Vasorelaxant action of an ethylacetate fraction of Euphorbia humifusa involves NO-cGMP pathway and potassium channels

Journal of Ethnopharmacology

Volumn 148, Issue 2, 2013, Pages 655-663

  Wang, Ting Ting ^a   Zhou, Guang Hai ^a   Kho, Joung Hyun ^b   Sun, Yuan Yuan ^a   Wen, Jin Fu ^a   Kang, Dae Gill ^b   Lee, Ho Sub ^b   Cho, Kyung Woo ^a   Jin, Song Nan ^a  

^a TAISHAN MEDICAL UNIVERSITY   (China)

^b Wonkwang University   (South Korea)

Author keywords

Akt; eNOS; Euphorbia humifusa; Guanosine 3 ,5 cyclic monophosphate; Nitric oxide; Potassium channels

Indexed keywords

1H 1,2,4 OXADIAZOLO[4,3 A]QUINOXALIN 1 ONE; 2 AMINOETHOXYDIPHENYLBORANE; ACETIC ACID ETHYL ESTER; APAMIN; ATROPINE; CHARYBDOTOXIN; CYCLIC GMP; ENDOTHELIAL NITRIC OXIDE SYNTHASE; EUPHORBIA EXTRACT; EUPHORBIA HUMIFUSA EXTRACT; GADOLINIUM; GLIBENCLAMIDE; IBERIOTOXIN; INDOMETACIN; INTERMEDIATE CONDUCTANCE CALCIUM ACTIVATED POTASSIUM CHANNEL; METHANOL; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; PHENYLEPHRINE; PROPRANOLOL; PROTEIN KINASE B; TETRYLAMMONIUM; THAPSIGARGIN; UNCLASSIFIED DRUG; VASODILATOR AGENT; WORTMANNIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRADYCARDIA; CALCIUM HOMEOSTASIS; CARDIOVASCULAR EFFECT; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; EUPHORBIA; EUPHORBIA HUMIFUSA; HEART RATE; HYPOTENSION; IN VIVO STUDY; MALE; NONHUMAN; RAT; SIGNAL TRANSDUCTION; SYSTOLIC BLOOD PRESSURE; VASCULAR RING; VASODILATATION;

ACETATES; ANIMALS; AORTA, THORACIC; BLOOD PRESSURE; CALCIUM; CYCLIC GMP; ENDOTHELIUM, VASCULAR; EUPHORBIA; HEART RATE; MALE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE III; PLANT EXTRACTS; POTASSIUM CHANNELS; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, ADRENERGIC; RECEPTORS, MUSCARINIC; VASODILATION; VASODILATOR AGENTS;

EUPHORBIA HUMIFUSA; RATTUS;

EID: 84879416420     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2013.05.025     Document Type: Article

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