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Volumn 14, Issue 2, 2013, Pages 113-118

Pathophysiology of GHRH-growth hormone-IGF1 axis in HIV/AIDS

Author keywords

AIDS wasting syndrome GH; GHRH; HIV; Lipodystrophy; Tesamorelin

Indexed keywords

C REACTIVE PROTEIN; GHRELIN; GROWTH HORMONE RELEASING FACTOR; INTERLEUKIN 6; PRAVASTATIN; ROSIGLITAZONE; SOMATOMEDIN C; SOMATOSTATIN; TESAMORELIN;

EID: 84879689483     PISSN: 13899155     EISSN: 15732606     Source Type: Journal    
DOI: 10.1007/s11154-013-9245-9     Document Type: Article
Times cited : (17)

References (53)
  • 1
    • 60749110770 scopus 로고    scopus 로고
    • Hypopituitarism and HIV-infection: A new comorbidity in the HAART era?
    • 1:STN:280:DC%2BD1cfgtVKnsA%3D%3D
    • Zirilli L, Orlando G, Diazzi C, et al. Hypopituitarism and HIV-infection: a new comorbidity in the HAART era? J Endocrinol Investig. 2008;31:33-8.
    • (2008) J Endocrinol Investig , vol.31 , pp. 33-38
    • Zirilli, L.1    Orlando, G.2    Diazzi, C.3
  • 2
    • 0042131994 scopus 로고    scopus 로고
    • HIV lipodystrophy: Prevalence, severity and correlates of risk in Australia
    • 12859330 10.1046/j.1468-1293.2003.00159.x 1:STN:280: DC%2BD3szotVahsw%3D%3D
    • Miller J, Carr A, Emery S, et al. HIV lipodystrophy: prevalence, severity and correlates of risk in Australia. HIV Med. 2003;4:293-301.
    • (2003) HIV Med , vol.4 , pp. 293-301
    • Miller, J.1    Carr, A.2    Emery, S.3
  • 3
    • 36048952049 scopus 로고    scopus 로고
    • Metabolic function and the prevalence of lipodystrophy in a population of HIV-infected African subjects receiving highly active antiretroviral therapy
    • 18077834 10.1097/QAI.0b013e318158c0a6 1:CAS:528:DC%2BD2sXht1yms73I
    • Mutimura E, Stewart A, Rheeder P, Crowther NJ. Metabolic function and the prevalence of lipodystrophy in a population of HIV-infected African subjects receiving highly active antiretroviral therapy. J Acquir Immune Defic Syndr. 2007;46:451-5.
    • (2007) J Acquir Immune Defic Syndr , vol.46 , pp. 451-455
    • Mutimura, E.1    Stewart, A.2    Rheeder, P.3    Crowther, N.J.4
  • 4
    • 44049092911 scopus 로고    scopus 로고
    • Lipodystrophy in pediatric HIV
    • 18536889 10.1007/s12098-008-0037-2
    • Desai N, Mullen P, Mathur M. Lipodystrophy in pediatric HIV. Indian J Pediatr. 2008;75:351-4.
    • (2008) Indian J Pediatr , vol.75 , pp. 351-354
    • Desai, N.1    Mullen, P.2    Mathur, M.3
  • 5
    • 0033305699 scopus 로고    scopus 로고
    • Fasting hyperinsulinemia and changes in regional body composition in human immunodeficiency virus-infected women
    • 10372689 10.1210/jc.84.6.1932 1:CAS:528:DyaK1MXjs1Oiu7w%3D
    • Hadigan C, Miller K, Corcoran C, Anderson E, Basgoz N, Grinspoon S. Fasting hyperinsulinemia and changes in regional body composition in human immunodeficiency virus-infected women. J Clin Endocrinol Metab. 1999;84:1932-7.
    • (1999) J Clin Endocrinol Metab , vol.84 , pp. 1932-1937
    • Hadigan, C.1    Miller, K.2    Corcoran, C.3    Anderson, E.4    Basgoz, N.5    Grinspoon, S.6
  • 6
    • 0034457359 scopus 로고    scopus 로고
    • Fasting hyperinsulinemia in human immunodeficiency virus-infected men: Relationship to body composition, gonadal function, and protease inhibitor use
    • 10634360 10.1210/jc.85.1.35 1:CAS:528:DC%2BD3cXjtl2isA%3D%3D
    • Hadigan C, Corcoran C, Stanley T, Piecuch S, Klibanski A, Grinspoon S. Fasting hyperinsulinemia in human immunodeficiency virus-infected men: relationship to body composition, gonadal function, and protease inhibitor use. J Clin Endocrinol Metab. 2000;85:35-41.
