Risk factors for non-melanoma skin cancer in kidney transplant patients in a Spanish population in the Mediterranean region

Acta Dermato-Venereologica

Volumn 93, Issue 4, 2013, Pages 422-427

  Bernat García, Josefa ^a   Morales Suárez Varela, Maria ^b   Vilata, Juan J ^c   Marquina, Amparo ^a   Pallardó, Luis ^a   Crespo, Josep ^a  

^a HOSPITAL UNIVERSITARIO DR PESET   (Spain)

^b UNIVERSITY OF VALENCIA   (Spain)

^c HOSPITAL GENERAL UNIVERSITARIO DE VALENCIA   (Spain)

Author keywords

Immunosuppression; Renal; Risk factors; Skin cancer; Sun exposure; Transplant

Indexed keywords

LEUKOCYTE ANTIGEN; MAMMALIAN TARGET OF RAPAMYCIN INHIBITOR;

ACTINIC KERATOSIS; ADOLESCENT; ADULT; AGED; ALCOHOL CONSUMPTION; ARTICLE; BASAL CELL CARCINOMA; DIALYSIS; DISEASE ASSOCIATION; ENVIRONMENTAL FACTOR; EXPOSURE; EYE COLOR; FAMILY HISTORY; FEMALE; FOLLOW UP; GRAFT RECIPIENT; HUMAN; IMMUNOSUPPRESSIVE TREATMENT; KIDNEY TRANSPLANTATION; MAJOR CLINICAL STUDY; MALE; NON MELANOMA SKIN CANCER; OBSERVATIONAL STUDY; OCCUPATIONAL EXPOSURE; PRIORITY JOURNAL; RETROSPECTIVE STUDY; RISK FACTOR; SKIN EXAMINATION; SMOKING; SOUTHERN EUROPE; SPAIN; SQUAMOUS CELL CARCINOMA; STRUCTURED INTERVIEW; VERRUCA VULGARIS;

ADOLESCENT; ADULT; AGE FACTORS; AGED; BIOPSY; CARCINOMA, BASAL CELL; CARCINOMA, SQUAMOUS CELL; FEMALE; HUMANS; IMMUNOSUPPRESSIVE AGENTS; INCIDENCE; KAPLAN-MEIER ESTIMATE; KIDNEY TRANSPLANTATION; MALE; MEDITERRANEAN REGION; MIDDLE AGED; MULTIVARIATE ANALYSIS; OCCUPATIONAL EXPOSURE; PRECANCEROUS CONDITIONS; PROPORTIONAL HAZARDS MODELS; PROSPECTIVE STUDIES; QUESTIONNAIRES; RETROSPECTIVE STUDIES; RISK ASSESSMENT; RISK FACTORS; SKIN NEOPLASMS; SPAIN; SUNLIGHT; TIME FACTORS; YOUNG ADULT;

EID: 84879719364     PISSN: 00015555     EISSN: 16512057     Source Type: Journal    
DOI: 10.2340/00015555-1525     Document Type: Article

References (24)

