Building an evidence base in complementary and integrative healthcare for child and adolescent psychiatry

Child and Adolescent Psychiatric Clinics of North America

Volumn 22, Issue 3, 2013, Pages 509-529

  Edwards, Emmeline ^a   Mischoulon, David ^b   Rapaport, Mark ^c   Stussman, Barbara ^a   Weber, Wendy ^a  

^a NATIONAL INSTITUTES OF HEALTH   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

^c EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

CAM research; Child and adolescent psychiatry; Complementary medicine; Epidemiology; Integrative medicine; Manipulative therapies; Mind and body; Natural products

Indexed keywords

ANTICONVULSIVE AGENT; ANTIDEPRESSANT AGENT; ANXIOLYTIC AGENT; BELLADONNA ALKALOID; CANNABIS; CARNITINE; CENTRAL STIMULANT AGENT; CHAMOMILE; CITALOPRAM; GINKGO BILOBA EXTRACT; GINSENG EXTRACT; HALOPERIDOL; HYPERICUM PERFORATUM EXTRACT; KAVA; LAMOTRIGINE; LITHIUM SALT; MONOAMINE OXIDASE INHIBITOR; NATURAL PRODUCT; NEUROLEPTIC AGENT; OMEGA 3 FATTY ACID; PHENELZINE; PLACEBO; PROBIOTIC AGENT; PSYCHOTROPIC AGENT; PYCNOGENOL; SEROTONIN UPTAKE INHIBITOR; SERTRALINE; UNINDEXED DRUG; VALERIAN; VITAMIN;

ACUPUNCTURE; ALTERNATIVE MEDICINE; ANXIETY DISORDER; ATTENTION DEFICIT DISORDER; AUTISM; CHILD PSYCHIATRY; COGNITIVE THERAPY; DEMOGRAPHY; DEPRESSION; DISEASE SEVERITY; DRUG EFFICACY; DRUG SAFETY; EVIDENCE BASED MEDICINE; GYNECOMASTIA; HEALTH CARE POLICY; HOMEOPATHY; HUMAN; INSOMNIA; INTEGRATIVE MEDICINE; LIVER TOXICITY; MEDICAL RESEARCH; MEDITATION; MENTAL DISEASE; META ANALYSIS (TOPIC); METABOLIC SYNDROME X; PHOBIA; PREVALENCE; PRIORITY JOURNAL; PUBLIC HEALTH; RELAXATION TRAINING; REVIEW; SIDE EFFECT; SLEEP DISORDER; SUDDEN DEATH; SUICIDE; WEIGHT GAIN;

ADOLESCENT; ADOLESCENT PSYCHIATRY; CHILD; CHILD PSYCHIATRY; COMPLEMENTARY THERAPIES; EVIDENCE-BASED MEDICINE; HUMANS; INTEGRATIVE MEDICINE; MENTAL DISORDERS; TREATMENT OUTCOME;

EID: 84879605848     PISSN: 10564993     EISSN: 15580490     Source Type: Journal    
DOI: 10.1016/j.chc.2013.03.007     Document Type: Review

References (62)

