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Volumn 9, Issue 10, 2012, Pages 934-941

Microwave assisted synthesis, characterization of some new isatin and thiophene derivatives as cytotoxic and chemopreventive agents

Author keywords

Carbohydrazide; Cytotoxic activity; Epstein Barr virus antigen (EBV EA) activation; Isatin; Thiocarbohydrazide; Thiophene 2 carboxaldehyde

Indexed keywords

EPSTEIN BARR VIRUS ANTIGEN; ISATIN DERIVATIVE; THIOPHENE DERIVATIVE;

EID: 84870410959     PISSN: 15701808     EISSN: 1875628X     Source Type: Journal    
DOI: 10.2174/157018012804586950     Document Type: Article
Times cited : (21)

References (33)
  • 1
    • 77952810921 scopus 로고    scopus 로고
    • Recent applications of microwave irradiation to medicinal chemistry
    • Alcazar, J.; Oehlrich, D. Recent applications of microwave irradiation to medicinal chemistry. Future Med. Chem. 2010, 2(2), 169-176.
    • (2010) Future Med. Chem. , vol.2 , Issue.2 , pp. 169-176
    • Alcazar, J.1    Oehlrich, D.2
  • 3
    • 84858705973 scopus 로고    scopus 로고
    • Iodine-catalyzed condensation of isatin with indoles: A facile synthesis of di(indolyl)indolin-2-ones and evaluation of their cytotoxicity
    • Subba Reddy, B.V.; Rajeswari, N.; Sarangapani, M.; Prashanthi, Y.; Roopa Jones, G.; Anothony, A. Iodine-catalyzed condensation of isatin with indoles: A facile synthesis of di(indolyl)indolin-2-ones and evaluation of their cytotoxicity. Biorg. Med. Chem. Lett., 2012, 22, 2460-2463.
    • (2012) Biorg. Med. Chem. Lett. , vol.22 , pp. 2460-2463
    • Subba Reddy, B.V.1    Rajeswari, N.2    Sarangapani, M.3    Prashanthi, Y.4    Roopa Jones, G.5    Anothony, A.6
  • 4
    • 84871410487 scopus 로고    scopus 로고
    • Synthesis and antidepressant activity of di substituted-5-aryl-1,2,4- triazoles
    • Radhika, C.; Venkatesham, A.; Sarangapani, M. Synthesis and antidepressant activity of di substituted-5-aryl-1,2,4-triazoles. Med. Chem. Res., 2011, 1-5.
    • (2011) Med. Chem. Res. , pp. 1-5
    • Radhika, C.1    Venkatesham, A.2    Sarangapani, M.3
  • 5
    • 28144443339 scopus 로고    scopus 로고
    • N-benzylisatin sulfonamide analogues as potent caspase-3 inhibitors: Synthesis, in vitro activity, and molecular modeling studies
    • DOI 10.1021/jm0506625
    • Chu, W.; Zhang, J.; Zeng, C.; Rothfuss, J.; Tu, Z.; Reichert, D.E.; Welch, M.J.; Mach, R.H. N-Benzylisatin sulfonamide analogues as potent caspase-3 inhibitors: synthesis, in vitro activity, and molecular modeling studies. J. Med. Chem., 2005, 48, 7637-7647. (Pubitemid 41698804)
    • (2005) Journal of Medicinal Chemistry , vol.48 , Issue.24 , pp. 7637-7647
    • Chu, W.1    Zhang, J.2    Zeng, C.3    Rothfuss, J.4    Tu, Z.5    Chu, Y.6    Reichert, D.E.7    Welch, M.J.8    Mach, R.H.9
  • 6
    • 65249096525 scopus 로고    scopus 로고
    • Synthesis and in vitro evaluation of sulfonamide isatin michael acceptors as small molecule inhibitors of caspase-6
    • Chu, W.; Rothfuss, J.; Chu, Y.; Zhou, D.; Mach, R. H. Synthesis and in vitro evaluation of sulfonamide isatin michael acceptors as small molecule inhibitors of caspase-6. J. Med. Chem., 2009, 52, 2188-2191.
    • (2009) J. Med. Chem. , vol.52 , pp. 2188-2191
    • Chu, W.1    Rothfuss, J.2    Chu, Y.3    Zhou, D.4    MacH, R.H.5
  • 8
    • 17444427138 scopus 로고    scopus 로고
    • Combinatorial optimization of isatin-β-thiosemicarbazones as anti-poxvirus agents
    • DOI 10.1021/jm049147h
    • Pirrung, M.C.; Pansare, S.V.; Das Sarma, K.; Keith, K.A.; Kern, E.R. Combinatorial Optimization of Isatin-3-thiosemicarbazones as Anti-pox virus Agents. J. Med. Chem., 2005, 48, 3045-3050. (Pubitemid 40548116)
    • (2005) Journal of Medicinal Chemistry , vol.48 , Issue.8 , pp. 3045-3050
    • Pirrung, M.C.1    Pansare, S.V.2    Das Sarma, K.3    Keith, K.A.4    Kern, E.R.5
  • 11
