadjuvant/adjuvant/chemoprevention therapy in partial hepatectomy for hepatocellular carcinoma: A systematic review
    • Lau WY, Lai EC, Lau SH. The current role of neoadjuvant/adjuvant/ chemoprevention therapy in partial hepatectomy for hepatocellular carcinoma: A systematic review. Hepatobiliary Pancreat Dis Int 2009;8:124-33.
    • (2009) Hepatobiliary Pancreat Dis Int , vol.8 , pp. 124-133
    • Lau, W.Y.1    Lai, E.C.2    Lau, S.H.3
  • 14
    • 67649237427 scopus 로고    scopus 로고
    • Neoadjuvant and adjuvant therapy for surgical resection of hepatocellular carcinoma
    • Samuel M, Chow PK, Chan Shih-Yen E, et al. Neoadjuvant and adjuvant therapy for surgical resection of hepatocellular carcinoma. Cochrane Database Syst Rev 2009;CD001199.
    • (2009) Cochrane Database Syst Rev
    • Samuel, M.1    Chow, P.K.2    Chan Shih-Yen, E.3
  • 15
    • 0035876465 scopus 로고    scopus 로고
    • Adjuvant chemotherapy after resection of hepatocellular carcinoma causes deterioration of long-term prognosis in cirrhotic patients: Metaanalysis of three randomized controlled trials
    • DOI 10.1002/1097-0142(20010615)91:12<2378::AID-CNC
    • Ono T, Yamanoi A, Nazmy El Assal O, et al. Adjuvant chemotherapy after resection of hepatocellular carcinoma causes deterioration of long-term prognosis in cirrhotic patients: Metaanalysis of three randomized controlled trials. Cancer 2001;91:2378-85. (Pubitemid 32552825)
    • (2001) Cancer , vol.91 , Issue.12 , pp. 2378-2385
    • Ono, T.1    Yamanoi, A.2    El, A.O.N.3    Kohno, H.4    Nagasue, N.5
  • 16
    • 77957242266 scopus 로고    scopus 로고
    • Postoperative adjuvant transarterial chemoembolization for participants with hepatocellular carcinoma: A meta-analysis
    • Zhong JH, Li LQ. Postoperative adjuvant transarterial chemoembolization for participants with hepatocellular carcinoma: A meta-analysis. Hepatol Res 2010;40:943-53.
    • (2010) Hepatol Res , vol.40 , pp. 943-953
    • Zhong, J.H.1    Li, L.Q.2
  • 17
    • 69249110100 scopus 로고    scopus 로고
    • Systematic review and meta-analysis of interferon after curative treatment of hepatocellular carcinoma in patients with viral hepatitis
    • Breitenstein S, Dimitroulis D, Petrowsky H, et al. Systematic review and meta-analysis of interferon after curative treatment of hepatocellular carcinoma in patients with viral hepatitis. Br J Surg 2009;96:975-81.
    • (2009) Br J Surg , vol.96 , pp. 975-981
    • Breitenstein, S.1    Dimitroulis, D.2    Petrowsky, H.3
  • 18
    • 65649140040 scopus 로고    scopus 로고
    • Effects of interferon alpha treatment on recurrence and survival after complete resection or ablation of hepatocellular carcinoma: A meta-analysis of randomized controlled trials
    • Zhang CH, Xu GL, Jia WD, et al. Effects of interferon alpha treatment on recurrence and survival after complete resection or ablation of hepatocellular carcinoma: A meta-analysis of randomized controlled trials. Int J Cancer 2009;124:2982-8.
    • (2009) Int J Cancer , vol.124 , pp. 2982-2988
    • Zhang, C.H.1    Xu, G.L.2    Jia, W.D.3
  • 19
    • 77954266287 scopus 로고    scopus 로고
    • Postoperative adjuvant antiviral therapy for hepatitis B/C virus-related hepatocellular carcinoma: A meta-analysis
    • Miao RY, Zhao HT, Yang HY, et al. Postoperative adjuvant antiviral therapy for hepatitis B/C virus-related hepatocellular carcinoma: A meta-analysis. World J Gastroenterol 2010;16:2931-42.