    • (2000) J Clin Endocrinol Metab , vol.85 , pp. 35-41
    • Hadigan, C.1    Corcoran, C.2    Stanley, T.3    Piecuch, S.4    Klibanski, A.5    Grinspoon, S.6
  • 7
    • 0035134609 scopus 로고    scopus 로고
    • Metabolic abnormalities and cardiovascular disease risk factors in adults with human immunodeficiency virus infection and lipodystrophy
    • 10.1086/317541 1:STN:280:DC%2BD3M7jt1Kntw%3D%3D
    • Hadigan C, Meigs JB, Corcoran C, et al. Metabolic abnormalities and cardiovascular disease risk factors in adults with human immunodeficiency virus infection and lipodystrophy. Clin Infect Dis Off Publ Infect Dis Soc Am. 2001;32:130-9.
    • (2001) Clin Infect Dis off Publ Infect Dis Soc Am , vol.32 , pp. 130-139
    • Hadigan, C.1    Meigs, J.B.2    Corcoran, C.3
  • 8
    • 0036182863 scopus 로고    scopus 로고
    • Elevated concentrations of free fatty acids are associated with increased insulin response to standard glucose challenge in human immunodeficiency virus-infected subjects with fat redistribution
    • 11833059 10.1053/meta.2002.29999 1:CAS:528:DC%2BD38Xht1WgtbY%3D
    • Meininger G, Hadigan C, Laposata M, et al. Elevated concentrations of free fatty acids are associated with increased insulin response to standard glucose challenge in human immunodeficiency virus-infected subjects with fat redistribution. Metab Clin Exp. 2002;51:260-6.
    • (2002) Metab Clin Exp , vol.51 , pp. 260-266
    • Meininger, G.1    Hadigan, C.2    Laposata, M.3
  • 9
    • 0942287339 scopus 로고    scopus 로고
    • Metabolic regulation of growth hormone by free fatty acids, somatostatin, and ghrelin in HIV-lipodystrophy
    • 14559725 10.1152/ajpendo.00335.2003 1:CAS:528:DC%2BD2cXhsFartro%3D
    • Koutkia P, Meininger G, Canavan B, Breu J, Grinspoon S. Metabolic regulation of growth hormone by free fatty acids, somatostatin, and ghrelin in HIV-lipodystrophy. Am J Physiol Endocrinol Metab. 2004;286:E296-303.
    • (2004) Am J Physiol Endocrinol Metab , vol.286 , pp. 296-303
    • Koutkia, P.1    Meininger, G.2    Canavan, B.3    Breu, J.4    Grinspoon, S.5
  • 10
    • 18144389038 scopus 로고    scopus 로고
    • Increased cardiovascular disease risk indices in HIV-infected women
    • 15851913 10.1097/01.qai.0000159323.59250.83
    • Dolan SE, Hadigan C, Killilea KM, et al. Increased cardiovascular disease risk indices in HIV-infected women. J Acquir Immune Defic Syndr. 2005;39:44-54.
    • (2005) J Acquir Immune Defic Syndr , vol.39 , pp. 44-54
    • Dolan, S.E.1    Hadigan, C.2    Killilea, K.M.3
  • 11
    • 33744527559 scopus 로고    scopus 로고
    • HIV-infected patients with lipodystrophy have higher rates of carotid atherosclerosis: The role of monocyte chemoattractant protein-1
    • 16697654 10.1016/j.cyto.2006.03.013 1:CAS:528:DC%2BD28XltlKnt70%3D
    • Coll B, Parra S, Alonso-Villaverde C, et al. HIV-infected patients with lipodystrophy have higher rates of carotid atherosclerosis: the role of monocyte chemoattractant protein-1. Cytokine. 2006;34:51-5.
    • (2006) Cytokine , vol.34 , pp. 51-55
    • Coll, B.1    Parra, S.2    Alonso-Villaverde, C.3
  • 12
    • 0032461188 scopus 로고    scopus 로고
    • Effects of androgen administration on the growth hormone-insulin-like growth factor i axis in men with acquired immunodeficiency syndrome wasting
    • 9851759 10.1210/jc.83.12.4251 1:CAS:528:DyaK1cXnvFOrtrY%3D
    • Grinspoon S, Corcoran C, Stanley T, Katznelson L, Klibanski A. Effects of androgen administration on the growth hormone-insulin-like growth factor I axis in men with acquired immunodeficiency syndrome wasting. J Clin Endocrinol Metab. 1998;83:4251-6.
    • (1998) J Clin Endocrinol Metab , vol.83 , pp. 4251-4256
    • Grinspoon, S.1    Corcoran, C.2    Stanley, T.3    Katznelson, L.4    Klibanski, A.5
  • 13
    • 0035090230 scopus 로고    scopus 로고
    • Assessment of growth hormone dynamics in human immunodeficiency virus-related lipodystrophy
    • 11158000 10.1210/jc.86.2.504 1:CAS:528:DC%2BD3MXht1Kns7s%3D
    • Rietschel P, Hadigan C, Corcoran C, et al. Assessment of growth hormone dynamics in human immunodeficiency virus-related lipodystrophy. J Clin Endocrinol Metab. 2001;86:504-10.
