Methanolic extract of white asparagus shoots activates TRAIL apoptotic death pathway in human cancer cells and inhibits colon carcinogenesis in a preclinical model

International Journal of Oncology

Volumn 43, Issue 2, 2013, Pages 394-404

  Bousserouel, Souad ^a,b   Le Grandois, Julie ^c   Gossé, Francine ^a,b   Werner, Dalal ^c   Barth, Stephan W ^d   Marchioni, Eric ^a   Marescaux, Jacques ^b   Raul, Francis ^a,b  

^a UNIVERSITÉ DE STRASBOURG   (France)

^b IRCAD   (France)

^c AERIAL   (France)

^d FEDERAL RESEARCH INSTITUTE OF NUTRITION AND FOOD   (Germany)

Author keywords

Aberrant crypt foci; Asparagus officinalis; Caspases; Colorectal cancer; Death receptors; Inflammation; SW480 cells; SW620 cells

Indexed keywords

ANTINEOPLASTIC AGENT; CASPASE 3; CASPASE 8; DEATH RECEPTOR 4; DEATH RECEPTOR 5; GELATINASE B; INTERLEUKIN 1BETA; MATRILYSIN; MESSENGER RNA; PLANT EXTRACT; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; UNCLASSIFIED DRUG; WHITE ASPARAGUS EXTRACT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; ASPARAGUS; CANCER INHIBITION; CARCINOMA CELL; CELL CULTURE; CELL DEATH; CELL PROLIFERATION; CELL SURFACE; CELLULAR DISTRIBUTION; CHEMOPROPHYLAXIS; COLON ADENOCARCINOMA; COLON CARCINOGENESIS; COLON CARCINOMA; COLON MUCOSA; CONTROLLED STUDY; DRUG EFFICACY; FLOW CYTOMETRY; HOST RESISTANCE; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SHOOT; WHITE ASPARAGUS;

ANIMALS; ANTICARCINOGENIC AGENTS; APOPTOSIS; ASPARAGUS PLANT; AZOXYMETHANE; CARCINOGENESIS; CASPASE 3; CASPASE 8; CELL LINE, TUMOR; CELL PROLIFERATION; COLONIC NEOPLASMS; ENZYME ACTIVATION; HUMANS; INTESTINAL MUCOSA; MALE; METHANOL; PLANT EXTRACTS; PLANT SHOOTS; RATS; RATS, WISTAR; TNF-RELATED APOPTOSIS-INDUCING LIGAND;

EID: 84879664923     PISSN: 10196439     EISSN: 17912423     Source Type: Journal    
DOI: 10.3892/ijo.2013.1976     Document Type: Article

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