Circulating and dietary magnesium and risk of cardiovascular disease: A systematic review and meta-analysis of prospective studies

American Journal of Clinical Nutrition

Volumn 98, Issue 1, 2013, Pages 160-173

  Del Gobbo, Liana C ^a   Imamura, Fumiaki ^b   Wu, Jason H Y ^b   De Oliveira Otto, Marcia C ^b   Chiuve, Stephanie E ^c   Mozaffarian, Dariush ^d,e  

^a Department of Nutrition ^*  (United States)

^b HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^c Division of Preventive Medicine   (United States)

^d Division of Cardiovascular Medicine   (United States)

^e BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MAGNESIUM;

ARTICLE; CARDIOVASCULAR DISEASE; CARDIOVASCULAR RISK; DIETARY INTAKE; FATALITY; HUMAN; INCIDENCE; MAGNESIUM BLOOD LEVEL; SYSTEMATIC REVIEW;

CARDIOVASCULAR DISEASES; DATABASES, FACTUAL; DIET; DIETARY SUPPLEMENTS; HUMANS; MAGNESIUM; RANDOMIZED CONTROLLED TRIALS AS TOPIC; RISK FACTORS;

EID: 84879454311     PISSN: 00029165     EISSN: 19383207     Source Type: Journal    
DOI: 10.3945/ajcn.112.053132     Document Type: Article

References (45)