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 504-510
    • Rietschel, P.1    Hadigan, C.2    Corcoran, C.3
  • 14
    • 0029847997 scopus 로고    scopus 로고
    • Circadian growth hormone secretion in asymptomatic human immune deficiency virus infection and acquired immunodeficiency syndrome
    • 8923855 10.1210/jc.81.11.4028 1:CAS:528:DyaK28XntVCrsLw%3D
    • Heijligenberg R, Sauerwein HP, Brabant G, Endert E, Hommes MJ, Romijn JA. Circadian growth hormone secretion in asymptomatic human immune deficiency virus infection and acquired immunodeficiency syndrome. J Clin Endocrinol Metab. 1996;81:4028-32.
    • (1996) J Clin Endocrinol Metab , vol.81 , pp. 4028-4032
    • Heijligenberg, R.1    Sauerwein, H.P.2    Brabant, G.3    Endert, E.4    Hommes, M.J.5    Romijn, J.A.6
  • 15
    • 11344256743 scopus 로고    scopus 로고
    • Different growth hormone sensitivity of target tissues and growth hormone response to glucose in HIV-infected patients with and without lipodystrophy
    • 15764170 10.1080/00365540410021162 1:CAS:528:DC%2BD2MXkvVan
    • Andersen O, Haugaard SB, Hansen BR, et al. Different growth hormone sensitivity of target tissues and growth hormone response to glucose in HIV-infected patients with and without lipodystrophy. Scand J Infect Dis. 2004;36:832-9.
    • (2004) Scand J Infect Dis , vol.36 , pp. 832-839
    • Andersen, O.1    Haugaard, S.B.2    Hansen, B.R.3
  • 16
    • 0029934235 scopus 로고    scopus 로고
    • Wasting in the acquired immune deficiency syndrome is associated with multiple defects in the serum insulin-like growth factor system
    • 10.1046/j.1365-2265.1996.705526.x 1:STN:280:DyaK28zgsleitg%3D%3D
    • Frost RA, Fuhrer J, Steigbigel R, Mariuz P, Lang CH, Gelato MC. Wasting in the acquired immune deficiency syndrome is associated with multiple defects in the serum insulin-like growth factor system. Clin Endocrinol. 1996;44:501-14.
    • (1996) Clin Endocrinol , vol.44 , pp. 501-514
    • Frost, R.A.1    Fuhrer, J.2    Steigbigel, R.3    Mariuz, P.4    Lang, C.H.5    Gelato, M.C.6
  • 17
    • 0030779626 scopus 로고    scopus 로고
    • Responsiveness of muscle protein synthesis to growth hormone administration in HIV-infected individuals declines with severity of disease
    • 9329979 10.1172/JCI119747 1:CAS:528:DyaK2sXmslKku7o%3D
    • McNurlan MA, Garlick PJ, Steigbigel RT, et al. Responsiveness of muscle protein synthesis to growth hormone administration in HIV-infected individuals declines with severity of disease. J Clin Invest. 1997;100:2125-32.
    • (1997) J Clin Invest , vol.100 , pp. 2125-2132
    • McNurlan, M.A.1    Garlick, P.J.2    Steigbigel, R.T.3
  • 18
    • 0030737928 scopus 로고    scopus 로고
    • Abdominal adiposity rather than age and sex predicts mass and regularity of GH secretion in healthy adults
    • 9227458 1:CAS:528:DyaK2sXktlOguro%3D
    • Vahl N, Jorgensen JO, Skjaerbaek C, Veldhuis JD, Orskov H, Christiansen JS. Abdominal adiposity rather than age and sex predicts mass and regularity of GH secretion in healthy adults. Am J Physiol. 1997;272:E1108-16.
    • (1997) Am J Physiol , vol.272 , pp. 1108-1116
    • Vahl, N.1    Jorgensen, J.O.2    Skjaerbaek, C.3    Veldhuis, J.D.4    Orskov, H.5    Christiansen, J.S.6
  • 19
    • 34347207985 scopus 로고    scopus 로고
    • Tripartite control of growth hormone secretion in women during controlled estradiol repletion
    • 17405836 10.1210/jc.2007-0043 1:CAS:528:DC%2BD2sXmslOgsLg%3D
    • Veldhuis JD, Cosma M, Erickson D, et al. Tripartite control of growth hormone secretion in women during controlled estradiol repletion. J Clin Endocrinol Metab. 2007;92:2336-45.
