-
1
-
-
78149233272
-
Cancer vaccines in glioma: How to balance the challenges of small trials, efficiency, and potential adverse events
-
Lowenstein PR. (2010). Cancer vaccines in glioma: how to balance the challenges of small trials, efficiency, and potential adverse events. J Clin Oncol 28:4670-4673.
-
(2010)
J Clin Oncol
, vol.28
, pp. 4670-4673
-
-
Lowenstein, P.R.1
-
2
-
-
65349112511
-
TRAIL gene therapy: From preclinical development to clinical application
-
Griffith TS, B Stokes, TA Kucaba, JK Earel, Jr., RL Van-Oosten, EL Brincks and LA Norian. (2009). TRAIL gene therapy: from preclinical development to clinical application. Curr Gene Ther 9:9-19.
-
(2009)
Curr Gene Ther
, vol.9
, pp. 9-19
-
-
Griffith, T.S.1
Stokes, B.2
Kucaba, T.A.3
Earel Jr., J.K.4
Van-Oosten, R.L.5
Brincks, E.L.6
Norian, L.A.7
-
3
-
-
62449168519
-
TRAIL agonists on clinical trials for cancer therapy: The promises and the challenges
-
Bellail AC, L Qi, P Mulligan, V Chhabra and C Hao. (2009). TRAIL agonists on clinical trials for cancer therapy: the promises and the challenges. Rev Recent Clin Trials 4:34-41.
-
(2009)
Rev Recent Clin Trials
, vol.4
, pp. 34-41
-
-
Bellail, A.C.1
Qi, L.2
Mulligan, P.3
Chhabra, V.4
Hao, C.5
-
4
-
-
42749092258
-
TRAIL receptor-targeted therapeutics: Resistance mechanisms and strategies to avoid them
-
Thorburn A, K Behbakht and H Ford. (2008). TRAIL receptor-targeted therapeutics: resistance mechanisms and strategies to avoid them. Drug Resist Updat 11:17-24.
-
(2008)
Drug Resist Updat
, vol.11
, pp. 17-24
-
-
Thorburn, A.1
Behbakht, K.2
Ford, H.3
-
5
-
-
0035050960
-
Differential hepatocyte toxicity of recombinant Apo2L/TRAIL versions
-
Lawrence D, Z Shahrokh, S Marsters, K Achilles, D Shih, B Mounho, K Hillan, K Totpal, L DeForge, et al. (2001). Differential hepatocyte toxicity of recombinant Apo2L/TRAIL versions. Nat Med 7:383-385.
-
(2001)
Nat Med
, vol.7
, pp. 383-385
-
-
Lawrence, D.1
Shahrokh, Z.2
Marsters, S.3
Achilles, K.4
Shih, D.5
Mounho, B.6
Hillan, K.7
Totpal, K.8
Deforge, L.9
-
6
-
-
33646393778
-
Preclinical differentiation between apparently safe and potentially hepatotoxic applications of TRAIL either alone or in combination with chemotherapeutic drugs
-
Ganten TM, R Koschny, J Sykora, H Schulze-Bergkamen, P Buchler, TL Haas, MB Schader, A Untergasser, W Stremmel and H Walczak. (2006). Preclinical differentiation between apparently safe and potentially hepatotoxic applications of TRAIL either alone or in combination with chemotherapeutic drugs. Clin Cancer Res 12:2640-2646.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 2640-2646
-
-
Ganten, T.M.1
Koschny, R.2
Sykora, J.3
Schulze-Bergkamen, H.4
Buchler, P.5
Haas, T.L.6
Schader, M.B.7
Untergasser, A.8
Stremmel, W.9
Walczak, H.10
-
7
-
-
57749097095
-
TRAIL resistance of breast cancer cells is associated with constitutive endocytosis of death receptors 4 and 5
-
Zhang Y and B Zhang. (2008). TRAIL resistance of breast cancer cells is associated with constitutive endocytosis of death receptors 4 and 5. Mol Cancer Res 6:1861-1871.
