Diagnosis of colon cancer differs in younger versus older patients despite similar complaints

Israel Medical Association Journal

Volumn 15, Issue 6, 2013, Pages 284-287

  Ben Ishay, Offir ^a   Brauner, Eran ^a   Peled, Zvi ^a   Othman, Amira ^a   Person, Benjamin ^a   Kluger, Yoram ^a  

^a TECHNION ISRAEL INSTITUTE OF TECHNOLOGY   (Israel)

Author keywords

Advanced staging; Colonic neoplasm; Diagnosis; Duration of symptoms; Young age

Indexed keywords

ADULT; AGE; AGED; ARTICLE; CANCER STAGING; COHORT ANALYSIS; COLON CANCER; CONTROLLED STUDY; DEMOGRAPHY; DISEASE DURATION; GENDER; HUMAN; INFORMATION PROCESSING; MAJOR CLINICAL STUDY; MALE; MORTALITY; OUTCOME ASSESSMENT; PATHOLOGY; RETROSPECTIVE STUDY;

ADENOCARCINOMA; ADULT; AGE FACTORS; AGED; AGED, 80 AND OVER; COLECTOMY; COLON; COLONIC NEOPLASMS; FEMALE; HUMANS; ISRAEL; LOGISTIC MODELS; MALE; MIDDLE AGED; MORTALITY; NEOPLASM STAGING; OUTCOME ASSESSMENT (HEALTH CARE); RETROSPECTIVE STUDIES; RISK FACTORS; SYMPTOM ASSESSMENT; TIME-TO-TREATMENT;

EID: 84879510207     PISSN: 15651088     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (21)

1. Jemal A, Siegel R, Ward E, Hao Y, Xu J, Thun MJ. Cancer statistics, 2009. CA Cancer J Clin 2009; 59 (4): 225-49. Epub 2009 May 27.
2. Ryan DP, Engelman JA, Ferrone CR, Sahani DV, Lisovsky M. Case records of the Massachusetts General Hospital. Case 19-2010. A 35-year-old man with adenocarcinoma of the cecum. N Engl J Med 2010; 362 (25): 2411-19.
3. Howlader N, Noone AM, Krapcho M, et al., eds. SEER Cancer Statistics Review, 1975-2008, National Cancer Institute. Bethesda, MD, http://seer.cancer.gov/csr/1975_2008/, based on November 2010 SEER data submission, posted to the SEER web site, 2011.
4. Ekbom A, Helmick C, Zack M, Adami HO. Ulcerative colitis and colorectal cancer. A population-based study. N Engl J Med 1990; 323 (18): 1228-33.
5. Ziogas A, Horick NK, Kinney AY, et al. Clinically relevant changes in family history of cancer over time. JAMA 2011; 306 (2): 172-8.
6. Friedenreich C, Norat T, Steindorf K, et al. Physical activity and risk of colon and rectal cancers: the European prospective investigation into cancer and nutrition. Cancer Epidemiol Biomarkers Prev 2006; 15 (12): 2398-407.
7. Wolin KY, Lee IM, Colditz GA, Glynn RJ, Fuchs C, Giovannucci E. Leisuretime physical activity patterns and risk of colon cancer in women. Int J Cancer 2007; 121 (12): 2776-81.
8. Slattery ML. Physical activity and colorectal cancer. Sports Med 2004; 34 (4): 239-52.
9. Morikawa T, Kuchiba A, Yamauchi M, et al. Association of CTNNB1 (betacatenin) alterations, body mass index, and physical activity with survival in patients with colorectal cancer. JAMA 2011; 305 (16): 1685-94.
10. Botteri E, Iodice S, Bagnardi V, Raimondi S, Lowenfels AB, Maisonneuve P. Smoking and colorectal cancer: a meta-analysis. JAMA 2008; 300 (23): 2765-78.
11. Giovannucci E. Modifiable risk factors for colon cancer. Gastroenterol Clin North Am 2002; 31 (4): 925-43.
12. Larsson SC, Wolk A. Meat consumption and risk of colorectal cancer: a metaanalysis of prospective studies. Int J Cancer 2006; 119 (11): 2657-64.
13. Zbuk K, Sidebotham EL, Bleyer A, La Quaglia MP. Colorectal cancer in young adults. Semin Oncol 2009; 36: 439-50.
14. Kapiteijn E, Liefers GJ, Los LC, et al. Mechanisms of oncogenesis in colon versus rectal cancer. J Pathol 2001; 195 (2): 171-8.
15. Union for International Cancer Control, TNM Classification of Malignant Tumors. 7th edn. New York: Springer, 2009.
16. Itah R, Greenberg R, Werbin N, Sacham-Shmueli E, Inbar R, Avital S. Current changes in the management and outcome of patients with curable colorectal cancer. IMAJ Isr Med Assoc J 2011; 13 (5): 300-3.
17. Morris M, Platell C, Iacopetta B. A population-based study of age-related variation in clinicopathological features, molecular markers and outcome from colorectal cancer. Anticancer Res 2007; 27 (4C): 2833-8.
18. Gonzalez EC, Roetzheim RG, Ferrante JM, Campbell R. Predictors of proximal vs. distal colorectal cancers. Dis Colon Rectum 2001; 44 (2): 251-8.
19. Liang JT, Huang KC, Cheng AL, Jeng YM, Wu MS, Wang SM. Clinicopathological and molecular biological features of colorectal cancer in patients less than 40 years of age. Br J Surg 2003; 90: 205-14.
20. Lin JT, Wang WS, Yen CC, et al. Outcome of colorectal carcinoma in patients under 40 years of age. J Gastroenterol Hepatol 2005; 6: 900-5.
21. O'Connell JB, Maggard MA, Livingston EH, Yo CK. Colorectal cancer in the young. Am J Surg 2004; 187: 343-8.