    • (2007) J Clin Endocrinol Metab , vol.92 , pp. 2336-2345
    • Veldhuis, J.D.1    Cosma, M.2    Erickson, D.3
  • 20
    • 0035181709 scopus 로고    scopus 로고
    • Altered neuroregulation of GH secretion in viscerally obese premenopausal women
    • 11701729 10.1210/jc.86.11.5509 1:CAS:528:DC%2BD3MXos1KqtLw%3D
    • Pijl H, Langendonk JG, Burggraaf J, et al. Altered neuroregulation of GH secretion in viscerally obese premenopausal women. J Clin Endocrinol Metab. 2001;86:5509-15.
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 5509-5515
    • Pijl, H.1    Langendonk, J.G.2    Burggraaf, J.3
  • 21
    • 0034887335 scopus 로고    scopus 로고
    • Abdominal visceral fat and fasting insulin are important predictors of 24-hour GH release independent of age, gender, and other physiological factors
    • 11502822 10.1210/jc.86.8.3845 1:CAS:528:DC%2BD3MXlvFeku78%3D
    • Clasey JL, Weltman A, Patrie J, et al. Abdominal visceral fat and fasting insulin are important predictors of 24-hour GH release independent of age, gender, and other physiological factors. J Clin Endocrinol Metab. 2001;86:3845-52.
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 3845-3852
    • Clasey, J.L.1    Weltman, A.2    Patrie, J.3
  • 22
    • 0025962290 scopus 로고
    • Evidence for a direct pituitary inhibition by free fatty acids of in vivo growth hormone responses to growth hormone-releasing hormone in the rat
    • 1673023 10.1159/000125716 1:CAS:528:DyaK3MXhtFGgtrg%3D
    • Alvarez CV, Mallo F, Burguera B, Cacicedo L, Dieguez C, Casanueva FF. Evidence for a direct pituitary inhibition by free fatty acids of in vivo growth hormone responses to growth hormone-releasing hormone in the rat. Neuroendocrinology. 1991;53:185-9.
    • (1991) Neuroendocrinology , vol.53 , pp. 185-189
    • Alvarez, C.V.1    Mallo, F.2    Burguera, B.3    Cacicedo, L.4    Dieguez, C.5    Casanueva, F.F.6
  • 23
    • 0013672903 scopus 로고    scopus 로고
    • Cis-FFA do not alter membrane depolarization but block Ca2+ influx and GH secretion in KCl-stimulated somatotroph cells. Suggestion for a direct cis-FFA perturbation of the Ca2+ channel opening
    • 9371418 10.1016/S0005-2736(97)00111-9 1:CAS:528:DyaK2sXmtVWht7w%3D
    • Perez FR, Camina JP, Zugaza JL, Lage M, Casabiell X, Casanueva FF. cis-FFA do not alter membrane depolarization but block Ca2+ influx and GH secretion in KCl-stimulated somatotroph cells. Suggestion for a direct cis-FFA perturbation of the Ca2+ channel opening. Biochim Biophys Acta. 1997;1329:269-77.
    • (1997) Biochim Biophys Acta , vol.1329 , pp. 269-277
    • Perez, F.R.1    Camina, J.P.2    Zugaza, J.L.3    Lage, M.4    Casabiell, X.5    Casanueva, F.F.6
  • 24
    • 51749084593 scopus 로고    scopus 로고
    • Treatment of altered body composition in HIV-associated lipodystrophy: Comparison of rosiglitazone, pravastatin, and recombinant human growth hormone
    • 18753120 10.1310/hct0904-254
    • Macallan DC, Baldwin C, Mandalia S, et al. Treatment of altered body composition in HIV-associated lipodystrophy: comparison of rosiglitazone, pravastatin, and recombinant human growth hormone. HIV Clin Trials. 2008;9:254-68.
    • (2008) HIV Clin Trials , vol.9 , pp. 254-268
    • Macallan, D.C.1    Baldwin, C.2    Mandalia, S.3
  • 25
    • 0037055028 scopus 로고    scopus 로고
    • Abacavir substitution for nucleoside analogs in patients with HIV lipoatrophy: A randomized trial
    • 12095385 10.1001/jama.288.2.207 1:CAS:528:DC%2BD38XltFGru7k%3D
    • Carr A, Workman C, Smith DE, et al. Abacavir substitution for nucleoside analogs in patients with HIV lipoatrophy: a randomized trial. JAMA. 2002;288:207-15.
    • (2002) JAMA , vol.288 , pp. 207-215
    • Carr, A.1    Workman, C.2    Smith, D.E.3
  • 26
    • 20644467776 scopus 로고    scopus 로고
    • Metabolic benefits 24 months after replacing a protease inhibitor with abacavir, efavirenz or nevirapine
    • 15905672 10.1097/01.aids.0000171405.46113.bf 1:CAS:528: DC%2BD2MXktlKlurw%3D
    • Fisac C, Fumero E, Crespo M, et al. Metabolic benefits 24 months after replacing a protease inhibitor with abacavir, efavirenz or nevirapine. AIDS. 2005;19:917-25.
