-
1
-
-
0036738035
-
Sildenafil augments the effect of inhaled nitric oxide for postoperative pulmonary hypertensive crises
-
12202882 10.1067/mtc.2002.125265
-
Atz AM, Lefler AK, Fairbrother DL et al (2002) Sildenafil augments the effect of inhaled nitric oxide for postoperative pulmonary hypertensive crises. J Thorac Cardiovasc Surg 124:628-629
-
(2002)
J Thorac Cardiovasc Surg
, vol.124
, pp. 628-629
-
-
Atz, A.M.1
Lefler, A.K.2
Fairbrother, D.L.3
-
2
-
-
67649632034
-
Diagnosis and assessment of pulmonary arterial hypertension
-
19555859 10.1016/j.jacc.2009.04.011
-
Badesch DB, Champion HC, Sanchez MA et al (2009) Diagnosis and assessment of pulmonary arterial hypertension. J Am Coll Cardiol 54(Suppl 1):S55-S66
-
(2009)
J Am Coll Cardiol
, vol.54
, Issue.SUPPL. 1
-
-
Badesch, D.B.1
Champion, H.C.2
Sanchez, M.A.3
-
3
-
-
79955845135
-
Pulmonary arterial hypertension and response to tadalafil (PHIRST) study group: Tadalafil monotherapy and as add-on to background bosentan in patients with pulmonary arterial hypertension
-
21256048 10.1016/j.healun.2010.11.009
-
Barst RJ, Oudiz RJ, Beardsworth A et al (2011) Pulmonary arterial hypertension and response to tadalafil (PHIRST) study group: tadalafil monotherapy and as add-on to background bosentan in patients with pulmonary arterial hypertension. J Heart Lung Transplant 30:632-643
-
(2011)
J Heart Lung Transplant
, vol.30
, pp. 632-643
-
-
Barst, R.J.1
Oudiz, R.J.2
Beardsworth, A.3
-
4
-
-
84856106514
-
A randomised double-blind placebo-controlled dose-ranging study of oral sildenfail citrate in treatment naive children with pulmonary arterial hypertension
-
22128226 10.1161/CIRCULATIONAHA.110.016667 1:CAS:528: DC%2BC38XotVGitg%3D%3D
-
Barst RJ, Dunbar I, Gaitan G et al (2012) A randomised double-blind placebo-controlled dose-ranging study of oral sildenfail citrate in treatment naive children with pulmonary arterial hypertension. Circulation 125:324-334
-
(2012)
Circulation
, vol.125
, pp. 324-334
-
-
Barst, R.J.1
Dunbar, I.2
Gaitan, G.3
-
5
-
-
84855386012
-
Childhood pulmonary arterial hypertension: Insights from the registry to evaluate early and long-term pulmonary arterial hypertension disease management
-
22086881 10.1161/CIRCULATIONAHA.111.026591
-
Barst RJ, McGoon MD, Elliott CG et al (2012) Childhood pulmonary arterial hypertension: insights from the registry to evaluate early and long-term pulmonary arterial hypertension disease management. Circulation 125:113-122
-
(2012)
Circulation
, vol.125
, pp. 113-122
-
-
Barst, R.J.1
McGoon, M.D.2
Elliott, C.G.3
-
6
-
-
30644470815
-
Neonatal persistent pulmonary hypertension treated with milrinone: Four case reports
-
16155380 10.1159/000088192
-
Bassler D, Choong K, McNamara P et al (2006) Neonatal persistent pulmonary hypertension treated with milrinone: four case reports. Biol Neonate 89:1-5
-
(2006)
Biol Neonate
, vol.89
, pp. 1-5
-
-
Bassler, D.1
Choong, K.2
McNamara, P.3
-
7
-
-
84857065088
-
Clinical features of paediatric pulmonary hypertension: A registry study
-
22240409 10.1016/S0140-6736(11)61621-8
-
