메뉴 건너뛰기




Volumn 9, Issue 3, 2013, Pages 285-290

Recognizing Hospitalized Heart Failure as an Entity and Developing New Therapies to Improve Outcomes. Academics', Clinicians', Industry's, Regulators', and Payers' Perspectives.

Author keywords

Heart failure; Hospitalized heart failure; Postdischarge mortality

Indexed keywords

ROLOFYLLINE;

EID: 84879699020     PISSN: 15517136     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.hfc.2013.05.002     Document Type: Review
Times cited : (38)

References (41)
  • 1
    • 77955893501 scopus 로고    scopus 로고
    • Long-term survival of cancer patients compared to heart failure and stroke: a systematic review
    • Askoxylakis V., Thieke C., Pleger S.T., et al. Long-term survival of cancer patients compared to heart failure and stroke: a systematic review. BMC Cancer 2010, 10:105.
    • (2010) BMC Cancer , vol.10 , pp. 105
    • Askoxylakis, V.1    Thieke, C.2    Pleger, S.T.3
  • 2
    • 79952444246 scopus 로고    scopus 로고
    • Forecasting the future of cardiovascular disease in the United States: a policy statement from the American Heart Association
    • Heidenreich P.A., Trogdon J.G., Khavjou O.A., et al. Forecasting the future of cardiovascular disease in the United States: a policy statement from the American Heart Association. Circulation 2011, 123:933-944.
    • (2011) Circulation , vol.123 , pp. 933-944
    • Heidenreich, P.A.1    Trogdon, J.G.2    Khavjou, O.A.3
  • 3
    • 84855353573 scopus 로고    scopus 로고
    • Heart disease and stroke statistics-2012 update: a report from the American Heart Association
    • Roger V.L., Go A.S., Lloyd-Jones D.M., et al. Heart disease and stroke statistics-2012 update: a report from the American Heart Association. Circulation 2012, 125:e2-e220.
    • (2012) Circulation , vol.125
    • Roger, V.L.1    Go, A.S.2    Lloyd-Jones, D.M.3
  • 4
    • 80054739874 scopus 로고    scopus 로고
    • National andregional trends in heart failure hospitalization and mortality rates for Medicare beneficiaries, 1998-2008
    • Chen J., Normand S.L., Wang Y., et al. National andregional trends in heart failure hospitalization and mortality rates for Medicare beneficiaries, 1998-2008. JAMA 2011, 306:1669-1678.
    • (2011) JAMA , vol.306 , pp. 1669-1678
    • Chen, J.1    Normand, S.L.2    Wang, Y.3
  • 5
    • 33750731595 scopus 로고    scopus 로고
    • Systolic blood pressure at admission, clinical characteristics, and outcomes in patients hospitalized with acute heart failure
    • Gheorghiade M., Abraham W.T., Albert N.M., et al. Systolic blood pressure at admission, clinical characteristics, and outcomes in patients hospitalized with acute heart failure. JAMA 2006, 296:2217-2226.
    • (2006) JAMA , vol.296 , pp. 2217-2226
    • Gheorghiade, M.1    Abraham, W.T.2    Albert, N.M.3
  • 6
    • 68949094510 scopus 로고    scopus 로고
    • Heart failure performance measures and outcomes: real or illusory gains
    • Fonarow G.C., Peterson E.D. Heart failure performance measures and outcomes: real or illusory gains. JAMA 2009, 302:792-794.
    • (2009) JAMA , vol.302 , pp. 792-794
    • Fonarow, G.C.1    Peterson, E.D.2
  • 7
    • 84855179168 scopus 로고    scopus 로고
    • The relationship between hospital admission rates and rehospitalizations
    • Epstein A.M., Jha A.K., Orav E.J. The relationship between hospital admission rates and rehospitalizations. NEngl J Med 2011, 365:2287-2295.
    • (2011) NEngl J Med , vol.365 , pp. 2287-2295
    • Epstein, A.M.1    Jha, A.K.2    Orav, E.J.3
  • 8
    • 34447539951 scopus 로고    scopus 로고
    • Repeated hospitalizations predict mortality in the community population with heart failure
    • Setoguchi S., Stevenson L.W., Schneeweiss S. Repeated hospitalizations predict mortality in the community population with heart failure. Am Heart J 2007, 154:260-266.