    • (2005) AIDS , vol.19 , pp. 917-925
    • Fisac, C.1    Fumero, E.2    Crespo, M.3
  • 27
    • 33750227103 scopus 로고    scopus 로고
    • A randomized comparative trial of tenofovir DF or abacavir as replacement for a thymidine analogue in persons with lipoatrophy
    • 17053350 10.1097/01.aids.0000247574.33998.03 1:CAS:528:DC%2BD28XhtV2rsrnE
    • Moyle GJ, Sabin CA, Cartledge J, et al. A randomized comparative trial of tenofovir DF or abacavir as replacement for a thymidine analogue in persons with lipoatrophy. AIDS. 2006;20:2043-50.
    • (2006) AIDS , vol.20 , pp. 2043-2050
    • Moyle, G.J.1    Sabin, C.A.2    Cartledge, J.3
  • 28
    • 64649106435 scopus 로고    scopus 로고
    • Peripheral and visceral fat changes following a treatment switch to a non-thymidine analogue or a nucleoside-sparing regimen in HIV-infected subjects with peripheral lipoatrophy: Results of ACTG A5110
    • 19299471 10.1093/jac/dkp071 1:CAS:528:DC%2BD1MXksVaqu7g%3D
    • Tebas P, Zhang J, Hafner R, et al. Peripheral and visceral fat changes following a treatment switch to a non-thymidine analogue or a nucleoside-sparing regimen in HIV-infected subjects with peripheral lipoatrophy: results of ACTG A5110. J Antimicrob Chemother. 2009;63:998-1005.
    • (2009) J Antimicrob Chemother , vol.63 , pp. 998-1005
    • Tebas, P.1    Zhang, J.2    Hafner, R.3
  • 30
    • 0042869786 scopus 로고    scopus 로고
    • Serum adipocytokines are related to lipodystrophy and metabolic disorders in HIV-infected men under antiretroviral therapy
    • 12824788 10.1097/00002030-200307040-00011 1:CAS:528:DC%2BD3sXlt1Whtr8%3D
    • Vigouroux C, Maachi M, Nguyen TH, et al. Serum adipocytokines are related to lipodystrophy and metabolic disorders in HIV-infected men under antiretroviral therapy. AIDS. 2003;17:1503-11.
    • (2003) AIDS , vol.17 , pp. 1503-1511
    • Vigouroux, C.1    Maachi, M.2    Nguyen, T.H.3
  • 31
    • 0942265682 scopus 로고    scopus 로고
    • Increased systemic and adipose tissue cytokines in patients with HIV-associated lipodystrophy
    • 14532165 10.1152/ajpendo.00056.2003 1:CAS:528:DC%2BD2cXhsFartr4%3D
    • Johnson JA, Albu JB, Engelson ES, et al. Increased systemic and adipose tissue cytokines in patients with HIV-associated lipodystrophy. Am J Physiol Endocrinol Metab. 2004;286:E261-71.
    • (2004) Am J Physiol Endocrinol Metab , vol.286 , pp. 261-271
    • Johnson, J.A.1    Albu, J.B.2    Engelson, E.S.3
  • 32
    • 0037161026 scopus 로고    scopus 로고
    • Association between altered expression of adipogenic factor SREBP1 in lipoatrophic adipose tissue from HIV-1-infected patients and abnormal adipocyte differentiation and insulin resistance
    • 11937183 10.1016/S0140-6736(02)08094-7 1:CAS:528:DC%2BD38XisV2htrs%3D
    • Bastard JP, Caron M, Vidal H, et al. Association between altered expression of adipogenic factor SREBP1 in lipoatrophic adipose tissue from HIV-1-infected patients and abnormal adipocyte differentiation and insulin resistance. Lancet. 2002;359:1026-31.
    • (2002) Lancet , vol.359 , pp. 1026-1031
    • Bastard, J.P.1    Caron, M.2    Vidal, H.3
  • 33
    • 9244219676 scopus 로고    scopus 로고
    • Role of mitochondria in HIV lipoatrophy: Insight into pathogenesis and potential therapies
    • 16120376 10.1016/j.mito.2004.05.008 1:CAS:528:DC%2BD2cXnvFWmurc%3D
    • McComsey GA, Walker UA. Role of mitochondria in HIV lipoatrophy: insight into pathogenesis and potential therapies. Mitochondrion. 2004;4:111-8.
