Role of the cmcH-ccaR intergenic region and ccaR overexpression in cephamycin C biosynthesis in Streptomyces clavuligerus

Applied Microbiology and Biotechnology

Volumn 97, Issue 13, 2013, Pages 5869-5880

  Kurt, Aslihan ^a,b   Álvarez Álvarez, Rubén ^c   Liras, Paloma ^c   Özcengiz, Gülay ^a  

^a MIDDLE EAST TECHNICAL UNIVERSITY   (Turkey)

^b YUZUNCU YIL UNIVERSITY   (Turkey)

^c UNIVERSITY OF LEÓN   (Spain)

Author keywords

ccaR; Cephamycin C; Cephamycin C overproducer strains; Streptomyces clavuligerus

Indexed keywords

CCAR; CEPHAMYCIN C; EXPRESSION ANALYSIS; INTERGENIC REGIONS; MESSENGER RNAS (MRNA); REVERSE TRANSCRIPTION PCR; STREPTOMYCES CLAVULIGERUS; TRANSCRIPTION TERMINATORS;

BACTERIA; BIOCHEMISTRY; BIOSYNTHESIS; GENES; POLYMERASE CHAIN REACTION; RNA;

TRANSCRIPTION;

CEPHAMYCIN C; CLAVULANIC ACID; MESSENGER RNA;

BACTERIUM; CHROMOSOME; GENE EXPRESSION; POLYMERASE CHAIN REACTION;

ARTICLE; BACTERIAL GENE; BACTERIAL STRAIN; BLA GENE; BLP GENE; CCAR GENE; CEFD GENE; CEFE GENE; CMCH GENE; CMCI GENE; CMCJ GENE; DRUG SYNTHESIS; GENE EXPRESSION; GENE OVEREXPRESSION; LAT GENE; NONHUMAN; ORF10 GENE; PBPA GENE; PCBAB GENE; PCBC GENE; PCBR GENE; STREPTOMYCES CLAVULIGERUS;

BIOSYNTHETIC PATHWAYS; CEPHAMYCINS; CLAVULANIC ACID; DNA, INTERGENIC; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, BACTERIAL; GENES, BACTERIAL; REAL-TIME POLYMERASE CHAIN REACTION; SEQUENCE DELETION; STREPTOMYCES; TRANSCRIPTION FACTORS;

STREPTOMYCES CLAVULIGERUS;

EID: 84879422084     PISSN: 01757598     EISSN: 14320614     Source Type: Journal    
DOI: 10.1007/s00253-013-4721-4     Document Type: Article

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