Berger RM, Beghetti M, Humpl T et al (2012) Clinical features of paediatric pulmonary hypertension: a registry study. Lancet 379:537-546
-
(2012)
Lancet
, vol.379
, pp. 537-546
-
-
Berger, R.M.1
Beghetti, M.2
Humpl, T.3
-
8
-
-
0042261614
-
Sildenafil as a treatment for pulmonary hypertension
-
12937112 10.1136/adc.88.9.827 1:STN:280:DC%2BD3szpslKqsA%3D%3D
-
Carroll WD, Dhillon R (2003) Sildenafil as a treatment for pulmonary hypertension. Arch Dis Child 88:827-828
-
(2003)
Arch Dis Child
, vol.88
, pp. 827-828
-
-
Carroll, W.D.1
Dhillon, R.2
-
10
-
-
0142104985
-
Smad-dependent and Smad-independent pathways in TGF family signalling
-
14534577 10.1038/nature02006 1:CAS:528:DC%2BD3sXnvV2hs7c%3D
-
Derynck R, Zhang YE (2003) Smad-dependent and Smad-independent pathways in TGF family signalling. Nature 425:577-584
-
(2003)
Nature
, vol.425
, pp. 577-584
-
-
Derynck, R.1
Zhang, Y.E.2
-
11
-
-
77950627120
-
Characteristics and prospective 2-year follow-up of children with pulmonary arterial hypertension in France
-
20226425 10.1016/j.acvd.2009.12.001
-
Fraisse A, Jais X, Schleich JM et al (2010) Characteristics and prospective 2-year follow-up of children with pulmonary arterial hypertension in France. Arch Cardiovasc Dis 103:66-74
-
(2010)
Arch Cardiovasc Dis
, vol.103
, pp. 66-74
-
-
Fraisse, A.1
Jais, X.2
Schleich, J.M.3
-
12
-
-
67649523052
-
Tadalafil therapy for pulmonary arterial hypertension. Pulmonary arterial hypertension and response to tadalafil (PHIRST) study group
-
19470885 10.1161/CIRCULATIONAHA.108.839274 1:CAS:528:DC%2BD1MXms1alsb0%3D
-
Galie JN, Brundage BH, Ghofrani H et al (2009) Tadalafil therapy for pulmonary arterial hypertension. Pulmonary arterial hypertension and response to tadalafil (PHIRST) study group. Circulation 119:2894-2903
-
(2009)
Circulation
, vol.119
, pp. 2894-2903
-
-
Galie, J.N.1
Brundage, B.H.2
Ghofrani, H.3
-
13
-
-
79959752658
-
Management of pulmonary hypertension in down syndrome
-
21203772 10.1007/s00431-010-1378-1 1:CAS:528:DC%2BC3MXnslSit7o%3D
-
Hawkins A, Langton-Hewer S, Henderson J et al (2011) Management of pulmonary hypertension in down syndrome. Eur J Pediatr 170:915-921
-
(2011)
Eur J Pediatr
, vol.170
, pp. 915-921
-
-
Hawkins, A.1
Langton-Hewer, S.2
Henderson, J.3
-
14
-
-
21044449937
-
Beneficial effect of oral sildenafil therapy on childhood pulmonary arterial hypertension: Twelve-month clinical trial of a single drug, open-label, pilot study
-
15956137 10.1161/CIRCULATIONAHA.104.473371 1:CAS:528:DC%2BD2MXltVKmtrk%3D
-
Humpl T, Reyes JT, Holtby H et al (2005) Beneficial effect of oral sildenafil therapy on childhood pulmonary arterial hypertension: twelve-month clinical trial of a single drug, open-label, pilot study. Circulation 111:3274-3280
-
(2005)
Circulation
, vol.111
, pp. 3274-3280
-
-
Humpl, T.1
Reyes, J.T.2
Holtby, H.3
-
15
-
-
80051559475
-
Vardenafil in pulmonary arterial hypertension: A randomized, double-blind, placebo-controlled study. Efficacy and safety of vardenafil in the treatment of pulmonary arterial hypertension (evaluation) study group
-
21471085 10.1164/rccm.201101-0093OC 1:CAS:528:DC%2BC3MXpsF2nsLs%3D
-
