Metabolically obese status with normal weight is associated with both the prevalence and severity of angiographic coronary artery disease

Metabolism: Clinical and Experimental

Volumn 62, Issue 7, 2013, Pages 952-960

  Kwon, Beom June ^a   Kim, Dae Won ^a   Her, Sung Ho ^a   Kim, Dong Bin ^a   Jang, Sung Won ^a   Cho, Eun Joo ^a   Ihm, Sang Hyun ^a   Kim, Hee Yeol ^a   Youn, Ho Joong ^a   Seung, Ki Bae ^a   Kim, Jae Hyung ^a   Rho, Tai Ho ^a  

^a The Catholic University of Korea   (South Korea)

Author keywords

Coronary artery disease; Metabolically obese but normal weight; Obesity

Indexed keywords

ANTIANGINA PECTORIS AGENT; ANTITHROMBOCYTIC AGENT; C REACTIVE PROTEIN;

ADULT; AGE; AGED; ARTICLE; CONTROLLED STUDY; CORONARY ARTERY DISEASE; DIABETES MELLITUS; DISEASE ASSOCIATION; DISEASE SEVERITY; FEMALE; GENSINI SCORE; GLOMERULUS FILTRATION RATE; HUMAN; MAJOR CLINICAL STUDY; MALE; OBESITY; PRIORITY JOURNAL; SEX DIFFERENCE; SMOKING;

AGED; BODY MASS INDEX; CORONARY ARTERY DISEASE; CORONARY VESSELS; CROSS-SECTIONAL STUDIES; DIABETES MELLITUS, TYPE 2; ENERGY METABOLISM; FEMALE; HUMANS; MALE; METABOLIC DISEASES; MIDDLE AGED; OBESITY; OVERWEIGHT; PREVALENCE; REPUBLIC OF KOREA; RISK FACTORS; SEVERITY OF ILLNESS INDEX;

EID: 84879552732     PISSN: 00260495     EISSN: 15328600     Source Type: Journal    
DOI: 10.1016/j.metabol.2013.01.006     Document Type: Article

References (49)

