Generation and characterization of KsprtTA and KsptTA transgenic mice

Genesis

Volumn 51, Issue 6, 2013, Pages 430-435

  Pan, Xinchao ^a,b   Small, Erin V ^a,b   Igarashi, Peter ^a   Carroll, Thomas J ^a,b  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

Kidney development; Kidney epithelium; Kidney tubule; Tet off; Tet on

Indexed keywords

CADHERIN; CADHERIN 16; COMPLEMENTARY DNA; DOXYCYCLINE; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR REVERSE TET ACTIVATOR; TRANSCRIPTION FACTOR TET ACTIVATOR; UNCLASSIFIED DRUG; CDH16 PROTEIN, MOUSE; CRE RECOMBINASE; INTEGRASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; EMBRYO DEVELOPMENT; FEMALE; KIDNEY COLLECTING TUBULE; KIDNEY DEVELOPMENT; KIDNEY EPITHELIUM; KIDNEY PROXIMAL TUBULE; MALE; MOUSE; NEPHRON; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; UROGENITAL SYSTEM; ANIMAL; CYTOLOGY; EMBRYOLOGY; EPITHELIUM CELL; GENE EXPRESSION REGULATION; GENETICS; KIDNEY; METABOLISM; ORGAN CULTURE TECHNIQUE; PREGNANCY; PROMOTER REGION; TRANSCRIPTION INITIATION; TRANSGENIC MOUSE;

MUS; MUS MUSCULUS;

ANIMALS; CADHERINS; DOXYCYCLINE; EPITHELIAL CELLS; FEMALE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; INTEGRASES; KIDNEY; MICE; MICE, TRANSGENIC; NEPHRONS; ORGAN CULTURE TECHNIQUES; PREGNANCY; PROMOTER REGIONS, GENETIC; TRANSCRIPTIONAL ACTIVATION;

EID: 84879600430     PISSN: 1526954X     EISSN: 1526968X     Source Type: Journal    
DOI: 10.1002/dvg.22381     Document Type: Article

References (12)

1. Adams DC, Oxburgh L. 2009. The long-term label retaining population of the renal papilla arises through divergent regional growth of the kidney. Am J Physiol Renal Physiol 297:F809-F815.
2. Bai Y, Pontoglio M, Hiesberger T, Sinclair AM, Igarashi P. 2002. Regulation of kidney-specific Ksp-cadherin gene promoter by hepatocyte nuclear factor-1beta. Am J Physiol Renal Physiol 283:F839-F851.
3. Bockamp E, Maringer M, Spangenberg C, Fees S, Fraser S, Eshkind L, Oesch F, Zabel B. 2002. Of mice and models: improved animal models for biomedical research. Physiol Genomics 11:115-132.
4. Gossen M, Bujard H. 1992. Tight control of gene expression in mammalian cells by tetracycline-responsive promoters. Proc Natl Acad Sci USA 89:5547-5551.
5. Gossen M, Freundlieb S, Bender G, Muller G, Hillen W, Bujard H. 1995. Transcriptional activation by tetracyclines in mammalian cells. Science 268:1766-1769.
6. Karner CM, Chirumamilla R, Aoki S, Igarashi P, Wallingford JB, Carroll TJ. 2009. Wnt9b signaling regulates planar cell polarity and kidney tubule morphogenesis. Nat Genet 41:793-799.
7. Patel V, Li L, Cobo-Stark P, Shao X, Somlo S, Lin F, Igarashi P. 2008. Acute kidney injury and aberrant planar cell polarity induce cyst formation in mice lacking renal cilia. Hum Mol Genet 17:1578-1590.
8. Rossi FM, Blau HM. 1998. Recent advances in inducible gene expression systems. Curr Opin Biotechnol 9:451-456.
9. Shao X, Johnson JE, Richardson JA, Hiesberger T, Igarashi P. 2002a. A minimal Ksp-cadherin promoter linked to a green fluorescent protein reporter gene exhibits tissue-specific expression in the developing kidney and genitourinary tract. J Am Soc Nephrol 13:1824-1836.
10. Shao X, Somlo S, Igarashi P. 2002b. Epithelial-specific Cre/lox recombination in the developing kidney and genitourinary tract. J Am Soc Nephrol 13:1837-1846.
11. Thomson RB, Aronson PS. 1999. Immunolocalization of Ksp-cadherin in the adult and developing rabbit kidney. Am J Physiol 277:F146-F156.
12. Tumbar T, Guasch G, Greco V, Blanpain C, Lowry WE, Rendl M, Fuchs E. 2004. Defining the epithelial stem cell niche in skin. Science 303:359-363.