    • 84870441565 scopus 로고    scopus 로고
    • Isatins inhibit cyclooxygenase-2 and inducible nitric oxide synthase in a mouse macrophage cell line
    • Matheus, M.E.; Violante, F.; Garden, S.J.; Pinto, A.C.; Fernandes, P.D. Isatins inhibit cyclooxygenase-2 and inducible nitric oxide synthase in a mouse macrophage cell line. Eur.J.Pharm., 2007, 49, 3440-3443.
    • (2007) Eur.J.Pharm. , vol.49 , pp. 3440-3443
    • Matheus, M.E.1    Violante, F.2    Garden, S.J.3    Pinto, A.C.4    Fernandes, P.D.5
  • 12
    • 33745176602 scopus 로고    scopus 로고
    • Isatin compounds as noncovalent SARS coronavirus 3C-like protease inhibitors
    • DOI 10.1021/jm0602357
    • Zhou, L.; Liu, Y.; Zhang, W.; Wei, P.; Huang, C.; Pei, J.; Yaun, Y.; Lai, L. Isatin compounds as noncovalant SARS coronavirus 3Clike protease inhibitors. J. Med. Chem., 2006, 49, 3440-3443. (Pubitemid 43902449)
    • (2006) Journal of Medicinal Chemistry , vol.49 , Issue.12 , pp. 3440-3443
    • Zhou, L.1    Liu, Y.2    Zhang, W.3    Wei, P.4    Huang, C.5    Pei, J.6    Yuan, Y.7    Lai, L.8
  • 13
    • 34548401633 scopus 로고    scopus 로고
    • Synthesis, antibacterial, antifungal and antiviral activity evaluation of some new bis-schiff bases of isatin and their derivatives
    • Jarrahpour, A.; Khalili, D.; De Clercq, E.; Salmi, S.; Brunel, J.M. Synthesis, antibacterial, antifungal and antiviral activity evaluation of some new bis-schiff bases of isatin and their derivatives. Molecules., 2007, 12, 1720-1730.
    • (2007) Molecules. , vol.12 , pp. 1720-1730
    • Jarrahpour, A.1    Khalili, D.2    De Clercq, E.3    Salmi, S.4    Brunel, J.M.5
  • 14
    • 0347084611 scopus 로고    scopus 로고
    • Some pharmacological activities of new substituted pyrolloindoles, indolothiazepine and azole derivatives
    • Sharaf, O.A. Some pharmacological activities of new substituted pyrolloindoles, indolothiazepine and azole derivatives. Bull. Fac. Pharm., 1997, 35, 79-82.
    • (1997) Bull. Fac. Pharm. , vol.35 , pp. 79-82
    • Sharaf, O.A.1
  • 15
    • 1942488330 scopus 로고    scopus 로고
    • Anticonvulsant activity of Schiff bases of isatin derivatives
    • Verma, M.; Pandey, S.N.; Singh, K.N.; Stables, J.P. Anticonvulsant activity of Schiff bases of isatin derivatives. Acta Pharm., 2004, 54, 49-56. (Pubitemid 38524314)
    • (2004) Acta Pharmaceutica , vol.54 , Issue.1 , pp. 49-56
    • Verma, M.1    Pandeya, S.N.2    Singh, K.N.3    Stables, J.P.4
  • 17
    • 0028001561 scopus 로고
    • Inhibition of human immunodeficiency virus by N-methylisatinbeta 4′:4′-diethylthiosemicarbazone and N-allylisatin-beta-4′: 4′-dially thiosemicarbazone
    • Teitz, Y.; Ronen, D.; Vansover, A.; Stematsky, T.; Riggs, J. L. Inhibition of human immunodeficiency virus by N-methylisatinbeta 4′:4′-diethylthiosemicarbazone and N-allylisatin-beta-4′: 4′-dially thiosemicarbazone. Antiviral Res., 1994, 24, 305-314.
    • (1994) Antiviral Res. , vol.24 , pp. 305-314
    • Teitz, Y.1    Ronen, D.2    Vansover, A.3    Stematsky, T.4    Riggs, J.L.5
  • 18
    • 0014734997 scopus 로고
    • Chemistry of carbohydrazide and thiocarbohydrazide
    • Kurzer, F; Wilkinson, M. Chemistry of carbohydrazide and thiocarbohydrazide Chem. Rev., 1970, 70(1), 111-149.
    • (1970) Chem. Rev. , vol.70 , Issue.1 , pp. 111-149
    • Kurzer, F.1    Wilkinson, M.2
  • 19
    • 80052810801 scopus 로고    scopus 로고
    • Synthesis, properties and biological activity of thiophene: A review
    • Raghav, M.; Jha, K.K.; Sachin. K.; Isha Tomer. Synthesis, properties and biological activity of thiophene: A review. Der Pharma Chemica., 2011, 3(4), 38-54.
    • (2011) Der Pharma Chemica. , vol.3 , Issue.4 , pp. 38-54
    • Raghav, M.1    Jha, K.K.2    Sachin, K.3    Tomer, I.4
  • 21
    • 84965812126 scopus 로고
    • The mechanism of carcinogenesis. A study of the significance of cocarcinogenic action and related phenomena
