Recombinant L-phenylalanine ammonia lyase from Rhodosporidium toruloides as a potential anticancer agent

Biotechnology and Applied Biochemistry

Volumn 60, Issue 3, 2013, Pages 316-322

  Babich, Olga O ^a   Pokrovsky, Vadim S ^b   Anisimova, Natalia Yu ^c   Sokolov, Nikolai N ^b   Prosekov, Alexander Yu ^a  

^a KEMEROVO STATE UNIVERSITY   (Russian Federation)

^b INSTITUTE OF BIOMEDICAL CHEMISTRY   (Russian Federation)

^c N N BLOKHIN RUSSIAN CANCER RESEARCH CENTER   (Russian Federation)

Author keywords

anticancer activity, cytotoxic enzyme, recombinant enzyme; l phenylalanine ammonia lyase; Rhodosporidium toruloides

Indexed keywords

CYTOTOXIC; CYTOTOXICITY IN VITRO; L-PHENYLALANINE AMMONIA LYASE; PHENYLALANINE AMMONIA-LYASE; POTENTIAL ANTICANCER AGENTS; PURIFICATION PROCEDURES; RHODOSPORIDIUM TORULOIDES; TEMPERATURE OPTIMUMS;

AMMONIA; CELL CULTURE; CYTOTOXICITY; ENZYME ACTIVITY; ESCHERICHIA COLI; PURIFICATION;

AMINO ACIDS;

ANTINEOPLASTIC AGENT; PHENYLALANINE AMMONIA LYASE; RECOMBINANT PHENYLALANINE AMMONIA LYASE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL STRAIN; CANCER CELL CULTURE; CANCER SURVIVAL; CONTROLLED STUDY; CYTOTOXICITY; DRUG TOLERANCE; ENZYME PURIFICATION; ESCHERICHIA COLI; FEMALE; HUMAN; HUMAN CELL; IN VITRO STUDY; LIFESPAN; LYMPHOMA; MOUSE; NONHUMAN; PH; PROTEIN EXPRESSION; RHODOSPORIDIUM TORULOIDES; TEMPERATURE;

ANIMALS; ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; FEMALE; HUMANS; HYDROGEN-ION CONCENTRATION; MCF-7 CELLS; MICE; PHENYLALANINE AMMONIA-LYASE; RECOMBINANT PROTEINS; TEMPERATURE; YEASTS;

MUS; RHODOSPORIDIUM TORULOIDES;

EID: 84879416559     PISSN: 08854513     EISSN: 14708744     Source Type: Journal    
DOI: 10.1002/bab.1089     Document Type: Article

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