Jing ZC, Yu ZX, Shen JY et al (2011) Vardenafil in pulmonary arterial hypertension: a randomized, double-blind, placebo-controlled study. Efficacy and safety of vardenafil in the treatment of pulmonary arterial hypertension (evaluation) study group. Am J Respir Crit Care Med 183:1723-1729
-
(2011)
Am J Respir Crit Care Med
, vol.183
, pp. 1723-1729
-
-
Jing, Z.C.1
Yu, Z.X.2
Shen, J.Y.3
-
16
-
-
84862327433
-
Acute effects of vardenafil on pulmonary artery responsiveness in pulmonary hypertension
-
doi: 10.1100/2012/718279
-
Karasu-Minareci E, Ozbudak I, Ozbillim G, et al (2012) Acute effects of vardenafil on pulmonary artery responsiveness in pulmonary hypertension. Sci World J 2012. doi: 10.1100/2012/718279
-
(2012)
Sci World J
, vol.2012
-
-
Karasu-Minareci, E.1
Ozbudak, I.2
Ozbillim, G.3
-
17
-
-
17044415276
-
Safety with pulmonary hypertension
-
15823634 10.1016/j.ijcard.2004.09.002
-
Karatza AA, Bush A, Magee AG (2005) Safety with pulmonary hypertension. Int J Cardiol 100:267-273
-
(2005)
Int J Cardiol
, vol.100
, pp. 267-273
-
-
Karatza, A.A.1
Bush, A.2
Magee, A.G.3
-
18
-
-
84855359486
-
10-year analysis of adverse event reports to the food and drug administration for phosphodiesterase type-5 inhibitors
-
22023666 10.1111/j.1743-6109.2011.02537.x
-
Lowe G, Costabile R (2012) 10-year analysis of adverse event reports to the food and drug administration for phosphodiesterase type-5 inhibitors. J Sex Med 9:265-270
-
(2012)
J Sex Med
, vol.9
, pp. 265-270
-
-
Lowe, G.1
Costabile, R.2
-
19
-
-
77956108380
-
Childhood idiopathic pulmonary arterial hypertension: A national cohort study
-
20406768 10.1136/hrt.2009.182378 1:STN:280:DC%2BC3cjnvFarug%3D%3D
-
Moledina S, Hislop AA, Foster H et al (2010) Childhood idiopathic pulmonary arterial hypertension: a national cohort study. Heart 96:1401-1406
-
(2010)
Heart
, vol.96
, pp. 1401-1406
-
-
Moledina, S.1
Hislop, A.A.2
Foster, H.3
-
20
-
-
33750602910
-
Sildenafil prevents rebound pulmonary hypertension after withdrawal of nitric oxide in children
-
16917115 10.1164/rccm.200605-694OC 1:CAS:528:DC%2BD28Xht1Oksr7I
-
Namachivayam P, Theilen U, Butt WW et al (2006) Sildenafil prevents rebound pulmonary hypertension after withdrawal of nitric oxide in children. Am J Respir Crit Care Med 174:1042-1047
-
(2006)
Am J Respir Crit Care Med
, vol.174
, pp. 1042-1047
-
-
Namachivayam, P.1
Theilen, U.2
Butt, W.W.3
-
21
-
-
67649579669
-
Updated clinical classification of pulmonary hypertension
-
10.1016/j.jacc.2009.04.012
-
Simmoneau G, Robbins IM, Beghetti M et al (2009) Updated clinical classification of pulmonary hypertension. J Am Coll Cardiol 54:S43-S54
-
(2009)
J Am Coll Cardiol
, vol.54
-
-
Simmoneau, G.1
Robbins, I.M.2
Beghetti, M.3
-
22
-
-
54549125950
-
Addition of sildenafil to long-term intravenous epoprostenol therapy in patients with pulmonary arterial hypertension: A randomized trial
-
18936500
-
Simonneau G, Rubin LJ, Galie N et al (2008) Addition of sildenafil to long-term intravenous epoprostenol therapy in patients with pulmonary arterial hypertension: a randomized trial. Ann Intern Med 149:521-530
-
(2008)
Ann Intern Med
, vol.149
, pp. 521-530
-
-
Simonneau, G.1
Rubin, L.J.2
