-
2
-
-
4544250814
-
Reactive oxygen species produced by NAD(P)H oxidase inhibit apoptosis in pancreatic cancer cells
-
Vaquero EC, Edderkaoui M, Pandol SJ, Gukovsky I, Gukovskaya AS. Reactive oxygen species produced by NAD(P)H oxidase inhibit apoptosis in pancreatic cancer cells. J Biol Chem 2004; 279: 34643- 34654.
-
(2004)
J Biol Chem
, vol.279
, pp. 34643-34654
-
-
Vaquero, E.C.1
Edderkaoui, M.2
Pandol, S.J.3
Gukovsky, I.4
Gukovskaya, A.S.5
-
3
-
-
0030980641
-
Mitogenic signaling mediated by oxidants in Ras-transformed fibroblasts
-
Irani K, Xia Y, Zweier JL, et al. Mitogenic signaling mediated by oxidants in Ras-transformed fibroblasts. Science 1997; 275: 1649- 1651.
-
(1997)
Science
, vol.275
, pp. 1649-1651
-
-
Irani, K.1
Xia, Y.2
Zweier, J.L.3
-
4
-
-
0035901606
-
Opposing functions of Ki- and Ha-Ras genes in the regulation of redox signals
-
Santillo M, Mondola P, Seru R, et al. Opposing functions of Ki- and Ha-Ras genes in the regulation of redox signals. Curr Biol 2001; 11: 614- 619.
-
(2001)
Curr Biol
, vol.11
, pp. 614-619
-
-
Santillo, M.1
Mondola, P.2
Seru, R.3
-
5
-
-
0032732639
-
Superoxide generated in v-Ha-ras-transduced human keratinocyte HaCaT cells
-
Yang JQ, Li SJ, Domann FE, Buettner GR, Oberley LW. Superoxide generated in v-Ha-ras-transduced human keratinocyte HaCaT cells. Mol Carcinog 1999; 26: 180- 188.
-
(1999)
Mol Carcinog
, vol.26
, pp. 180-188
-
-
Yang, J.Q.1
Li, S.J.2
Domann, F.E.3
Buettner, G.R.4
Oberley, L.W.5
-
6
-
-
0346363268
-
Suppression of the malignant phenotype in human pancreatic cancer cells by the overexpression of manganese superoxide dismutase
-
Wydert C, Roling B, Liu J, Ritchie JM, Oberley LW, Cullen JJ. Suppression of the malignant phenotype in human pancreatic cancer cells by the overexpression of manganese superoxide dismutase. Mol Cancer Ther 2003; 2: 361- 369.
-
(2003)
Mol Cancer Ther
, vol.2
, pp. 361-369
-
-
Wydert, C.1
Roling, B.2
Liu, J.3
Ritchie, J.M.4
Oberley, L.W.5
Cullen, J.J.6
-
7
-
-
37549046814
-
Modulation of reactive oxygen species (ROS) in pancreatic cancer: Insight into tumor growth suppression by the superoxide dismutases
-
Teoh MLT, Sun W, Smith BJ, Oberley LW, Cullen JJ. Modulation of reactive oxygen species (ROS) in pancreatic cancer: Insight into tumor growth suppression by the superoxide dismutases. Clin Cancer Res 2007; 13: 7441- 7450.
-
(2007)
Clin Cancer Res
, vol.13
, pp. 7441-7450
-
-
Teoh, M.L.T.1
Sun, W.2
Smith, B.J.3
Oberley, L.W.4
Cullen, J.J.5
-
8
-
-
20444464893
-
In vitro modeling of human pancreatic duct epithelial cell transformation defines gene expression changes induced by K-ras oncogenic activation in pancreatic carcinogenesis
-
Qian J, Niu J, Li M, Chiao PJ, Tsao MS. In vitro modeling of human pancreatic duct epithelial cell transformation defines gene expression changes induced by K-ras oncogenic activation in pancreatic carcinogenesis. Cancer Res 2005; 65: 5045- 5053.
-
(2005)
Cancer Res
, vol.65
, pp. 5045-5053
-
-
Qian, J.1
Niu, J.2
Li, M.3
Chiao, P.J.4
Tsao, M.S.5
-
9
-
-
23644443066
-
Targeting NAD(P)H:quinone oxidoreductase (NQO1) in pancreatic cancer
-
Lewis A, Ough M, Du J, Tsao MS, Oberley LW, Cullen JJ. Targeting NAD(P)H:quinone oxidoreductase (NQO1) in pancreatic cancer. Mol Carcinog 2005; 43: 215- 224.