1. NCCAM. Third Strategic Plan: 2011-2015. Exploring the science of complementary and alternative medicine. 2011. Available at: Accessed January 25, 2013. http://nccam.nih.gov/about/plans/2011.
2. NCCAM. What is Complementary and Alternative Medicine? 2008. Available at: Accessed January 25, 2013. http://nccam.nih.gov/health/whatiscam/.
3. Olfson M., Marcus S.C., Weissman M.M., et al. National trends in the use of psychotropic medications by children. JAm Acad Child Adolesc Psychiatry 2002, 41(5):514-521.
4. Zito J.M., Safer D.J., DosReis S., et al. Psychotropic practice patterns for youth: a 10-year perspective. Arch Pediatr Adolesc Med 2003, 157(1):17-25.
5. Maalouf F.T., Brent D.A. Child and adolescent depression intervention overview: what works, for whom and how well?. Child Adolesc Psychiatr Clin N Am 2012, 21(2):299-312.
6. Swanson J.M., Wigal T.L., Volkow N.D. Contrast of medical and nonmedical use of stimulant drugs, basis for the distinction, and risk of addiction: comment on Smith and Farah (2011). Psychol Bull 2011, 137(5):742-748.
7. Maayan L., Correll C.U. Weight gain and metabolic risks associated with antipsychotic medications in children and adolescents. JChild Adolesc Psychopharmacol 2011, 21(6):517-535. [review].
8. Westover A.N., Halm E.A. Do prescription stimulants increase the risk of adverse cardiovascular events?: a systematic review. BMC Cardiovasc Disord 2012, 12(1):41.
9. Osher T.W., Penn M., Spencer S.A. Partnerships with families for family-driven systems of care. The systems of care handbook: transforming mental health services for children, youth, and families 2008, Paul H. Brookes, New York, p. 249-73. B.A. Stroul, G.M. Blau (Eds.).
10. Davidson R.J., Kabat-Zinn J., Schumacher J., et al. Alterations in brain and immune function produced by mindfulness meditation. Psychosom Med 2003, 65(4):564-570.
11. Wall R.B. Tai Chi and mindfulness-based stress reduction in a Boston public middle school. JPediatr Health Care 2005, 19(4):230-237.
12. Freeman M.P., Mischoulon D., Tedeschini E., et al. Complementary and alternative medicine for major depressive disorder: a meta-analysis of patient characteristics, placebo-response rates, and treatment outcomes relative to standard antidepressants. JClin Psychiatry 2010, 71(6):682-688.
13. Deligiannidis K.M., Freeman M.P. Complementary and alternative medicine for the treatment of depressive disorders in women. Psychiatr Clin North Am 2010, 33(2):441-463.
14. Reynolds W.M., Coats K.I. Acomparison of cognitive-behavioral therapy and relaxation training for the treatment of depression in adolescents. JConsult Clin Psychol 1986, 54(5):653-660.
15. Murray L.L., Kim H.Y. Areview of select alternative treatment approaches for acquired neurogenic disorders: relaxation therapy and acupuncture. Semin Speech Lang 2004, 25(2):133-149.
16. Achenbach T.M., McConaughy S.H., Howell C.T. Child/adolescent behavioral and emotional problems: implications of cross-informant correlations for situational specificity. Psychol Bull 1987, 101(2):213-232.
17. Barnes P.M., Bloom B., Nahin R.L. Complementary and alternative medicine use among adults and children: United States, 2007. Natl Health Stat Report 2008, (12):1-23.
18. Birdee G.S., Phillips R.S., Davis R.B., et al. Factors associated with pediatric use of complementary and alternative medicine. Pediatrics 2010, 125(2):249-256.
19. Picciano M.F., Dwyer J.T., Radimer K.L., et al. Dietary supplement use among infants, children, and adolescents in the United States, 1999-2002. Arch Pediatr Adolesc Med 2007, 161(10):978-985.
20. Davis M.A., West A.N., Weeks W.B., et al. Health behaviors and utilization among users of complementary and alternative medicine for treatment versus health promotion. Health Serv Res 2011, 46(5):1402-1416.