1. B.P. Mulhall, J.P. Ong, and Z.M. Younossi Non-alcoholic fatty liver disease: an overview J Gastroenterol Hepatol 17 11 2002 1136 1143
2. D.W. Haslam, and W.P. James Obesity Lancet 366 9492 2005 1197 1209
3. D.C. Lau, J.D. Douketis, and K.M. Morrison 2006 Canadian clinical practice guidelines on the management and prevention of obesity in adults and children [summary] CMAJ 176 8 2007 S1 S13
4. G.M. Reaven Banting lecture 1988. Role of insulin resistance in human disease Diabetes 37 12 1988 1595 1607
5. E.A. Sims Are there persons who are obese, but metabolically healthy? Metabolism 50 12 2001 1499 1504
6. A.D. Karelis Metabolically healthy but obese individuals Lancet 372 9646 2008 1281 1283
7. A.D. Karelis, M. Faraj, and J.P. Bastard The metabolically healthy but obese individual presents a favorable inflammation profile J Clin Endocrinol Metab 90 7 2005 4145 4150
8. C.A. Aguilar-Salinas, E.G. Garcia, and L. Robles High adiponectin concentrations are associated with the metabolically healthy obese phenotype J Clin Endocrinol Metab 93 10 2008 4075 4079
9. L.A. Lynch, J.M. O'Connell, and A.K. Kwasnik Are natural killer cells protecting the metabolically healthy obese patient? Obesity (Silver Spring) 17 3 2009 601 605
10. K.E. Kip, O.C. Marroquin, and D.E. Kelley Clinical importance of obesity versus the metabolic syndrome in cardiovascular risk in women: a report from the Women's Ischemia Syndrome Evaluation (WISE) study Circulation 109 6 2004 706 713
11. A.C. St-Pierre, B. Cantin, and P. Mauriege Insulin resistance syndrome, body mass index and the risk of ischemic heart disease CMAJ 172 10 2005 1301 1305
12. P.T. Katzmarzyk, I. Janssen, and R. Ross The importance of waist circumference in the definition of metabolic syndrome: prospective analyses of mortality in men Diabetes Care 29 2 2006 404 409
13. J.B. Meigs, P.W. Wilson, and C.S. Fox Body mass index, metabolic syndrome, and risk of type 2 diabetes or cardiovascular disease J Clin Endocrinol Metab 91 8 2006 2906 2912
14. R.P. Wildman, P. Muntner, and K. Reynolds The obese without cardiometabolic risk factor clustering and the normal weight with cardiometabolic risk factor clustering: prevalence and correlates of 2 phenotypes among the US population (NHANES 1999-2004) Arch Intern Med 168 15 2008 1617 1624
15. R.C. Weisell Body mass index as an indicator of obesity Asia Pac J Clin Nutr 11 Suppl 8 2002 S681 S684
16. M.P. St-Onge, I. Janssen, and S.B. Heymsfield Metabolic syndrome in normal-weight Americans: new definition of the metabolically obese, normal-weight individual Diabetes Care 27 9 2004 2222 2228
17. K. Lee Metabolically obese but normal weight (MONW) and metabolically healthy but obese (MHO) phenotypes in Koreans: characteristics and health behaviors Asia Pac J Clin Nutr 18 2 2009 280 284
18. M.C. Kim, C.S. Kim, and T.H. Chung MONW phenotype is associated with advanced colorectal adenoma in Korean men Obesity (Silver Spring) 20 9 2012 1876 1881
19. F.B. Ortega, D.C. Lee, and P.T. Katzmarzyk The intriguing metabolically healthy but obese phenotype: cardiovascular prognosis and role of fitness Eur Heart J 2012 [e-publish]
20. S.Y. Lee, H.S. Park, and D.J. Kim Appropriate waist circumference cutoff points for central obesity in Korean adults Diabetes Res Clin Pract 75 1 2007 72 80
21. Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III) final report Circulation 106 25 2002 3143 3421
22. A.S. Levey, J.P. Bosch, and J.B. Lewis A more accurate method to estimate glomerular filtration rate from serum creatinine: a new prediction equation. Modification of Diet in Renal Disease Study Group Ann Intern Med 130 6 1999 461 470
23. G.G. Gensini A more meaningful scoring system for determining the severity of coronary heart disease Am J Cardiol 51 3 1983 606
24. F. Conus, R. Rabasa-Lhoret, and F. Peronnet Characteristics of metabolically obese normal-weight (MONW) subjects Appl Physiol Nutr Metab 32 1 2007 4 12
25. R. Kelishadi, S.R. Cook, and M.E. Motlagh Metabolically obese normal weight and phenotypically obese metabolically normal youths: the CASPIAN Study J Am Diet Assoc 108 1 2008 82 90
26. A. Romero-Corral, V.K. Somers, and J. Sierra-Johnson Normal weight obesity: a risk factor for cardiometabolic dysregulation and cardiovascular mortality Eur Heart J 31 6 2010 737 746
27. J.Y. Kim, H.S. Mun, and B.K. Lee Impact of metabolic syndrome and its individual components on the presence and severity of angiographic coronary artery disease Yonsei Med J 51 5 2010 676 682
