-
1
-
-
84869496369
-
Global burden of cancer: Opportunities for prevention
-
Jemal A. Global burden of cancer: opportunities for prevention. Lancet. 2012;380 (9856):1797-9.
-
(2012)
Lancet
, vol.380
, Issue.9856
, pp. 1797-1799
-
-
Jemal, A.1
-
2
-
-
0038188668
-
Nitric oxide promotes p53 nuclear retention and sensitizes neuroblastoma cells to apoptosis by ionizing radiation
-
Wang X, Zalcenstein A, Oren M. Nitric oxide promotes p53 nuclear retention and sensitizes neuroblastoma cells to apoptosis by ionizing radiation. Cell Death Differentiation. 2003;10(4):468-76.
-
(2003)
Cell Death Differentiation
, vol.10
, Issue.4
, pp. 468-476
-
-
Wang, X.1
Zalcenstein, A.2
Oren, M.3
-
3
-
-
31544445749
-
Paclitaxel-induced nuclear translocation of FOXO3a in breast cancer cells is mediated by c-Jun NH2-terminal kinase and Akt
-
Sunters A. Madureira PA, Pomeranz KM, Aubert M, Brosens JJ, Cook SJ, et al. Paclitaxel-induced nuclear translocation of FOXO3a in breast cancer cells is mediated by c-Jun NH2-terminal kinase and Akt. Can Research. 2006;66(1):212-20.
-
(2006)
Can Research
, vol.66
, Issue.1
, pp. 212-220
-
-
Sunters, A.1
Madureira, P.A.2
Pomeranz, K.M.3
Aubert, M.4
Brosens, J.J.5
Cook, S.J.6
-
4
-
-
84864917378
-
Association between the nuclear to cytoplasmic ratio of p27 and the efficacy of adjuvant polychemotherapy in early breast cancer
-
Andre F, Conforti R, Moeder CB, Mauguen A, Arnedos M, Berrada N, et al. Association between the nuclear to cytoplasmic ratio of p27 and the efficacy of adjuvant polychemotherapy in early breast cancer. Ann Oncol. 2012;23(8):2059-64.
-
(2012)
Ann Oncol
, vol.23
, Issue.8
, pp. 2059-2064
-
-
Andre, F.1
Conforti, R.2
Moeder, C.B.3
Mauguen, A.4
Arnedos, M.5
Berrada, N.6
-
5
-
-
61649105802
-
Sullivan DM.CRM1-mediated nuclear export of proteins and drug resistance in cancer
-
Turner JG, Sullivan DM.CRM1-mediated nuclear export of proteins and drug resistance in cancer. Curr Med Chemistry. 2008;15(26):2648-55.
-
(2008)
Curr Med Chemistry
, vol.15
, Issue.26
, pp. 2648-2655
-
-
Turner, J.G.1
-
6
-
-
84858005605
-
Nuclear export of proteins and drug resistance in cancer
-
Turner JG, Dawson J, Sullivan DM. Nuclear export of proteins and drug resistance in cancer. Biochem Pharmacol. 2012;83(8): 1021-32.
-
(2012)
Biochem Pharmacol
, vol.83
, Issue.8
, pp. 1021-1032
-
-
Turner, J.G.1
Dawson, J.2
Sullivan, D.M.3
-
7
-
-
33947726050
-
CRM1-mediated nuclear export: To the pore and beyond
-
Hutten S, Kehlenbach RH. CRM1-mediated nuclear export: to the pore and beyond. Tren Cell Biol. 2007;17(4):193-01.
-
(2007)
Tren Cell Biol
, vol.17
, Issue.4
, pp. 101-193
-
-
Hutten, S.1
Kehlenbach, R.H.2
-
8
-
-
0030924190
-
CRM1 is an export receptor for leucinerich nuclear export signals
-
Fornerod M, Ohno M, Yoshida M, Mattaj IW. CRM1 is an export receptor for leucinerich nuclear export signals. Cell. 1997;90(6): 1051-60.
-
(1997)
Cell
, vol.90
, Issue.6
, pp. 1051-1060
-
-
Fornerod, M.1
Ohno, M.2
Yoshida, M.3
Mattaj, I.W.4
-
9
-
-
0347747970
-
A chemical genetic screen identifies inhibitors of regulated nuclear export of a Forkhead transcription factor in PTEN-deficient tumor cells
-
Kau TR, Schroeder F, Ramaswamy S, Wojciechowski CL, Zhao JJ, Roberts TM, et al. A chemical genetic screen identifies inhibitors of regulated nuclear export of a Forkhead transcription factor in PTEN-deficient tumor cells. Cancer Cell. 2003;4(6): 463-76.