-
(2005)
Mol Carcinog
, vol.43
, pp. 215-224
-
-
Lewis, A.1
Ough, M.2
Du, J.3
Tsao, M.S.4
Oberley, L.W.5
Cullen, J.J.6
-
10
-
-
34250262163
-
Preparation, preservation, recovery and use of irradiated feeder layers in cell culture research
-
Jessop NW, Hay RJ. Preparation, preservation, recovery and use of irradiated feeder layers in cell culture research. TCA Man. 1979; 5: 1137- 1139.
-
(1979)
TCA Man.
, vol.5
, pp. 1137-1139
-
-
Jessop, N.W.1
Hay, R.J.2
-
11
-
-
33846014691
-
Mitochondrial production of reactive oxygen species mediate dicumarol-induced cytotoxicity in cancer cells
-
Du J, Daniels DH, Asbury CA, et al. Mitochondrial production of reactive oxygen species mediate dicumarol-induced cytotoxicity in cancer cells. J Biol Chem 2006; 281: 37416- 37426.
-
(2006)
J Biol Chem
, vol.281
, pp. 37416-37426
-
-
Du, J.1
Daniels, D.H.2
Asbury, C.A.3
-
12
-
-
0037444154
-
The role of manganese superoxide dismutase in the growth of pancreatic adenocarcinoma
-
Cullen JJ, Weydert C, Hinkhouse MM, et al. The role of manganese superoxide dismutase in the growth of pancreatic adenocarcinoma. Cancer Res 2003; 63: 1297- 1303.
-
(2003)
Cancer Res
, vol.63
, pp. 1297-1303
-
-
Cullen, J.J.1
Weydert, C.2
Hinkhouse, M.M.3
-
13
-
-
48649095595
-
Extracellular redox state of human prostate cancer cells regulates biological and biochemical properties related to metastatic behavior
-
Chaiswing L, Zhong W, Cullen JJ, Oberley LW, Oberley TD. Extracellular redox state of human prostate cancer cells regulates biological and biochemical properties related to metastatic behavior. Cancer Res 2008; 68: 5820- 5826.
-
(2008)
Cancer Res
, vol.68
, pp. 5820-5826
-
-
Chaiswing, L.1
Zhong, W.2
Cullen, J.J.3
Oberley, L.W.4
Oberley, T.D.5
-
14
-
-
66249088726
-
Enhancing the antitumor activity of adriamycin and ionizing radiation
-
Sun W, Kalen AL, Smith BJ, Cullen JJ, Oberley LW. Enhancing the antitumor activity of adriamycin and ionizing radiation. Cancer Res 2009; 69: 4294- 4300.
-
(2009)
Cancer Res
, vol.69
, pp. 4294-4300
-
-
Sun, W.1
Kalen, A.L.2
Smith, B.J.3
Cullen, J.J.4
Oberley, L.W.5
-
15
-
-
70449723261
-
Genetic silencing of Nox2 and Nox4 reveals differential roles of these NADPH oxidase homologues in the vasopressor and dispogenic effects of brain angiotensin II
-
Peterson JR, Burmeister MA, Tian X, et al. Genetic silencing of Nox2 and Nox4 reveals differential roles of these NADPH oxidase homologues in the vasopressor and dispogenic effects of brain angiotensin II. Hypertension 2009; 54: 1106- 1114.
-
(2009)
Hypertension
, vol.54
, pp. 1106-1114
-
-
Peterson, J.R.1
Burmeister, M.A.2
Tian, X.3
-
16
-
-
0032504176
-
Nitroxides Tempol and tempo induce divergent signal transduction pathways in MDA-MB 231 breast cancer cells
-
Gusy S, Mitchell JB, Ehleiter D, Haimovitz-Friedman A, Kasid U. Nitroxides Tempol and tempo induce divergent signal transduction pathways in MDA-MB 231 breast cancer cells. J Biol Chem 1998; 273: 17871- 17878.
-
(1998)
J Biol Chem
, vol.273
, pp. 17871-17878
-
-
Gusy, S.1
Mitchell, J.B.2
Ehleiter, D.3
Haimovitz-Friedman, A.4
Kasid, U.5
-
17
-
-
0025322028
-
Biologically active, metal-independent superoxide dismutase mimics
-
Mitchell JB, Samuni A, Krishna MC, et al. Biologically active, metal-independent superoxide dismutase mimics. Biochemistry 1990; 29: 2802- 2807.
