Substance P participates in immune-mediated hepatic injury induced by concanavalin A in mice and stimulates cytokine synthesis in Kupffer cells

Experimental and Therapeutic Medicine

Volumn 6, Issue 2, 2013, Pages 459-464

  Yang, Yan ^a   Yan, Ming ^a   Zhang, Haitao ^b   Wang, Xuping ^a  

^a SHANDONG UNIVERSITY   (China)

^b JINAN INFECTIOUS DISEASE HOSPITAL   (China)

Author keywords

Concanavalin A; Liver injury; Neurogenic inflammation; Neurokinin; Receptor antagonist; Substance P

Indexed keywords

2 BENZHYDRYL 3 (2 IODOBENZYLAMINO) QUINUCLIDINE; 2 BENZHYDRYL 3 (2 IODOBENZYLAMINO)QUINUCLIDINE; CONCANAVALIN A; INTERLEUKIN 6; LIVER ENZYME; MESSENGER RNA; NEUROKININ 1 RECEPTOR; SUBSTANCE P; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ACCLIMATIZATION; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL CELL; ANIMAL CELL CULTURE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; ENZYME LINKED IMMUNOSORBENT ASSAY; FLUORESCENCE MICROSCOPY; HISTOLOGY; IMMUNOFLUORESCENCE; IMMUNOREACTIVITY; IN VITRO STUDY; KUPFFER CELL; LIVER FUNCTION; LIVER HOMOGENATE; LIVER INJURY; LIVER NECROSIS; MALE; MOUSE; NONHUMAN; POLYMERASE CHAIN REACTION; PROTEIN EXPRESSION;

EID: 84879629368     PISSN: 17920981     EISSN: 17921015     Source Type: Journal    
DOI: 10.3892/etm.2013.1152     Document Type: Article

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