    • Berenblum, I. The mechanism of carcinogenesis. A study of the significance of cocarcinogenic action and related phenomena. Cancer Res., 1941, 1, 807-814.
    • (1941) Cancer Res. , vol.1 , pp. 807-814
    • Berenblum, I.1
  • 23
    • 11444267327 scopus 로고    scopus 로고
    • Rexinoids may be ready for prime time in prevention, but challenges remain
    • Hede, K.; Rexinoids may be ready for prime time in prevention, but challenges remain. J. Natl. Cancer.Inst., 2004, 96(24), 1807-1808. (Pubitemid 40081311)
    • (2004) Journal of the National Cancer Institute , vol.96 , Issue.24 , pp. 1807-1808
    • Hede, K.1
  • 26
    • 77956691146 scopus 로고    scopus 로고
    • Optimization of the production of thiocarbohydrazide using the Taguchi method
    • Zhou, J.; Wu, D.; Gou, D. J. Optimization of the production of thiocarbohydrazide using the Taguchi method. Chem Technol Biotechnol., 2010, 85(10), 1402-1406.
    • (2010) Chem Technol Biotechnol. , vol.85 , Issue.10 , pp. 1402-1406
    • Zhou, J.1    Wu, D.2    Gou, D.J.3
  • 27
    • 0025869827 scopus 로고
    • Abdel-Hady. Reactions of isatin with thiocarbohydrazide
    • Mohamed, Badawy A.; Sayed A, Abdel-Hady. Reactions of isatin with thiocarbohydrazide. Arch. Pharm.(Weinheim), 1991,324, 349-352.
    • (1991) Arch. Pharm.(Weinheim) , vol.324 , pp. 349-352
    • Mohamed Badawy, A.1    Sayed, A.2
  • 28
    • 0020454904 scopus 로고
    • 5-Substituted 2'-deoxyuridines: Correlation between inhibition of tumor cell growth and inhibition of thymidine kinase and thymidylate synthetase
    • DOI 10.1016/0006-2952(82)90594-9
    • Balzarini, J.; De Clercq, E.; Mertes, M.P.; Shugar, D.; Torrence, P.F. 5-Substituted 2'-deoxy uridines: correlation between inhibition of tumor cell growth and inhibition of thymidine kinase and thymidylate synthetase. Biochem. Pharmacol., 1982, 31, 3673- 3682. (Pubitemid 13244137)
    • (1982) Biochemical Pharmacology , vol.31 , Issue.22 , pp. 3673-3682
    • Balzarini, J.1    De Clercq, E.2    Mertes, M.P.3
  • 29
    • 0035976047 scopus 로고    scopus 로고
    • Cancer chemopreventive agents, serratane-type triterpenoids from Picea jezoensis
    • DOI 10.1016/S0304-3835(01)00650-4, PII S0304383501006504
    • Tanaka, T.; Minami, T.; Tsujimoto, K.; Matsunaga, S.; Tokuda, H.; Nishino, H.; Terada, Y.; Yoshitake, A. Cancer chemopreventive agents, serratane-type triterpenoids from Picea jezoensis Cancer Lett. 2001, 172(2), 119-126. (Pubitemid 32889705)
    • (2001) Cancer Letters , vol.172 , Issue.2 , pp. 119-126
    • Tanaka, R.1    Minami, T.2    Tsujimoto, K.3    Matsunaga, S.4    Tokuda, H.5    Nishino, H.6    Terada, Y.7    Yoshitake, A.8
  • 30
    • 0013891274 scopus 로고
    • Immunofluorescence in cells derived from Burkitt's Lymphoma
    • Henle, G.; Henle, W. Immunofluorescence in cells derived from Burkitt's Lymphoma. J. Bacteriol., 1966, 91, 1248-1256.
    • (1966) J. Bacteriol. , vol.91 , pp. 1248-1256
    • Henle, G.1    Henle, W.2
  • 31
    • 0002175935 scopus 로고
    • De Vita, V.T.; Busch H; Ed., Academic Press: New York
    • Suffness, M.; Dourus, J In: De Vita, V.T.; Busch H; Ed. Methods in Cancer Research. Part A, Academic Press: New York, 1979, Vol 16, pp 84-96.
    • (1979) Methods in Cancer Research. Part A , vol.16 , pp. 84-96
    • Suffness, M.1    Dourus, J.2
  • 32
    • 0029008108 scopus 로고
    • Retinoid chemoprevention of aerodigestive cancer: From basic research to the clinic
    • Hong, W.K.; Lippman, S.M.; Hittleman, W.N.; Lotan, R. Retinoid chemoprevention of aerodigestive cancer: from basic research to the clinic. Clin. Cancer Res., 1995, 1,677-686.
    • (1995) Clin. Cancer Res. , vol.1 , pp. 677-686
    • Hong, W.K.1    Lippman, S.M.2    Hittleman, W.N.3    Lotan, R.4


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