    • (2007) Am Heart J , vol.154 , pp. 260-266
    • Setoguchi, S.1    Stevenson, L.W.2    Schneeweiss, S.3
  • 9
    • 83455172647 scopus 로고    scopus 로고
    • Factors associated with improvement in ejection fraction in clinical practice among patients with heart failure: findings from IMPROVE HF
    • Wilcox J.E., Fonarow G.C., Yancy C.W., et al. Factors associated with improvement in ejection fraction in clinical practice among patients with heart failure: findings from IMPROVE HF. Am Heart J 2012, 163:49-56.e2.
    • (2012) Am Heart J , vol.163
    • Wilcox, J.E.1    Fonarow, G.C.2    Yancy, C.W.3
  • 10
    • 79551582915 scopus 로고    scopus 로고
    • Hospital readmission as an accountability measure
    • Axon R.N., Williams M.V. Hospital readmission as an accountability measure. JAMA 2011, 305:504-505.
    • (2011) JAMA , vol.305 , pp. 504-505
    • Axon, R.N.1    Williams, M.V.2
  • 11
    • 84865258582 scopus 로고    scopus 로고
    • Resource utilization and costs following hospitalization of patients with chronic heart failure in the US
    • Korves C., Eldar-Lissai A., McHale J., et al. Resource utilization and costs following hospitalization of patients with chronic heart failure in the US. JMed Econ 2012, 15:925-937.
    • (2012) JMed Econ , vol.15 , pp. 925-937
    • Korves, C.1    Eldar-Lissai, A.2    McHale, J.3
  • 12
    • 84876337749 scopus 로고    scopus 로고
    • Strategies and opportunities for drug development in heart failure
    • Butler J., Fonarow G.C., Gheorghiade M. Strategies and opportunities for drug development in heart failure. JAMA 2013, 309:1593-1594.
    • (2013) JAMA , vol.309 , pp. 1593-1594
    • Butler, J.1    Fonarow, G.C.2    Gheorghiade, M.3
  • 13
    • 79851511096 scopus 로고    scopus 로고
    • Clinical development of pharmacologic agents for acute heart failure syndromes: a proposal for a mechanistic translational phase
    • Gheorghiade M., Pang P.S., O'Connor C.M., et al. Clinical development of pharmacologic agents for acute heart failure syndromes: a proposal for a mechanistic translational phase. Am Heart J 2011, 161:224-232.
    • (2011) Am Heart J , vol.161 , pp. 224-232
    • Gheorghiade, M.1    Pang, P.S.2    O'Connor, C.M.3
  • 14
  • 15
    • 0034859710 scopus 로고    scopus 로고
    • Renal effects of adenosine A1-receptor antagonists in congestive heart failure
    • Gottlieb S.S. Renal effects of adenosine A1-receptor antagonists in congestive heart failure. Drugs 2001, 61:1387-1393.
    • (2001) Drugs , vol.61 , pp. 1387-1393
    • Gottlieb, S.S.1
  • 16
    • 0037133628 scopus 로고    scopus 로고
    • BG9719 (CVT-124), an A1 adenosine receptor antagonist, protects against the decline in renal function observed with diuretic therapy
    • Gottlieb S.S., Brater D.C., Thomas I., et al. BG9719 (CVT-124), an A1 adenosine receptor antagonist, protects against the decline in renal function observed with diuretic therapy. Circulation 2002, 105:1348-1353.
    • (2002) Circulation , vol.105 , pp. 1348-1353
    • Gottlieb, S.S.1    Brater, D.C.2    Thomas, I.3
  • 17
    • 0033955058 scopus 로고    scopus 로고
    • Effects of BG9719 (CVT-124), an A1-adenosine receptor antagonist, and furosemide on glomerular filtration rate and natriuresis in patients with congestive heart failure
    • Gottlieb S.S., Skettino S.L., Wolff A., et al. Effects of BG9719 (CVT-124), an A1-adenosine receptor antagonist, and furosemide on glomerular filtration rate and natriuresis in patients with congestive heart failure. JAm Coll Cardiol 2000, 35:56-59.
    • (2000) JAm Coll Cardiol , vol.35 , pp. 56-59
    • Gottlieb, S.S.1    Skettino, S.L.2    Wolff, A.3
  • 18
    • 77957730950 scopus 로고    scopus 로고
    • Rolofylline, an adenosine A1-receptor antagonist, in acute heart failure
    • Massie B.M., O'Connor C.M., Metra M., et al. Rolofylline, an adenosine A1-receptor antagonist, in acute heart failure. NEngl J Med 2010, 363:1419-1428.
