Nitric oxide coordinates development of genomic instability in realization of combined effect with ionizing radiation

Experimental Oncology

Volumn 35, Issue 1, 2013, Pages

  Mikhailenko, V M ^a   Diomina, E A ^a   Muzalov, I I ^a   Gerashchenko, B I ^a  

^a R E KAVETSKY INSTITUTE OF EXPERIMENTAL PATHOLOGY   (Ukraine)

Author keywords

DNA damage; Genomic instability; Ionizing radiation; Nitric oxide; Nitrosative stress; S Nitrosothiols

Indexed keywords

FREE RADICAL; METHEMOGLOBIN; NITRIC OXIDE; NITROGEN DERIVATIVE; NITROGEN OXIDE; REACTIVE OXYGEN METABOLITE; S NITROSOGLUTATHIONE; HEMOGLOBIN; REACTIVE NITROGEN SPECIES; S-NITROSOHEMOGLOBIN; S NITROSOHEMOGLOBIN;

ARTICLE; CHROMATID; CHROMOSOME ABERRATION; COMET ASSAY; CONTROLLED STUDY; CYTOGENETICS; DNA DAMAGE; DONOR; ELECTRON SPIN RESONANCE; FLUOROMETRY; GENOMIC INSTABILITY; GENOTOXICITY; HUMAN; IN VITRO STUDY; IN VIVO STUDY; IONIZING RADIATION; MALE; METAPHASE; NONHUMAN; PERIPHERAL LYMPHOCYTE; PROTEIN PROCESSING; RAT; SPECTROPHOTOMETRY; X IRRADIATION; ANIMAL; BLOOD; CELL CULTURE; DNA REPAIR; DRUG EFFECTS; LYMPHOCYTE; METABOLISM; OXIDATIVE STRESS; RADIATION RESPONSE; DRUG EFFECT; RADIATION EXPOSURE;

ANIMALS; CELLS, CULTURED; CHROMOSOME ABERRATIONS; DNA DAMAGE; DNA REPAIR; GENOMIC INSTABILITY; HEMOGLOBINS; HUMANS; LYMPHOCYTES; MALE; METHEMOGLOBIN; NITRIC OXIDE; OXIDATIVE STRESS; RADIATION, IONIZING; RATS; REACTIVE NITROGEN SPECIES; REACTIVE OXYGEN SPECIES; S-NITROSOGLUTATHIONE;

EID: 84879585861     PISSN: 18129269     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (44)

