Safety evaluation of Whole Algalin Protein (WAP) from Chlorella protothecoides

Food and Chemical Toxicology

Volumn 59, Issue , 2013, Pages 34-45

  Szabo, Nancy J ^a   Matulka, Ray A ^a   Chan, Teresa ^b  

^a Burdock Group   (United States)

^b Solazyme Roquette Nutritionals   (United States)

Author keywords

Chlorella protothecoides; Clastogenic; Genotoxic; Mutagenic; Subchronic; Toxicity

Indexed keywords

PROTEIN; UNCLASSIFIED DRUG; WHOLE ALGALIN PROTEIN;

ANIMAL EXPERIMENT; ANIMAL FOOD; ARTICLE; BACTERIAL STRAIN; BODY WEIGHT; CHLORELLA; CHLORELLA PROTOTHECOIDES; CLINICAL CHEMISTRY; CONTROLLED STUDY; ESCHERICHIA COLI; FEMALE; FOOD ALLERGY; FOOD INTAKE; HEMATOLOGY; HISTOPATHOLOGY; HUMAN REPEAT INSULT PATCH TEST; IN VITRO STUDY; IN VIVO STUDY; MALE; MICROALGA; MORTALITY; NONHUMAN; OPHTHALMOLOGY; ORGAN WEIGHT; PATCH TEST; PROTEIN ANALYSIS; RAT; SALMONELLA TYPHIMURIUM; URINALYSIS;

Β-METHYLAMINO-L-ALANINE; 2-AA; 2-AMINOANTHRACENE; 4-NITRO-O-PHENYLENE-DIAMINE; 4-NOPD; AAALAC; ANALYSIS OF VARIANCE; ANOVA; AOAC; APT; ASSOCIATION OF ANALYTICAL COMMUNITIES; ATOPY PATCH TEST; BMAA; CHLORELLA PROTOTHECOIDES; CLASTOGENIC; CPA; CYCLOPHOSPHAMIDE; DBPCFC; DIET INDUCED OBESITY; DIO; DOUBLE-BLIND PLACEBO-CONTROLLED FOOD CHALLENGE; GCP; GENERALLY RECOGNIZED AS SAFE; GENOTOXIC; GLP; GOOD CLINICAL PRACTICE; GOOD LABORATORY PRACTICE; GRAS; GRAS NOTIFICATION; GRN; HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY/FLUORESCENCE DETECTION; HPLC/FL; HRIPT; HUMAN REPEAT-INSULT PATCH TEST; I.P.; ICH; IGE; IMMUNOGLOBULIN E; INTERNATIONAL ASSOCIATION FOR ASSESSMENT AND ACCREDITATION OF LABORATORY ANIMAL CARE INTERNATIONAL; INTERNATIONAL CONFERENCE ON HARMONISATION; INTRAPERITONEAL; MAXIMUM TOLERATED DOSE; METHYLMETHANESULFONATE; MMS; MTD; MUTAGENIC; NAN(3); NO-OBSERVED-ADVERSE-EFFECT LEVEL; NOAEL; OECD; ORGANISATION FOR ECONOMIC CO-OPERATION AND DEVELOPMENT; PHEIDEA; PHEOPHORBIDE A; SKIN PRICK TEST; SODIUM AZIDE; SPT; SUBCHRONIC; TFA; TOTAL FATTY ACID; TOXICITY; UNITED STATES FOOD AND DRUG ADMINISTRATION; US FDA; WAP; WHOLE ALGALIN PROTEIN;

ADULT; ALGAL PROTEINS; ANIMALS; CHLORELLA; DIETARY PROTEINS; ESCHERICHIA COLI; FEMALE; FOOD HYPERSENSITIVITY; HUMANS; MALE; MICE, INBRED STRAINS; MIDDLE AGED; MUTAGENICITY TESTS; NO-OBSERVED-ADVERSE-EFFECT LEVEL; PATCH TESTS; PLANT PROTEINS; RANDOM ALLOCATION; RATS; RATS, SPRAGUE-DAWLEY; RATS, WISTAR; RISK; SALMONELLA TYPHIMURIUM; TOXICITY TESTS, SUBCHRONIC;

AUXENOCHLORELLA PROTOTHECOIDES; ESCHERICHIA COLI; MUS; RATTUS; RODENTIA; SALMONELLA TYPHIMURIUM;

EID: 84879449977     PISSN: 02786915     EISSN: 18736351     Source Type: Journal    
DOI: 10.1016/j.fct.2013.05.035     Document Type: Article

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