1. Shechter M. Magnesium and cardiovascular system. Magnes Res 2010; 23:60-72.
2. Mubagwa K, Gwanyanya A, Zakharov S, Macianskiene R. Regulation of cation channels in cardiac and smooth muscle cells by intracellular magnesium. Arch Biochem Biophys 2007;458:73-89.
3. AHA (ECC Guidelines). Guidelines for cardiopulmonary resuscitation and emergency cardiovascular care, Part 8: Advanced challenges in resuscitation: Section 1: Life-threatening electrolyte abnormalities. Circulation 2000;102:I217-22.
4. Klevay LM, Milne DB. Low dietary magnesium increases supraventricular ectopy. Am J Clin Nutr 2002;75:550-4.
5. Nielsen FH, Milne DB, Klevay LM, Gallagher S, Johnson L. Dietary magnesium deficiency induces heart rhythm changes, impairs glucose tolerance, and decreases serum cholesterol in postmenopausal women. J Am Coll Nutr 2007;26:121-32.
6. Nielsen FH, Milne DB, Gallagher S, Johnson L, Hoverson B. Moderate magnesium deprivation results in calcium retention and altered potassium and phosphorus excretion by postmenopausal women. Magnes Res 2007;20:19-31.
7. Song Y, Manson JE, Cook NR, Albert CM, Buring JE, Liu S. Dietary magnesium intake and risk of cardiovascular disease among women. Am J Cardiol 2005;96:1135-41.
8. Arnaud MJ. Update on the assessment of magnesium status. Br J Nutr 2008;99:S24-36.
9. Stroup DF, Berlin JA, Morton SC, Olkin I, Williamson GD, Rennie D, Moher D, Becker BJ, Sipe TA, Thacker SB. Meta-analysis of observational studies in epidemiology: a proposal for reporting. JAMA 2000; 283:2008-12.
10. Larsson SC, Orsini N, Wolk A. Dietary magnesium intake and risk of stroke: a meta-analysis of prospective studies. Am J Clin Nutr 2012;95: 362-6.
11. Zhang W. Point of care testing of ionized magnesium in blood with potentiometric sensors-opportunities and challenges. Am J Biomed Sci 2011;3:301-12.
12. Liao F, Folsom AR, Brancati FL. Is low magnesium concentration a risk factor for coronary heart disease? The Atherosclerosis Risk in Communities (ARIC) Study. Am Heart J 1998;136:480-90.
13. Peacock JM, Ohira T, Post W, Sotoodehnia N, Rosamond W, Folsom AR. Serum magnesium and risk of sudden cardiac death in the Atherosclerosis Risk in Communities (ARIC) Study. Am Heart J 2010;160: 464-70.
14. Abbott RD, Ando F, Masaki KH, Tung KH, Rodriguez BL, Petrovitch H, Yano K, Curb JD. Dietary magnesium intake and the future risk of coronary heart disease (the Honolulu Heart Program). Am J Cardiol 2003;92:665-9.
15. Al-Delaimy WK, Rimm EB, Willett WC, Stampfer MJ, Hu FB. Magnesium intake and risk of coronary heart disease among men. J Am Coll Nutr 2004;23:63-70.
16. Chiuve SE, Korngold EC, Januzzi JL Jr, Gantzer ML, Albert CM. Plasma and dietary magnesium and risk of sudden cardiac death in women. Am J Clin Nutr 2011;93:253-60.
17. Elwood PC, Fehily AM, Ising H, Poor DJ, Pickering J, Kamel F. Dietary magnesium does not predict ischaemic heart disease in the Caerphilly cohort. Eur J Clin Nutr 1996;50:694-7.
18. Ford ES. Serum magnesium and ischaemic heart disease: findings from a national sample of US adults. Int J Epidemiol 1999;28:645-51.
19. Kaluza J, Orsini N, Levitan EB, Brzozowska A, Roszkowski W, Wolk A. Dietary calcium and magnesium intake and mortality: a prospective study of men. Am J Epidemiol 2010;171:801-7.
20. Khan AM, Sullivan L, McCabe E, Levy D, Vasan RS, Wang TJ. Lack of association between serum magnesium and the risks of hypertension and cardiovascular disease. Am Heart J 2010;160:715-20.
21. Leone N, Courbon D, Ducimetiere P, Zureik M. Zinc, copper, and magnesium and risks for all-cause, cancer, and cardiovascular mortality. Epidemiol 2006;17:308-14.
22. Marniemi J, Järvisalob J, Toikkaa T, Räihä I, Ahotupa M, Sourander L. Blood vitamins, mineral elements and inflammation markers as risk factors of vascular and non-vascular disease mortality in an elderly population. Int J Epidemiol 1998;27:799-807.
23. de Oliveira Otto MC, Alonso A, Lee DH, Delclos GL, Bertoni AG, Jiang R, Lima JA, Symanski E, Jacobs DR Jr, Nettleton JA. Dietary intakes of zinc and heme iron from red meat, but not from other sources, are associated with greater risk of metabolic syndrome and cardiovascular disease. J Nutr 2012;142:526-33.
24. Reffelmann T, Ittermann T, Dörr M, Völzke H, Reinthaler M, Petersmann A, Felix SB. Low serum magnesium concentrations predict cardiovascular and all-cause mortality. Atherosclerosis 2011;219:280-4.
25. Reunanen A, Knekt P, Marniemi J, Mäki J, Maatela J, Aromaa A. Serum calcium, magnesium, copper and zinc and risk of cardiovascular death. Eur J Clin Nutr 1996;50:431-7.
26. Zhang W, Iso H, Ohira T, Date C, Tamakoshi A; JACC Study Group. Associations of dietary magnesium intake with mortality from cardiovascular disease: the JACC study. Atherosclerosis 2012;221: 587-95.
27. Hayden JA, Côté P, Bombardier C. Evaluation of the quality of prognosis studies in systematic reviews. Ann Intern Med 2006;144:427-37.
28. Orsini N, Bellocco R, Greenland S. Generalized least squares for trend estimation of summarized dose-response data. Stata J 2006;6: 40-57.
29. Symons MJ, Moore DT. Hazard rate ratio and prospective epidemiological studies. J Clin Epidemiol 2002;55:893-9.
30. Higgins JP, Thompson S. Quantifying heterogeneity in a meta-analysis. Stat Med 2002;21:1539-58.
31. Egger M, Smith GD, Schneider M, Minder C. Bias in meta-analysis detected by a simple, graphical test. BMJ 1997;315:629-634.
32. Begg CB, Mazumdar M. Operating characteristics of a rank correlation test for publication bias. Biometrics 1994;50:1088-101.
33. Duval S, Tweedie R. Trim and fill: a simple funnel plot based method of testing and adjusting for publication bias in meta-analysis. Biometrics 2000;56:455-63.
34. Lowenstein FW, Stanton MF. Serum magnesium levels in the United States, 1971-1974. J Am Coll Nutr 1986;5:399-414.
35. Tietz NW. Clinical guide to laboratory tests. Philadelphia, PA: WB Saunders, 1990.
36. Institute of Medicine (IOM). Dietary Reference Intakes for calcium, phosphorus, magnesium, vitamin D, and fluoride. Washington, DC: National Academies Press, 1997.
37. Song Y, He K, Levitan EB, Manson JE, Liu S. Effects of oral magnesium supplementation on glycaemic control in Type 2 diabetes: a meta-analysis of randomized double-blind controlled trials. Diabet Med 2006;23:1050-6.
38. Ohira T, Peacock JM, Iso H, Chambless LE, Rosamond WD, Folsom AR. Serum and dietary magnesium and risk of ischemic stroke: the Atherosclerosis Risk in Communities Study. Am J Epidemiol 2009; 169:1437-44.
39. Amighi J, Sabeti S, Schlager O, Mlekusch W, Exner M, Lalouschek W, Ahmadi R, Minar E, Schillinger M. Low serum magnesium predicts neurological events in patients with advanced atherosclerosis. Stroke 2004;35:22-7.
40. Meyer TE, Verwoert GC, Hwang S-J, Glazer NL, Smith AV, van Rooij FJ, Ehret GB, Boerwinkle E, Felix JF, Leak TS, et al. Genome-wide association studies of serum magnesium, potassium, and sodium concentrations identify six loci influencing serum magnesium levels. PLoS Genet 2010;6:e1001045.
41. Saris NE, Mervaala E, Karppanen H, Khawaja JA, Lewenstam A. Magnesium: an update on physiological, clinical and analytical aspects. Clin Chim Acta 2000;294:1-26.
42. Song Y, Sesso HD, Manson JE, Cook NR, Buring JE, Liu S. Dietary magnesium intake and risk of incident hypertension among middleaged and older US women in a 10-year follow-up study. Am J Cardiol 2006;98:1616-21.
43. Moshfegh A, Golman J, Auhja J, Rhodes D, Lacomb R. What we eat in America, NHANES 2005-2006: usual intakes from food and water compared to 1997 Dietary Reference Intakes for vitamin D, calcium, phosphorus and magnesium. Washington, DC: US Department of Agriculture, Agricultural Research Service, 2009.
44. Mozaffarian D, Capewell S. United Nations' dietary policies to prevent cardiovascular disease. BMJ 2011;343:d5747.
45. Hess MW, Hoenderop JG, Bindels RJM, Drenth JPH. Systematic review: hypomagnesaemia induced by proton pump inhibition. Aliment Pharmacol Ther 2012;36:405-13.