Cardiovascular effects of Boophone disticha aqueous ethanolic extract on early maternally separated BALB/C mice

Journal of Ethnopharmacology

Volumn 148, Issue 2, 2013, Pages 379-385

  Pote, William ^a   Tagwireyi, Dexter ^a   Chinyanga, Herbert M ^a   Musara, Collin ^a   Nyandoro, George ^a   Chifamba, Jephat ^a   Nkomozepi, Pilani ^b  

^a UNIVERSITY OF ZIMBABWE   (Zimbabwe)

^b UNIVERSITY OF THE WITWATERSRAND   (South Africa)

Author keywords

Boophone disticha Maternal separation Anxiety disorders Blood pressure Heart rate

Indexed keywords

ANXIOLYTIC AGENT; BOOPHONE DISTICHA EXTRACT; DIAZEPAM; PLANT EXTRACT; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANXIETY DISORDER; ARTICLE; AUTONOMIC NERVOUS SYSTEM; BAGG ALBINO MOUSE; BLOOD PRESSURE; BOOPHONE DISTICHA; CARDIOVASCULAR EFFECT; CARDIOVASCULAR RESPONSE; CONTROLLED STUDY; EARLY LIFE STRESS; HEART RATE; IMMOBILIZATION STRESS; MATERNAL DEPRIVATION; MATERNAL STRESS; MEDICINAL PLANT; MOUSE; NONHUMAN;

ANIMALS; ANXIETY; AUTONOMIC NERVOUS SYSTEM; BLOOD PRESSURE; CARDIOVASCULAR SYSTEM; DIVORCE; ETHANOL; FEMALE; HEART RATE; LILIACEAE; MATERNAL DEPRIVATION; MEDICINE, AFRICAN TRADITIONAL; MICE; MICE, INBRED BALB C; PLANT EXTRACTS; STRESS, PSYCHOLOGICAL; WATER; ZIMBABWE;

BOOPHANE DISTICHA; MUS;

EID: 84879412638     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2013.03.001     Document Type: Article

References (49)

