Unexpected new roles for heparanase in Type 1 diabetes and immune gene regulation

Matrix Biology

Volumn 32, Issue 5, 2013, Pages 228-233

  Parish, C R ^a   Freeman, C ^a   Ziolkowski, A F ^a   He, Y Q ^a,b   Sutcliffe, E L ^a,c   Zafar, A ^a,c   Rao, S ^a,c   Simeonovic, C J ^a  

^a Biology and Environment   (Australia)

^b SUN YAT SEN UNIVERSITY   (China)

^c UNIVERSITY OF CANBERRA   (Australia)

Author keywords

Basement membrane; Gene transcription; Heparan sulfate; Heparanase; Leukocyte migration; Type 1 diabetes

Indexed keywords

FREE RADICAL; HEPARANASE; HISTONE H3; LYSINE; MICRORNA; PI 88;

ANIMAL EXPERIMENT; ANIMAL MODEL; CATALYSIS; CELL ADHESION; CELL DEATH; CELL INVASION; CELL NUCLEUS; CELL SURFACE; CELL SURVIVAL; DISEASE COURSE; ENZYME ACTIVITY; FEMALE; GENE CONTROL; GENE TARGETING; GENETIC TRANSCRIPTION; HISTONE METHYLATION; IMMUNOFLUORESCENCE MICROSCOPY; INSULIN DEPENDENT DIABETES MELLITUS; INSULITIS; LEUKEMIA CELL LINE; LYMPHOCYTE DIFFERENTIATION; MONONUCLEAR CELL; MOUSE; NONHUMAN; NUCLEAR LOCALIZATION SIGNAL; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; REVIEW; T LYMPHOCYTE; UPREGULATION;

ANIMALS; CELL PROLIFERATION; DIABETES MELLITUS, TYPE 1; ENZYME INHIBITORS; EXTRACELLULAR MATRIX; FREE RADICALS; GENE EXPRESSION REGULATION; GLUCURONIDASE; HEPARITIN SULFATE; HUMANS; ISLETS OF LANGERHANS; MICE; OLIGOSACCHARIDES; SIGNAL TRANSDUCTION; T-LYMPHOCYTES;

MUS;

EID: 84879602921     PISSN: 0945053X     EISSN: 15691802     Source Type: Journal    
DOI: 10.1016/j.matbio.2013.02.007     Document Type: Review

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