-
(2008)
Mol Cancer Res
, vol.6
, pp. 1861-1871
-
-
Zhang, Y.1
Zhang, B.2
-
8
-
-
22044441646
-
Accelerated degradation of caspase-8 protein correlates with TRAIL resistance in a DLD1 human colon cancer cell line
-
DOI 10.1593/neo.04688
-
Zhang L, H Zhu, F Teraishi, JJ Davis, W Guo, Z Fan and B Fang. (2005). Accelerated degradation of caspase-8 protein correlates with TRAIL resistance in a DLD1 human colon cancer cell line. Neoplasia 7:594-602. (Pubitemid 40967760)
-
(2005)
Neoplasia
, vol.7
, Issue.6
, pp. 594-602
-
-
Zhang, L.1
Zhu, H.2
Teraishi, F.3
Davis, J.J.4
Guo, W.5
Fan, Z.6
Fang, B.7
-
9
-
-
78651097203
-
Identification of c-FLIP(L) and c-FLIP(S) as critical regulators of death receptorinduced apoptosis in pancreatic cancer cells
-
Haag C, D Stadel, S Zhou, MG Bachem, P Moller, KM Debatin and S Fulda. (2010). Identification of c-FLIP(L) and c-FLIP(S) as critical regulators of death receptorinduced apoptosis in pancreatic cancer cells. Gut 60:225-237.
-
(2010)
Gut
, vol.60
, pp. 225-237
-
-
Haag, C.1
Stadel, D.2
Zhou, S.3
Bachem, M.G.4
Moller, P.5
Debatin, K.M.6
Fulda, S.7
-
10
-
-
56249143130
-
Targeting multiple pathways in gliomas with stem cell and viral delivered S-TRAIL and Temozolomide
-
Hingtgen S, X Ren, E Terwilliger, M Classon, R Weissleder and K Shah. (2008). Targeting multiple pathways in gliomas with stem cell and viral delivered S-TRAIL and Temozolomide. Mol Cancer Ther 7:3575-3585.
-
(2008)
Mol Cancer Ther
, vol.7
, pp. 3575-3585
-
-
Hingtgen, S.1
Ren, X.2
Terwilliger, E.3
Classon, M.4
Weissleder, R.5
Shah, K.6
-
11
-
-
77951894266
-
Phase 1b study of dulanermin (recombinant human Apo2L/TRAIL) in combination with paclitaxel, carboplatin, and bevacizumab in patients with advanced non-squamous non-small-cell lung cancer
-
Soria JC, E Smit, D Khayat, B Besse, X Yang, CP Hsu, D Reese, J Wiezorek and F Blackhall. (2010). Phase 1b study of dulanermin (recombinant human Apo2L/TRAIL) in combination with paclitaxel, carboplatin, and bevacizumab in patients with advanced non-squamous non-small-cell lung cancer. J Clin Oncol 28:1527-1533.
-
(2010)
J Clin Oncol
, vol.28
, pp. 1527-1533
-
-
Soria, J.C.1
Smit, E.2
Khayat, D.3
Besse, B.4
Yang, X.5
Hsu, C.P.6
Reese, D.7
Wiezorek, J.8
Blackhall, F.9
-
12
-
-
78651385352
-
A dual PI3K/mTOR inhibitor, PI-103, cooperates with stem cell-delivered TRAIL in experimental glioma models
-
Bagci-Onder T, H Wakimoto, M Anderegg, C Cameron and K Shah. (2010). A dual PI3K/mTOR inhibitor, PI-103, cooperates with stem cell-delivered TRAIL in experimental glioma models. Cancer Res 71:154-163.
-
(2010)
Cancer Res
, vol.71
, pp. 154-163
-
-
Bagci-Onder, T.1
Wakimoto, H.2
Anderegg, M.3
Cameron, C.4
Shah, K.5
-
13
-
-
79955992274
-
Bortezomib primes neuroblastoma cells for TRAIL-induced apoptosis by linking the death receptor to the mitochondrial pathway
-
Naumann I, R Kappler, D von Schweinitz, KM Debatin and S Fulda. (2011). Bortezomib primes neuroblastoma cells for TRAIL-induced apoptosis by linking the death receptor to the mitochondrial pathway. Clin Cancer Res 17:3204-3218.
