Association of Body Iron Status with the Risk of Premature Acute Myocardial Infarction in a Pakistani Population

PLoS ONE

Volumn 8, Issue 6, 2013, Pages

  Iqbal, Mohammad Perwaiz ^a   Mehboobali, Naseema ^a   Tareen, Asal Khan ^b   Yakub, Mohsin ^a   Iqbal, Saleem Perwaiz ^a   Iqbal, Khalida ^a   Haider, Ghulam ^a  

^a AGA KHAN UNIVERSITY   (Pakistan)

^b NATIONAL INSTITUTE OF CARDIOVASCULAR DISEASES   (Pakistan)

Author keywords

[No Author keywords available]

Indexed keywords

CHOLESTEROL; CYANOCOBALAMIN; FERRITIN; FOLIC ACID; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; HOMOCYSTEINE; IRON; LEAD; LOW DENSITY LIPOPROTEIN CHOLESTEROL; SOLUBLE TRANSFERRIN RECEPTOR; TRANSFERRIN RECEPTOR; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

ACUTE HEART INFARCTION; ADULT; AGE; AMINO ACID BLOOD LEVEL; ARTICLE; BLOOD SAMPLING; BODY IRON STATUS; CARDIOVASCULAR RISK; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; CYANOCOBALAMIN BLOOD LEVEL; DIET RESTRICTION; DISEASE ACTIVITY; DISEASE ASSOCIATION; FEMALE; FERRITIN BLOOD LEVEL; FOLIC ACID BLOOD LEVEL; GENDER; HOMOCYSTEINE BLOOD LEVEL; HUMAN; IRON BALANCE; LEAD BLOOD LEVEL; MAJOR CLINICAL STUDY; MALE; ONSET AGE; PAKISTAN; PROTEIN BLOOD LEVEL; RISK ASSESSMENT; SOCIAL STATUS; TRIACYLGLYCEROL BLOOD LEVEL; VITAMIN BLOOD LEVEL;

ADULT; ASIAN CONTINENTAL ANCESTRY GROUP; CASE-CONTROL STUDIES; CHOLESTEROL; FEMALE; FERRITINS; FOLIC ACID; HUMANS; IRON; MALE; MYOCARDIAL INFARCTION; PAKISTAN; RECEPTORS, TRANSFERRIN; RISK; RISK FACTORS; TRIGLYCERIDES; VITAMIN B 12;

EID: 84879546742     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0067981     Document Type: Article

References (42)

