Dengue virus tetra-epitope peptide expressed in lettuce chloroplasts for potential use in dengue diagnosis

Applied Microbiology and Biotechnology

Volumn 97, Issue 13, 2013, Pages 5721-5729

  Maldaner, Franciele Roberta ^a   Aragão, Francisco José Lima ^b   Dos Santos, Flávia Barreto ^c   Franco, Octavio Luiz ^d   Da Rocha Queiroz Lima, Monique ^c   De Oliveira Resende, Renato ^a   Vasques, Raquel Medeiros ^d   Nagata, Tatsuya ^a  

^a UNIVERSITY OF BRASILIA   (Brazil)

^b EMBRAPA RECURSOS GENÉTICOS E BIOTECNOLOGIA   (Brazil)

^c INSTITUTO OSWALDO CRUZ   (Brazil)

^d UNIVERSIDADE CATÓLICA DE BRASÍLIA   (Brazil)

Author keywords

Dengue diagnostic; Dengue virus; Tetra epitope antigen; Transplastomic plant

Indexed keywords

DENGUE DIAGNOSTIC; DENGUE VIRUS; HEALTHY INDIVIDUALS; LARGE-SCALE PRODUCTION; NON-SPECIFIC INTERACTIONS; PLANT EXPRESSION SYSTEMS; PLASTID TRANSFORMATION; TRANSPLASTOMIC PLANT;

AMINO ACIDS; DIAGNOSIS; PEPTIDES; RECOMBINANT PROTEINS; VIRUSES;

EPITOPES;

EPITOPE; GLYCINE; PEPTIDES AND PROTEINS; TETRAEPITOPE PEPTIDE; UNCLASSIFIED DRUG;

ANTIGEN; BIOASSAY; DENGUE FEVER; DISEASE INCIDENCE; DISEASE VECTOR; PEPTIDE; PLASTID; PROTEIN; VACCINATION;

ARTICLE; CHLOROPLAST; CONTROLLED STUDY; CROSS REACTION; DENGUE; DENGUE VIRUS; DIAGNOSTIC TEST ACCURACY STUDY; DIAGNOSTIC VALUE; HUMAN; IMMUNOREACTIVITY; LETTUCE; MAJOR CLINICAL STUDY; NONHUMAN; NUCLEOTIDE SEQUENCE; PLASTID; PROTEIN DOMAIN; PROTEIN EXPRESSION; SENSITIVITY AND SPECIFICITY; SEROTYPE; STRUCTURE ANALYSIS; YELLOW FEVER;

ANTIBODIES, VIRAL; ANTIGENS, VIRAL; CHLOROPLASTS; CROSS REACTIONS; DENGUE; DENGUE VIRUS; EPITOPES; GENETIC VECTORS; HUMANS; LETTUCE; MOLECULAR SEQUENCE DATA; PLANTS, GENETICALLY MODIFIED; RECOMBINANT PROTEINS; RNA, VIRAL; SENSITIVITY AND SPECIFICITY; SEQUENCE ANALYSIS, DNA; VIRAL ENVELOPE PROTEINS;

DENGUE VIRUS; LACTUCA; TETRA;

EID: 84879410252     PISSN: 01757598     EISSN: 14320614     Source Type: Journal    
DOI: 10.1007/s00253-013-4918-6     Document Type: Article

References (41)

