A subset of anti-rotavirus antibodies directed against the viral protein VP7 predicts the onset of celiac disease and induces typical features of the disease in the intestinal epithelial cell line T84

Immunologic Research

Volumn 56, Issue 2-3, 2013, Pages 465-476

  Dolcino, Marzia ^a   Zanoni, Giovanna ^b   Bason, Caterina ^c   Tinazzi, Elisa ^c   Boccola, Elisa ^b   Valletta, Enrico ^b   Contreas, Giovanna ^b   Lunardi, Claudio ^c   Puccetti, Antonio ^a,d  

^a G GASLINI INSTITUTE   (Italy)

^b UNIVERSITY OF VERONA   (Italy)

^c UNIVERSITY OF VERONA   (Italy)

^d UNIVERSITY OF GENOA   (Italy)

Author keywords

Autoantibodies; Celiac disease; Gene expression; Rotavirus

Indexed keywords

IMMUNOGLOBULIN A ANTIBODY; VIRUS PROTEIN;

ADULT; ARTICLE; CELIAC DISEASE; CHILD; CLINICAL FEATURE; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN CELL; INFANT; INSULIN DEPENDENT DIABETES MELLITUS; INTESTINE EPITHELIUM CELL; MAJOR CLINICAL STUDY; MALE; MOLECULAR MIMICRY; NUCLEOTIDE SEQUENCE; PRESCHOOL CHILD; PRIORITY JOURNAL; PROSPECTIVE STUDY; ROTAVIRUS INFECTION; SCHOOL CHILD;

ADOLESCENT; ADULT; ANTIBODIES, VIRAL; ANTIGENS, VIRAL; APOPTOSIS; CAPSID PROTEINS; CELIAC DISEASE; CELL LINE; CHILD; CHILD, PRESCHOOL; CROSS REACTIONS; DIABETES MELLITUS, TYPE 1; FEMALE; HUMANS; IMMUNOGLOBULIN A; INFANT; INTESTINAL MUCOSA; MALE; MOLECULAR MIMICRY; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PREDICTIVE VALUE OF TESTS; PROGNOSIS; ROTAVIRUS INFECTIONS; TRANSGLUTAMINASES; YOUNG ADULT;

EID: 84879551944     PISSN: 0257277X     EISSN: 15590755     Source Type: Journal    
DOI: 10.1007/s12026-013-8420-0     Document Type: Article

References (33)