-
(2003)
Cancer Cell
, vol.4
, Issue.6
, pp. 463-476
-
-
Kau, T.R.1
Schroeder, F.2
Ramaswamy, S.3
Wojciechowski, C.L.4
Zhao, J.J.5
Roberts, T.M.6
-
10
-
-
1042278767
-
Nuclear transport and cancer: From mechanism to intervention
-
Kau TR, Way JC, Silver PA. Nuclear transport and cancer: from mechanism to intervention. Nat Rev Cancer. 2004;4(2):106-17.
-
(2004)
Nat Rev Cancer
, vol.4
, Issue.2
, pp. 106-117
-
-
Kau, T.R.1
Way, J.C.2
Silver, P.A.3
-
11
-
-
84877791472
-
Targeting the nuclear transport machinery by rational drug design
-
Mao L, Yang Y. Targeting the nuclear transport machinery by rational drug design. Curr Pharm Design. 2013;19(12):2318-25.
-
(2013)
Curr Pharm Design
, vol.19
, Issue.12
, pp. 2318-2325
-
-
Mao, L.1
Yang, Y.2
-
13
-
-
58349104143
-
Identification of nuclear export inhibitors with potent anticancer activity in vivo
-
Mutka SC, Yang WQ, Dong SD, Ward SL, Craig DA, Timmernmans PB, et al. Identification of nuclear export inhibitors with potent anticancer activity in vivo. Cancer Res. 2009;69(2):510-7.
-
(2009)
Cancer Res
, vol.69
, Issue.2
, pp. 510-517
-
-
Mutka, S.C.1
Yang, W.Q.2
Dong, S.D.3
Ward, S.L.4
Craig, D.A.5
Timmernmans, P.B.6
-
14
-
-
80053619765
-
CBS9106 is a novel reversible oral CRM1 inhibitor with CRM1 degrading activity
-
Sakakibara K, Saito N, Sato T, Suzuki A, Hasegawa Y, Friedman JM, et al. CBS9106 is a novel reversible oral CRM1 inhibitor with CRM1 degrading activity. Blood. 2011;118 (14):3922-31.
-
(2011)
Blood
, vol.118
, Issue.14
, pp. 3922-3931
-
-
Sakakibara, K.1
Saito, N.2
Sato, T.3
Suzuki, A.4
Hasegawa, Y.5
Friedman, J.M.6
-
15
-
-
84879599706
-
Selective inhibitors of nuclear export block pancreatic cancer cell proliferation and reduce tumor growth in mice
-
Azmi AS, Aboukameel A, Bao B, Sarkar FH, Philip PA, Kauffman M, et al. Selective inhibitors of nuclear export block pancreatic cancer cell proliferation and reduce tumor growth in mice. Gastroenterology 2012. pii: S0016-5085(12)01552-1.
-
(2012)
Gastroenterology
, Issue.12
-
-
Azmi, A.S.1
Aboukameel, A.2
Bao, B.3
Sarkar, F.H.4
Philip, P.A.5
Kauffman, M.6
-
16
-
-
84877601009
-
CRM1 blockade by selective inhibitors of nuclear export (SINE) attenuates kidney cancer growth
-
Inoue H, Kauffman M, Shacham S, Landesman Y, Yang J, Evans CP, et al. CRM1 blockade by selective inhibitors of nuclear export (SINE) attenuates kidney cancer growth. J Urol. 2013;189(6):2317-26.
-
(2013)
J Urol
, vol.189
, Issue.6
, pp. 2317-2326
-
-
Inoue, H.1
Kauffman, M.2
Shacham, S.3
Landesman, Y.4
Yang, J.5
Evans, C.P.6
-
17
-
-
84870502798
-
Selective inhibitors of nuclear export show that CRM1/XPO1 is a target in chronic lymphocytic leukemia
-
Lapalombella R, Sun Q, Williams K, Tangeman L, Jha S, Zhong Y, et al. Selective inhibitors of nuclear export show that CRM1/XPO1 is a target in chronic lymphocytic leukemia. Blood. 2012;120(23):4621-34.
-
(2012)
Blood
, vol.120
, Issue.23
, pp. 4621-4634
-
-
Lapalombella, R.1
Sun, Q.2
Williams, K.3
Tangeman, L.4
Jha, S.5
Zhong, Y.6
-
18
-
-
84865749132
-
Preclinical activity of a novel CRM1 inhibitor in acute myeloid leukemia
-
Ranganathan P, Yu X, Na C, Santhanam R, Shacham S, Kauffman M, et al. Preclinical activity of a novel CRM1 inhibitor in acute myeloid leukemia. Blood. 2012;120(9): 1765-73.