1. Anandarao R, Swaminathan S, Fernando S, Jana AM, Khanna N (2006) Recombinant multiepitope protein for early detection of dengue infections. Clin Vaccine Immunol 13:59-67
2. Aragão FJL, Brasileiro ACM, Ribeiro SG, Smith FD, Sanford JC, Faria JC, Rech EL (1996) Inheritance of foreign genes in transgenic bean (Phaseolus vulgaris) co-transformed via particle bombardment. Theor Appl Genet 93:142-150. doi: 10.1007/BF00225739
3. Batra G, Nemani SK, Tyagi P, Swaminathan S, Khanna N (2011) Evaluation of envelope domain III-based single chimeric tetravalent antigen and monovalent antigen mixtures for the detection of anti-dengue antibodies in human sera. BMC Infect Dis 11:64
4. Beasley DW, Aaskov JG (2001) Epitopes on the dengue 1 virus envelope protein recognized by neutralizing IgM monoclonal antibodies. Virology 279:447-458
5. Beaumier CM, Mathew A, Bashyam HS, Rothman AL (2008) Cross-reactive memory CD8(+) T cells alter the immune response to heterologous secondary dengue virus infections in mice in a sequence-specific manner. J Infect Dis 197:608-617
6. Cuzzubbo AJ, Endy TP, Nisalak A, Kalayanarooj S, Vaughn DW, Ogata SA, Clements DE, Devine PL (2001) Use of recombinant envelope proteins for serological diagnosis of Dengue virus infection in an immunochromatographic assay. Clin Diagn Lab Immunol 8:1150-1155
7. Daniell H, Khan MS, Allison L (2002) Milestones in chloroplast genetic engineering: an environmentally friendly era in biotechnology. Trends Plant Sci 7:84-91
8. Davoodi-Semiromi A, Schreiber M, Nalapalli S, Verma D, Singh ND, Banks RK, Chakrabarti D, Daniell H (2010) Chloroplast-derived vaccine antigens confer dual immunity against cholera and malaria by oral or injectable delivery. Plant Biotechnol J 8:223-242
9. DeLano W (2002) The PyMOL molecular graphics system. Version 1.2r3pre. LLC, Schrödinger
10. dos Santos FB, Miagostovich MP, Nogueira RM, Schatzmayr HG, Riley LW, Harris E (2004) Analysis of recombinant dengue virus polypeptides for dengue diagnosis and evaluation of the humoral immune response. AmJTrop Med Hyg 71:144-152
11. Doyle JJ, Doyle JL (1987) A rapid DNA isolation procedure for small quantities of fresh leaf tissue. Phytochem Bull 19:11-15
12. Eswar N, Webb B, Marti-Renom MA, Madhusudhan MS, Eramian D, Shen MY, Pieper U, Sali A (2006) Comparative protein structure modeling using Modeller. Curr Protoc Bioinformatics 15:5.6.1-5.6.30. doi: 10.1002/0471250953.bi0506s15
13. Falconar AK (1999) Identification of an epitope on the dengue virus membrane (M) protein defined by cross-protective monoclonal antibodies: design of an improved epitope sequence based on common determinants present in both envelope (E and M) proteins. Arch Virol 144:2313-2330
14. Fry SR, Meyer M, Semple MG, Simmons CP, Sekaran SD, Huang JX, McElnea C, Huang CY, Valks A, Young PR, Cooper MA (2011) The diagnostic sensitivity of dengue rapid test assays is significantly enhanced by using a combined antigen and antibody testing approach. PLoS Negl Trop Dis 5:e1199. doi: 10.1371/journal.pntd.0001199PNTD-D-10-00128
15. Ginalski K, Elofsson A, Fischer D, Rychlewski L (2003) 3D-Jury: a simple approach to improve protein structure predictions. Bioinformatics 19:1015-1018
16. Goncalvez AP, Purcell RH, Lai CJ (2004) Epitope determinants of a chimpanzee Fab antibody that efficiently cross-neutralizes dengue type 1 and type 2 viruses map to inside and in close proximity to fusion loop of the dengue type 2 virus envelope glycoprotein. J Virol 78:12919-12928
17. Gromowski GD, Barrett AD (2007) Characterization of an antigenic site that contains a dominant, type-specific neutralization determinant on the envelope protein domain III (ED3) of dengue 2 virus. Virology 366:349-360
18. Kanagaraj AP, Verma D, Daniell H (2011) Expression of dengue-3 premembrane and envelope polyprotein in lettuce chloroplasts. Plant Mol Biol 76:323-333
19. Kanamoto H, Yamashita A, Asao H, Okumura S, Takase H, Hattori M, Yokota A, Tomizawa K (2006) Efficient and stable transformation of Lactuca sativa L. cv. Cisco (lettuce) plastids. Transgenic Res 15:205-217
20. Kim TG, Kim MY, Yang MS (2010) Cholera toxin B subunit-domain III of dengue virus envelope glycoprotein E fusion protein production in transgenic plants. Protein Expr Purif 74(2):236-241
