Non-24-hour disorder in blind individuals revisited: Variability and the influence of environmental time cues

Sleep

Volumn 36, Issue 7, 2013, Pages 1091-1100

  Emens, Jonathan S ^a   Laurie, Amber L ^a   Songer, Jeannie B ^a   Lewy, Alfred J ^a  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

Author keywords

Blind; Circadian; Melatonin; Non 24 h disorder

Indexed keywords

MELATONIN;

ACTIMETRY; ADULT; AGED; ARTICLE; ASSOCIATION; BLINDNESS; CHILD; CIRCADIAN RHYTHM; CLINICAL ARTICLE; CLINICAL ASSESSMENT; COORDINATION; ENVIRONMENTAL FACTOR; FEMALE; HEALTH CENTER; HORMONE BLOOD LEVEL; HUMAN; MALE; OBSERVATIONAL STUDY; OSCILLATION; PHYSICAL ACTIVITY; PLASMA; PRIORITY JOURNAL; RADIOIMMUNOASSAY; REST; SALIVA; SCHOOL CHILD; SLEEP WAKING CYCLE; WRIST;

EID: 84879646937     PISSN: 01618105     EISSN: 15509109     Source Type: Journal    
DOI: 10.5665/sleep.2818     Document Type: Article

References (47)

1. Lewy AJ, Newsome DA. Different types of melatonin circadian secretory rhythms in some blind subjects. J Clin Endocrinol Metab 1983;56:1103-7. (Pubitemid 13055100)
2. Sack RL, Lewy AJ, Blood ML, Keith LD, Nakagawa H. Circadian rhythm abnormalities in totally blind people: incidence and clinical significance. J Clin Endocrinol Metab 1992;75:127-34.
3. Klein T, Martens H, Dijk DJ, Kronauer RE, Seely EW, Czeisler CA. Circadian sleep regulation in the absence of light perception: chronic non- 24-hour circadian rhythm sleep disorder in a blind man with a regular 24-hour sleep-wake schedule. Sleep 1993;16:333-43. (Pubitemid 23176290)
4. Lockley SW, Skene DJ, Arendt J, Tabandeh H, Bird AC, Defrance R. Relationship between melatonin rhythms and visual loss in the blind. J Clin Endocrinol Metab 1997;82:3763-70. (Pubitemid 27509369)
5. Klerman EB, Rimmer DW, Dijk D, Kronauer RE, Rizzo III JF, Czeisler CA. Nonphotic entrainment of the human circadian pacemaker. Am J Physiol 1998;43:R991-6.
6. Lockley SW, Skene DJ, Butler LJ, Arendt J. Sleep and the activity rhythms are related to circadian phase in the blind. Sleep 1999;22:616-23. (Pubitemid 29379118)
7. Leger D, Guilleminault C, Defrance R, Domont A, Paillard M. Prevalence of sleep/wake disorders in persons with blindness. CliniSci 1999;97:193-9. (Pubitemid 29396624)
8. Sack RL, Brandes RW, Kendall AR, Lewy AJ. Entrainment of free-running circadian rhythms by melatonin in blind people. N Engl J Med 2000;343:1070-7.
9. Sack RL, Auckley D, Auger RR, et al. Circadian rhythm sleep disorders: part I, basic principles, shift work and jet lag disorders. Sleep 2007;30:1460-83. (Pubitemid 350036973)
10. Sack RL, Auckley D, Auger RR, et al. Circadian rhythm sleep disorders: part II, advanced sleep phase disorder, delayed sleep phase disorder, free-running disorder, and irregular sleep-wake rhythm. Sleep 2007;30:1484-501. (Pubitemid 350036974)
11. Lockley SW, Skene DJ, Butler LJ, Arendt J. Sleep and activity rhythms are related to circadian phase in the blind. Sleep 1999;22:616-23. (Pubitemid 29379118)
12. Leger D, Guilleminault C, Santos C, Paillard M. Sleep/wake cycles in the dark: sleep recorded by polysomnography in 26 totally blind subjects compared to controls. Clin Neurophysiol 2002;113:1607-14. (Pubitemid 35283948)
13. Emens J, Lewy AJ, Laurie AL, Songer JB. Rest-activity cycle and melatonin rhythm in blind free-runners have similar periods. J Biol Rhythms 2010;25:381-4.
14. Karatsoreos IN, Bhagat S, Bloss EB, Morrison JH, McEwen BS. Disruption of circadian clocks has ramifications for metabolism, brain, and behavior. Proc Natl Acad Sci U S A 2011;108:1657-62.
15. Scheer FAJL, Hilton MF, Mantzoros CS, Shea SA. Adverse metabolic and cardiovascular consequences of circadian misalignment. Proc Natl Acad Sci U S A 2009;106:4453-8.
16. Lockley SW, Skene DJ, James K, Thapan K, Wright J, Arendt J. Melatonin administration can entrain the free-running circadian system of blind subjects. J Endocrinol 2000;164:R1-6. (Pubitemid 30044335)
17. Lewy AJ, Bauer VK, Hasler BP, Kendall AR, Pires LN, Sack RL. Capturing the circadian rhythms of free-running blind people with 0.5 mg melatonin. Brain Res 2001;918:96-100. (Pubitemid 33001493)
18. Lewy AJ, Emens JS, Sack RL, Hasler BP, Bernert RA. Low, but not high, doses of melatonin entrained a free-running blind person with a long circadian period. Chronobiol Int 2002;19:649-58. (Pubitemid 34596531)
19. Hack LM, Lockley SW, Arendt J, Skene DJ. The effects of low-dose 0.5-mg melatonin on the free-running circadian rhythms of blind subjects. J Biol Rhythms 2003;18:420-9. (Pubitemid 37204464)
