A soft coral natural product, 11-episinulariolide acetate, inhibits gene expression of cyclooxygenase-2 and interleukin-8 through attenuation of calcium signaling

Molecules

Volumn 18, Issue 6, 2013, Pages 7023-7034

  Hsu, Wen Li ^a,b   Chiu, Siou Jin ^a   Tsai, Yao Ting ^a   Chang, Che Mai ^a   Wang, Jaw Yan ^b,c   Wang, Eric Terry ^a   Hou, Ming Feng ^b,c   Huang, Chiung Yao ^c,d   Sheu, Jyh Horng ^d,e,f   Chang, Wei Chiao ^a,c  

^a TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^b KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

^c KAOHSIUNG MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^d NATIONAL SUN YAT SEN UNIVERSITY   (Taiwan)

^e KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

^f CHINA MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

Calcium; COX 2; EGF; IL 8; Marine compound

Indexed keywords

BIOLOGICAL PRODUCT; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITOR; DITERPENE; EPIDERMAL GROWTH FACTOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 8; SINULARIOLIDE; TRANSCRIPTION FACTOR NFAT;

ANIMAL; ANTHOZOA; CALCIUM SIGNALING; CELL LINE; CHEMISTRY; DOSE RESPONSE; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; HUMAN; METABOLISM; SIGNAL TRANSDUCTION; ARTICLE; DRUG EFFECT;

ANIMALS; ANTHOZOA; BIOLOGICAL PRODUCTS; CALCIUM SIGNALING; CELL LINE; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITORS; DITERPENES; DOSE-RESPONSE RELATIONSHIP, DRUG; EPIDERMAL GROWTH FACTOR; GENE EXPRESSION REGULATION; HUMANS; INTERLEUKIN-8; NF-KAPPA B; NFATC TRANSCRIPTION FACTORS; SIGNAL TRANSDUCTION;

EID: 84879668630     PISSN: None     EISSN: 14203049     Source Type: Journal    
DOI: 10.3390/molecules18067023     Document Type: Article

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