Galie, N.3
-
23
-
-
43049124136
-
Sildenafil for pulmonary hypertension: Dose-dependent improvement in exercise performance
-
18249145 10.1016/j.pupt.2007.11.006 1:CAS:528:DC%2BD1cXlvVSgt7Y%3D
-
Spring RM, Ulrich S, Huber LC et al (2008) Sildenafil for pulmonary hypertension: dose-dependent improvement in exercise performance. Pulm Pharmacol Ther 21:516-521
-
(2008)
Pulm Pharmacol Ther
, vol.21
, pp. 516-521
-
-
Spring, R.M.1
Ulrich, S.2
Huber, L.C.3
-
24
-
-
77649106196
-
Inhibition of cGMP phosphodiesterase 5 suppresses matrix metalloproteinase-2 production in pulmonary artery smooth muscle cells
-
19793106 10.1111/j.1440-1681.2009.05304.x 1:CAS:528:DC%2BC3cXjslemsbc%3D
-
Sun X, Li Z, Liu Y et al (2010) Inhibition of cGMP phosphodiesterase 5 suppresses matrix metalloproteinase-2 production in pulmonary artery smooth muscle cells. Clin Exp Pharmacol Physiol 37:362-367
-
(2010)
Clin Exp Pharmacol Physiol
, vol.37
, pp. 362-367
-
-
Sun, X.1
Li, Z.2
Liu, Y.3
-
25
-
-
84863980719
-
Initial experience with tadalfil in pediatric pulmonary arterial hypertension
-
22402804 10.1007/s00246-012-0180-4
-
Takatsuki S, Calderbank M, Ivy DD (2012) Initial experience with tadalfil in pediatric pulmonary arterial hypertension. Pediatr Cardiol 33:683-688
-
(2012)
Pediatr Cardiol
, vol.33
, pp. 683-688
-
-
Takatsuki, S.1
Calderbank, M.2
Ivy, D.D.3
-
26
-
-
84879504791
-
Safety and efficacy of bosentan in combination with sildenafil in pulmonary arterial hypertension: The COMPASS-3 Study (abstract)
-
Torres F, Gupta H, Soto F, et al (2011) Safety and efficacy of bosentan in combination with sildenafil in pulmonary arterial hypertension: the COMPASS-3 Study (abstract). In: ERS Annual Congress 2011
-
(2011)
ERS Annual Congress
, vol.2011
-
-
Torres, F.1
Gupta, H.2
Soto, F.3
-
27
-
-
33750099295
-
Observations on peripheral microcirculation in young hypertensive patients
-
16739867
-
Tudor A, Muşat A, Bari M et al (2005) Observations on peripheral microcirculation in young hypertensive patients. Rom J Intern Med 43:73-78
-
(2005)
Rom J Intern Med
, vol.43
, pp. 73-78
-
-
Tudor, A.1
Muşat, A.2
Bari, M.3
-
29
-
-
84859779899
-
Ocular safety of sildenafil citrate when administered chronically for pulmonary arterial hypertension: Results from phase III, randomised, double-masked, placebo-controlled trial and open label extension
-
22354598 10.1136/bmj.e554
-
Wirostko B, Trssler C, Hwang L et al (2012) Ocular safety of sildenafil citrate when administered chronically for pulmonary arterial hypertension: results from phase III, randomised, double-masked, placebo-controlled trial and open label extension. BMJ 344:e554
-
(2012)
BMJ
, vol.344
, pp. 554
-
-
Wirostko, B.1
Trssler, C.2
Hwang, L.3
-
30
-
-
41849103027
-
Pharmacokinetic interaction between tadalafil and bosentan in healthy male subjects
-
18305126 10.1177/0091270008315315 1:CAS:528:DC%2BD1cXlvVGqsbg%3D
-
Wrishko RE, Dingemanse J, Yu A et al (2008) Pharmacokinetic interaction between tadalafil and bosentan in healthy male subjects. J Clin Pharmacol 48:610-618
-
(2008)
J Clin Pharmacol
, vol.48
, pp. 610-618
-
-
Wrishko, R.E.1
Dingemanse, J.2
Yu, A.3
|