    • (2010) NEngl J Med , vol.363 , pp. 1419-1428
    • Massie, B.M.1    O'Connor, C.M.2    Metra, M.3
  • 19
    • 0036023204 scopus 로고    scopus 로고
    • The prognostic importance of different definitions of worsening renal function in congestive heart failure
    • Gottlieb S.S., Abraham W., Butler J., et al. The prognostic importance of different definitions of worsening renal function in congestive heart failure. JCard Fail 2002, 8:136-141.
    • (2002) JCard Fail , vol.8 , pp. 136-141
    • Gottlieb, S.S.1    Abraham, W.2    Butler, J.3
  • 20
    • 77957984258 scopus 로고    scopus 로고
    • Long-term benefit of primary prevention with an implantable cardioverter-defibrillator: an extended 8-year follow-up study of the Multicenter Automatic Defibrillator Implantation Trial II
    • Goldenberg I., Gillespie J., Moss A.J., et al. Long-term benefit of primary prevention with an implantable cardioverter-defibrillator: an extended 8-year follow-up study of the Multicenter Automatic Defibrillator Implantation Trial II. Circulation 2010, 122:1265-1271.
    • (2010) Circulation , vol.122 , pp. 1265-1271
    • Goldenberg, I.1    Gillespie, J.2    Moss, A.J.3
  • 21
    • 77950485827 scopus 로고    scopus 로고
    • The impact of early standard therapy on dyspnoea in patients with acute heart failure: the URGENT-dyspnoea study
    • Mebazaa A., Pang P.S., Tavares M., et al. The impact of early standard therapy on dyspnoea in patients with acute heart failure: the URGENT-dyspnoea study. Eur Heart J 2010, 31:832-841.
    • (2010) Eur Heart J , vol.31 , pp. 832-841
    • Mebazaa, A.1    Pang, P.S.2    Tavares, M.3
  • 22
    • 0037329098 scopus 로고    scopus 로고
    • Dyspnea as an end point in clinical trials of therapies for acute decompensated heart failure
    • Teerlink J.R. Dyspnea as an end point in clinical trials of therapies for acute decompensated heart failure. Am Heart J 2003, 145:S26-S33.
    • (2003) Am Heart J , vol.145
    • Teerlink, J.R.1
  • 23
    • 77955436904 scopus 로고    scopus 로고
    • Areview of dyspnea in acute heart failure syndromes
    • West R.L., Hernandez A.F., O'Connor C.M., et al. Areview of dyspnea in acute heart failure syndromes. Am Heart J 2010, 160:209-214.
    • (2010) Am Heart J , vol.160 , pp. 209-214
    • West, R.L.1    Hernandez, A.F.2    O'Connor, C.M.3
  • 24
    • 41149148032 scopus 로고    scopus 로고
    • Aproposal to standardize dyspnoea measurement in clinical trials of acute heart failure syndromes: the need for a uniform approach
    • Pang P.S., Cleland J.G., Teerlink J.R., et al. Aproposal to standardize dyspnoea measurement in clinical trials of acute heart failure syndromes: the need for a uniform approach. Eur Heart J 2008, 29:816-824.
    • (2008) Eur Heart J , vol.29 , pp. 816-824
    • Pang, P.S.1    Cleland, J.G.2    Teerlink, J.R.3
  • 25
    • 77958606969 scopus 로고    scopus 로고
    • International variations in the clinical, diagnostic, and treatment characteristics of emergency department patients with acute heart failure syndromes
    • Collins S.P., Pang P.S., Lindsell C.J., et al. International variations in the clinical, diagnostic, and treatment characteristics of emergency department patients with acute heart failure syndromes. Eur J Heart Fail 2010, 12:1253-1260.
    • (2010) Eur J Heart Fail , vol.12 , pp. 1253-1260
    • Collins, S.P.1    Pang, P.S.2    Lindsell, C.J.3
  • 26
    • 33947713810 scopus 로고    scopus 로고
    • Effects of oral tolvaptan in patients hospitalized for worsening heart failure: the EVEREST Outcome Trial
    • Konstam M.A., Gheorghiade M., Burnett J.C., et al. Effects of oral tolvaptan in patients hospitalized for worsening heart failure: the EVEREST Outcome Trial. JAMA 2007, 297:1319-1331.