1. A.E. Adewusi, G. Fouche, and V. Steenkamp Cytotoxicity and acetylcholinesterase inhibitory activity of anisolated crinine alkaloid from Boophane disticha (Amaryllidaceae) Journal of Ethnopharmacology 2012 〈http://dx.doi.org/10.1016/j.jep.2012.07.011âŒ
2. Bastida, J., Berkov, S., Torras, L., Pigni N.B., de Andrade, J.P., Martínez, V., Codina, C., Viladomat, F., 2011. Chemical and biological aspects of Amaryllidaceae alkaloids. Recent Advances in Pharmaceutical Sciences, 2011: 65-100.
3. X.P. Bian, F.J. Seidler, and T.A. Slotkin Promotional role for glucocorticoids in the development of intracellular signalling: enhanced cardiac and renal adenylate cyclase reactivity to beta-adrenergic and non-adrenergic stimuli after low-dose fetal dexamethasone exposure Journal of Developmental Physiology 17 1992 289 297
4. J. Blanc, M.L. Grichois, and J.L. Elghozi Effects of clonidine on blood pressure and heart rate responses to an emotional stress in the rat: a spectral study Clinical and Experimental Pharmacology and Physiology 18 1991 711 717
5. E.W. Botha, C.P. Kahler, W.J. du Plooy, S.H. du Plooy, and L. Mathibe Effects of Boophone disticha on human neutrophils Journal of Ethnopharmacology 96 2005 385 388
6. L. Cheesman, J.J. Nair, and J. Van Staden Antibacterial activity of crinane alkaloids from Boophone disticha (Amaryllidaceae) Journal of Ethnopharmacology 140 2012 405 408
7. X. Chen, and J. Herbert Regional changes in c-fos expression in the basal forebrain and brainstem during adaptation to repeated stress: correlations with cardiovascular, hypothermic and endocrine responses Neuroscience 64 1995 675 685
8. Chingombe, P., Tagwireyi D., Gadaga L.L., 2010. Investigating the antidepressant-like activity of Boophone disticha after repeated daily dosing in a mouse model. University of Zimbabwe Library (unpublished results).
9. Chuma, Tagwireyi, D., Gadaga, L.L., 2010. Investigation of the anxiolytic-like activity of Boophane disticha extract in mice. University of Zimbabwe Library (unpublished results).
10. H. Cohen, and J. Benjamin Power spectrum analysis and cardiovascular morbidity in anxiety disorders Autonomic Neuroscience: Basic and Clinical 128 2006 1 8
11. C.R. Cole, E.H. Blackstone, F.G. Pashkow, C.E. Snader, and M.S. Lauer Heart rate recovery immediately after exercise as a predictor of mortality New England Journal of Medicine 342 1999 1351 1357
12. W.M. Daniels, C.Y. Pietersen, M.E. Carstens, and D.J. Stein Maternal separation in rats leads to anxiety-like behavior and a blunted ACTH response and altered neurotransmitter levels in response to a subsequent stressor Metabolic Brain Disease 19 2004 3 14
13. W.M.U. Daniels, L.R. Fairbairn, G. van Tilburg, C.R.E. McEvoy, M.J. Zigmond, V.A. Russell, and D.J. Stein Maternal separation alters nerve growth factor and corticosterone levels but not the DNA methylation status of the exon 17 glucocorticoid receptor promoter region Metabolic Brain Disease 24 2009 615 627
14. P.A.G.M. De Smet Some ethnopharmacological notes on African hallucinogens Journal of Ethnopharmacology 50 1996 141 146
15. W.J. Du Plooy, L. Swart, and G.W. Van Huysteen Poisoning with Boophane disticha: a forensic case Human and Experimental Toxicology 20 2001 277 278
16. J. Faure, J.D.K. Uys, L. Marais, D.J. Stein, and D.M.U. Daniels Early maternal separation followed by later stressors leads to dysregulation of the HPA-axis and increases in hippocampal NGF and NT-3 levels in a rat model Metabolic Brain Disease 21 2006 181 188
17. J. Faure, J.D.K. Uys, L. Marais, D.J. Stein, and W.M.U. Daniels Early maternal separation alters the response to traumatization resulting in increased levels of hippocampal neurotrophic factors Metabolic Brain Disease 22 2007 183 195
18. J.S. Floras, and B.L. Senn Absence of post exercise hypotension and sympathoinhibition in normal subject: additional evidence for increased sympathetic outflow in borderline hypertension Canadian Journal of Cardiology 72 1991 53 258
19. L.L. Gadaga, D. Tagwireyi, J. Dzangare, and C.F.B. Nhachi Acute oral toxicity and neurobehavioural toxicological effects of a hydroethanolic extract of Boophone disticha in rats Human and Experimental Toxicololgy 30 2011 972 980
20. E. Gaudet, J. Blanc, and J.L. Elghozi Role of angiotensin II and catecholamines in blood pressure variability responses to stress in SHR American Journal of Physiology 270 1996 R1265 R1272
21. C. Grillison, R. Duncko, M.F. Covington, L. Kopperman, and M.A. Kling Acute stress potentiates anxiety in humans Biological Psychiatry 62 2007 1183 1186
22. H. Hautch, and D. Stauffacher Die alkaloide von Buphane disticha (L.f.) Herb Helvetica Chimica Acta 44 1961 491 502
23. N. Igosheva, O. Klimova, T. Anishchenko, and V. Glover Prenatal stress alters cardiovascular responses in adult rats Journal of Physiology 557 2004 273 285
24. M. Kalinichev, K.W. Easterling, P.M. Plotsky, and S.G. Holtzman Long-lasting changes in stress-induced corticosterone responses and anxiety-like behaviors as a consequence of neonatal maternal separation in Long-Evans rats Pharmacology, Biochemistry and Behavior 73 2002 131 140
25. L. Kornel The role of vascular steroid receptors in the control of vascular contractility and peripheral vascular resistance The Journal of Steroid Biochemistry and Molecular Biology 45 1993 195 203