-
(2012)
Blood
, vol.120
, Issue.9
, pp. 1765-1773
-
-
Ranganathan, P.1
Yu, X.2
Na, C.3
Santhanam, R.4
Shacham, S.5
Kauffman, M.6
-
19
-
-
67749143838
-
SMI of Bcl-2 TW-37 is active across a spectrum of B-cell tumors irrespective of their proliferative and differentiation status
-
Al-Katib AM, Sun Y, Goustin AS, Azmi AS, Chen B, et al. SMI of Bcl-2 TW-37 is active across a spectrum of B-cell tumors irrespective of their proliferative and differentiation status. J Hematol Oncol. 2009;2:8.
-
(2009)
J Hematol Oncol
, vol.2
, pp. 8
-
-
Al-Katib, A.M.1
Sun, Y.2
Goustin, A.S.3
Azmi, A.S.4
Chen, B.5
-
20
-
-
0027336771
-
Propagation of Waldenstrom's macroglobulinemia cells in vitro and in severe combined immune deficient mice: Utility as a preclinical drug screening model
-
Al-Katib A, Mohammad R, Hamdan M, Mohamed AN, Dan M, Smith MR. Propagation of Waldenstrom's macroglobulinemia cells in vitro and in severe combined immune deficient mice: utility as a preclinical drug screening model. Blood. 1993;81(11):3034-42.
-
(1993)
Blood
, vol.81
, Issue.11
, pp. 3034-3042
-
-
Al-Katib, A.1
Mohammad, R.2
Hamdan, M.3
Mohamed, A.N.4
Dan, M.5
Smith, M.R.6
-
21
-
-
78650978663
-
MI-219-zinc combination: A new paradigm in MDM2 inhibitor-based therapy
-
Azmi AS, Philip PA, Beck FW, Wang Z, Banerjee S, Wang S, et al. MI-219-zinc combination: a new paradigm in MDM2 inhibitor-based therapy. Oncogene. 2011;30 (1):117-26.
-
(2011)
Oncogene
, vol.30
, Issue.1
, pp. 117-126
-
-
Azmi, A.S.1
Philip, P.A.2
Beck, F.W.3
Wang, Z.4
Banerjee, S.5
Wang, S.6
-
22
-
-
13944252626
-
Preclinical studies of a nonpeptidic small-molecule inhibitor of Bcl-2 and Bcl-X(L) [(-)-gossypol] against diffuse large cell lymphoma
-
Mohammad RM, Wang S, Aboukameel A, Chen B, Wu X, Chen J, et al. Preclinical studies of a nonpeptidic small-molecule inhibitor of Bcl-2 and Bcl-X(L) [(-)-gossypol] against diffuse large cell lymphoma. Mol Can Therapy. 2005; 4(1):13-21.
-
(2005)
Mol Can Therapy
, vol.4
, Issue.1
, pp. 13-21
-
-
Mohammad, R.M.1
Wang, S.2
Aboukameel, A.3
Chen, B.4
Wu, X.5
Chen, J.6
-
23
-
-
80051741587
-
Network modeling of MDM2 inhibitor-oxaliplatin combination reveals biological synergy in wt-p53 solid tumors
-
Azmi AS, Banerjee S, Ali S, Wang Z, Bao B, Beck FW, et al. Network modeling of MDM2 inhibitor-oxaliplatin combination reveals biological synergy in wt-p53 solid tumors. Oncotarget. 2011;2(5):378-92.
-
(2011)
Oncotarget
, vol.2
, Issue.5
, pp. 378-392
-
-
Azmi, A.S.1
Banerjee, S.2
Ali, S.3
Wang, Z.4
Bao, B.5
Beck, F.W.6
-
24
-
-
0034486490
-
The addition of bryostatin 1 to cyclophosphamide, doxorubicin, vincristine, and prednisone (CHOP) chemotherapy improves response in a CHOP-resistant human diffuse large cell lymphoma xenograft model
-
Mohammad RM, Wall NR, Dutcher JA, Al-Katib AM. The addition of bryostatin 1 to cyclophosphamide, doxorubicin, vincristine, and prednisone (CHOP) chemotherapy improves response in a CHOP-resistant human diffuse large cell lymphoma xenograft model. Clin Cancer Res. 2000;6 (12):4950-6.
-
(2000)
Clin Cancer Res
, vol.6
, Issue.12
, pp. 4950-4956
-
-
Mohammad, R.M.1
Wall, N.R.2
Dutcher, J.A.3
Al-Katib, A.M.4
-
25
-
-
0035877590
-
Regulation of nuclear localization during signaling
-
Cyert MS. Regulation of nuclear localization during signaling. J Biol Chem. 2001;276(24): 20805-8.
