Endometriosis and cancer: What do we know?

Minerva Ginecologica

Volumn 65, Issue 2, 2013, Pages 167-179

  Nassif, J ^a   Mattar, S ^a   Abu Musa, A ^a   Eid, A ^a  

^a AMERICAN UNIVERSITY OF BEIRUT   (Lebanon)

Author keywords

Endometriosis; Genetics; Histology; Molecular mechanisms of pharmacological action

Indexed keywords

CA 125 ANTIGEN; CHEMOKINE RECEPTOR CXCR3; CYCLOOXYGENASE 2; EPITHELIAL MEMBRANE ANTIGEN; ESTRADIOL; ESTROGEN; ESTROGEN RECEPTOR ALPHA; FIBROBLAST GROWTH FACTOR 2; HEME; HEPATOCYTE NUCLEAR FACTOR 1BETA; INTERLEUKIN 1; INTERLEUKIN 1BETA; IRON; K RAS PROTEIN; KI 67 ANTIGEN; MACROPHAGE MIGRATION INHIBITION FACTOR; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROSTAGLANDIN E2; PROTEIN CDC42; PROTEIN P53; REACTIVE OXYGEN METABOLITE; TRANSFORMING GROWTH FACTOR BETA; VASCULOTROPIN;

BREAST CANCER; CANCER GROWTH; CANCER SURVIVAL; CARCINOGENESIS; CLINICAL EXAMINATION; DISEASE ASSOCIATION; DYSMENORRHEA; DYSPAREUNIA; ECHOGRAPHY; ENDOMETRIOSIS; ENDOMETRIUM TUMOR; FEMALE INFERTILITY; GYNECOLOGIC CANCER; HISTOPATHOLOGY; HUMAN; HYPERPLASIA; INFLAMMATION; LAPAROSCOPY; MENARCHE; MOLECULAR GENETICS; NUCLEAR MAGNETIC RESONANCE IMAGING; OVARY CANCER; PARITY; PELVIS PAIN SYNDROME; REVIEW; RISK FACTOR; SINGLE NUCLEOTIDE POLYMORPHISM; TUMOR INVASION;

ENDOMETRIOSIS; FEMALE; GENITAL DISEASES, FEMALE; GENITAL NEOPLASMS, FEMALE; HUMANS; OVARIAN DISEASES; OVARIAN NEOPLASMS;

EID: 84879559586     PISSN: 00264784     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (31)