-
(1990)
Biochemistry
, vol.29
, pp. 2802-2807
-
-
Mitchell, J.B.1
Samuni, A.2
Krishna, M.C.3
-
18
-
-
0025079927
-
SOD-like activity of 5-membered nitroxide spin labels
-
Samuni A, Min A, Krishna CM, Mitchell JB, Russo A. SOD-like activity of 5-membered nitroxide spin labels. Adv Exp Med Biol 1990; 264: 85- 92.
-
(1990)
Adv Exp Med Biol
, vol.264
, pp. 85-92
-
-
Samuni, A.1
Min, A.2
Krishna, C.M.3
Mitchell, J.B.4
Russo, A.5
-
19
-
-
0026050304
-
Mn(III)-desferrioxamine superoxide dismutase mimic: Alternative modes of action
-
Mitchell JB, Degraff W, Kaufman D, et al. Mn(III)-desferrioxamine superoxide dismutase mimic: Alternative modes of action. Arch Biochem Biophys 1991; 289: 62- 70.
-
(1991)
Arch Biochem Biophys
, vol.289
, pp. 62-70
-
-
Mitchell, J.B.1
Degraff, W.2
Kaufman, D.3
-
20
-
-
0034660880
-
The role of cellular glutathione peroxidase redox regulation in the suppression of tumor cell growth by manganese superoxide dismutase
-
Li S, Yan T, Yang JQ, Oberley TD, Oberley LW. The role of cellular glutathione peroxidase redox regulation in the suppression of tumor cell growth by manganese superoxide dismutase. Cancer Res 2000; 60: 3927- 3939.
-
(2000)
Cancer Res
, vol.60
, pp. 3927-3939
-
-
Li, S.1
Yan, T.2
Yang, J.Q.3
Oberley, T.D.4
Oberley, L.W.5
-
21
-
-
1642288979
-
Redox regulation of pancreatic cancer cell growth: Role of glutathione peroxidase in the suppression of the malignant phenotype
-
Liu J, Hinkhouse MM, Sun W, et al. Redox regulation of pancreatic cancer cell growth: Role of glutathione peroxidase in the suppression of the malignant phenotype. Hum Gene Ther 2004; 15: 239- 250.
-
(2004)
Hum Gene Ther
, vol.15
, pp. 239-250
-
-
Liu, J.1
Hinkhouse, M.M.2
Sun, W.3
-
22
-
-
1142275321
-
Detection of K-ras mutations in the plasma DNA of pancreatic cancer patients
-
Uemura T, Hibi K, Kaneko T, et al. Detection of K-ras mutations in the plasma DNA of pancreatic cancer patients. J Gastroenterol 2004; 39: 56- 60.
-
(2004)
J Gastroenterol
, vol.39
, pp. 56-60
-
-
Uemura, T.1
Hibi, K.2
Kaneko, T.3
-
23
-
-
0036048967
-
Chronic pancreatitis and pancreatic cancer
-
Maisonneuve P, Lowenfels AB. Chronic pancreatitis and pancreatic cancer. Dig Dis 2002; 20: 32- 37.
-
(2002)
Dig Dis
, vol.20
, pp. 32-37
-
-
Maisonneuve, P.1
Lowenfels, A.B.2
-
24
-
-
33646577163
-
Genetic and biology of pancreatic ductal adenocarcinoma
-
Hezel AF, Kimmelman AC, Stanger BZ, Bardeesy N, Dephino RA. Genetic and biology of pancreatic ductal adenocarcinoma. Genes Dev 2006; 20: 1218- 1249.
-
(2006)
Genes Dev
, vol.20
, pp. 1218-1249
-
-
Hezel, A.F.1
Kimmelman, A.C.2
Stanger, B.Z.3
Bardeesy, N.4
Dephino, R.A.5
-
25
-
-
0028175091
-
Raf meets Ras: Completing the framework of a signal transduction pathway
-
Avruch J, Zhang XF, Kyriakis JM. Raf meets Ras: Completing the framework of a signal transduction pathway. Trends Biochem Sci 1994; 19: 279- 283.
-
(1994)
Trends Biochem Sci
, vol.19
, pp. 279-283
-
-
Avruch, J.1
Zhang, X.F.2
Kyriakis, J.M.3
-
26
-
-
0028825531
-
Ras target proteins in eukaryotic cells
-
Marshall MS. Ras target proteins in eukaryotic cells. FASEB J 1995; 9: 1311- 1318.