    • (2010) World J Gastroenterol , vol.16 , pp. 2931-2942
    • Miao, R.Y.1    Zhao, H.T.2    Yang, H.Y.3
  • 20
    • 77950220516 scopus 로고    scopus 로고
    • Meta-analysis: Interferon-alpha prevents the recurrence after curative treatment of hepatitis C virus-related hepatocellular carcinoma
    • Miyake Y, Takaki A, Iwasaki Y, et al. Meta-analysis: Interferon-alpha prevents the recurrence after curative treatment of hepatitis C virus-related hepatocellular carcinoma. J Viral Hepat 2010;17:287-92.
    • (2010) J Viral Hepat , vol.17 , pp. 287-292
    • Miyake, Y.1    Takaki, A.2    Iwasaki, Y.3
  • 21
    • 77952422635 scopus 로고    scopus 로고
    • Adjuvant interferon therapy after curative therapy for hepatocellular carcinoma (HCC): A meta-regression approach
    • Shen YC, Hsu C, Chen LT, et al. Adjuvant interferon therapy after curative therapy for hepatocellular carcinoma (HCC): A meta-regression approach. J Hepatol 2010;52:889-94.
    • (2010) J Hepatol , vol.52 , pp. 889-894
    • Shen, Y.C.1    Hsu, C.2    Chen, L.T.3
  • 22
    • 77956397191 scopus 로고    scopus 로고
    • Meta-analysis: Interferon improves outcomes following ablation or resection of hepatocellular carcinoma
    • Singal AK, Freeman DH, Jr., Anand BS. Meta-analysis: interferon improves outcomes following ablation or resection of hepatocellular carcinoma. Aliment Pharmacol Ther 2010;32:851-8.
    • (2010) Aliment Pharmacol Ther , vol.32 , pp. 851-858
    • Singal, A.K.1    Freeman Jr., D.H.2    Anand, B.S.3
  • 23
    • 79954906552 scopus 로고    scopus 로고
    • Meta-analysis: The efficacy of anti-viral therapy in prevention of recurrence after curative treatment of chronic hepatitis B-related hepatocellular carcinoma
    • Wong JS, Wong GL, Tsoi KK, et al. Meta-analysis: The efficacy of anti-viral therapy in prevention of recurrence after curative treatment of chronic hepatitis B-related hepatocellular carcinoma. Aliment Pharmacol Ther 2011;33:1104-12.
    • (2011) Aliment Pharmacol Ther , vol.33 , pp. 1104-1112
    • Wong, J.S.1    Wong, G.L.2    Tsoi, K.K.3
  • 24
    • 78650350171 scopus 로고    scopus 로고
    • Vitamin analogues in chemoprevention of hepatocellular carcinoma after resection or ablation - A systematic review and meta-analysis
    • Chu KJ, Lai EC, Yao XP, et al. Vitamin analogues in chemoprevention of hepatocellular carcinoma after resection or ablation - a systematic review and meta-analysis. Asian J Surg 2010;33:120-6.
    • (2010) Asian J Surg , vol.33 , pp. 120-126
    • Chu, K.J.1    Lai, E.C.2    Yao, X.P.3
  • 25
    • 0032583387 scopus 로고    scopus 로고
    • Extracting summary statistics to perform meta-analyses of the published literature for survival endpoints
    • DOI 10.1002/(SICI)1097-0258(19981230)17:24<2815::A
    • Parmar MK, Torri V, Stewart L. Extracting summary statistics to perform meta-analyses of the published literature for survival endpoints. Stat Med 1998;17:2815-34. (Pubitemid 28562978)
    • (1998) Statistics in Medicine , vol.17 , Issue.24 , pp. 2815-2834
    • Parmar, M.K.B.1    Torri, V.2    Stewart, L.3
  • 26
    • 34547450763 scopus 로고    scopus 로고
    • Practical methods for incorporating summary time-to-event data into meta-analysis
    • Tierney JF, Stewart LA, Ghersi D, et al. Practical methods for incorporating summary time-to-event data into meta-analysis. Trials 2007;8:16.