1. Mann S, Patel P, Matthews CM, Pinto K, O'Connor J. Malignant transformation of endometriosis within the urinary bladder. Proc Bayl Univ Med Cent 2012;25:293-5.
2. Toki T, Fujii S, Silverberg SG. A clinicopathologic study on the association of endometriosis and carcinoma of the ovary using a scoring system. Int J Gynecol Cancer 1996;6:68-75. (Pubitemid 26076501)
3. Eržen M, Rakar S, Klančnik B, Syrjänen K. Endometriosis-associated ovarian carcinoma (EAOC): an entity distinct from other ovarian carcinomas as suggested by a nested case-control study. Gynecol Oncol 2001;83:100-8.
4. Van Gorp T, Amant F, Neven P, Vergote I. Endometriosis and the development of malignant tumors of the pelvis. A review of literature. Best Pract Res Clin Obstet Gynaecol 2004;18:349-71. (Pubitemid 38786637)
5. Vercellini P, Somigliana E, Buggio L, Bolis G, Fedele L. Endometriosis and ovarian cancer. Lancet Oncol 2012;13:e188-9.
6. Brinton LA, Gridley G, Persson I, Baron J, Bergqvist A. Cancer risk after a hospital discharge diagnosis of endometriosis. Am J Obstet Gynecol 1997;176:572-9. (Pubitemid 27147164)
7. Melin A, Sparen P, Persson I, Bergqvist A. Endometriosis and the risk of cancer with special emphasis on ovarian cancer. Hum Reprod 2000;21:1237-42.
8. Melin A, Sparen P, Bergqvist A. The risk of cancer and the role of parity among women with endometriosis. Hum Reprod 2007;22:3021-6. (Pubitemid 351696799)
9. Borgfeldt C, Andolf E. Cancer risk after hospital discharge diagnosis of benign ovarian cysts and endometriosis. Acta Obstet Gynecol Scan 2004;83:395-400. (Pubitemid 38406822)
10. Munksgaard PS, Blaakaer J. The association between endometriosis and gynecological cancers and breast cancer: A review of epidemiological data. Gynecol Oncol 2011;123;157-63.
11. Munksgaard PS, Blaakaer J. The association between endometriosis and ovarian cancer: A review of histological, genetic and molecular alterations. Gynecol Oncol 2012;124:164-9.
12. Wei JJ, William J, Bulun S. Endometriosis and Ovarian Cancer: A Review of Clinical, Pathologic, and Molecular Aspects. Int J Gynecol Pathol 2011;30:553-68.
13. Somigliana E, Viganò P, Parazzini F, Stoppelli S, Giambattista E, Vercellini P. Association between endometriosis and cancer: a comprehensive review and a critical analysis of clinical and epidemiological evidence. Gynecol Oncol 2006;101:331-41. (Pubitemid 44262088)
14. Pearce CL, Templeman C, Rossing MA, Lee A, Near AM, Webb PM et al. Association between endometriosis and risk of histological subtypes of ovarian cancer: a pooled analysis of case-control studies. Lancet Oncol 2012;13:385-94.
15. Gourley C. Link between endometriosis and ovarian-cancer subtypes. Lancet Oncol 2012;13:326-8.
16. Terada T. No evidence of endometriosis within serous and mucinous tumors of the ovary. Int J Clin Exp Pathol 2012;5:140-2.
17. Kajihara H, Yamada Y, Shigetomi H, Higashiura Y, Kobayashi H. The dichotomy in the histogenesis of endometriosis-associated ovarian cancer: clear cell-type versus endometrioid-type adenocarcinoma. Int J Gynecol Pathol 2012;31:304-12.
18. Canet B, Pons C, Espinosa I, Prat J. CDC42-positive macrophages may prevent malignant transformation of ovarian endometriosis. Hum Pathol 2012;43:720-5.
19. Furuya M, Tanaka R, Miyagi E, Kami D, Nagahama K, Miyagi Y et al. Impaired CXCL4 expression in tumor-associated macrophages (TAMs) of ovarian cancers arising in endometriosis. Cancer Biol Ther 2012;13:671-80.
20. Falconer H, Sundqvist J, Xu H, Vodolazkaia A, Fassbender A, Kyama C et al. Analysis of common variations in tumor suppressor genes on chr1p36 among Caucasian women with endometriosis. Gynecol Oncol 2012;127:398-402.
21. Yamamoto S, Tsuda H, Takano M, Iwaya K, Tamai S, Matsubara O. PIK3CA mutation is an early event in the development of endometriosis-associated ovarian clear cell adenocarcinoma. J Pathol 2011;225:189-94.
22. Martini M, Ciccarone M, Garganese G, Maggiore C, Evangelista A, Rahimi S et al. Possible involvement of hMLH1, p16(INK4a) and PTEN in the malignant transformation of endometriosis. Int J Cancer 2002;102:398-406. (Pubitemid 35265880)
23. Dinulescu DM, Ince TA, Quade BJ, Shafer SA, Crowley D, Jacks T. Role of K-ras and Pten in the development of mouse models of endometriosis and endometrioid ovarian cancer. Nat Med 2005;11:63-70. (Pubitemid 40215839)
24. Sato N, Tsunoda H, Nishida M, Morishita Y, Takimoto Y, Kubo T et al. Loss of heterozygosity on 10q23.3 and mutation of the tumor suppressor gene PTEN in benign endometrial cyst of the ovary: possible sequence progression from benign endometrial cyst to endometrioid carcinoma and clear cell carcinoma of the ovary. Cancer Res 2000;60:7052-6. (Pubitemid 32059184)
25. Akita K, Yoshida S, Ikehara Y, Shirakawa S, Toda M, Inoue M et al. Different levels of Sialyl-Tn antigen expressed on MUC16 in patients with endometriosis and ovarian cancer. Int J Gynecol Cancer 2012;22:531-8.
26. Prefumo F, Todeschini F, Fulcheri E, Venturini PL. Epithelial abnormalities in cystic ovarian endometriosis. Gynecol Oncol 2002;84:280-4. (Pubitemid 34136780)
27. Czernobilsky B, Morris WJ. A histologic study of ovarian endometriosis with emphasis on hyperplastic and atypical changes. Obstet Gynecol 1979;53;318-23. (Pubitemid 9110954)
28. Thomas EJ, Campbell IG. Molecular genetic defects in endometriosis. Gynecol Obstet Invest 2000;50(1 Suppl 1):44-50.
29. Mayr D, Amann G, Siefert C, Diebold J, Anderegg B. Does endometriosis really have premalignant potential? A clonal analysis of laser-microdissected tissue. FASEB J 2003;17:693-5.
30. Higuchi M, Yamaura T, Kanno R, Suzuki H, Asano S, Gotoh M. Incidental early lung adenocarcinoma after surgery for catamenial pneumothorax. Fukushima J Med Sci 2012;58:74-7.
31. Viganò P, Somigliana E, Parazzini F, Vercellini P. Bias versus causality: interpreting recent evidence of association between endometriosis and ovarian cancer. Fertil Steril 2007;88:588-93.