21. Bloom B., Cohen R.A., Freeman G. Summary health statistics for U.S. children: National Health Interview Survey, 2010. Vital Health Stat 10 2011, (250):1-80.
22. Centers for Disease Control and Prevention (CDC) Mental health in the United States: parental report of diagnosed autism in children aged 4-17 years-United States, 2003-2004. MMWR Morb Mortal Wkly Rep 2006, 55(17):481-486.
23. Schieve L.A., Gonzalez V., Boulet S.L., et al. Concurrent medical conditions and health care use and needs among children with learning and behavioral developmental disabilities, National Health Interview Survey, 2006-2010. Res Dev Disabil 2012, 33(2):467-476.
24. Burstein M., He J.P., Kattan G., et al. Social phobia and subtypes in the national comorbidity survey-adolescent supplement: prevalence, correlates, and comorbidity. JAm Acad Child Adolesc Psychiatry 2011, 50(9):870-880.
25. Eunice Kennedy Shriver National Institute of Child Health Human Development, NIH, DHHS America's children in brief: key national indicators of well-being, 2012. Federal Interagency Forum on Child and Family Statistics 2012, US Government Printing Office, Washington, DC.
26. Johnson E.O., Roth T., Schultz L., et al. Epidemiology of DSM-IV insomnia in adolescence: lifetime prevalence, chronicity, and an emergent gender difference. Pediatrics 2006, 117(2):e247-e256.
27. Wong H.H., Smith R.G. Patterns of complementary and alternative medical therapy use in children diagnosed with autism spectrum disorders. JAutism Dev Disord 2006, 36(7):901-909.
28. Hagen L.E., Schneider R., Stephens D., et al. Use of complementary and alternative medicine by pediatric rheumatology patients. Arthritis Rheum 2003, 49(1):3-6.
29. Markowitz J.E., Mamula P., delRosario J.F., et al. Patterns of complementary and alternative medicine use in a population of pediatric patients with inflammatory bowel disease. Inflamm Bowel Dis 2004, 10(5):599-605.
30. Roy-Byrne P.P., Bystritsky A., Russo J., et al. Use of herbal medicine in primary care patients with mood and anxiety disorders. Psychosomatics 2005, 46(2):117-122.
31. Sarris J., Panossian A., Schweitzer I., et al. Herbal medicine for depression, anxiety and insomnia: a review of psychopharmacology and clinical evidence. Eur Neuropsychopharmacol 2011, 21(12):841-860.
32. Weber W., Newmark S. Complementary and alternative medical therapies for attention-deficit/hyperactivity disorder and autism. Pediatr Clin North Am 2007, 54(6):983-1006.
33. Kearns G.L., Abdel-Rahman S.M., Alander S.W., et al. Developmental pharmacology-drug disposition, action, and therapy in infants and children. NEngl J Med 2003, 349:1157-1167.
34. Pediatric Pharmacology Research Unit (PPRU) Network. 1994-2010. Available at: Accessed May 16, 2011. http://www.ppru.org/.
35. NCCAM. NCCAM policy: natural product integrity. 2008. Available at: Accessed January 25, 2013. http://nccam.nih.gov/research/policies/naturalproduct.htm.
36. Chen X.W., Sneed K.B., Pan S.Y., et al. Herb-drug interactions, mechanistic and clinical considerations. Curr Drug Metab 2012, 13(5):640-651.
37. Engelberg D., McCutcheon A., Wiseman S. Acase of ginseng-induced mania. JClin Psychopharmacol 2001, 21(5):535-537.
38. LaFrance W.C., Lauterbach E.C., Coffey C.E., et al. The use of herbal alternative medicines in neuropsychiatry. JNeuropsychiatry Clin Neurosci 2000, 12:177-192.
39. Vickers A., Zollman C., Lee R. Herbal medicine. West J Med 2001, 175:125-198.
40. Granger A.S. Ginkgo biloba precipitating epileptic seizures. Age Ageing 2001, 30(6):523-525.
41. Rounsaville B., Carroll K.M., Onken L.S. Astage model of behavioral therapies research: getting started and moving on from stage 1. Clin Psychol Sci Pract 2001, 8(2):133-142.
42. Rosenblatt L.E., Gorantla S., Torres J.A., et al. Relaxation response-based yoga improves functioning in young children with autism: a pilot study. JAltern Complement Med 2011, 17(11):1029-1035.