20. Lewy AJ, Emens JS, Bernert RA, Lefler BJ. Eventual entrainment of the human circadian pacemaker by melatonin is independent of the circadian phase of treatment initiation: clinical implications. J Biol Rhythms 2004;19:68-75. (Pubitemid 38084516)
21. Lewy AJ, Emens JS, Lefler BJ, Yuhas K, Jackman AR. Melatonin entrains free-running blind people according to a physiological dose-response curve. Chronobiol Int 2005;22:1093-106. (Pubitemid 43062253)
22. Emens JS, Lewy AJ, Lefler BJ, Sack RL. Relative coordination to unknown "weak zeitgebers" in free-running blind individuals. J Biol Rhythms 2005;20:159-67. (Pubitemid 40389162)
23. Wever RA. Light effects on human circadian rhythms. A review of recent Andechs experiments. J Biol Rhythms 1989;4:161-86.
24. Moore-Ede M, Sulzman FM, Fuller CA. The clocks that time us. Cambridge, MA: Harvard University Press, 1982.
25. Barger LK, Wright KP Jr, Hughes RJ, Czeisler CA. Daily exercise facilitates phase delays of circadian melatonin rhythm in very dim light. Am J Physiol Regul Integr Comp Physiol 2004;286:R1077-84. (Pubitemid 38661396)
26. Buxton OM, Lee CW, L'Hermite-Baleriaux M, Turek FW, Van Cauter E. Exercise elicits phase shifts and acute alterations of melatonin that vary with circadian phase. Am J Physiol Regul Integr Comp Physiol 2003;284:R714-24. (Pubitemid 36342804)
27. Klerman EB. Non-photic effects on the circadian system: results from experiments in blind and sighted individuals. In: Honma K, Honma S, eds. Zeitgebers, entrainment and masking of the circadian system. Sapporo: Hokkaido University Press, 2001:155-69.
28. Danilenko KV, Cajochen C, Wirz-Justice A. Is sleep per se a zeitgeber in humans? J Biol Rhythms 2003;18:170-8. (Pubitemid 37203372)
29. Gordijn M, Beersma D, Korte HJ, Van Den Hoofdakker RH. Effects of light exposure and sleep displacement on dim light melatonin onset. J Sleep Res 1999;8:163-74. (Pubitemid 29433607)
30. Hoban TM, Lewy AJ, Sack RL, Singer CM. The effects of shifting sleep two hours within a fixed photoperiod. J Neural Trans 1991;85:61-8.
31. Czeisler CA, Shanahan TL, Klerman EB, et al. Suppression of melatonin secretion in some blind patients by exposure to bright light. N Engl J Med 1995;332:6-11.
32. Klerman EB, Shanahan TL, Brotman DJ, et al. Photic Resetting of the Human Circadian Pacemaker in the Absence of Conscious Vision. J Biol Rhythms 2002;17:548-55. (Pubitemid 37187317)
33. Lewy AJ, Cutler NL, Sack RL. The endogenous melatonin profile as a marker for circadian phase position. J Biol Rhythms 1999;14:227-36. (Pubitemid 30157102)
34. Voultsios A, Kennaway DJ, Dawson D. Salivary melatonin as a circadian phase marker: validation and comparison to plasma melatonin. J Biol Rhythms 1997;12:457-66. (Pubitemid 127478560)
35. Emens JS, Yuhas K, Rough J, Kochar N, Peters D, Lewy AJ. Phase angle of entrainment in morning- and evening-types under naturalistic conditions. Chronobiol Int 2009;26:474-93.
36. Emens JS, Lewy AJ, Kinzie MJ, Arntz D, Rough J. Circadian misalignment in major depressive disorder. Psychiatry Res 2009;168:259-61.
37. Emens J, Lewy AJ, Rough JN, Songer JB. Sub-clinical dysphoria correlates with phase-delayed circadian misalignment in healthy individuals. Sleep 2009;32:A355.
38. Sokolove PG, Bushell WN. The chi square periodogram: its utility for analysis of circadian rhythms. J Theoret Biol 1978;72:131-60. (Pubitemid 8350595)
39. Kripke DF, Clopton P, Marler MR, Youngstedt SD, Elliot JA. PRC bisection tests. Chronobiol Int 2003;20:1117-23. (Pubitemid 37517521)
40. Kendall AR, Lewy AJ, Sack RL. Effects of aging on the intrinsic circadian period of totally blind humans. J Biol Rhythms 2001;16:87-95. (Pubitemid 32175309)
41. Campbell S. Is there an intrinsic period of the circadian clock? Science 2000;288:1174.
42. Czeisler CA, Dijk DJ, Kronauer RE, et al. Is there an intrinsic period of the circadian clock? Response. Science 2000;288:1174-5. (Pubitemid 30367178)
43. Duffy JF, Cain SW, Chang AM, et al. Sex difference in the near-24-hour intrinsic period of the human circadian timing system. Proc Natl Acad Sci 2011;108:15602-8.
44. Lewy A, Yuhas K, Emens J, et al. Are the circadian rhythms of blind adult males less sensitive to social cues than females? Sleep 2007;30A63.
45. Wright KP Jr, Gronfier C, Duffy JF, Czeisler CA. Intrinsic period and light intensity determine the phase relationship between melatonin and sleep in humans. J Biol Rhythms 2005;20:168-77. (Pubitemid 40389163)
46. Czeisler CA, Duffy JF, Shanahan TL, et al. Stability, precision and near-24-hour period of the human circadian pacemaker. Science 1999;284:2177-81. (Pubitemid 29297478)
47. Morin LP. Serotonin and the regulation of mammalian circadian rhythmicity. Ann Med 1999;31:12-33. (Pubitemid 29134482)