    • (2007) JAMA , vol.297 , pp. 1319-1331
    • Konstam, M.A.1    Gheorghiade, M.2    Burnett, J.C.3
  • 27
    • 33947719178 scopus 로고    scopus 로고
    • Short-term clinical effects of tolvaptan, an oral vasopressin antagonist, in patients hospitalized for heart failure: the EVEREST Clinical Status Trials
    • Gheorghiade M., Konstam M.A., Burnett J.C., et al. Short-term clinical effects of tolvaptan, an oral vasopressin antagonist, in patients hospitalized for heart failure: the EVEREST Clinical Status Trials. JAMA 2007, 297:1332-1343.
    • (2007) JAMA , vol.297 , pp. 1332-1343
    • Gheorghiade, M.1    Konstam, M.A.2    Burnett, J.C.3
  • 28
    • 67049117504 scopus 로고    scopus 로고
    • PhaseIII clinical trial end points in acute heart failure syndromes: a virtual roundtable with the Acute Heart Failure Syndromes International Working Group
    • Gheorghiade M., Adams K.F., Cleland J.G., et al. PhaseIII clinical trial end points in acute heart failure syndromes: a virtual roundtable with the Acute Heart Failure Syndromes International Working Group. Am Heart J 2009, 157:957-970.
    • (2009) Am Heart J , vol.157 , pp. 957-970
    • Gheorghiade, M.1    Adams, K.F.2    Cleland, J.G.3
  • 29
    • 33644878033 scopus 로고    scopus 로고
    • Acute heart failure syndromes: current state and framework for future research
    • Gheorghiade M., Zannad F., Sopko G., et al. Acute heart failure syndromes: current state and framework for future research. Circulation 2005, 112:3958-3968.
    • (2005) Circulation , vol.112 , pp. 3958-3968
    • Gheorghiade, M.1    Zannad, F.2    Sopko, G.3
  • 30
    • 0037181511 scopus 로고    scopus 로고
    • Intravenous nesiritide vs nitroglycerin for treatment of decompensated congestive heart failure: a randomized controlled trial
    • Publication Committee for the VMAC Investigators (Vasodilatation in the Management of Acute CHF)
    • Publication Committee for the VMAC Investigators (Vasodilatation in the Management of Acute CHF) Intravenous nesiritide vs nitroglycerin for treatment of decompensated congestive heart failure: a randomized controlled trial. JAMA 2002, 287:1531-1540.
    • (2002) JAMA , vol.287 , pp. 1531-1540
  • 31
    • 0037181515 scopus 로고    scopus 로고
    • Short-term intravenous milrinone for acute exacerbation of chronic heart failure: a randomized controlled trial
    • Cuffe M.S., Califf R.M., Adams K.F., et al. Short-term intravenous milrinone for acute exacerbation of chronic heart failure: a randomized controlled trial. JAMA 2002, 287:1541-1547.
    • (2002) JAMA , vol.287 , pp. 1541-1547
    • Cuffe, M.S.1    Califf, R.M.2    Adams, K.F.3
  • 32
    • 35848944656 scopus 로고    scopus 로고
    • Effects of tezosentan on symptoms and clinical outcomes in patients with acute heart failure: the VERITAS randomized controlled trials
    • McMurray J.J., Teerlink J.R., Cotter G., et al. Effects of tezosentan on symptoms and clinical outcomes in patients with acute heart failure: the VERITAS randomized controlled trials. JAMA 2007, 298:2009-2019.
    • (2007) JAMA , vol.298 , pp. 2009-2019
    • McMurray, J.J.1    Teerlink, J.R.2    Cotter, G.3
  • 33
    • 34247857479 scopus 로고    scopus 로고
    • Levosimendan vs. dobutamine for patients with acute decompensated heart failure: the SURVIVE Randomized Trial
    • Mebazaa A., Nieminen M.S., Packer M., et al. Levosimendan vs. dobutamine for patients with acute decompensated heart failure: the SURVIVE Randomized Trial. JAMA 2007, 297:1883-1891.
    • (2007) JAMA , vol.297 , pp. 1883-1891
    • Mebazaa, A.1    Nieminen, M.S.2    Packer, M.3
  • 34
    • 79960090547 scopus 로고    scopus 로고
    • Effect of nesiritide in patients with acute decompensated heart failure
    • O'Connor C.M., Starling R.C., Hernandez A.F., et al. Effect of nesiritide in patients with acute decompensated heart failure. NEngl J Med 2011, 365:32-43.
