Acute inhalation toxicity of ammonia: Revisiting the importance of RD50 and LCT01/50 relationships for setting emergency response guideline values

Regulatory Toxicology and Pharmacology

Volumn 66, Issue 3, 2013, Pages 315-325

  Pauluhn, Jürgen ^a  

^a BAYER PHARMA AG   (Germany)

Author keywords

Acute inhalation; Acute toxic lethal potency; Emergency response guidelines; Haber's rule; Inhalation dosimetry; Respiratory reflexes; Sensory irritation; Time adjustments; Toxic load exponent

Indexed keywords

AMMONIA;

ACUTE TOXICITY; ANALYTICAL PARAMETERS; ANIMAL EXPERIMENT; ARTICLE; BIOASSAY; BREATHING REFLEX; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DOSIMETRY; EMERGENCY RESPONSE GUIDELINE VALUE; ENVIRONMENTAL EXPOSURE; FEMALE; INHALATION; LC 50; LCT 01; LUNG VENTILATION; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; REFERENCE VALUE; SPECIES DIFFERENCE; TOXICITY TESTING;

AIR POLLUTANTS; AMMONIA; ANIMALS; DATA INTERPRETATION, STATISTICAL; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; GUIDELINES AS TOPIC; INHALATION EXPOSURE; LETHAL DOSE 50; MALE; RATS; RATS, WISTAR; SURVIVAL ANALYSIS; THRESHOLD LIMIT VALUES; TOXICITY TESTS, ACUTE;

RATTUS; RATTUS NORVEGICUS;

EID: 84879434498     PISSN: 02732300     EISSN: 10960295     Source Type: Journal    
DOI: 10.1016/j.yrtph.2013.05.008     Document Type: Article

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