-
(2011)
Clin Cancer Res
, vol.17
, pp. 3204-3218
-
-
Naumann, I.1
Kappler, R.2
Von Schweinitz, D.3
Debatin, K.M.4
Fulda, S.5
-
14
-
-
84869087920
-
Histone deacetylase inhibitors sensitize glioblastoma cells to TRAIL-induced apoptosis by c-myc-mediated downregulation of cFLIP
-
Bangert A, S Cristofanon, I Eckhardt, BA Abhari, S Kolodziej, S Hacker, SH Vellanki, J Lausen, KM Debatin and S Fulda. (2012). Histone deacetylase inhibitors sensitize glioblastoma cells to TRAIL-induced apoptosis by c-myc-mediated downregulation of cFLIP. Oncogene 31:4677-4688.
-
(2012)
Oncogene
, vol.31
, pp. 4677-4688
-
-
Bangert, A.1
Cristofanon, S.2
Eckhardt, I.3
Abhari, B.A.4
Kolodziej, S.5
Hacker, S.6
Vellanki, S.H.7
Lausen, J.8
Debatin, K.M.9
Fulda, S.10
-
15
-
-
51349083548
-
Identification of a novel switch in the dominant forms of cell adhesion-mediated drug resistance in glioblastoma cells
-
Westhoff MA, S Zhou, MG Bachem, KM Debatin and S Fulda. (2008). Identification of a novel switch in the dominant forms of cell adhesion-mediated drug resistance in glioblastoma cells. Oncogene 27:5169-5181.
-
(2008)
Oncogene
, vol.27
, pp. 5169-5181
-
-
Westhoff, M.A.1
Zhou, S.2
Bachem, M.G.3
Debatin, K.M.4
Fulda, S.5
-
16
-
-
0035985057
-
Structural and functional diversity of connexin genes in the mouse and human genome
-
DOI 10.1515/BC.2002.076
-
Willecke K, J Eiberger, J Degen, D Eckardt, A Romualdi, M Guldenagel, U Deutsch and G Sohl. (2002). Structural and functional diversity of connexin genes in the mouse and human genome. Biol Chem 383:725-737. (Pubitemid 34649891)
-
(2002)
Biological Chemistry
, vol.383
, Issue.5
, pp. 725-737
-
-
Willecke, K.1
Eiberger, J.2
Degen, J.3
Eckardt, D.4
Romualdi, A.5
Guldenagel, M.6
Deutsch, U.7
Sohl, G.8
-
17
-
-
33746483243
-
Carbenoxolone inhibits junctional transfer and upregulates Connexin43 expression by a protein kinase A-dependent pathway
-
DOI 10.1002/jcb.20870
-
Sagar GD and DM Larson. (2006). Carbenoxolone inhibits junctional transfer and upregulates Connexin43 expression by a protein kinase A-dependent pathway. J Cell Biochem 98:1543-1551. (Pubitemid 44141858)
-
(2006)
Journal of Cellular Biochemistry
, vol.98
, Issue.6
, pp. 1543-1551
-
-
Sagar, G.D.V.1
Larson, D.M.2
-
18
-
-
25444505690
-
Contribution of gap junctional communication between tumor cells and astroglia to the invasion of the brain parenchyma by human glioblastomas
-
Oliveira R, C Christov, JS Guillamo, S de Bouard, S Palfi, L Venance, M Tardy and M Peschanski. (2005). Contribution of gap junctional communication between tumor cells and astroglia to the invasion of the brain parenchyma by human glioblastomas. BMC Cell Biol 6:7.
-
(2005)
BMC Cell Biol
, vol.6
, pp. 7
-
-
Oliveira, R.1
Christov, C.2
Guillamo, J.S.3
De Bouard, S.4
Palfi, S.5
Venance, L.6
Tardy, M.7
Peschanski, M.8
-
19
-
-
84855272942
-
-
online Drugs.com. Carbenoxolone. Available from (Accessed on 18 March, 2013)
-
Drug information online. Drugs.com. (2011). Carbenoxolone. Available fromwww.drugs.com/international/carbenoxolone. html. (Accessed on 18 March, 2013).
-
(2011)
Drug Information
-
-
-
20
-
-
0023795464
-
Glycyrrhetinic acid derivatives: A novel class of inhibitors of gap-junctional intercellular communication. Structure-activity relationships
-
Davidson JS and IM Baumgarten. (1988). Glycyrrhetinic acid derivatives: a novel class of inhibitors of gap-junctional intercellular communication. Structure-activity relationships. J Pharmacol Exp Ther 246:1104-1107.