1. Zegrean M, (2009) Association of body iron stores with development of cardiovascular disease in the adult population: a systematic review of the literature. Can J Cardiovasc Nurs 19(1): 26-32.
2. Tuomainen TP, Punnonen K, Nyyssönen K, Salonen JT, (1998) Association between body iron stores and the risk of acute myocardial infarction in men. Circulation 97: 1461-1466.
3. Jafar TH, Qadri Z, Chaturvedi N, (2008) Coronary artery disease epidemic in Pakistan: more electrocardiographic evidence of ischemia in women than in men. Heart 94(4): 408-413.
4. Silvia WD, Biswas S, Uthappa S, Shetty P, (2003) Ferritin, a potent threat for acute myocardial infarction? J Assoc Physicians India 51: 947-950.
5. Imtiaz S, Ahmad ZA, Naik S, Yasir M, Shah SMA, et al. (2009) Comparison of iron stores in healthy individuals and patients with ischaemic heart disease. Biomedica 25: 188-190.
6. Yakub M, Iqbal MP, (2010) Association of blood lead (Pb) and plasma homocysteine: A cross sectional survey in Karachi, Pakistan. PLoS ONE 5(7): e11706 doi:10.1371/journal.pone0011706.
7. Quadros E (2000) Vitamin B12. In: Song WO, Beecher GR, Eitenmiller RR, editors. Modern Analytical Methodologies in Fat and Water-Soluble Vitamins. Chemical Analysis Series.New York: John Wiley & Sons, Inc. 311-326.
8. Yusuf S, Hawken S, Ounpuu S, Dans T, Avezum A, et al. (2004) Effect of potentially modifiable risk factors associated with myocardial infarction in 52 countries (the INTERHEART study): case-control study. Lancet 364(9438): 937-952.
9. Iqbal MP, Shafiq M, Mehboobali N, Iqbal SP, Abbasi K, (2004) Variability in lipid profile in patients with acute myocardial infarction from two tertiary care hospitals in Pakistan. J Pak Med Assoc 54(11): 544-549.
10. Sullivan JL, (1981) Iron and the sex difference in heart disease risk. Lancet 1: 1293-1294.
11. Salonen JT, Nyyssonen K, Korpela H, Tuomilehto J, Seppanen R, et al. (1992) High stored iron levels are associated with excess risk of myocardial infarction in eastern Finnish men. Circulation 86: 803-811.
12. Salonen JT, Nyyssönen K, Salonen R, (1994) Body iron stores and risk of coronary heart disease. New Engl J Med 331: 1159-1160.
13. Kiechl S, Willeit J, Egger G, Poewe W, Oberhollenzer F, (1997) Body iron stores and the risk of carotid atherosclerosis: prospective results from the Bruneck Study. Circulation 96: 3300-3307.
14. Klipstein-Grobusch K, Koster JF, Grobbee DE, Lindemans J, Boeing H, et al. (1999) Serum ferritin and risk of myocardial infarction in the elderly: the Rotterdam Study. Am J Clin Nutr 69: 1231-1236.
15. Sempos CT, Looker AC, McGee DL, Rehm J (2010) Iron and heart disease: A review of epidemiological data. In: Yehuda S, Mostofski DI, editors. Iron deficiency and overload: from basic biology to clinical medicine. New York: Springer. 279-298.
16. van der A DL, Marx JJ, Grobbee DE, Kamphuis MH, Georgiou NA, et al. (2006) Non-transferrin-bound iron and risk of coronary heart disease in postmenopausal women. Circulation 113(16): 1942-1949.
17. Sun Q, Ma J, Rifai N, Franco OH, Rexrode KM, et al. (2008) Excessive body iron stores are not associated with risk of coronary heart disease in women. J Nutr 138(12): 2436-2441.
18. Sempos CT, Looker AC, Gillum RE, McGee DL, Vuong CV, et al. (2000) Serum ferritin and death from all causes and cardiovascular disease. The NHANESII Mortality Study. Ann Epidemiol 10: 441-448.
19. Knuiman MW, Divitini ML, Olynyk JK, Cullen DJ, Bartholomew HC, (2003) Ferritin and cardiovascular disease: A 17-year follow-up study in Busselton, Western Australia. Am J Epidemiol 158(2): 144-149 doi:10.1093/aje/kwg121.
20. Galan P, Noisette N, Estaquio C, Czernichow S, Mennen L, et al. (2006) Serum ferritin, cardiovascular risk factors, and ischaemic heart disease: a prospective analysis in the SU.VI. MAX (SUpplementation en VItamines et Mineraux AntioXydants) cohort. Public Health Nutr 9(1): 70-74.
