Mediastinal lymphadenectomy in elderly patients with non-small-cell lung cancer

European Journal of Cardio-thoracic Surgery

Volumn 44, Issue 1, 2013, Pages 88-92

  Rivera, Caroline ^a   Falcoz, Pierre Emmanuel ^b   Rami Porta, Ramón ^c   Velly, Jean François ^a   Begueret, Hugues ^a   Roques, Xavier ^a   Dahan, Marcel ^d   Jougon, Jacques ^a  

^a UNIVERSITÉ DE BORDEAUX   (France)

^b UNIVERSITÉ DE STRASBOURG   (France)

^c UNIVERSITY OF BARCELONA   (Spain)

^d UNIVERSITÉ DE TOULOUSE   (France)

Author keywords

Elderly; Geriatric oncology; Lung cancer surgery; Lymph nodes

Indexed keywords

ADULT; AGED; ARTICLE; CANCER INCIDENCE; COMPARATIVE STUDY; CONTROLLED STUDY; ELDERLY CARE; FEMALE; GROUPS BY AGE; HISTOLOGY; HUMAN; LUNG HILUS; LUNG LOBECTOMY; LUNG NON SMALL CELL CANCER; LUNG RESECTION; LYMPH NODE DISSECTION; LYMPH NODE METASTASIS; LYMPH NODE RATIO; MAJOR CLINICAL STUDY; MALE; MEDIASTINAL LYMPHADENECTOMY; MEDIASTINUM LYMPH NODE; POPULATION BASED CASE CONTROL STUDY; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RETROSPECTIVE STUDY; SEX RATIO; TREATMENT OUTCOME;

ELDERLY; GERIATRIC ONCOLOGY; LUNG CANCER SURGERY; LYMPH NODES;

AGED; CARCINOMA, NON-SMALL-CELL LUNG; CASE-CONTROL STUDIES; CHI-SQUARE DISTRIBUTION; FEMALE; HUMANS; LUNG NEOPLASMS; LYMPH NODE EXCISION; LYMPH NODES; MALE; MEDIASTINUM; MIDDLE AGED; NEOPLASM METASTASIS; RETROSPECTIVE STUDIES;

EID: 84879587269     PISSN: 10107940     EISSN: 1873734X     Source Type: Journal    
DOI: 10.1093/ejcts/ezs586     Document Type: Article

References (20)

1. Gridelli C, Rossi A, Maione P. Challenges treating older non-small cell lung cancer patients. Ann Oncol 2008;19(Suppl 7):vii109-vii13.
2. Rivera C, Dahan M, Bernard A, Falcoz PE, Thomas P. Surgical treatment of lung cancer in the octogenarians: results of a nationwide audit. Eur J Cardiothorac Surg 2010;39:981-6.
3. Rivera C, Falcoz PE, Bernard A, Thomas PA, Dahan M. Surgical management and outcomes of elderly patients with early stage non-small cell lung cancer: a nested case-control study. Chest 2011;140:874-80.
4. Rivera C, Jougon J, Dahan M, Falcoz PE, Bernard A, Brouchet L. Are postoperative consequences of neoadjuvant chemotherapy for non-small cell lung cancer more severe in elderly patients? Lung Cancer 2011;76:216-21.
5. Okami J, Ito Y, Higashiyama M, Nakayama T, Tokunaga T, Maeda J et al. Sublobar resection provides an equivalent survival after lobectomy in elderly patients with early lung cancer. Ann Thorac Surg 2010;90:1651-6.
6. Okasaka T, Usami N, Taniguchi T, Kawaguchi K, Okagawa T, Suzuki H, et al. Can non-performance of radical systematic mediastinal lymphadenectomy be justified in elderly lung cancer patients? An evaluation using propensity-based survival analysis. Eur J Cardiothorac Surg 2010;38: 27-33.
7. Falcoz PE, Conti M, Brouchet L, Chocron S, Puyraveau M, Mercier M, et al. The Thoracic surgery scoring system (Thoracoscore): risk model for in-hospital death in 15,183 patients requiring thoracic surgery. J Thorac Cardiovasc Surg 2007;133:325-32.
8. Bernard A, Rivera C, Pages PB, Falcoz PE, Vicaut E, Dahan M. Risk model of in-hospital mortality after pulmonary resection for cancer: a national database of the French Society of Thoracic and Cardiovascular Surgery (Epithor). J Thorac Cardiovasc Surg 2011;141:449-58.
9. Oken MM, Creech RH, Tormey DC, Horton J, Davis TE, McFadden ET, et al. Toxicity and response criteria of the Eastern Cooperative Oncology Group. Am J Clin Oncol 1982;5:649-55.
10. Edge SB, Byrd DR, Compton CC, Fritz AG, Greene FL, Trotti A (eds). AJCC cancer staging manual (7th ed). New York, NY: Springer, 2010;299-323.
11. Wisnivesky JP, Arciniega J, Mhango G, Mandeli J, Halm EA. Lymph node ratio as a prognostic factor in elderly patients with pathological N1 nonsmall cell lung cancer. Thorax 2010;66:287-93.
12. Fulop T, Larbi A, Kotb R, de Angelis F, Pawelec G. Aging, immunity, and cancer. Discov Med 2011;11:537-50.
13. Inoue M, Sawabata N, Takeda S, Ohta M, Ohno Y, Maeda H. Results of surgical intervention for p-stage IIIA (N2) non-small cell lung cancer: acceptable prognosis predicted by complete resection in patients with single N2 disease with primary tumor in the upper lobe. J Thorac Cardiovasc Surg 2004;127:1100-6.
14. Misthos P, Sepsas E, Kokotsakis J, Skottis I, Lioulias A. The significance of one-station N2 disease in the prognosis of patients with nonsmall-cell lung cancer. Ann Thorac Surg 2008;86:1626-30.
15. Roth JA, Fossella F, Komaki R, Ryan MB, Putnam JB Jr, Lee JS, et al. A randomized trial comparing perioperative chemotherapy and surgery with surgery alone in resectable stage IIIA non-small-cell lung cancer. J Natl Cancer Inst 1994;86:673-80.
16. Betticher DC, Hsu Schmitz SF, Totsch M, Hansen E, Joss C, von Briel C, et al. Mediastinal lymph node clearance after docetaxel-cisplatin neoadjuvant chemotherapy is prognostic of survival in patients with stage IIIA pN2 non-small-cell lung cancer: a multicenter phase II trial. J Clin Oncol 2003;21:1752-9.
17. Lorent N, De Leyn P, Lievens Y, Verbeken E, Nackaerts K, Dooms C, et al. Long-term survival of surgically staged IIIA-N2 non-small-cell lung cancer treated with surgical combined modality approach: analysis of a 7-year prospective experience. Ann Oncol 2004;15:1645-53.
18. Nwogu CE, Groman A, Fahey D, Yendamuri S, Dexter E, Demmy TL, et al. Number of lymph nodes and metastatic lymph node ratio are associated with survival in lung cancer. Ann Thorac Surg 2012;93:1614-20.
19. Tanaka F, Yanagihara K, Otake Y, Yamada T, Shoji T, Miyahara R, et al. Prognostic factors in patients with resected pathologic (p-) T1-2N1M0 nonsmall cell lung cancer (NSCLC). Eur J Cardiothorac Surg 2001;19:555-61.
20. Vesselle H, Salskov A, Turcotte E, Wiens L, Schmidt R, Jordan CD, et al. Relationship between non-small cell lung cancer FDG uptake at PET, tumor histology, and Ki-67 proliferation index. J Thorac Oncol 2008;3:971-8.