    • (2004) Mitochondrion , vol.4 , pp. 111-118
    • McComsey, G.A.1    Walker, U.A.2
  • 34
    • 2342441342 scopus 로고    scopus 로고
    • Adipocytes targets and actors in the pathogenesis of HIV-associated lipodystrophy and metabolic alterations
    • 15134178 1:CAS:528:DC%2BD2cXltFyhsrk%3D
    • Gougeon ML, Penicaud L, Fromenty B, Leclercq P, Viard JP, Capeau J. Adipocytes targets and actors in the pathogenesis of HIV-associated lipodystrophy and metabolic alterations. Antivir Ther. 2004;9:161-77.
    • (2004) Antivir Ther , vol.9 , pp. 161-177
    • Gougeon, M.L.1    Penicaud, L.2    Fromenty, B.3    Leclercq, P.4    Viard, J.P.5    Capeau, J.6
  • 35
    • 77956562598 scopus 로고    scopus 로고
    • Effects of insulin-like growth factor (IGF)-I/IGF-binding protein-3 treatment on glucose metabolism and fat distribution in human immunodeficiency virus-infected patients with abdominal obesity and insulin resistance
    • 20610601 10.1210/jc.2009-2502 1:CAS:528:DC%2BC3cXht1Wms73L
    • Rao MN, Mulligan K, Tai V, et al. Effects of insulin-like growth factor (IGF)-I/IGF-binding protein-3 treatment on glucose metabolism and fat distribution in human immunodeficiency virus-infected patients with abdominal obesity and insulin resistance. J Clin Endocrinol Metab. 2010;95:4361-6.
    • (2010) J Clin Endocrinol Metab , vol.95 , pp. 4361-4366
    • Rao, M.N.1    Mulligan, K.2    Tai, V.3
  • 36
    • 12244251427 scopus 로고    scopus 로고
    • Growth hormone (GH) responses to GH-releasing hormone-arginine testing in human immunodeficiency virus lipodystrophy
    • 15483073 10.1210/jc.2004-1342 1:CAS:528:DC%2BD2MXlvFentQ%3D%3D
    • Koutkia P, Canavan B, Breu J, Grinspoon S. Growth hormone (GH) responses to GH-releasing hormone-arginine testing in human immunodeficiency virus lipodystrophy. J Clin Endocrinol Metab. 2005;90:32-8.
    • (2005) J Clin Endocrinol Metab , vol.90 , pp. 32-38
    • Koutkia, P.1    Canavan, B.2    Breu, J.3    Grinspoon, S.4
  • 37
    • 0034886796 scopus 로고    scopus 로고
    • The effects of recombinant human growth hormone on body composition and glucose metabolism in HIV-infected patients with fat accumulation
    • 11502767 10.1210/jc.86.8.3480 1:CAS:528:DC%2BD3MXlvFeksb0%3D
    • Lo JC, Mulligan K, Noor MA, et al. The effects of recombinant human growth hormone on body composition and glucose metabolism in HIV-infected patients with fat accumulation. J Clin Endocrinol Metab. 2001;86:3480-7.
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 3480-3487
    • Lo, J.C.1    Mulligan, K.2    Noor, M.A.3
  • 38
    • 33750381449 scopus 로고    scopus 로고
    • Drug evaluation: Tesamorelin, a synthetic human growth hormone releasing factor
    • 17086939 1:CAS:528:DC%2BD28Xht1eitbfM
    • Tomlinson B. Drug evaluation: tesamorelin, a synthetic human growth hormone releasing factor. Curr Opin Investig Drugs. 2006;7:936-45.
    • (2006) Curr Opin Investig Drugs , vol.7 , pp. 936-945
    • Tomlinson, B.1
  • 39
    • 67449093468 scopus 로고    scopus 로고
    • Tesamorelin, a human growth hormone releasing factor analogue
    • 19243281 10.1517/13543780802707658 1:CAS:528:DC%2BD1MXitlWrtrs%3D
    • Wang Y, Tomlinson B. Tesamorelin, a human growth hormone releasing factor analogue. Expert Opin Investig Drugs. 2009;18:303-10.
    • (2009) Expert Opin Investig Drugs , vol.18 , pp. 303-310
    • Wang, Y.1    Tomlinson, B.2
  • 40
    • 33846009834 scopus 로고    scopus 로고
    • Non-clinical pharmacology and safety evaluation of TH9507, a human growth hormone-releasing factor analogue
    • 17214611 10.1111/j.1742-7843.2007.00008.x 1:CAS:528:DC%2BD2sXivVOrsrg%3D
    • Ferdinandi ES, Brazeau P, High K, Procter B, Fennell S, Dubreuil P. Non-clinical pharmacology and safety evaluation of TH9507, a human growth hormone-releasing factor analogue. Basic Clin Pharmacol Toxicol. 2007;100:49-58.
