A multi-institutional, phase II open-label study of ganitumab (AMG 479) in advanced carcinoid and pancreatic neuroendocrine tumours
Strosberg, J. et al. A multi-institutional, phase II open-label study of ganitumab (AMG 479) in advanced carcinoid and pancreatic neuroendocrine tumours. Endocr. Relat. Cancer 20, 383-390 (2013).
Targeted therapies: Good news for advanced-stage pancreatic neuroendocrine tumors
Spiegel, A. M. & Libutti, S. K. Targeted therapies: Good news for advanced-stage pancreatic neuroendocrine tumors. Nat. Rev. Clin. Oncol. 8, 258-259 (2011).
The insulin-like growth factor receptor 1 is a promising target for novel treatment approaches in neuroendocrine gastrointestinal tumours
Höpfner, M., Baradari, V., Huether, A., Schöfl, C. & Scherübl, H. The insulin-like growth factor receptor 1 is a promising target for novel treatment approaches in neuroendocrine gastrointestinal tumours. Endocr. Relat. Cancer 13, 135-149 (2006).
Differential expression of alternatively spliced mRNA forms of the insulinlike growth factor 1 receptor in human neuroendocrine tumors
Vitale, L. et al. Differential expression of alternatively spliced mRNA forms of the insulinlike growth factor 1 receptor in human neuroendocrine tumors. Oncol. Rep. 15, 1249-1256 (2006).
Phase I, pharmacokinetic, and pharmacodynamic study of AMG 479, a fully human monoclonal antibody to insulin-like growth factor receptor 1
Tolcher, A. W. et al. Phase I, pharmacokinetic, and pharmacodynamic study of AMG 479, a fully human monoclonal antibody to insulin-like growth factor receptor 1. J. Clin. Oncol. 27, 5800-5807 (2009).
A phase 2 study of the insulin-like growth factor-1 receptor inhibitor MK-0646 in patients with metastatic, well-differentiated neuroendocrine tumors
Reidy-Lagunes, D. L. et al. A phase 2 study of the insulin-like growth factor-1 receptor inhibitor MK-0646 in patients with metastatic, well-differentiated neuroendocrine tumors. Cancer 118, 4795-4800 (2012).
Recapitulation of pancreatic neuroendocrine tumours in human multiple endocrine neoplasia type i syndrome via Pdx1-directed inactivation of Men1
Shen, H. C. et al. Recapitulation of pancreatic neuroendocrine tumours in human multiple endocrine neoplasia type I syndrome via Pdx1-directed inactivation of Men1. Cancer Res. 69, 1858-1866 (2009).
Pasireotide (SOM230) is effective for the treatment of pancreatic neuroendocrine tumours (PNETs) in a multiple endocrine neoplasia type 1(MEN1) conditional knockout mouse model
Quinn, T. J. et al. Pasireotide (SOM230) is effective for the treatment of pancreatic neuroendocrine tumours (PNETs) in a multiple endocrine neoplasia type 1(MEN1) conditional knockout mouse model. Surgery 152, 1068-1077 (2012).