Facility-level intervention to improve attendance and adherence among patients on anti-retroviral treatment in Kenya - A quasi-experimental study using time series analysis

BMC Health Services Research

Volumn 13, Issue 1, 2013, Pages

  Boruett, Patrick ^a   Kagai, Dorine ^b   Njogo, Susan ^b   Nguhiu, Peter ^a   Awuor, Christine ^b   Gitau, Lillian ^a   Chalker, John ^c   Ross Degnan, Dennis ^d   Wahlström, Rolf ^e   Tomson, Göran ^e  

^a Management Sciences for Health   (Kenya)

^b National AIDS and STI Control Programme   (Kenya)

^c MANAGEMENT SCIENCES FOR HEALTH   (United States)

^d HARVARD MEDICAL SCHOOL   (United States)

^e KAROLINSKA INSTITUTE   (Sweden)

Author keywords

Appointment keeping; Indicators; Medication gaps; Monitoring performance; Self reported adherence

Indexed keywords

ANTIRETROVIRUS AGENT;

ADULT; ARTICLE; CONFIDENCE INTERVAL; FEMALE; HEALTH PROMOTION; HOSPITAL MANAGEMENT; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; KENYA; LONGITUDINAL STUDY; MALE; MEDICATION COMPLIANCE; METHODOLOGY; PATIENT COMPLIANCE; SELF REPORT; STATISTICS;

ADULT; ANTI-RETROVIRAL AGENTS; APPOINTMENTS AND SCHEDULES; CONFIDENCE INTERVALS; FEMALE; HEALTH PROMOTION; HIV INFECTIONS; HUMANS; KENYA; LONGITUDINAL STUDIES; MALE; MEDICATION ADHERENCE; PATIENT COMPLIANCE; SELF REPORT;

EID: 84879491766     PISSN: None     EISSN: 14726963     Source Type: Journal    
DOI: 10.1186/1472-6963-13-242     Document Type: Article

References (26)