    • (2007) Basic Clin Pharmacol Toxicol , vol.100 , pp. 49-58
    • Ferdinandi, E.S.1    Brazeau, P.2    High, K.3    Procter, B.4    Fennell, S.5    Dubreuil, P.6
  • 41
    • 36849058739 scopus 로고    scopus 로고
    • Metabolic effects of a growth hormone-releasing factor in patients with HIV
    • 18057338 10.1056/NEJMoa072375 1:CAS:528:DC%2BD2sXhsVWhtrvF
    • Falutz J, Allas S, Blot K, et al. Metabolic effects of a growth hormone-releasing factor in patients with HIV. N Engl J Med. 2007;357:2359-70.
    • (2007) N Engl J Med , vol.357 , pp. 2359-2370
    • Falutz, J.1    Allas, S.2    Blot, K.3
  • 42
    • 77649226509 scopus 로고    scopus 로고
    • Effects of tesamorelin, a growth hormone-releasing factor, in HIV-infected patients with abdominal fat accumulation: A randomized placebo-controlled trial with a safety extension
    • 20101189 10.1097/QAI.0b013e3181cbdaff 1:CAS:528:DC%2BC3cXisFejur4%3D
    • Falutz J, Potvin D, Mamputu JC, et al. Effects of tesamorelin, a growth hormone-releasing factor, in HIV-infected patients with abdominal fat accumulation: a randomized placebo-controlled trial with a safety extension. J Acquir Immune Defic Syndr. 2010;53:311-22.
    • (2010) J Acquir Immune Defic Syndr , vol.53 , pp. 311-322
    • Falutz, J.1    Potvin, D.2    Mamputu, J.C.3
  • 43
    • 84861069214 scopus 로고    scopus 로고
    • Reduction in visceral adiposity is associated with an improved metabolic profile in HIV-infected patients receiving tesamorelin
    • 10.1093/cid/cis251 1:CAS:528:DC%2BC38Xnt1egtrc%3D
    • Stanley TL, Falutz J, Marsolais C, et al. Reduction in visceral adiposity is associated with an improved metabolic profile in HIV-infected patients receiving tesamorelin. Clin Infect Dis Off Publ Infect Dis Soc Am. 2012;54:1642-51.
    • (2012) Clin Infect Dis off Publ Infect Dis Soc Am , vol.54 , pp. 1642-1651
    • Stanley, T.L.1    Falutz, J.2    Marsolais, C.3
  • 44
    • 0037111579 scopus 로고    scopus 로고
    • Switching effective antiretroviral therapy: A review
    • 10.1086/343050 1:CAS:528:DC%2BD3sXhtlKgsbg%3D
    • Drechsler H, Powderly WG. Switching effective antiretroviral therapy: a review. Clin Infect Dis Off Publ Infect Dis Soc Am. 2002;35:1219-30.
    • (2002) Clin Infect Dis off Publ Infect Dis Soc Am , vol.35 , pp. 1219-1230
    • Drechsler, H.1    Powderly, W.G.2
  • 45
    • 0034456220 scopus 로고    scopus 로고
    • Impact of switching from human immunodeficiency virus type 1 protease inhibitors to efavirenz in successfully treated adults with lipodystrophy
    • 10.1086/317426 1:CAS:528:DC%2BD3MXhsVKgsw%3D%3D
    • Martinez E, Garcia-Viejo MA, Blanco JL, et al. Impact of switching from human immunodeficiency virus type 1 protease inhibitors to efavirenz in successfully treated adults with lipodystrophy. Clin Infect Dis Off Publ Infect Dis Soc Am. 2000;31:1266-73.
    • (2000) Clin Infect Dis off Publ Infect Dis Soc Am , vol.31 , pp. 1266-1273
    • Martinez, E.1    Garcia-Viejo, M.A.2    Blanco, J.L.3
  • 46
    • 0035393524 scopus 로고    scopus 로고
    • Antiretroviral treatment simplification with nevirapine in protease inhibitor-experienced patients with hiv-associated lipodystrophy: 1-year prospective follow-up of a multicenter, randomized, controlled study
    • 11464141 1:CAS:528:DC%2BD3MXlslamsbs%3D
    • Ruiz L, Negredo E, Domingo P, et al. Antiretroviral treatment simplification with nevirapine in protease inhibitor-experienced patients with hiv-associated lipodystrophy: 1-year prospective follow-up of a multicenter, randomized, controlled study. J Acquir Immune Defic Syndr. 2001;27:229-36.
    • (2001) J Acquir Immune Defic Syndr , vol.27 , pp. 229-236
    • Ruiz, L.1    Negredo, E.2    Domingo, P.3
  • 47
    • 0035964696 scopus 로고    scopus 로고
    • HIV protease inhibitor substitution in patients with lipodystrophy: A randomized, controlled, open-label, multicentre study
    • 11579243 10.1097/00002030-200109280-00010 1:CAS:528:DC%2BD3MXnvVantrY%3D
    • Carr A, Hudson J, Chuah J, et al. HIV protease inhibitor substitution in patients with lipodystrophy: a randomized, controlled, open-label, multicentre study. AIDS. 2001;15:1811-22.