28. W. Kosmala, D. Jedrzejuk, and R. Derzhko Left ventricular function impairment in patients with normal-weight obesity: contribution of abdominal fat deposition, profibrotic state, reduced insulin sensitivity, and proinflammatory activation Circ Cardiovasc Imaging 5 3 2012 349 356
29. C. Voulgari, N. Tentolouris, and P. Dilaveris Increased heart failure risk in normal-weight people with metabolic syndrome compared with metabolically healthy obese individuals J Am Coll Cardiol 58 13 2011 1343 1350
30. K.G. Alberti, R.H. Eckel, and S.M. Grundy Harmonizing the metabolic syndrome: a joint interim statement of the International Diabetes Federation Task Force on Epidemiology and Prevention; National Heart, Lung, and Blood Institute; American Heart Association; World Heart Federation; International Atherosclerosis Society; and International Association for the Study of Obesity Circulation 120 16 2009 1640 1645
31. E.S. Ford The metabolic syndrome and mortality from cardiovascular disease and all-causes: findings from the National Health and Nutrition Examination Survey II Mortality Study Atherosclerosis 173 2 2004 309 314
32. F. Hadaegh, R. Mohebi, and L. Cheraghi Do different metabolic syndrome definitions predict cerebrovascular events and coronary heart disease independent of their components?: 9 years follow-up of the Tehran lipid and glucose study Stroke 43 6 2012 1669 1671
33. W. Zheng, D.F. McLerran, and B. Rolland Association between body-mass index and risk of death in more than 1 million Asians N Engl J Med 364 8 2011 719 729
34. G. Calori, G. Lattuada, and L. Piemonti Prevalence, metabolic features, and prognosis of metabolically healthy obese Italian individuals: the Cremona Study Diabetes Care 34 1 2011 210 215
35. Beck, E., N. Esser, N. Paquot, et al. [Metabolically obese normal-weight individuals and metabolically healthy, but obese, subjects]. Rev Med Suisse 2009;5(214):1644-6, 8-9.
36. M.C. Pouliot, J.P. Despres, and S. Lemieux Waist circumference and abdominal sagittal diameter: best simple anthropometric indexes of abdominal visceral adipose tissue accumulation and related cardiovascular risk in men and women Am J Cardiol 73 7 1994 460 468
37. S. Yusuf, S. Hawken, and S. Ounpuu Obesity and the risk of myocardial infarction in 27,000 participants from 52 countries: a case-control study Lancet 366 9497 2005 1640 1649
38. L. de Koning, A.T. Merchant, and J. Pogue Waist circumference and waist-to-hip ratio as predictors of cardiovascular events: meta-regression analysis of prospective studies Eur Heart J 28 7 2007 850 856
39. J.C. Seidell, T.S. Han, and E.J. Feskens Narrow hips and broad waist circumferences independently contribute to increased risk of non-insulin-dependent diabetes mellitus J Intern Med 242 5 1997 401 406
40. J.C. Seidell, L. Perusse, and J.P. Despres Waist and hip circumferences have independent and opposite effects on cardiovascular disease risk factors: the Quebec Family Study Am J Clin Nutr 74 3 2001 315 321
41. X. Zhang, X.O. Shu, and G. Yang Abdominal adiposity and mortality in Chinese women Arch Intern Med 167 9 2007 886 892
42. T. Pischon, H. Boeing, and K. Hoffmann General and abdominal adiposity and risk of death in Europe N Engl J Med 359 20 2008 2105 2120
43. B.L. Heitmann, P. Frederiksen, and L. Lissner Hip circumference and cardiovascular morbidity and mortality in men and women Obes Res 12 3 2004 482 487
44. N. Ruderman, D. Chisholm, and X. Pi-Sunyer The metabolically obese, normal-weight individual revisited Diabetes 47 5 1998 699 713
45. M. Fogelholm, and W. van Marken Lichtenbelt comparison of body composition methods: a literature analysis Eur J Clin Nutr 51 8 1997 495 503
46. R.R. Azar, G. Aoun, and D.B. Fram Relation of C-reactive protein to extent and severity of coronary narrowing in patients with stable angina pectoris or abnormal exercise tests Am J Cardiol 86 2 2000 205 207
47. J.S. Zebrack, J.B. Muhlestein, and B.D. Horne C-reactive protein and angiographic coronary artery disease: independent and additive predictors of risk in subjects with angina J Am Coll Cardiol 39 4 2002 632 637
48. N. Rifai High-sensitivity C-reactive protein: a useful marker for cardiovascular disease risk prediction and the metabolic syndrome Clin Chem 51 3 2005 504 505
49. Appropriate body-mass index for Asian populations and its implications for policy and intervention strategies Lancet 363 9403 2004 157 163