21. Haidari M, Javadi E, Sanati A, Hajilooi M, Ghanbili J, (2001) Association of increased ferritin with premature coronary stenosis in men. Clin Chem 47(9): 1666-1672.
22. Bozzini C, Girelli D, Tinazzi E, Olivieri O, Stranieri C, et al. (2002) Biochemical and genetic markers of iron status and the risk of coronary artery disease: an angiongraphy-based study. Clin Chem 48(4): 622-628.
23. Auer J, Rammer M, Berent R, Weber T, Lassnig E, et al. (2002) Body iron stores and coronary atherosclerosis assessed by coronary angiography. Nutr Metab Cardiovasc Dis 12(5): 285-290.
24. Konijn AM, (1994) Iron metabolism in inflammation. Baillieres Clin Haematol 7(4): 829-849.
25. Feelders RA, Kuiper-Kramer EP, van Eijk HG, (1999) Structure, function and clinical significance of transferrin receptors. Clin Chem Lab Med 37(1): 1-10.
26. Saleheen D, Philippe F, (2004) CAD risk factors and acute myocardial infarction in Pakistan. Acta Cardiologica 59(4): 417-424.
27. Wazirali H, Ashfaque RA, Herzig JW, (2005) Association of blood group A with increased risk of coronary heart disease in the Pakistani population. Pak J Physiol 1: 25-27.
28. Iqbal R, Anand S, Ounpuu S, Islam S, Zhang X, et al. (2008) Dietary patterns and the risk of acute myocardial infarction in 52 countries: results of the INTERHEART study. Circulation 118(19): 1929-1937.
29. Yakub M, Iqbal MP, Iqbal R, (2010) Dietary patterns are associated with hyperhomocysteinemia in an urban Pakistani population. J Nutr 140: 1-6.
30. Iqbal MP, (2012) Lead pollution - A risk factor for cardiovascular disease in Asian developing countries. Pak J Pharm Sci 25(1): 289-294.
31. Zimmermann MB, Muthayya S, Moretti D, Kurpad A, Hurrell RF, (2006) Iron fortification reduces blood lead levels in children in Bangalore, India. Pediatrics 117(6): 2014-2021.
32. Menke A, Muntner P, Batuman V, Silbergeld EK, Guallar E, (2006) Blood lead below 0.48 micromol/L (10 microg/dL) and mortality among US adults. Circulation 114: 1388-1394.
33. Yakub M, Iqbal MP, Kakepoto GN, Rafique G, Memon Y, et al. (2010) High prevalence of mild hyperhomocysteinemia and folate, B12 and B6 deficiencies in an urban population in Karachi, Pakistan. Pak J Med Sci 26(4): 923-929.
34. Cooper D (2011) A list of foods high in iron content. Available: http://www.livestrong.com/article/25734-list-foods-high-iron-content/#ixzz2IKkMQUxe Accessed 2013 Jan 02.
35. Ghio AJ, Hilborn ED, Stonehuerner JG, Dailey LA, Carter JD, et al. (2008) Particulate matter in cigarette smoke alters iron homeostasis to produce a biological effect. Am J Respir Crit Care Med 178(11): 1130-1138.
36. Moroz C, Bessler H, Katz M, Zahavi I, Salman H, et al. (1997) Elevated serum ferritin level in acute myocardial infarction. Biomed Pharmacother 51(3): 126-130.
37. Braun S, Ndrepepa G, von Beckerath N, Vogt W, Schömig A, et al. (2004) Value of serum ferritin and soluble transferrin receptor for prediction of coronary artery disease and its clinical presentations. Atherosclerosis 174(1): 105-110.
38. Ghaffar A, Reddy KS, Singhi M, (2004) Burden of non-communicable diseases in South Asia. BMJ 328(7443): 807-810.
39. Sharma M, Ganguly NK, (2005) Premature coronary artery disease in Indians and its associated risk factors. Vasc Health Risk Manag 1(3): 217-225.
40. Xu J, Knutson MD, Carter CS, Leeuwenburgh C, (2008) Iron accumulation with age, oxidative stress and functional decline. PLoS ONE 3(8): e2865.
41. Porreca E, Ucchino S, Di Febbo C, Di Bartlomeo N, Angelucci D, et al. (1994) Antiproliferative effect of desferrioxamine on vascular smooth muscle cells in vitro and in vivo. Arterioscler Thromb 14(2): 299-304.
42. Iqbal SP, Dodani S, Qureshi R, (2004) Risk factors and behaviours for coronary artery disease (CAD) among ambulatory Pakistanis. J Pak Med Assoc 54: 261-266.