1. Jaiswal M, LaRusso NF, Shapiro RA, et al. Nitric oxide - mediated inhibition of DNA repair potentiates oxidative DNA damage in cholangiocytes. Gastroenterology 2001; 120: 190-9. (Pubitemid 32061883)
2. Bourret TJ, Boylan JA, Lawrence KA, et al. Nitrosative damage to free and zinc-bound cysteine thiols underlies nitric oxide toxicity in wild-type Borrelia burgdorferimmi. Mol Microbiol 2011; 81: 259-73.
3. Suzuki K, Yamashita S. Low-dose radiation exposure and carcinogenesis. Jpn J Clin Oncol 2012; 42: 563-68.
4. Switzer CH, Glynn SA, Ridnour LA, et al. Nitric oxide and protein phosphatase 2A provide novel therapeutic opportunities in ER-negative breast cancer. Trends Pharmacol Sci 2011; 32: 644-51.
5. Aranda E, López-Pedrera C, De La Haba-Rodriguez JR, et al. Nitric oxide and cancer: the emerging role of S-nitrosylation. Curr Mol Med 2012; 12: 50-67.
6. Bonavida B. Nitric Oxide (NO) and Cancer Prognosis, Prevention, and Therapy. New York: Springer, 2010.
7. Li CQ, Pang B, Kiziltepe T, et al. Threshold effects of nitric oxide-induced toxicity and cellular responses in wild-type and p53-null human lymphoblastoid cells. Chem Res Toxicol 2006; 19: 399-406.
8. Luckey TD. The health effects of low-dose ionizing radiation. J Am Phys Surg 2008; 13: 39-42.
9. Marley R, Patel RP, Orie N. Formation of nanomolar concentrations of S-nitroso-albumin in human plasma by nitric oxide. Free Radical Biol Med 2001; 31: 688-96. (Pubitemid 32777870)
10. Vanin AF. Dinitrosyl iron complexes and S-nitrosothiols - two possible forms of stabilization and transport of nitric oxide in biological systems. Biochem 1998; 63: 924-38 (in Russian).
11. Vanin AF. Nitric oxide - a regulator of cellular metabolism. Sor Ed J 2001; 7: 7-12 (in Russian).
12. Jourd'heuil D, Jourd'heuil FL, Feelisch M. Oxidation and nitrosation of thiols at low micromolar exposure to nitric oxide. Evidence for a free radical mechanism. J Biol Chem 2003; 278: 15720-6. (Pubitemid 36799683)
13. Yang Y, Loscalzo J. S-nitrosoprotein formation and localization in endothelial cells. Proc Natl Acad Sci 2005; 102: 117-22. (Pubitemid 40094438)
14. Rouzer C. Dissecting nitric oxide's toxicity. Chem Res Toxicol 2012; 25: 765-6.
15. Proskuryakov SJ, Konoplyannikova OA, et al. Influence of some inhibitors of NOS-thiazolium dihydrotiazinum series on post-radiation recovery of CFU-S-8 in mice. Rad Biol Radioecol 2007; 47: 5-9 (in Russian).
16. Gow AJ, Chen Q, Hess DT, et al. Basal and stimulated protein S-nitrosylation in multiple cell types and tissues. J Biol Chem 2002; 277: 9637-40. (Pubitemid 34968060)
17. Zhuang JC, Lin C, Lin D, et al. Mutagenesis associated with nitric oxide production in macrophages. Proc Natl Acad Sci 1998; 95: 8286-91. (Pubitemid 28326105)
18. Ortega ÁL, Mena S, Estrela JM. Oxidative and nitrosative stress in the metastatic microenvironment. Cancers 2010; 2: 274-304.
19. Bryant PE, Riches AC, Terry SY. Mechanisms of the formation of radiation-induced chromosomal aberrations. Mutat Res 2010; 701: 23-6.
20. Fungtammasan A, Walsh E, Chiaromonte F. A genome-wide analysis of common fragile sites: What features determine chromosomal instability in the human genome. Genome Res 2012; 22: 993-1005.
21. Glen CD, Dubrova YE. Exposure to anticancer drugs can result in transgenerational genomic instability in mice. Proc Natl Acad Sci 2012; 109: 2984-8.
22. Jha A. Ecotoxicological applications and significance of the comet assay. Mutagenesis 2008; 23: 207-2.
23. Burlinson B. The in vitro and in vivo comet assays. Methods Mol Biol 2012; 817: 143-63.
24. Fröhling S, Döhner H. Chromosomal abnormalities in cancer. N Engl J Med 2008; 359: 722-34.
25. Gordon DJ, Resio B, Pellman D. Causes and consequences of aneuploidy in cancer. Nat Rev Genet 2012; 13: 189-203.
26. Demina EA, Pilinska MA, Petunin YI, Klyushin DA. Radiation cytogenetics. Kiev: Health Protection, 2009 (in Russian).
27. Kozhem'yakin YM, Khromov DC, Filonenko MA, Sayfetdinova GA. Scientific and practical advice on the maintenance of laboratory animals and work with them. Kiev, Avitsena, 2002 (in Ukrainian).
28. Mikhailenko VM, Savtsova ZD, Glavin OA, et al. Effect of environmental nitric oxides on the antitumor resistance of rats. Exp Oncol 2005; 27: 65-70. (Pubitemid 40547665)
29. Kostka P, Park JK. Fluorometric detection of S-Nitrosothiols. Meth Enzymol 1999; 301: 227-35. (Pubitemid 28489784)
30. Kuo KL, Hung SC, Wie YH, Tarng DC. Intravenous iron exacerbates oxidative DNA damage in peripheral blood lymphocytes in chronic hemodialysis patients. J Am Soc Nephrol 2008; 19: 1817-26.
31. Hayashi I, Morishita Y, Imai K, et al. High-throughput spectrophotometric assay of reactive oxygen species in serum. Mutat Res 2007; 631: 55-61. (Pubitemid 46809621)
32. Collins AR, Oscoz AA, Brunborg G, et al. The comet assay: topical issues. Mutagenesis 2008; 23: 143-51.
33. Collins AR. The comet assay for DNA damage and repair: principles, applications and limitations. Mol Biotechnol 2004; 26: 259-61.
34. Hagmar L, Strömberg U, Bonassi S, et al. Impact of types of lymphocyte chromosomal aberrations on human cancer risk: results from Nordic and Italian cohorts. Cancer Res 2004; 64: 2258-63. (Pubitemid 38339481)
35. Lakin GF. Biometrics. Moscow, Higher School, 1990 (in Russian).
36. Spencer NY, Zeng H, Patel RP, et al. Reaction of S-Nitrosoglutathione with the heme group of deoxyhemoglobin. J Biol Chem 2000; 275: 36562-7. (Pubitemid 32002054)
37. Gow AJ, Buerk DG, Ischiropoulos H. A novel reaction mechanism for the formation of S-Nitrosothiol in vivo. J Biol Chem 1997; 272: 2841-5. (Pubitemid 27053331)
38. Hartman A, Plappert U, Poetter F, et al. Comparative study with the alkaline comet assay and the chromosome aberration test. Mutat Res 2003; 536: 27-38. (Pubitemid 36411654)
39. Dikomey E, Daphi J, Brammer I. Correlation between cellular radiosensitivity and non-repaired double-strand breaks studied in nine mammalian cell lines. Int J Radiat Biol 1998; 73: 269-78. (Pubitemid 28160913)
40. Chandna S, Dwarakanath BS, Khaitan D, et al. Low-dose radiation hypersensitivity in human tumor cell lines: effects of cell-cell contact and nutritional deprivation. Radiat Res 2002; 157: 516-25. (Pubitemid 34492558)
41. Mitelman F. Recurrent chromosome aberrations in cancer. Mutat Res 2000; 462: 247-53. (Pubitemid 30190232)
42. Rossner P, Boffetta P, Ceppi M. Chromosomal aberrations in lymphocytes of healthy subjects and risk of cancer. Environ Health Perspect 2005; 113: 517-20. (Pubitemid 40711337)
43. Boffetta P, Norppa H, Fabianova E. Chromosomal aberrations and cancer risk: results of a cohort study from central Europe. Am J Epidemiol 2007; 165: 36-43. (Pubitemid 46026207)
44. Radford L. Chromosomal rearrangement as the basis for human tumorigenesis. Int J Radiat Res 2004; 80: 543-57.