1. Rewers M. Epidemiology of celiac disease: what are the prevalence, incidence, and progression of celiac disease? Gastroenterology. 2005;128:S47-51. (Pubitemid 40460821)
2. Sollid LM. Celiac disease: dissecting a complex inflammatory disorder. Nat Rev Immunol. 2002;2:647-55. (Pubitemid 37328722)
3. Lunardi C, Bason C, Navone R, Millo E, Damonte G, Corrocher R, et al. Systemic sclerosis immunoglobulin G autoantibodies bind the human cytomegalovirus late protein UL94 and induce apoptosis in human endothelial cells. Nat Med. 2000;6:1183-6.
4. Lunardi C, Bason C, Leandri M, Navone R, Lestani M, Millo E, et al. Autoantibodies to inner ear and endothelial antigens in Cogan's syndrome. Lancet. 2002;360:915-21. (Pubitemid 35283836)
5. Navone R, Lunardi C, Gerli R, Tinazzi E, Peterlana D, Bason C, et al. Identification of tear lipocalin as a novel autoantigen target in Sjögren's syndrome. J Autoimmun. 2005;25:229-34. (Pubitemid 41654468)
6. Puccetti A, Bason C, Simeoni S, Millo E, Tinazzi E, Beri R, et al. In chronic idiopathic urticaria autoantibodies against Fc epsilonRII/CD23 induce histamine release via eosinophil activation. Clin Exp Allergy. 2005;35:1599-607.
7. Zanoni G, Navone R, Lunardi C, Tridente G, Bason C, Sivori S, et al. In celiac disease, a subset of autoantibodies against transglutaminase binds toll-like receptor 4 and induces activation of monocytes. PLoS Med. 2006;3:e358. (Pubitemid 44455274)
8. Lindfors K, Mäki M, Kaukinen K. Transglutaminase 2-targeted autoantibodies in celiac disease: pathogenetic players in addition to diagnostic tools? Autoimmun Rev. 2010;9:744-9.
9. Stene LC, Honeyman MC, Hoffenberg EJ, Haas JE, Sokol RJ, Emery L, et al. Rotavirus infection frequency and risk of celiac disease autoimmunity in early childhood: a longitudinal study. Am J Gastroenterol. 2006;101:2333-40. (Pubitemid 44477562)
10. Kooy-Winkelaar Y, van Lummel M, Moustakas AK, Schweizer J, Mearin ML, Mulder CJ, et al. Gluten-specific T cells cross-react between HLA-DQ8 and the HLA-DQ2α/DQ8β transdimer. J Immunol. 2011;187:5123-9.
11. Waisbourd-Zinman O, Hojsak I, Rosenbach Y, Mozer-Glassberg Y, Shalitin S, Phillip M, Shamir R. Spontaneous normalization of anti-tissue transglutaminase antibody levels is common in children with type 1 diabetes mellitus. Dig Dis Sci. 2012;57:1314-20.
12. Volta U, Tovoli F, Caio G. Clinical and immunological features of celiac disease in patients with Type 1 diabetes mellitus. Expert Rev Gastroenterol Hepatol. 2011;5:479-87.
13. Salardi S, Volta U, Zucchini S, Fiorini E, Maltoni G, Vaira B, et al. Prevalence of celiac disease in children with type 1 diabetes mellitus increased in the mid-1990s: an 18-year longitudinal study based on anti-endomysial antibodies. J Pediatr Gastroenterol Nutr. 2008;46:612-4.
14. Gabriel S, Mihaela I, Angela B, Mariana A, Doru D. Prevalence of IgA antitissue transglutaminase antibodies in children with type 1 diabetes mellitus. J Clin Lab Anal. 2011;25:156-61.
15. Contreas G, Valletta E, Ulmi D, Cantoni S, Pinelli L. Screening of coeliac disease in North Italian children with type I diabetes: limited usefulness of HLA-DQ typing. Acta Paediatr. 2004;93:628-32. (Pubitemid 38570229)
16. Oberhuber G, Granditsch G, Vogelsang H. The histopathology of coeliac disease: time for a standardized report scheme for pathologists. Eur J Gastroenterol Hepatol. 1999;11:1185-94. (Pubitemid 30433773)
17. Wellings DA, Atherton E. Standard FMOC protocols. Meth Enzymol. 1997;289:44-67. (Pubitemid 27467242)
18. Katz S, Irizarry RA, Lin X, Tripputi M, Porter MW. A summarization approach for Affymetrix GeneChip data using a reference training set from a large, biologically diverse database. BMC Bioinformatics. 2006;. doi: 10.1186/1471-2105-7-464. (Pubitemid 44687884)
19. Diosdado B, van Oort E, Wijmenga C. "Coelionomics": towards understanding the molecular pathology of coeliac disease. Clin Chem Lab Med. 2005;43:685-95. (Pubitemid 41461171)
20. Ramsay RG, Malaterre J. Insights into c-Myb functions through investigating colonic crypts. Blood Cells Mol Dis. 2007;39:287-91. (Pubitemid 47484465)
21. Merlos-Suàrez A, Batlle E. Eph-ephrin signalling in adult tissue and cancer. Curr Opin Cell Biol. 2008;20:194-200.
22. Juuti-Uusitalo K, Mäki M, Kainulainen H, Isola J, Kaukinen K. Gluten affects epithelial differentiation-associated genes in small intestinal mucosa of coeliac patients. Clin Exp Immunol. 2007;150:294-305. (Pubitemid 47609574)
23. Bracken S, Byrne G, Kelly J, Jackson J, Feighery C. Altered gene expression in highly purified enterocytes from patients with active coeliac disease. BMC Genomics. 2008;. doi: 10.1186/1471-2164-9-377.
24. Zwiers A, Fuss IJ, Leijen S, Mulder CJ, Kraal G, Bouma G. Increased expression of the tight junction molecule claudin-18 A1 in both experimental colitis and ulcerative colitis. Inflamm Bowel Dis. 2008;14:1652-9.
25. Schulzke JD, Schulzke I, Fromm M, Riecken EO. Epithelial barrier and ion transport in coeliac sprue: electrical measurements on intestinal aspiration biopsy specimens. Gut. 1995;37:777-82.
26. Rocha F, Musch MW, Lishanskiy L, Bookstein C, Sugi K, Xie Y, et al. IFN-gamma downregulates expression of Na(+)/H(+) exchangers NHE2 and NHE3 in rat intestine and human Caco-2/bbe cells. Am J Physiol Cell Physiol. 2001;280:C1224-32.
27. Gill RK, Saksena S, Tyagi S, Alrefai WA, Malakooti J, Sarwar Z, et al. Serotonin inhibits Na +/H + exchange activity via 5-HT4 receptors and activation of PKC alpha in human intestinal epithelial cells. Gastroenterology. 2005;128:962-74. (Pubitemid 40523547)
28. Juuti-Uusitalo K, Mäki M, Kaukinen K, Collin P, Visakorpi T, Vihinen M, Kainulainen H. cDNA microarray analysis of gene expression in coeliac disease jejunal biopsy samples. J Autoimmun. 2004;22:249-65. (Pubitemid 38372193)
29. Benya RV, Matkowskyj KA, Danilkovich A, Hecht G. Galanin causes Cl- secretion in the human colon. Potential significance of inflammation-associated NF-kappa B activation on galanin-1 receptor expression and function. Ann N Y Acad Sci. 1998;863:64-77. (Pubitemid 29047764)
30. Diosdado B, Wapenaar MC, Franke L, Duran KJ, Goerres MJ, Hadithi M, et al. A microarray screen for novel candidate genes in coeliac disease pathogenesis. Gut. 2004;53:944-51. (Pubitemid 38824150)
31. Barone MV, Gimigliano A, Castoria G, Paolella G, Maurano F, Paparo F, et al. Growth factor-like activity of gliadin, an alimentary protein: implications for coeliac disease. Gut. 2007;56:480-8. (Pubitemid 46580502)
32. Ciccocioppo R, Di Sabatino A, Bauer M, Della Riccia DN, Bizzini F, Biagi F, et al. Matrix metalloproteinase pattern in celiac duodenal mucosa. Lab Invest. 2005;85:397-407. (Pubitemid 40333156)
33. Parks WC, Wilson CL, Lopez-Boado YS. Matrix metallo-proteinases as modulators of inflammation and innate immunity. Nat Rev Immunol. 2004;4:617-29. (Pubitemid 39025047)