Malaria, clinical features and acute crisis in children suffering from sickle cell disease in resource-limited settings: A retrospective description of 90 cases

Pathogens and Global Health

Volumn 107, Issue 4, 2013, Pages 198-201

  Aloni, Michel Ntetani ^a,b   Tshimanga, Bertin Kadima ^a,b   Ekulu, Pépé Mfutu ^a,b   Ehungu, Jean Lambert Gini ^a,b   Ngiyulu, René Makwala ^a,b  

^a University of Kinshasa Hospital   (Congo)

^b UNIVERSITY OF KINSHASA   (Congo)

Author keywords

Children; Democratic republic of congo; Kinshasa; Malaria; Sickle cell disease

Indexed keywords

HEMOGLOBIN; QUININE;

ADOLESCENT; ARTICLE; BLOOD TRANSFUSION; CHILD; DEMOCRATIC REPUBLIC CONGO; DIGESTIVE SYSTEM FUNCTION DISORDER; FEMALE; GILBERT DISEASE; HAND FOOT SYNDROME; HEPATOMEGALY; HUMAN; INFANT; LETHARGY; MAJOR CLINICAL STUDY; MALARIA; MALARIA FALCIPARUM; MALE; PRESCHOOL CHILD; RESPIRATORY DISTRESS; RETICULOCYTOSIS; RETROSPECTIVE STUDY; SCHOOL CHILD; SICKLE CELL ANEMIA; SPLENOMEGALY;

ADOLESCENT; ANEMIA, SICKLE CELL; CHILD; CHILD, PRESCHOOL; DEMOCRATIC REPUBLIC OF THE CONGO; FEMALE; HUMANS; INFANT; MALARIA; MALE; RETROSPECTIVE STUDIES;

EID: 84879515261     PISSN: 20477724     EISSN: 20477732     Source Type: Journal    
DOI: 10.1179/2047773213Y.0000000089     Document Type: Article

References (10)

1. Modell B, Darlison M. Global epidemiology of haemoglobin disorders and derived service indicators. Bull World Health Organ. 2008;86:480-7.
2. Taylor SM, Messina JP, Hand CC, Juliano JJ, Muwonga J, Tshefu AK, et al. Molecular malaria epidemiology: mapping and burden estimates for the Democratic Republic of the Congo, 2007. PLoS One. 2011;6:e16420.
3. Vandepitte J, Motulosky AG. Abnormal haemoglobins in the Kasai province of the Belgian Congo. Nature. 1956;177:757.
4. Tshilolo L, Aissi LM, Lukusa D, Kinsiama C, Wembonyama S, Gulbis B, et al. Neonatal screening for sickle cell anemia in the Democratic Republic of Congo: experience from a pioneer project on 31 204 newborns. J Clin Pathol. 2009;62:35-8.
5. Messina JP, Taylor SM, Meshnick Linke SR AM, Tshefu AK, Atua B, et al. Population, behavioural and environmental drivers of malaria prevalence in the Democratic Republic of Congo. Malar J. 2011;10:161.
6. Tshilolo LM, Mukendi RK, Wembonyama SO. Blood transfusion rate in Congolese patients with sickle cell anemia. Indian J Pediatr. 2007;74:735-8.
7. McAuley CF, Webb C, Makani J, Macharia A, Uyoga S, Opi DH, et al. High mortality from Plasmodium falciparum malaria in children living with sickle cell anemia on the coast of Kenya. Blood. 2010;116:1663-8.
8. Diagne I, Soares GM, Gueye A, Diagne-Gueye NR, Fall L, N'Diaye O, et al. Infections in Senegalese children and adolescents with sickle cell anemia: epidemiological aspects. Dakar Med. 2000;45:55-8.
9. Ferreira A, Marguti I, Bechmann I, Jeney V, Chora A, Palha NR, et al. Sickle hemoglobin confers tolerance to Plasmodium infection. Cell. 2011;145:398-409.
10. Rosenthal PJ. Lessons from sickle cell disease in the treatment and control of malaria. N Engl J Med. 2011;364:2549-51.