Formulation and evaluation of mucoadhesive buccal films impregnated with carvedilol nanosuspension: A potential approach for delivery of drugs having high first-pass metabolism

Drug Delivery

Volumn 20, Issue 5, 2013, Pages 224-235

  Rana, Priyanka ^a   Murthy, R S R ^a  

^a ISF COLLEGE OF PHARMACY   (India)

Author keywords

Bioavailability; Buccal delivery; Carvedilol; Ethyl cellulose; HPMC

Indexed keywords

ALGINIC ACID; CARBOMER; CARCA 625; CARVEDILOL; ETHYL CELLULOSE; HYDROXY PROPYL METHYL CELLULOSE; METHYLCELLULOSE; NANOCRYSTAL; NANOFILM; PENETRATION ENHANCING AGENT; PLASTICIZER; POLYMER; POLYVINYL ALCOHOL; POVIDONE; SODIUM CARBOXY METHYL CELLULOSE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; AREA UNDER THE CURVE; ARTICLE; BLOOD SAMPLING; CHEEK MUCOSA; COMPARATIVE STUDY; CONTROLLED STUDY; DISSOLUTION; DRUG BIOAVAILABILITY; DRUG DELIVERY SYSTEM; DRUG DISTRIBUTION; DRUG FORMULATION; DRUG PENETRATION; DRUG RELEASE; DRUG SCREENING; EX VIVO STUDY; FILM COATING; FIRST PASS EFFECT; GEL; HYPERTENSION; IN VITRO STUDY; IN VIVO STUDY; LIVER METABOLISM; LONG TERM CARE; MAXIMUM PLASMA CONCENTRATION; MORPHOLOGY; MUCOADHESION; MUCOADHESIVE BUCCAL FILM; NONHUMAN; PARTICLE SIZE; PHOTON CORRELATION SPECTROSCOPY; POLYMERIZATION; PRECIPITATION; PRIORITY JOURNAL; RABBIT; RAT; SCANNING ELECTRON MICROSCOPY; SURFACE CHARGE; TABLET FORMULATION; TIME TO MAXIMUM PLASMA CONCENTRATION; ZETA POTENTIAL;

ADHESIVENESS; ADMINISTRATION, BUCCAL; ANIMALS; ANTIHYPERTENSIVE AGENTS; CARBAZOLES; CHEMISTRY, PHARMACEUTICAL; DRUG DELIVERY SYSTEMS; PARTICLE SIZE; PERMEABILITY; PROPANOLAMINES; RABBITS; SOLUBILITY; SUSPENSIONS; SWINE;

EID: 84879557106     PISSN: 10717544     EISSN: 15210464     Source Type: Journal    
DOI: 10.3109/10717544.2013.779331     Document Type: Article

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