1. Fuente MJ, Sabat M, Roca J, Lauzurica R, Fernández- Figueras MT, Ferrándiz C. A prospective study of the incidence of skin cancer and its risk factors in a Spanish Mediterranean population of kidney transplant recipients. Br J Dermatol 2003; 149: 1221-1226
2. Moloney FJ, Comber H, O'Lorcain P, O'Kelly P, Conlon PJ, Murphy GM. A population-based study of skin cancer incidence and prevalence in renal transplant recipientes. Br J Dermatol 2006; 154: 498-504
3. Zwald FO, Brown M. Skin cancer in solid organ transplant recipients: advances in therapy and management. Part I. Epidemiology of skin cancer in solid organ transplant recipients. J Am Acad Dermatol 2011; 65: 253-261
4. Ho WL, Murphy GM. Update on the pathogenesis of posttransplant skin cancer in renal transplant recipients. Br J Dermatol 2008; 158: 217-224
5. Bordea C, Wojnarowska F, Millard PR, Doll H, Welsh K, Morris PJ. Skin cancers in renal-transplant recipients occur more frequently than previously recognized in a temperate climate. Transplantation 2004; 77: 574-579
6. Ramsay HM, Fryer AA, Hawley CM, Smith AG, Harden PN. Non-melanoma skin cancer risk in the Queensland renal transplant population. Br J Dermatol 2002; 147: 950-956
7. Ramsay HM, Fryer AA, Hawley CM, Smith AG, Nicol DL, Harden PN, et al. Factors associated with nonmelanoma skin cancer following renal transplantation in Queensland, Australia. J Am Acad Dermatol 2003; 49: 397-406
8. Otley CC, Cherikh WS, Salasche SJ, McBride MA, Christenson LJ, Kauffman HM. Skin cancer in organ transplant recipients: effect of pretransplant end-organ disease. J Am Acad Dermatol 2005; 53: 783-790
9. Jensen AO, Svaerke C, Farkas D, Pedersen L, Kragballe K, Sørensen HT. Skin cancer risk among solid organ recipients: a nationwide cohort study in Denmark. Acta Derm Venereol 2010; 90: 474-479
10. Bouwes Bavinck JN, Vermeer BJ, van der Woude FJ, Vandenbroucke JP, Schreuder GM, Thorogood J, et al. Relation between skin cancer and HLA antigens in renal-transplant recipients. N Engl J Med 1991; 325: 843-848
11. Bouwes Bavinck JN, Kootte AM, Van Der Woude FJ, Vandenbroucke JP, Vermeer BJ, Claas FH. On a possible protective effect of HLA-A11 against skin cancer and keratotic skin lesions in renal transplant recipients. J Invest Dermatol 1991; 97: 269-272
12. Czarnecki D, Zalcberg J, Nicholson I, Tait B. Skin cancer and HLA antigens. N Engl J Med 1992; 326: 765-766
13. Bouwes Bavinck JN, Claas FH, Hardie DR, Green A, Vermeer BJ, Hardie IR. Relation between HLA antigens and skin cancer in renal transplant recipients in Queensland, Australia. J Invest Dermatol 1997; 108: 708-711
14. Bock A, Bliss RL, Matas A, Little JA. Human leukocyte antigen type as a risk factor for nonmelanomatous skin cancer in patients after renal transplantation. Transplantation 2004; 78: 775-778
15. Bouwes Bavinck JN, Euvrard S, Naldi L, Nindl I, Proby CM, Neale R, et al. Keratotic skin lesions and other risk factors are associated with skin cancer in organ-transplant recipients: a case-control study in The Netherlands, United Kingdom, Germany, France, and Italy. J Invest Dermatol 2007; 127: 1647-1656
16. Arron ST, Ruby JG, Dybbro E, Ganem D, Derisi JL. Transcriptome sequencing demonstrates that human papillomavirus is not active in cutaneous squamous cell carcinoma. J Invest Dermatol 2011; 131: 1745-1753
17. Harwood CA, Surentheran T, McGregor JM, Spink PJ, Leigh IM, Breuer J, et al. Human papillomavirus infection and non-melanoma skin cancer in immunosuppressed and immunocompetent individuals. J Med Virol 2000; 61: 289-297
18. Kauffman HM, Cherikh WS, Cheng Y, Hanto DW, Kahan BD. Maintenance immuosuppression with target-of-rapamycin inhibitors is associated with a reduced incidence of de novo malignancies. Transplantation 2005; 80: 883-889
19. Yakupoglu YK, Buell JF, Woodle S, Kahan BD. Individualization of immunosupressive therapy. III. Sirolimus associated with a reduced incidence of malignancy. Transplant Proc 2006; 38: 358-361
20. Fernández A, Marcén R, Pascual J, Galeano C, Ocaña J, Arellano EM, et al. Conversion from calcineurin inhibitors to everolimus in kidney transplant recipients with malignant neoplasia. Transplant Proc 2006; 38: 2453-2455
21. De Fitjer JW. Use of proliferation signal inhibitors in nonmelanoma skin cancer following renal transplantation. Nephrol Dial Transplant 2007; 22: 23-26
22. Mathew T, Kreis H, Friend P. Two-year incidence of malignancy in sirolimus-treated renal transplant recipients: results from five multicenter studies. Clin Transplant 2004; 18: 446-449
23. Geusau A, Dunkler D, Messeritsch E, Sandor N, Heidler G, Rödler S, et al. Non-melanoma skin cancer and its risk factors in an Austrian population of heart transplant recipients receiving induction therapy. Int J Dermatol 2008; 47: 918-925
24. Opelz G, Döhler B. Lymphomas after solid organ transplantation: a collaborative transplant study report. Am J Transplant 2004; 4: 222-230.