26. C.O. Ladd, R.L. Huot, K.V. Thrivikraman, C.B. Nemeroff, M.J. Meany, and P.M. Plotsky Long-term behavioural and neuroendocrine adaptations to adverse early experience Progress in Brain Research 122 2000 81 103
27. C.O. Ladd, M.J. Owens, and C.B. Nemeroff Persistent changes in corticotropin-releasing factor neuronal systems induced by maternal deprivation Endocrinology 137 1996 1212 1218
28. A.S. Loria, G. D'Angelo, D.M. Pollock, and J.S. Pollock Early life stress down regulates endothelin receptor expression and enhances acute stress-mediated blood pressure responses in adult rats American Journal of Physiology: Regulation Integration Comparative Physiology 299 2010 R185 R191
29. B.A. Larsen, and N.J.S. Christenfeld Cardiovascular disease and psychiatric comorbidity: the potential role of perseverative cognition Cardiovascular, Psychiatry and Neurology 2009 1 8
30. G. Mancia, and G. Parati The role of blood pressure variability in end-organ damage Journal of Hypertension 6 2003 S17 S23
31. L. Marais, S.J. Van Rensburg, J.M. Van Zyl, D.J. Stein, and W.M.U. Daniels Maternal separation of rat pups increases the risk of developing depressive-like behavior after subsequent chronic stress by altering corticosteorne and neurotrophin levels in the hippocampus Neurochemical Research 61 2008 106 112
32. Mungadzi, E., Tagwireyi D., and Gadaga L.L., 2008. Investigation of anxiolytic and memory enhancing properties of Boophone disticha in a rat model. University of Zimbabwe Library (unpublished results).
33. Musarira, S., Tagwireyi D., and Gadaga L.L., 2011. Effects of a hydroethanolic extract of Boophone disticha bulb in behavioral models of anxiety in mice. University of Zimbabwe (unpublished results).
34. J.S. Neergaard, J. Andersen, M.E. Pedersen, G.I. Stafford, J. Van Staden, and A.K. Jäger Alkaloids from Boophone disticha with affinity to the serotonin transporter South African Journal of Botany 75 2009 371 374
35. N.D. Nielsen, M. Sandager, G.I. Stafford, J. Van Staden, and A.K. Jäger Screening of indigenous plants from South Africa for affinity to the serotonin reuptake transport protein Journal of Ethnopharmacology 94 2004 159 163
36. M.E. Pedersen, H.T. Vestergaard, G.I. Stafford, J. van Staden, and A.K. Jäger The effect of extracts of Searsia species on epileptiform activity in slices of the mouse cerebral cortex Journal of Ethnopharmacology 119 2008 538 541
37. M.E. Pedersen, B. Szewczyk, K. Stachowicz, J. Wieronska, J. Andersen, G.I. Stafford, J. van Staden, A. Pilc, and A.K. Jäger Effects of South African traditional medicine in animal models for depression Journal of Ethnopharmacology 119 2008 542 548
38. P.M. Plotsky, and M.J. Meany Early, postnatal experience alters hypothalamic corticotrophin-releasing factor (CRF) mRNA, median eminence CRF content and stress-induced release in adult rats Molecular Brain Research 18 1993 195 200
39. P.H. Provencher, J. Saltis, and J.W. Funder Glucocorticoids but not mineralocorticoids modulate endothelin-1 and angiotensin II binding in SHR vascular smooth muscle cells The Journal of Steroid Biochemistry and Molecular Biology 52 1998 219 225
40. C.R. Pryce, and J. Feldon Long-term neurobehavioral impact of the postnatal environment in rats: manipulations, effects, and mediating mechanisms Neuroscience Biobehavioural Review 27 2003 57 71
41. M. Sandager, N.D. Nielsen, G.I. Stafford, J. van Staden, and A.K. Jäger Alkaloids from Boophane disticha with affinity to the serotonin transporter in rat brain Journal of Ethnopharmacology 98 2005 367 370
42. H.A. Slotten, M. Kalinichev, J.J. Hagen, C.A. Marsden, and K.C. Fona Long-lasting changes in behavioural and neuroendocrine indices in the rat following neonatal maternal separation: gender dependent effects Brain Research 1097 2006 123 132
43. G.I. Stafford, M.E. Pedersen, J. Van Staden, and A.K. Jäger Review on plants with CNS-effects used in traditional South African medicine against mental diseases Journal of Ethnopharmacology 119 2008 513 537
44. T.L. Schwartz, and N. Nihalani Tiagabine in anxiety disorders Expert Opinion in Pharmacotherapy 7 2006 1977 1987
45. F. Viladomat, J. Bastida, C. Codina, J.J. Nair, and W.E. Campbell Alkaloids of the South African Amaryllidaceae, recent research development Phytochemistry 1 1997 131 171
46. G. Volkmar, J. Tank, M. Obst, R. Plehm, K.J. Blumer, A. Diedrich, J. Jordan, and F.C. Luft Autonomic nervous system and blood pressure in RGS2-deficient mice American Journal of Physiology - Regulatory, integrative and comparative Physiology 228 2005 R1132 R1142
47. B.R. Walker, and B.C. Williams Corticosteroids and vascular tone: mapping the messenger maze Clinical Science (London) 82 1992 597 605
48. J. Watanabe, M. Thamilarasan, E.H. Blackstone, J.D. Thomas, and M.S. Lauer Heart rate recovery immediately after treadmill exercise and left ventricular systolic dysfunction as predictors of mortality: the case of stress echocardiography Circulation 104 2001 1911 1916
49. Zulu, D., Tagwireyi, D., Gadaga, L.L., 2011. Solvent extraction and chromatographic characterization of isoquinoline alkaloids from the bulb of Boophone disticha. University of Zimbabwe Library (unpublished results).