    • (2001) AIDS , vol.15 , pp. 1811-1822
    • Carr, A.1    Hudson, J.2    Chuah, J.3
  • 48
    • 1642456562 scopus 로고    scopus 로고
    • Improvement in lipoatrophy associated with highly active antiretroviral therapy in human immunodeficiency virus-infected patients switched from stavudine to abacavir or zidovudine: The results of the TARHEEL study
    • 10.1086/380790 1:CAS:528:DC%2BD2cXhtFSgu74%3D
    • McComsey GA, Ward DJ, Hessenthaler SM, et al. Improvement in lipoatrophy associated with highly active antiretroviral therapy in human immunodeficiency virus-infected patients switched from stavudine to abacavir or zidovudine: the results of the TARHEEL study. Clin Infect Dis Off Publ Infect Dis Soc Am. 2004;38:263-70.
    • (2004) Clin Infect Dis off Publ Infect Dis Soc Am , vol.38 , pp. 263-270
    • McComsey, G.A.1    Ward, D.J.2    Hessenthaler, S.M.3
  • 49
    • 33847126560 scopus 로고    scopus 로고
    • Less lipoatrophy and better lipid profile with abacavir as compared to stavudine: 96-week results of a randomized study
    • 17106274 10.1097/QAI.0b013e31802bf122 1:CAS:528:DC%2BD2sXitVehu74%3D
    • Podzamczer D, Ferrer E, Sanchez P, et al. Less lipoatrophy and better lipid profile with abacavir as compared to stavudine: 96-week results of a randomized study. J Acquir Immune Defic Syndr. 2007;44:139-47.
    • (2007) J Acquir Immune Defic Syndr , vol.44 , pp. 139-147
    • Podzamczer, D.1    Ferrer, E.2    Sanchez, P.3
  • 50
    • 37349062681 scopus 로고    scopus 로고
    • The safety and efficacy of switching stavudine to tenofovir df in combination with lamivudine and efavirenz in hiv-1-infected patients: Three-year follow-up after switching therapy
    • 18042503 10.1310/hct0806-381
    • Madruga JR, Cassetti I, Suleiman JM, et al. The safety and efficacy of switching stavudine to tenofovir df in combination with lamivudine and efavirenz in hiv-1-infected patients: three-year follow-up after switching therapy. HIV Clin Trials. 2007;8:381-90.
    • (2007) HIV Clin Trials , vol.8 , pp. 381-390
    • Madruga, J.R.1    Cassetti, I.2    Suleiman, J.M.3
  • 51
    • 0042387870 scopus 로고    scopus 로고
    • Substitution of nevirapine, efavirenz, or abacavir for protease inhibitors in patients with human immunodeficiency virus infection
    • 12968087 10.1056/NEJMoa021589 1:CAS:528:DC%2BD3sXntlagur4%3D
    • Martinez E, Arnaiz JA, Podzamczer D, et al. Substitution of nevirapine, efavirenz, or abacavir for protease inhibitors in patients with human immunodeficiency virus infection. N Engl J Med. 2003;349:1036-46.
    • (2003) N Engl J Med , vol.349 , pp. 1036-1046
    • Martinez, E.1    Arnaiz, J.A.2    Podzamczer, D.3
  • 52
    • 17144407574 scopus 로고    scopus 로고
    • Growth of human immunodeficiency virus-infected children receiving highly active antiretroviral therapy
    • 15818296 10.1097/01.inf.0000157095.75081.43
    • Nachman SA, Lindsey JC, Moye J, et al. Growth of human immunodeficiency virus-infected children receiving highly active antiretroviral therapy. Pediatr Infect Dis J. 2005;24:352-7.
    • (2005) Pediatr Infect Dis J , vol.24 , pp. 352-357
    • Nachman, S.A.1    Lindsey, J.C.2    Moye, J.3
  • 53
    • 0036479949 scopus 로고    scopus 로고
    • Treatment with highly active antiretroviral therapy in human immunodeficiency virus type 1-infected children is associated with a sustained effect on growth
    • 11826235 10.1542/peds.109.2.e25
    • Verweel G, van Rossum AM, Hartwig NG, Wolfs TF, Scherpbier HJ, de Groot R. Treatment with highly active antiretroviral therapy in human immunodeficiency virus type 1-infected children is associated with a sustained effect on growth. Pediatrics. 2002;109:E25.
    • (2002) Pediatrics , vol.109 , pp. 25
    • Verweel, G.1    Van Rossum, A.M.2    Hartwig, N.G.3    Wolfs, T.F.4    Scherpbier, H.J.5    De Groot, R.6


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