-
(1995)
FASEB J
, vol.9
, pp. 1311-1318
-
-
Marshall, M.S.1
-
27
-
-
34548543291
-
DNA damage, superoxide and mutant K-ras in lung adenocarcinoma cells
-
Romanowska M, Macaig A, Smith AL, et al. DNA damage, superoxide and mutant K-ras in lung adenocarcinoma cells. Free Radic Biol Med 2007; 43: 1145- 1155.
-
(2007)
Free Radic Biol Med
, vol.43
, pp. 1145-1155
-
-
Romanowska, M.1
Macaig, A.2
Smith, A.L.3
-
28
-
-
57749113487
-
Altered detoxification status and increased resistance to oxidative stress by K-ras transformation
-
Recktenwald CV, Kellner R, Lichtenfels R, Seliger B. Altered detoxification status and increased resistance to oxidative stress by K-ras transformation. Cancer Res 2008; 68: 10068- 10093.
-
(2008)
Cancer Res
, vol.68
, pp. 10068-10093
-
-
Recktenwald, C.V.1
Kellner, R.2
Lichtenfels, R.3
Seliger, B.4
-
29
-
-
24944573845
-
Pancreatic cancer cell radiation survival and prenyltransferase inhibition: The role of K-ras
-
Brunner TB, Cengel KA, Hahn SM, et al. Pancreatic cancer cell radiation survival and prenyltransferase inhibition: The role of K-ras. Cancer Res 2005; 65: 8433- 8441.
-
(2005)
Cancer Res
, vol.65
, pp. 8433-8441
-
-
Brunner, T.B.1
Cengel, K.A.2
Hahn, S.M.3
-
30
-
-
2442693092
-
The superoxide-generating oxidase Nox1 is functionally required for Ras oncogene transformation
-
Mitushita J, Lambeth JD, Kanata T. The superoxide-generating oxidase Nox1 is functionally required for Ras oncogene transformation. Cancer Res 2004; 64: 3580- 3585.
-
(2004)
Cancer Res
, vol.64
, pp. 3580-3585
-
-
Mitushita, J.1
Lambeth, J.D.2
Kanata, T.3
-
31
-
-
34250888056
-
Regulation of Nox and Duox enzymatic activity and expression
-
Lambeth JD, Kawahara T, Diebold B. Regulation of Nox and Duox enzymatic activity and expression. Free Radic Biol Med 2007; 43: 319- 331.
-
(2007)
Free Radic Biol Med
, vol.43
, pp. 319-331
-
-
Lambeth, J.D.1
Kawahara, T.2
Diebold, B.3
-
32
-
-
0035504739
-
Gene expression profiles of pancreatic cancer and stromal desmoplasia
-
Crnogorac-Jurcevic T, Efthimiou E, Capelli P, et al. Gene expression profiles of pancreatic cancer and stromal desmoplasia. Oncogene 2001; 20: 7437- 7446.
-
(2001)
Oncogene
, vol.20
, pp. 7437-7446
-
-
Crnogorac-Jurcevic, T.1
Efthimiou, E.2
Capelli, P.3
-
33
-
-
78751614988
-
Role of Rac-1 dependent NADPH oxidase in the growth of pancreatic cancer
-
Du J, Liu J, Smith BJ, Tsao MS, Cullen JJ. Role of Rac-1 dependent NADPH oxidase in the growth of pancreatic cancer. Cancer Gene Ther 2011; 18: 135- 143.
-
(2011)
Cancer Gene Ther
, vol.18
, pp. 135-143
-
-
Du, J.1
Liu, J.2
Smith, B.J.3
Tsao, M.S.4
Cullen, J.J.5
-
34
-
-
59849084800
-
Increased levels of superoxide and H2O2 mediate the differential susceptibility of cancer cells versus normal cells to glucose deprivation
-
Aykin-Burns N, Ahmad IM, Zhu Y, Oberley LW, Spitz DR. Increased levels of superoxide and H2O2 mediate the differential susceptibility of cancer cells versus normal cells to glucose deprivation. Biochem J 2009; 418: 29- 37.
-
(2009)
Biochem J
, vol.418
, pp. 29-37
-
-
Aykin-Burns, N.1
Ahmad, I.M.2
Zhu, Y.3
Oberley, L.W.4
Spitz, D.R.5
|