    • (2007) Trials , vol.8 , pp. 16
    • Tierney, J.F.1    Stewart, L.A.2    Ghersi, D.3
  • 28
    • 0034255520 scopus 로고    scopus 로고
    • Different risk factors and prognosis for early and late intrahepatic recurrence after resection of hepatocellular carcinoma
    • DOI 10.1002/1097-0142(20000801)89:3<500::AID-CNCR4
    • Poon RT, Fan ST, Ng IO, et al. Different risk factors and prognosis for early and late intrahepatic recurrence after resection of hepatocellular carcinoma. Cancer 2000;89:500-7. (Pubitemid 30640096)
    • (2000) Cancer , vol.89 , Issue.3 , pp. 500-507
    • Poon, R.T.-P.1    Fan, S.-T.2    Ng, I.O.-L.3    Lo, C.-M.4    Liu, C.-L.5    Wong, J.6
  • 29
    • 0034002470 scopus 로고    scopus 로고
    • Long-term prognosis after resection of hepatocellular carcinoma associated with hepatitis B-related cirrhosis
    • Poon RT, Fan ST, Lo CM, et al. Long-term prognosis after resection of hepatocellular carcinoma associated with hepatitis B-related cirrhosis. J Clin Oncol 2000;18:1094-101. (Pubitemid 30123788)
    • (2000) Journal of Clinical Oncology , vol.18 , Issue.5 , pp. 1094-1101
    • Poon, R.T.-P.1    Fan, S.-T.2    Lo, C.-M.3    Liu, C.-L.4    Ng, I.O.-L.5    Wong, J.6
  • 30
    • 0033798983 scopus 로고    scopus 로고
    • Surgical indications for advanced hepatocellular carcinoma
    • Shimada M, Yamashita Y, Hamatsu T, et al. Surgical indications for advanced hepatocellular carcinoma. Hepatogastroenterology 2000;47:1095-9.
    • (2000) Hepatogastroenterology , vol.47 , pp. 1095-1099
    • Shimada, M.1    Yamashita, Y.2    Hamatsu, T.3
  • 33
    • 0030012773 scopus 로고    scopus 로고
    • Adjuvant oral chemotherapy to prevent recurrence after curative resection for hepatocellular carcinoma
    • DOI 10.1002/bjs.1800830313
    • Yamamoto M, Arii S, Sugahara K, et al. Adjuvant oral chemotherapy to prevent recurrence after curative resection for hepatocellular carcinoma. Br J Surg 1996;83:336-40. (Pubitemid 26083165)
    • (1996) British Journal of Surgery , vol.83 , Issue.3 , pp. 336-340
    • Yamamoto, M.1    Arii, S.2    Sugahara, K.3    Tobe, T.4
  • 35
    • 78650984411 scopus 로고    scopus 로고
    • Adjuvant therapy with capecitabine postpones recurrence of hepatocellular carcinoma after curative resection: A randomized controlled trial
    • Xia Y, Qiu Y, Li J, et al. Adjuvant therapy with capecitabine postpones recurrence of hepatocellular carcinoma after curative resection: A randomized controlled trial. Ann Surg Oncol 2010;17:3137-44.
    • (2010) Ann Surg Oncol , vol.17 , pp. 3137-3144
    • Xia, Y.1    Qiu, Y.2    Li, J.3
  • 36
    • 84989592159 scopus 로고
    • Postoperative adjuvant hepatic arterial infusion of lipiodol containing anticancer drugs in patients with hepatocellular carcinoma
    • DOI 10.1016/0270-9139(94)90177-5
    • Izumi R, Shimizu K, Iyobe T, et al. Postoperative adjuvant hepatic arterial infusion of Lipiodol containing anticancer drugs in patients with hepatocellular carcinoma. Hepatology 1994;20:295-301. (Pubitemid 24233352)
    • (1994) Hepatology , vol.20 , Issue.2 , pp. 295-301
    • Izumi, R.1    Shimizu, K.2    Iyobe, T.3    Ii, T.4    Yagi, M.5    Matsui, O.6    Nonomura, A.7    Miyazaki, I.8
  • 37
    • 0033565280 scopus 로고    scopus 로고
    • Postoperative prediction of and strategy for metastatic recurrent hepatocellular carcinoma according to histologic activity of hepatitis
    • DOI 10.1002/(SICI)1097-0142(19990715)86:2<248::AID
    • Ueno S, Tanabe G, Yoshida A, et al. Postoperative prediction of and strategy for metastatic recurrent hepatocellular carcinoma according to histologic activity of hepatitis. Cancer 1999;86:248-54. (Pubitemid 29327581)