21. Kurane I (2007) Dengue hemorrhagic fever with special emphasis on immunopathogenesis. Comp Immunol Microbiol 30:329-340
22. Lai CJ, Goncalvez AP, Men R, Wernly C, Donau O, Engle RE, Purcell RH (2007) Epitope determinants of a chimpanzee dengue virus type 4 (DENV-4)-neutralizing antibody and protection against DENV-4 challenge in mice and rhesus monkeys by passively transferred humanized antibody. J Virol 81:12766-12774
23. Lanciotti RS, Calisher CH, Gubler DJ, Chang GJ, Vorndam AV (1992) Rapid detection and typing of dengue viruses from clinical samples by using reverse transcriptase-polymerase chain reaction. J Clin Microbiol 30:545-551
24. Lim S, Ashida H, Watanabe R, Inai K, Kim YS, Mukougawa K, Fukuda H, Tomizawa K, Ushiyama K, Asao H, Tamoi M, Masutani H, Shigeoka S, Yodoi J, Yokota A (2011) Production of biologically active human thioredoxin 1 protein in lettuce chloroplasts. Plant Mol Biol 76:335-344
25. Lima Mda R, Nogueira RM, Schatzmayr HG, dos Santos FB (2010) Comparison of three commercially available dengue NS1 antigen capture assays for acute diagnosis of dengue in Brazil. PLoS Negl Trop Dis 4:e738
26. Lisova O, Hardy F, Petit V, Bedouelle H (2007) Mapping to completeness and transplantation of a group-specific, discontinuous, neutralizing epitope in the envelope protein of dengue virus. J Gen Virol 88:2387-2397
27. Lossl AG, Waheed MT (2011) Chloroplast-derived vaccines against human diseases: achievements, challenges and scopes. Plant Biotechnol J 9:527-539
28. Martinez CA, Topal E, Giulietti AM, Talou JR, Mason H (2010) Exploring different strategies to express Dengue virus envelope protein in a plant system. Biotechnol Lett 32:867-875
29. Modis Y, Ogata S, Clements D, Harrison SC (2003) A ligand-binding pocket in the dengue virus envelope glycoprotein. Proc Natl Acad Sci U S A 100:6986-6991. doi: 10.1073/pnas.08321931000832193100
30. Mondini A, Cardeal ILS, Lázaro E, Nunes SH, Moreira CC, Rahal P, Maia IL, Franco C, Góngora DVN, Góngora-Rubio F, Cabrera EMS, Figueiredo LTM, Fonseca FG, Bronzoni RVM, Chiaravalloti-Neto F, Nogueira ML (2007) Saint Louis encephalitis virus, Brazil. Emerg Infect Dis 13:176-178
31. Peeling RW, Artsob H, Pelegrino JL, Buchy P, Cardosa MJ, Devi S, Enria DA, Farrar J, Gubler DJ, Guzman MG, Halstead SB, Hunsperger E, Kliks S, Margolis HS, Nathanson CM, Nguyen VC, Rizzo N, Vazquez S, Yoksan S (2010) Evaluation of diagnostic tests: dengue. Nat Rev Microbiol 8:S30-S37. doi: 10.1038/nrmicro2459
32. Rodrigues S, Nunes MRT, Casseb SMM, Prazeres ASC, Rodrigues DSG, Silva MO, Cruz ACR, Tavares-Neto JCT, Vasconcelos PFC (2010) Molecular epidemiology of Saint Louis encephalitis virus in the Brazilian Amazon: genetic divergence and dispersal. J Gen Virol 91:2420-2427
33. Roehrig JT, Johnson AJ, Hunt AR, Bolin RA, Chu MC (1990) Antibodies to dengue 2 virus E-glycoprotein synthetic peptides identify antigenic conformation. Virology 177:668-675
34. Roehrig JT, Bolin RA, Kelly RG (1998) Monoclonal antibody mapping of the envelope glycoprotein of the dengue 2 virus, Jamaica. Virology 246:317-328
35. Saejung W, Fujiyama K, Takasaki T, Ito M, Hori K, Malasit P, Watanabe Y, Kurane I, Seki T (2007) Production of dengue 2 envelope domain III in plant using TMV-based vector system. Vaccine 25:6646-6654
36. Sali A, Blundell TL (1993) Comparative protein modeling by satisfaction of spatial restraints. J Mol Biol 234:779-815
37. Sumathi K, Ananthalakshmi P, Roshan MN, Sekar K (2006) 3dSS: 3D structural superposition. Nucleic Acids Res 34:W128-W132. doi: 10.1093/nar/gkl036
38. van der Schaar HM, Wilschut JC, Smit JM (2009) Role of antibodies in controlling dengue virus infection. Immunobiology 214:613-629
39. WHO (2009) Fact sheet no 117, dengue and dengue haemorrhagic fever. World Health Organization, Geneva
40. Wiederstein M, Sippl MJ (2007) ProSA-web: interactive web service for the recognition of errors in three-dimensional structures of proteins. Nucleic Acids Res 35:W407-W410. doi: 10.1093/nar/gkm290
41. Wilkins MR, Gasteiger E, Bairoch A, Sanchez JC, Williams KL, Appel RD, Hochstrasser DF (1999) Protein identification and analysis tools in the ExPASy server. Methods Mol Biol 112:531-552 Tecnológico