1. National AIDS Control Council, United Nations General Assembly Special Session on HIV and AIDS 2010: Country Report-Kenya Nairobi, Kenya: National AIDS Control Council 2010
2. UNAIDS, Global HIV/AIDS Response-Epidemic Update and Health Sector Progress towards Universal Access-Progress Report 2011 Geneva: World Health Organization 2011 23745633
3. Measuring adherence to antiretroviral treatment in resource-poor settings: the feasibility of collecting routine data for key indicators. Chalker J, Andualem T, Gitau L, Ntaganira J, Obua C, Tadeg H, Waako P, Ross-Degnan D, BMC Health Serv Res 2010 10 43 10.1186/1472-6963-10-43 20170479
4. WHO, Towards Universal Access, Scaling up Priority Interventions in the Health Sector; Progress Report Geneva: World Health Organization 2008
5. Non adherence to highly active antiretroviral therapy predicts progression to AIDS. Bangsberg DR, Perry S, Charlebois ED, Clark RA, Roberstson M, Andrew R, Moss A, AIDS 2001 15 1181 1183 10.1097/00002030-200106150-00015 11416722 (Pubitemid 32549871)
6. Use of electronic reminder devices to improve adherence to antiretroviral therapy: a systematic review. Wise J, Operario D, AIDS Patient Care STDS 2008 22 6 495 504 10.1089/apc.2007.0180 18462071
7. One year adherence to clinic visits after highly active antiretroviral therapy: a predictor of clinical progress in HIV patients. Park WB, Choe PG, Kim SH, Jo JH, Bang JH, Kim NJ, Oh M, Choe KW, J Intern Med 2007 261 268 275 10.1111/j.1365-2796.2006.01762.x 17305649
8. Voices on adherence to ART in Ethiopia and Uganda: A matter of choice or simply not an option? Gusdal AK, Obua C, Andualem T, Wahlström R, Tomson G, Peterson S, Ekström AM, Thorson A, Chalker J, Fochsen G, on behalf of the INRUD-IAA project, AIDS Care 2009 21 11 1381 1387 10.1080/09540120902883119 20024714
9. Measuring adherence to antiretroviral treatment in resource-poor settings: the clinical validity of key indicators. Ross-Degnan D, Pierre-Jacques M, Zhang F, Tadeg H, Gitau L, Ntaganira J, Balikuddembe R, Chalker J, Wagner A, BMC Health Serv Res 2010 10 42 10.1186/1472-6963-10-42 20170478
10. Pharmacy refill adherence compared with CD4 count changes for monitoring HIV-infected adults on antiretroviral therapy. Bisson GP, Gross R, Bellamy S, Chittams J, Hislop M, Regensberg L, Frank I, Maartens G, Nachega JB, Bisson GP, Gross R, Bellamy S, Chittams J, Hislop M, Regensberg L, Frank I, Maartens G, Nachega JB, PLoS Med 2008 5 5 109 10.1371/journal.pmed.0050109 18494555 (Pubitemid 351760907)
11. Adherence to protease inhibitor therapy and outcomes in patients with HIV infection. Patterson D, Swindells S, Mohr J, Ann Intern Med 2001 134 625 11281750
12. Adherence to antiretroviral therapy in sub-Saharan Africa and North America: a meta-analysis. Mills EJ, Nachega JB, Buchan I, Orbinski J, Attaran A, Singh S, Rachlis B, Wu P, Cooper C, Thabane L, Wilson K, Guyatt GH, Bangsberg DR, JAMA 2006 296 6 679 690 10.1001/jama.296.6.679 16896111 (Pubitemid 44200639)
13. Less than 95% adherence to nonnucleoside reverse transcriptase inhibitor therapy can lead to viral suppression. Bangsberg D, Clin Infect Dis 2006 43 939 941 10.1086/507526 16941380 (Pubitemid 44435526)
14. National AIDS/STI Control Programme, Annual Health Sector HIV Report 2009: Progress with the National Health Sector Response Nairobi: National AIDS and STI Control Program 2010
15. Improving Appointment Keeping and Adherence Monitoring In ART Facilities in Kenya: Views of Providers and Patients. Njogo SM, Presentation at the Third International Conference for Improving Use of Medicine, Antalya, Turkey, November 2011 http://www.inrud.org/ICIUM/ConferenceMaterials/544-njogo-c.pdf (accessed 29 May 2012)
16. Urgent need for coordination in adopting standardized antiretroviral adherence performance indicators. Chalker J, Wagner A, Tomson G, Laing R, Johnson K, Wahlstrom R, Ross-Degnan D, on behalf of INRUD-IAA, JAIDS 2010 53 2 159 161 10.1097/QAI.0b013e3181befa12 19861899
17. Monitoring adherence and defaulting for adherence therapy in five east African countries: an urgent need for standards. Chalker J, Andualem T, Minzi O, Ntaganira J, Ojoo A, Waako P, Ross-Degnan D, JIAPAC 2008 7 193 199 18626124
18. Organisational change theory and the use of indicators in general practice. Rhydderch M, Elwyn G, Marshall M, Grol R, Qual Saf Health Care 2004 13 213 217 10.1136/qshc.2003.006536 15175493 (Pubitemid 38797508)
19. Clinic attendance for medication refills and medication adherence amongst an antiretroviral treatment cohort in Uganda: a prospective study. Kunutsor S, Walley J, Katabira E, Muchuro S, Balidawa H, Namagala E, Ikoona E, AIDS Res Treat 2010 2010 872396 21490907
20. Outcomes of antiretroviral treatment program in Ethiopia: retention of patients in care is a major challenge and varies across health facilities. Assefa Y, Kiflie A, Tesfaye D, Haile Mariam D, Kloos H, Edwin W, Laga M, Van Damme W, BMC Health Serv Res 2011 11 81 10.1186/1472-6963-11-81 21501509
21. Cost-effectiveness of preventing loss to follow-up in HIV treatment programs: a Cote d'Ivoire appraisal. Messou E, Weinstein MC, Dabis F, Freedberg KA, PLoS Med 2009 6 10 1000173 10.1371/journal.pmed.1000173 19859538
22. Antiretroviral medication adherence and the development of class-specific antiretroviral resistance. Gardner EM, Burman WJ, Steiner JF, Anderson PL, Bangsberg DR, AIDS 2009 23 1035 1046 10.1097/QAD.0b013e32832ba8ec 19381075
23. Scaling-up antiretroviral treatment in Southern African countries with human resource shortage: how will health systems adapt? Van Damme W, Kober K, Kegels G, Soc Sci Med 2008 66 2108 2121 10.1016/j.socscimed.2008.01.043 18329774 (Pubitemid 351509687)
24. Understanding pathways for scaling up health services through the lens of complex adaptive systems. Paina L, Peters D, Health Policy Plan 2011 1 9 http://healpol.oxfordjournals.org/content/early/2011/08/05/heapol.czr054.full. pdf +html
25. Systems Thinking for Health Systems Strengthening Geneva: WHO, Savigny D De, Adam T, 2009
26. Segmented regression analysis of interrupted time series studies in medication use research. Wagner AK, Soumerai SB, Zhang F, Ross-Degnan D, J Clin Pharm Ther 2002 27 299 309 10.1046/j.1365-2710.2002.00430.x 12174032 (Pubitemid 34989269)