    • (1999) Cancer , vol.86 , Issue.2 , pp. 248-254
    • Ueno, S.1    Tanabe, G.2    Yoshida, A.3    Yoshidome, S.4    Takao, S.5    Aikou, T.6
  • 39
    • 0031914335 scopus 로고    scopus 로고
    • Postoperative adjuvant chemotherapy after curative resection of hepatocellular carcinoma: A randomized controlled trial
    • DOI 10.1001/archsurg.133.2.183
    • Lai EC, Lo CM, Fan ST, et al. Postoperative adjuvant chemotherapy after curative resection of hepatocellular carcinoma: A randomized controlled trial. Arch Surg 1998;133:183-8. (Pubitemid 28092919)
    • (1998) Archives of Surgery , vol.133 , Issue.2 , pp. 183-188
    • Lai, E.C.S.1    Lo, C.-M.2    Fan, S.-T.3    Liu, C.-L.4    Wong, J.5
  • 40
    • 0030979388 scopus 로고    scopus 로고
    • Adjuvant chemotherapy with epirubicin and carmofur after radical resection of hepatocellular carcinoma: A prospective randomized study
    • Ono T, Nagasue N, Kohno H, et al. Adjuvant chemotherapy with epirubicin and carmofur after radical resection of hepatocellular carcinoma: A prospective randomized study. Semin Oncol 1997;24:S6-18-S6-25.
    • (1997) Semin Oncol , vol.24
    • Ono, T.1    Nagasue, N.2    Kohno, H.3
  • 41
    • 0033854015 scopus 로고    scopus 로고
    • Interferon beta prevents recurrence of hepatocellular carcinoma after complete resection or ablation of the primary tumor - A prospective randomized study of hepatitis C virus - Related liver cancer
    • Ikeda K, Arase Y, Saitoh S, et al. Interferon beta prevents recurrence of hepatocellular carcinoma after complete resection or ablation of the primary tumor-A prospective randomized study of hepatitis C virus-related liver cancer. Hepatology 2000;32:228-32. (Pubitemid 30614654)
    • (2000) Hepatology , vol.32 , Issue.2 , pp. 228-232
    • Ikeda, K.1    Arase, Y.2    Saitoh, S.3    Kobayashi, M.4    Suzuki, Y.5    Suzuki, F.6    Tsubota, A.7    Chayama, K.8    Murashima, N.9    Kumada, H.10
  • 43
    • 0036271549 scopus 로고    scopus 로고
    • Randomized clinical trial of long-term outcome after resection of hepatitis C virus-related hepatocellular carcinoma by postoperative interferon therapy
    • DOI 10.1046/j.0007-1323.2001.02054.x
    • Kubo S, Nishiguchi S, Hirohashi K, et al. Randomized clinical trial of long-term outcome after resection of hepatitis C virus-related hepatocellular carcinoma by postoperative interferon therapy. Br J Surg 2002;89:418-22. (Pubitemid 34595504)
    • (2002) British Journal of Surgery , vol.89 , Issue.4 , pp. 418-422
    • Kubo, S.1    Nishiguchi, S.2    Hirohashi, K.3    Tanaka, H.4    Shuto, T.5    Kinoshita, H.6
  • 44
    • 17244373744 scopus 로고    scopus 로고
    • Effect of long-term postoperative interferon therapy on intrahepatic recurrence and survival rate after resection of hepatitis C virus-related hepatocellular carcinoma
    • DOI 10.1159/000082098
    • Nishiguchi S, Tamori A, Kubo S. Effect of long-term postoperative interferon therapy on intrahepatic recurrence and survival rate after resection of hepatitis C virus-related hepatocellular carcinoma. Intervirology 2005;48:71-5. (Pubitemid 40529214)
    • (2005) Intervirology , vol.48 , Issue.1 , pp. 71-75
    • Nishiguchi, S.1    Tamori, A.2    Kubo, S.3
  • 46
    • 0346093899 scopus 로고    scopus 로고
    • Prospective randomized controlled study of interferon-alpha in preventing hepatocellular carcinoma recurrence after medical ablation therapy for primary tumors
    • Lin SM, Lin CJ, Hsu CW, et al. Prospective randomized controlled study of interferon-alpha in preventing hepatocellular carcinoma recurrence after medical ablation therapy for primary tumors. Cancer 2004;100:376-82.