    • (2011) NEngl J Med , vol.365 , pp. 32-43
    • O'Connor, C.M.1    Starling, R.C.2    Hernandez, A.F.3
  • 35
    • 84864687000 scopus 로고    scopus 로고
    • Bayesian adaptive trial design in acute heart failure syndromes: moving beyond the mega trial
    • Collins S.P., Lindsell C.J., Pang P.S., et al. Bayesian adaptive trial design in acute heart failure syndromes: moving beyond the mega trial. Am Heart J 2012, 164:138-145.
    • (2012) Am Heart J , vol.164 , pp. 138-145
    • Collins, S.P.1    Lindsell, C.J.2    Pang, P.S.3
  • 36
    • 55049127403 scopus 로고    scopus 로고
    • Continental differences in clinical characteristics, management, and outcomes in patients hospitalized with worsening heart failure results from the EVEREST (Efficacy of Vasopressin Antagonism in Heart Failure: Outcome Study with Tolvaptan) program
    • Blair J.E., Zannad F., Konstam M.A., et al. Continental differences in clinical characteristics, management, and outcomes in patients hospitalized with worsening heart failure results from the EVEREST (Efficacy of Vasopressin Antagonism in Heart Failure: Outcome Study with Tolvaptan) program. JAm Coll Cardiol 2008, 52:1640-1648.
    • (2008) JAm Coll Cardiol , vol.52 , pp. 1640-1648
    • Blair, J.E.1    Zannad, F.2    Konstam, M.A.3
  • 37
    • 84855708993 scopus 로고    scopus 로고
    • Patient characteristics from a regional multicenter database of acute decompensated heart failure in Asia Pacific (ADHERE International-Asia Pacific)
    • Atherton J.J., Hayward C.S., Wan Ahmad W.A., et al. Patient characteristics from a regional multicenter database of acute decompensated heart failure in Asia Pacific (ADHERE International-Asia Pacific). JCard Fail 2012, 18:82-88.
    • (2012) JCard Fail , vol.18 , pp. 82-88
    • Atherton, J.J.1    Hayward, C.S.2    Wan Ahmad, W.A.3
  • 38
    • 84894556346 scopus 로고    scopus 로고
    • Site selection in global clinical trials in patients hospitalized for heart failure: perceived problems and potential solutions
    • [Epub ahead of print]
    • Gheorghiade M., Vaduganathan M., Greene S.J., et al. Site selection in global clinical trials in patients hospitalized for heart failure: perceived problems and potential solutions. Heart Fail Rev 2012, [Epub ahead of print].
    • (2012) Heart Fail Rev
    • Gheorghiade, M.1    Vaduganathan, M.2    Greene, S.J.3
  • 39
    • 84873095762 scopus 로고    scopus 로고
    • Relationship between clinical trial site enrollment with participant characteristics, protocol completion, and outcomes: insights from the EVEREST (Efficacy of Vasopressin Antagonism in Heart Failure: Outcome Study with Tolvaptan) Trial
    • Butler J., Subacius H., Vaduganathan M., et al. Relationship between clinical trial site enrollment with participant characteristics, protocol completion, and outcomes: insights from the EVEREST (Efficacy of Vasopressin Antagonism in Heart Failure: Outcome Study with Tolvaptan) Trial. JAm Coll Cardiol 2013, 61(5):571-579.
    • (2013) JAm Coll Cardiol , vol.61 , Issue.5 , pp. 571-579
    • Butler, J.1    Subacius, H.2    Vaduganathan, M.3
  • 40
    • 77953635924 scopus 로고    scopus 로고
    • Prediction modeling using EHR data: challenges, strategies, and a comparison of machine learning approaches
    • 21
    • Wu J., Roy J., Stewart W.F. Prediction modeling using EHR data: challenges, strategies, and a comparison of machine learning approaches. Med Care 2010, 48:S106-S113. 21.
    • (2010) Med Care , vol.48
    • Wu, J.1    Roy, J.2    Stewart, W.F.3
  • 41
    • 84879723243 scopus 로고    scopus 로고
    • Drug makers join efforts in research. The New York Times, September 19, 2012. Available at: Accessed December 13
    • Pollack A. Drug makers join efforts in research. The New York Times, September 19, 2012. Available at: Accessed December 13, 2012. http://www.nytimes.com/2012/09/20/health/drug-makers-in-joint-effort-to-streamlineresearch.
    • (2012)
    • Pollack, A.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.