Expression of KISS1 and KISS1R (GPR54) may be used as favorable prognostic markers for patients with non-small cell lung cancer

International Journal of Oncology

Volumn 43, Issue 2, 2013, Pages 521-530

  Sun, Yan Bin ^a   Xu, Shun ^a  

^a CHINA MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

G PROTEIN COUPLED RECEPTOR 54; LIPOCORTIN 5; METASTIN;

ADULT; APOPTOSIS; ARTICLE; CANCER PROGNOSIS; CANCER STAGING; CANCER SURVIVAL; CELL DIFFERENTIATION; CPG ISLAND; FEMALE; HUMAN; LUNG NON SMALL CELL CANCER; MAJOR CLINICAL STUDY; MALE; METHYLATION; OVERALL SURVIVAL; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; SURVIVAL RATE;

CARCINOMA, NON-SMALL-CELL LUNG; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, TUMOR SUPPRESSOR; HUMANS; KAPLAN-MEIER ESTIMATE; KISSPEPTINS; LUNG NEOPLASMS; MALE; MIDDLE AGED; NEOPLASM METASTASIS; NEOPLASM STAGING; PROPORTIONAL HAZARDS MODELS; RECEPTORS, G-PROTEIN-COUPLED; SURVIVAL RATE; TUMOR SUPPRESSOR PROTEINS;

EID: 84879650193     PISSN: 10196439     EISSN: 17912423     Source Type: Journal    
DOI: 10.3892/ijo.2013.1967     Document Type: Article

References (39)