    • (2004) Cancer , vol.100 , pp. 376-382
    • Lin, S.M.1    Lin, C.J.2    Hsu, C.W.3
  • 48
    • 33646736379 scopus 로고    scopus 로고
    • Postoperative interferon alpha treatment postponed recurrence and improved overall survival in patients after curative resection of HBV-related hepatocellular carcinoma: A randomized clinical trial
    • Sun HC, Tang ZY, Wang L, et al. Postoperative interferon alpha treatment postponed recurrence and improved overall survival in patients after curative resection of HBV-related hepatocellular carcinoma: A randomized clinical trial. J Cancer Res Clin Oncol 2006;132:458-65.
    • (2006) J Cancer Res Clin Oncol , vol.132 , pp. 458-465
    • Sun, H.C.1    Tang, Z.Y.2    Wang, L.3
  • 49
    • 34249316548 scopus 로고    scopus 로고
    • A randomized, controlled trial of postoperative adjuvant interferon therapy after resection of hepatocellular carcinoma
    • DOI 10.1097/01.sla.0000245829.00977.45, PII 0000065820070600000001
    • Lo CM, Liu CL, Chan SC, et al. A randomized, controlled trial of postoperative adjuvant interferon therapy after resection of hepatocellular carcinoma. Ann Surg 2007;245:831-42. (Pubitemid 46809282)
    • (2007) Annals of Surgery , vol.245 , Issue.6 , pp. 831-842
    • Lo, C.M.1    Liu, C.L.2    Chan, S.C.3    Lam, C.M.4    Poon, R.T.P.5    Ng, I.O.L.6    Fan, S.T.7    Wong, J.8
  • 51
    • 0033118925 scopus 로고    scopus 로고
    • Prevention of second primary tumors by an acyclic retinoid in patients with hepatocellular carcinoma [4]
    • DOI 10.1056/NEJM199904013401315
    • Muto Y, Moriwaki H, Saito A. Prevention of second primary tumors by an acyclic retinoid in patients with hepatocellular carcinoma. N Engl J Med 1999;340:1046-7. (Pubitemid 29157643)
    • (1999) New England Journal of Medicine , vol.340 , Issue.13 , pp. 1046-1047
    • Muto, Y.1    Moriwaki, H.2    Saito, A.3
  • 52
    • 32544446614 scopus 로고    scopus 로고
    • The effect of menatetrenone, a vitamin K2 analog, on disease recurrence and survival in patients with hepatocellular carcinoma after curative treatment: A pilot study
    • DOI 10.1002/cncr.21667
    • Mizuta T, Ozaki I, Eguchi Y, et al. The effect of menatetrenone, a vitamin K2 analog, on disease recurrence and survival in patients with hepatocellular carcinoma after curative treatment: A pilot study. Cancer 2006;106:867-72. (Pubitemid 43238454)
    • (2006) Cancer , vol.106 , Issue.4 , pp. 867-872
    • Mizuta, T.1    Ozaki, I.2    Eguchi, Y.3    Yasutake, T.4    Kawazoe, S.5    Fujimoto, K.6    Yamamoto, K.7
  • 53
    • 37749011807 scopus 로고    scopus 로고
    • Effect of vitamin K2 on the recurrence in patients with hepatocellular carcinoma
    • Hotta N, Ayada M, Sato K, et al. Effect of vitamin K2 on the recurrence in patients with hepatocellular carcinoma. Hepatogastroenterology 2007;54:2073-7.
    • (2007) Hepatogastroenterology , vol.54 , pp. 2073-2077
    • Hotta, N.1    Ayada, M.2    Sato, K.3
  • 55
    • 79960744370 scopus 로고    scopus 로고
    • Effect of vitamin K2 on the recurrence of hepatocellular carcinoma
    • Yoshida H, Shiratori Y, Kudo M, et al. Effect of vitamin K2 on the recurrence of hepatocellular carcinoma. Hepatology 2011;54:532-40.