43. Krisanaprakornkit T., Ngamjarus C., Witoonchart C., et al. Meditation therapies for attention-deficit/hyperactivity disorder (ADHD). Cochrane Database Syst Rev 2010, (6). CD006507.
44. Biegel G.M., Brown K.W., Shapiro S.L., et al. Mindfulness-based stress reduction for the treatment of adolescent psychiatric outpatients: a randomized clinical trial. JConsult Clin Psychol 2009, 77(5):855-866.
45. Sibinga E.M., Kerrigan D., Stewart M., et al. Mindfulness-based stress reduction for urban youth. JAltern Complement Med 2011, 17(3):213-218.
46. Brown K.W., West A.M., Loverich T.M., et al. Assessing adolescent mindfulness: validation of an adapted Mindful Attention Awareness Scale in adolescent normative and psychiatric populations. Psychol Assess 2011, 23(4):1023-1033.
47. La Greca A.M., Bearman K.J., Moore H. Peer relations of youth with pediatric conditions and health risks: promoting social support and healthy lifestyles. JDev Behav Pediatr 2002, 23(4):271-280.
48. Fava M., Mischoulon D. Evaluating the data: limitations of research and quality assurance issues regarding natural remedies. Natural medications for psychiatric disorders: considering the alternatives 2008, 11-23. Lippincott Williams & Wilkins, Philadelphia. 2nd edition. D. Mischoulon, J. Rosenbaum (Eds.).
49. Rapaport M.H., Nierenberg A.A., Howland R., et al. The treatment of minor depression with St. John's Wort or citalopram: failure to show benefit over placebo. JPsychiatr Res 2011, 45(7):931-941.
50. Chen J.A., Papakostas G.I., Youn S.J., et al. Association between patients' beliefs regarding assigned treatment and clinical response: re-analysis of data from the Hypericum Depression Trial Study Group. JClin Psychiatry 2011, 72(12):1669-1676.
51. Mischoulon D., Papakostas G.I., Dording C.M., et al. Adouble-blind, randomized controlled trial of ethyl-eicosapentaenoate for major depressive disorder. JClin Psychiatry 2009, 70:1634-1644.
52. Mischoulon D. Update and critique of natural remedies as antidepressant treatments. Obstet Gynecol Clin North Am 2009, 36:789-807.
53. Vickers A.J., Cronin A.M., Maschino A.C., et al. Acupuncture for chronic pain: individual patient data meta-analysis. Arch Intern Med 2012, 1-10. Acupuncture Trialists' Collaboration.
54. Wu J., Yeung A.S., Schnyer R., et al. Acupuncture for depression: a review of clinical applications. Can J Psychiatry 2012, 57(7):397-405.
55. Bell I.R., Pappas P.A. Homeopathy and its applications in psychiatry. Natural medications for psychiatric disorders: considering the alternatives 2008, 303-320. Lippincott Williams & Wilkins, Philadelphia. 2nd edition. D. Mischoulon, J. Rosenbaum (Eds.).
56. Yeung A.S., Ameral B.E., Chuzi S.E., et al. Apilot study of acupuncture augmentation therapy in antidepressant partial and non-responders with major depressive disorder. JAffect Disord 2011, 130(1-2):285-289.
57. Mischoulon D., Brill C.D., Ameral V.E., et al. Apilot study of acupuncture monotherapy in patients with major depressive disorder. JAffect Disord 2012, 141(2-3):469-473.
58. Murray T.L. The other side of psychopharmacology: a review of the literature. JMHC 2006, 28(4):309-337.
59. Devi S. Antidepressant-suicide link in children questioned. Lancet 2012, 379(9818):791.
60. Julious S.A. Efficacy and suicidal risk for antidepressants in paediatric and adolescent patients. Stat Methods Med Res 2012, 10.1177/0962280211432210.
61. Greenspan S.I. Overcoming ADHD: helping your child become calm, engaged, and focused-without a pill 2009, Da Capo Lifelong Books, Cambridge, MA.
62. Veracity D. Experts say antidepressant drugs cause suicides instead of preventing them. Available at: Accessed August 23, 2012. http://www.naturalnews.com/019342.html#ixzz24P56vpWO.