1. Jemal A, Bray F, Center MM, et al: Global cancer statistics. CA Cancer J Clin 61: 69-90, 2011.
2. Bray FI and Weiderpass E: Lung cancer mortality trends in 36 European countries: secular trends and birth cohort patterns by sex and region 1970-2007. Int J Cancer 126: 1454-1466, 2010.
3. Lam WK, White NW and Chan-Yeung MM: Lung cancer epidemiology and risk factors in Asia and Africa. Int J Tuberc Lung Dis 8: 1045-1057, 2004. (Pubitemid 39201249)
4. Youlden DR, Cramb SM and Baade PD: The International Epidemiology of Lung Cancer: geographical distribution and secular trends. J Thorac Oncol 3: 819-831, 2008.
5. Herbst RS, Heymach JV and Lippman SM: Lung cancer. N Engl J Med 359: 1367-1380, 2008.
6. Soon YY, Stockler MR, Askie LM, et al: Duration of chemo therapy for advanced non-small cell lung cancer: a systematic review and meta-analysis of randomized trials. J Clin Oncol 27: 3277-3283, 2009.
7. Lee JH, Miele ME, Hicks DJ, et al: KiSS-1, a novel human malignant melanoma metastasis-suppressor gene. J Natl Cancer Inst 88: 1731-1737, 1996. (Pubitemid 26405010)
8. Makri A, Pissimissis N, Lembessis P, et al: The kisspeptin (KISS-1)/GPR54 system in cancer biology. Cancer Treat Rev 34: 682-692, 2008.
9. Masui T, Doi R, Mori T, et al: Metastin and its variant forms suppress migration of pancreatic cancer cells. Biochem Biophys Res Commun 315: 85-92, 2004. (Pubitemid 38175189)
10. Martin TA, Watkins G and Jiang WG: KiSS-1 expression in human breast cancer. Clin Exp Metastasis 22: 503-511, 2005. (Pubitemid 41750702)
11. Nicolle G, Comperat E, Nicolaïew N, et al: Metastin (KISS-1) and metastin-coupled receptor (GPR54) expression in transi tional cell carcinoma of the bladder. Ann Oncol 18: 605-606, 2007.
12. Zohrabian VM, Nandu H, Gulati N, et al: Gene expression profiling of metastatic brain cancer. Oncol Rep 18: 321-328, 2007.
13. Hata K, Dhar DK, Watanabe Y, et al: Expression of metastin and a G-protein-coupled receptor (AXOR12) in epithelial ovarian cancer. Eur J Cancer 43: 1452-1459, 2007. (Pubitemid 46874063)
14. Yamashita S, Tsujino Y, Moriguchi K, et al: Chemical genomic screening for methylation-silenced genes in gastric cancer cell lines using 5-aza-2'-deoxycytidine treatment and oligonucle otide microarray. Cancer Sci 97: 64-71, 2006. (Pubitemid 43257029)
15. Seminara SB, Messager S, Chatzidaki EE, et al: The GPR54 gene as a regulator of puberty. N Engl J Med 349: 1614-1627, 2003. (Pubitemid 37303886)
16. De Roux N, Genin E, Carel JC, et al: Hypogonadotropic hypo gonadism due to loss of function of the KiSS1-derived peptide receptor GPR54. Proc Natl Acad Sci U S A 100: 10972-10976, 2003. (Pubitemid 37140137)
17. Ohtaki T, Shintani Y, Honda S, et al: Metastasis suppressor gene KiSS-1 encodes peptide ligand of a G-protein-coupled receptor. Nature 411: 613-617, 2001. (Pubitemid 32531412)
18. Stafford LJ, Xia C, Ma W, et al: Identification and characterization of mouse metastasis-suppressor KiSS1 and its G-protein coupled receptor. Cancer Res 62: 5399-5404, 2002.
19. Mitchell DC, Stafford LJ, Li D, et al: Transcriptional regula tion of KiSS-1 gene expression in metastatic melanoma by specificity protein -1 and its coactivator DRIP-130. Oncogene 26: 1739-1747, 2007. (Pubitemid 46426193)
20. Mead EJ, Maguire JJ, Kuc RE, et al: Kisspeptins: a multifunctional peptide system with a role in reproduction, cancer and the cardiovascular system. Br J Pharmacol 151: 1143-1153, 2007. (Pubitemid 47255895)
21. Ikeguchi M, Hirooka Y and Kaibara N: Quantitative reverse transcriptase polymerase chain reaction analysis for KiSS-1 and orphan G-protein-coupled receptor (hOT7T175) gene expres sion in hepatocellular carcinoma. J Cancer Res Clin Oncol 129: 531-535, 2003. (Pubitemid 37211194)
22. Zhang SL, Yu Y, Jiang T, et al: Expression and significance of KiSS-1 and its receptor GPR54 mRNA in epithelial ovarian cancer. Zhonghua Fu Chan Ke Za Zhi 40: 689-692, 2005 (In Chinese).
23. Tanoue LT and Detterbeck FC: New TNM classification for non-small-cell lung cancer. Expert Rev Anticancer Ther 9: 413-423, 2009.
24. Katagiri F, Tomita K, Oishi S, et al: Establishment and clinical application of enzyme immunoassays for determination of luteinizing hormone releasing hormone and metastin. J Pept Sci 13: 422-429, 2007. (Pubitemid 46902009)
25. Lee JH and Welch DR: Identification of highly expressed genes in metastasis-suppressed chromosome 6/human malignant melanoma hybrid cells using subtractive hybridization and differential display. Int J Cancer 71: 1035-1044, 1997.
26. Ikeguchi M, Yamaguchi K and Kaibara N: Clinical significance of the loss of KiSS-1 and orphan G-protein-coupled receptor (hOT7T175) gene expression in esophageal squamous cell carcinoma. Clin Cancer Res 10: 1379-1383, 2004. (Pubitemid 38365232)
27. Dhar DK, Naora H, Kubota H, et al : Downregulation of KiSS-1 expression is responsible for tumor invasion and worse prognosis in gastric carcinoma. Int J Cancer 111: 868-872, 2004. (Pubitemid 39096235)
28. Schmid K, Wang X, Haitel A, et al: KiSS-1 overexpression as an independent prognostic marker in hepatocellular carcinoma: an immunohistochemical study. Virchows Arch 450: 143-149, 2007. (Pubitemid 46295235)
29. Zheng S, Chang Y, Hodges KB, et al: Expression of KISS1 and MMP-9 in non-small cell lung cancer and their relations to metastasis and survival. Anticancer Res 30: 713-718, 2010.
30. Karapanagiotou EM, Dilana KD, Gkiozos I, et al: Metastin is not involved in metastatic potential of non-small cell lung cancer. Med Oncol 28: 559-564, 2011.
31. Cebrian V, Fierro M, Orenes-Piñero E, et al: KISS1 methylation and expression as tumor stratification biomarkers and clinical outcome prognosticators for bladder cancer patients. Am J Pathol 179: 540-546, 2011.
32. Moya P, Esteban S, Fernandez-Suarez A, et al: KiSS-1 meth ylation and protein expression patterns contribute to diagnostic and prognostic assessments in tissue specimens for colorectal cancer. Tumour Biol 34: 471-479, 2013.
33. Muir AI, Chamberlain L, Elshourbagy NA, et al: AXOR12, a novel human G protein-coupled receptor, activated by the peptide KiSS-1. J Biol Chem 276: 28969-28975, 2001.
34. Kotani M, Detheux M, Vandenbogaerde A, et al: The metas tasis suppressor gene KiSS-1 encodes kisspeptins, the natural ligands of the orphan G protein-coupled receptor GPR54. J Biol Chem 276: 34631-34636, 2001.
35. Jarza̧bek K, Kozłowski L, Milewski R, et al: KiSS1/GPR54 and estrogen-related gene expression profiles in primary breast cancer. Oncol Lett 3: 930-934, 2012.
36. Zajac M, Law J, Cvetkovic DD, et al: GPR54 (KISS1R) transac tivates EGFR to promote breast cancer cell invasiveness. PLoS One 6: e21599, 2011.
37. Niida A, Wang Z, Tomita K, et al: Design and synthesis of downsized metastin (45-54) analogs with maintenance of high GPR54 agonistic activity. Bioorg Med Chem Lett 16: 134-137, 2006. (Pubitemid 41625658)
38. Horikoshi Y, Matsumoto H, Takatsu Y, et al: Dramatic elevation of plasma metastin concentrations in human pregnancy: metastin as a novel placentaderived hormone in humans. J Clin Endocrinol Metab 88: 914-919, 2003. (Pubitemid 36207842)
39. Katagiri F, Nagai K, Kida A, et al: Clinical significance of plasma metastin level in pancreatic cancer patients. Oncol Rep 21: 815-819, 2009.