    • (2011) Hepatology , vol.54 , pp. 532-540
    • Yoshida, H.1    Shiratori, Y.2    Kudo, M.3
  • 56
    • 0034596475 scopus 로고    scopus 로고
    • Adoptive immunotherapy to lower postsurgical recurrence rates of hepatocellular carcinoma: A randomised trial
    • Takayama T, Sekine T, Makuuchi M, et al. Adoptive immunotherapy to lower postsurgical recurrence rates of hepatocellular carcinoma: A randomised trial. Lancet 2000;356:802-7.
    • (2000) Lancet , vol.356 , pp. 802-807
    • Takayama, T.1    Sekine, T.2    Makuuchi, M.3
  • 57
    • 40749152776 scopus 로고    scopus 로고
    • Minimally invasive treatment combined with cytokine-induced killer cells therapy lower the short-term recurrence rates of hepatocellular carcinomas
    • DOI 10.1097/CJI.0b013e31815a121b, PII 0000237120080100000008
    • Weng DS, Zhou J, Zhou QM, et al. Minimally invasive treatment combined with cytokine-induced killer cells therapy lower the short-term recurrence rates of hepatocellular carcinomas. J Immunother 2008;31:63-71. (Pubitemid 351619405)
    • (2008) Journal of Immunotherapy , vol.31 , Issue.1 , pp. 63-71
    • Weng, D.-S.1    Zhou, J.2    Zhou, Q.-M.3    Zhao, M.4    Wang, Q.-J.5    Huang, L.-X.6    Li, Y.-Q.7    Chen, S.-P.8    Wu, P.-H.9    Xia, J.-C.10
  • 58
    • 57449105089 scopus 로고    scopus 로고
    • A randomized, controlled trial of postoperative adjuvant cytokine-induced killer cells immunotherapy after radical resection of hepatocellular carcinoma
    • Hui D, Qiang L, Jian W, et al. A randomized, controlled trial of postoperative adjuvant cytokine-induced killer cells immunotherapy after radical resection of hepatocellular carcinoma. Dig Liver Dis 2009;41:36-41.
    • (2009) Dig Liver Dis , vol.41 , pp. 36-41
    • Hui, D.1    Qiang, L.2    Jian, W.3
  • 61
    • 37549046808 scopus 로고    scopus 로고
    • Adjuvant intra-arterial iodine-131-labeled lipiodol for resectable hepatocellular carcinoma: A prospective randomized trial-update on 5-year and 10-year survival
    • Lau WY, Lai EC, Leung TW, et al. Adjuvant intra-arterial iodine-131-labeled lipiodol for resectable hepatocellular carcinoma: A prospective randomized trial-update on 5-year and 10-year survival. Ann Surg 2008;247:43-8.
    • (2008) Ann Surg , vol.247 , pp. 43-48
    • Lau, W.Y.1    Lai, E.C.2    Leung, T.W.3
  • 63
    • 84984569951 scopus 로고    scopus 로고
    • Heparanase inhibitor PI-88 as adjuvant therapy for hepatocellular carcinoma after curative resection: A randomized phase II trial for safety and optimal dosage
    • Liu CJ, Lee PH, Lin DY, et al. Heparanase inhibitor PI-88 as adjuvant therapy for hepatocellular carcinoma after curative resection: A randomized phase II trial for safety and optimal dosage. J Hepatol 2009;50:958-68.
    • (2009) J Hepatol , vol.50 , pp. 958-968
    • Liu, C.J.1    Lee, P.H.2    Lin, D.Y.3
  • 64
    • 79955863760 scopus 로고    scopus 로고
    • Serum alpha-fetoprotein measurement in predicting clinical outcome related to autologous cytokine-induced killer cells in patients with hepatocellular carcinoma undergone minimally invasive therapy
    • Pan CC, Huang ZL, Li W, et al. Serum alpha-fetoprotein measurement in predicting clinical outcome related to autologous cytokine-induced killer cells in patients with hepatocellular carcinoma undergone minimally invasive therapy. Chin J Cancer 2010;29:596-602.