-
(2001)
J Biol Chem
, vol.276
, Issue.24
, pp. 20805-20808
-
-
Cyert, M.S.1
-
26
-
-
77949659052
-
MDM2 inhibitor MI-319 in combination with cisplatin is an effective treatment for pancreatic cancer independent of p53 function
-
Azmi AS, Aboukameel A, Banerjee S, Wang Z, Mohammad M, Wu J, et al. MDM2 inhibitor MI-319 in combination with cisplatin is an effective treatment for pancreatic cancer independent of p53 function. Eur J Cancer. 2010;46(6):1122-31.
-
(2010)
Eur J Cancer
, vol.46
, Issue.6
, pp. 1122-1131
-
-
Azmi, A.S.1
Aboukameel, A.2
Banerjee, S.3
Wang, Z.4
Mohammad, M.5
Wu, J.6
-
27
-
-
79952578312
-
Nuclear pore complex: Biochemistry and biophysics of nucleocytoplasmic transport in health and disease
-
Jamali T, Jamali Y, Mehrbod M, Mofrad MR. Nuclear pore complex: biochemistry and biophysics of nucleocytoplasmic transport in health and disease. Int Rev Cell Mol Biol. 2011;287:233-86.
-
(2011)
Int Rev Cell Mol Biol
, vol.287
, pp. 233-286
-
-
Jamali, T.1
Jamali, Y.2
Mehrbod, M.3
Mofrad, M.R.4
-
29
-
-
4644278442
-
Karyopherins: From nuclear-transport mediators to nuclear-function regulators
-
Mosammaparast N, Pemberton LF. Karyopherins: from nuclear-transport mediators to nuclear-function regulators. Trend Cell Biology. 2004;14(10):547-56.
-
(2004)
Trend Cell Biology
, vol.14
, Issue.10
, pp. 547-556
-
-
Mosammaparast, N.1
Pemberton, L.F.2
-
30
-
-
0032901751
-
Disrupted p53 function as predictor of treatment failure and poor prognosis in B- and T-cell non- Hodgkin's lymphoma
-
Moller MB, Gerdes AM, Skjodt K, Mortensen LS, Pedersen NT. Disrupted p53 function as predictor of treatment failure and poor prognosis in B- and T-cell non- Hodgkin's lymphoma. Clin Cancer Res. 1999;5(5):1085-91.
-
(1999)
Clin Cancer Res
, vol.5
, Issue.5
, pp. 1085-1091
-
-
Moller, M.B.1
Gerdes, A.M.2
Skjodt, K.3
Mortensen, L.S.4
Pedersen, N.T.5
-
31
-
-
0030985459
-
Exportin 1 (Crm1p) is an essential nuclear export factor
-
Stade K, Ford CS, Guthrie C, Weis K. Exportin 1 (Crm1p) is an essential nuclear export factor. Cell. 1997;90(6):1041-50.
-
(1997)
Cell
, vol.90
, Issue.6
, pp. 1041-1050
-
-
Stade, K.1
Ford, C.S.2
Guthrie, C.3
Weis, K.4
-
32
-
-
0033529866
-
Leptomycin B inactivates CRM1/exportin 1 by covalent modification at a cysteine residue in the central conserved region
-
Kudo N, Matsumori N, Taoka H, Fujiwara D, Schreiner EP, Wolff B, et al. Leptomycin B inactivates CRM1/exportin 1 by covalent modification at a cysteine residue in the central conserved region. Proc Natl Acad Sci USA. 1999;96(16):9112-7.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, Issue.16
, pp. 9112-9117
-
-
Kudo, N.1
Matsumori, N.2
Taoka, H.3
Fujiwara, D.4
Schreiner, E.P.5
Wolff, B.6
-
33
-
-
4444226528
-
The epidemiology of non-Hodgkin's lymphoma
-
Fisher SG, Fisher RI. The epidemiology of non-Hodgkin's lymphoma. Oncogene. 2004;23(38):6524-34.
-
(2004)
Oncogene
, vol.23
, Issue.38
, pp. 6524-6534
-
-
Fisher, S.G.1
Fisher, R.I.2
-
34
-
-
72549094296
-
An MDM2 antagonist (MI-319) restores p53 functions and increases the life span of orally treated follicular lymphoma bearing animals
-
Mohammad RM. Wu J, Azmi AS, Aboukameel A, Sosin A, Wu S, et al. An MDM2 antagonist (MI-319) restores p53 functions and increases the life span of orally treated follicular lymphoma bearing animals. Mol Cancer. 2009;8:115.
-
(2009)
Mol Cancer
, vol.8
, pp. 115
-
-
Mohammad, R.M.1
Wu, J.2
Azmi, A.S.3
Aboukameel, A.4
Sosin, A.5
Wu, S.6
|