    • (2010) Chin J Cancer , vol.29 , pp. 596-602
    • Pan, C.C.1    Huang, Z.L.2    Li, W.3
  • 65
    • 69449100622 scopus 로고    scopus 로고
    • Preferred reporting items for systematic reviews and meta-analyses: The PRISMA statement
    • Moher D, Liberati A, Tetzlaff J, et al. Preferred reporting items for systematic reviews and meta-analyses: The PRISMA statement. BMJ 2009;339:b2535.
    • (2009) BMJ , vol.339
    • Moher, D.1    Liberati, A.2    Tetzlaff, J.3
  • 66
    • 33745547361 scopus 로고    scopus 로고
    • New therapies for hepatocellular carcinoma
    • DOI 10.1038/sj.onc.1209550, PII 1209550
    • Avila MA, Berasain C, Sangro B, et al. New therapies for hepatocellular carcinoma. Oncogene 2006;25:3866-84. (Pubitemid 43980482)
    • (2006) Oncogene , vol.25 , Issue.27 , pp. 3866-3884
    • Avila, M.A.1    Berasain, C.2    Sangro, B.3    Prieto, J.4
  • 67
    • 0028876371 scopus 로고
    • Randomised trial of effects of interferon-alpha on incidence of hepatocellular carcinoma in chronic active hepatitis C with cirrhosis
    • Nishiguchi S, Kuroki T, Nakatani S, et al. Randomised trial of effects of interferon-alpha on incidence of hepatocellular carcinoma in chronic active hepatitis C with cirrhosis. Lancet 1995;346:1051-5.
    • (1995) Lancet , vol.346 , pp. 1051-1055
    • Nishiguchi, S.1    Kuroki, T.2    Nakatani, S.3
  • 70
    • 0033862041 scopus 로고    scopus 로고
    • Chromosomal changes and clonality relationship between primary and recurrent hepatocellular carcinoma
    • Chen YJ, Yeh SH, Chen JT, et al. Chromosomal changes and clonality relationship between primary and recurrent hepatocellular carcinoma. Gastroenterology 2000;119:431-40.
    • (2000) Gastroenterology , vol.119 , pp. 431-440
    • Chen, Y.J.1    Yeh, S.H.2    Chen, J.T.3
  • 71
    • 0037371545 scopus 로고    scopus 로고
    • Determination of the molecular relationship between multiple tumour nodules in hepatocellular carcinoma differentiates multicentric origin from intrahepatic metastasis
    • DOI 10.1002/path.1287
    • Ng IO, Guan XY, Poon RT, et al. Determination of the molecular relationship between multiple tumour nodules in hepatocellular carcinoma differentiates multicentric origin from intrahepatic metastasis. J Pathol 2003;199:345-53. (Pubitemid 36266857)
    • (2003) Journal of Pathology , vol.199 , Issue.3 , pp. 345-353
    • Ng, I.O.-L.1    Guan, X.-Y.2    Poon, R.T.-P.3    Fan, S.T.4    Lee, J.M.-F.5
  • 72
    • 0037102254 scopus 로고    scopus 로고
    • Identify metastasis-associated genes in hepatocellular carcinoma through clonality delineation for multinodular tumor
    • Cheung ST, Chen X, Guan XY, et al. Identify metastasis-associated genes in hepatocellular carcinoma through clonality delineation for multinodular tumor. Cancer Res 2002;62:4711-21.
    • (2002) Cancer Res , vol.62 , pp. 4711-4721
    • Cheung, S.T.1    Chen, X.2    Guan, X.Y.3
  • 73
    • 33750096548 scopus 로고    scopus 로고
    • General and statistical hierarchy of appropriate biologic endpoints
    • Williston Park
    • Sargent D. General and statistical hierarchy of appropriate biologic endpoints. Oncology (Williston Park) 2006;20:5-9.
    • (2006) Oncology , vol.20 , pp. 5-9
    • Sargent, D.1
  • 74
    • 44449085884 scopus 로고    scopus 로고
    • Design and endpoints of clinical trials in hepatocellular carcinoma
    • Llovet JM, Di Bisceglie AM, Bruix J, et al. Design and endpoints of clinical trials in hepatocellular carcinoma. J Natl Cancer Inst 2008;100:698-711.
    • (2008) J Natl Cancer Inst , vol.100 , pp. 698-711
    • Llovet, J.M.1    Di Bisceglie, A.M.2    Bruix, J.3


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