-
(1988)
J Pharmacol Exp Ther
, vol.246
, pp. 1104-1107
-
-
Davidson, J.S.1
Baumgarten, I.M.2
-
21
-
-
0037019337
-
Pluripotency of mesenchymal stem cells derived from adult marrow
-
DOI 10.1038/nature00870
-
Jiang Y, BN Jahagirdar, RL Reinhardt, RE Schwartz, CD Keene, XR Ortiz-Gonzalez, M Reyes, T Lenvik, T Lund, et al. (2002). Pluripotency of mesenchymal stem cells derived from adult marrow. Nature 418:41-49. (Pubitemid 34742565)
-
(2002)
Nature
, vol.418
, Issue.6893
, pp. 41-49
-
-
Jiang, Y.1
Jahagirdar, B.N.2
Reinhardt, R.L.3
Schwartz, R.E.4
Keene, C.D.5
Ortiz-Gonzalez, X.R.6
Reyes, M.7
Lenvik, T.8
Lund, T.9
Blackstad, M.10
Du, J.11
Aldrich, S.12
Lisberg, A.13
Low, W.C.14
Lergaespada, D.A.15
Verfaillie, C.M.16
-
22
-
-
77956697181
-
Homing pathways of mesenchymal stromal cells (MSCs) and their role in clinical applications
-
Deak E, E Seifried and R Henschler. (2010). Homing pathways of mesenchymal stromal cells (MSCs) and their role in clinical applications. Int Rev Immunol 29:514-529.
-
(2010)
Int Rev Immunol
, vol.29
, pp. 514-529
-
-
Deak, E.1
Seifried, E.2
Henschler, R.3
-
23
-
-
67649625292
-
Matrix metalloproteinase 1 is necessary for the migration of human bone marrow-derived mesenchymal stem cells toward human glioma
-
Ho IA, KY Chan, WH Ng, CM Guo, KM Hui, P Cheang and PY Lam. (2009). Matrix metalloproteinase 1 is necessary for the migration of human bone marrow-derived mesenchymal stem cells toward human glioma. Stem Cells 27:1366-1375.
-
(2009)
Stem Cells
, vol.27
, pp. 1366-1375
-
-
Ho, I.A.1
Chan, K.Y.2
Ng, W.H.3
Guo, C.M.4
Hui, K.M.5
Cheang, P.6
Lam, P.Y.7
-
24
-
-
79952899402
-
TRAIL-transduced multipotent mesenchymal stromal cells (TRAIL-MSC) overcome TRAIL resistance in selected CRC cell lines in vitro and in vivo
-
Mueller LP, J Luetzkendorf, M Widder, K Nerger, H Caysa and T Mueller. (2011). TRAIL-transduced multipotent mesenchymal stromal cells (TRAIL-MSC) overcome TRAIL resistance in selected CRC cell lines in vitro and in vivo. Cancer Gene Ther 18:229-239.
-
(2011)
Cancer Gene Ther
, vol.18
, pp. 229-239
-
-
Mueller, L.P.1
Luetzkendorf, J.2
Widder, M.3
Nerger, K.4
Caysa, H.5
Mueller, T.6
-
25
-
-
49549119548
-
HSV-1 amplicon viral vectormediated gene transfer to human bone marrow-derived mesenchymal stem cells
-
Ho IA, KY Chan, L Miao, WS Shim, CM Guo, P Cheang, KM Hui and PY Lam. (2008). HSV-1 amplicon viral vectormediated gene transfer to human bone marrow-derived mesenchymal stem cells. Cancer Gene Ther 15:553-562.
-
(2008)
Cancer Gene Ther
, vol.15
, pp. 553-562
-
-
Ho, I.A.1
Chan, K.Y.2
Miao, L.3
Shim, W.S.4
Guo, C.M.5
Cheang, P.6
Hui, K.M.7
Lam, P.Y.8
-
26
-
-
84857666745
-
Establishment, maintenance and in vitro and in vivo applications of primary human glioblastoma multiforme (GBM) xenograft models for translational biology studies and drug discovery
-
Unit 14 16
-
Carlson BL, JL Pokorny, MA Schroeder and JN Sarkaria. (2011). Establishment, maintenance and in vitro and in vivo applications of primary human glioblastoma multiforme (GBM) xenograft models for translational biology studies and drug discovery. Curr Protoc Pharmacol Chapter 14:Unit 14 16.
-
(2011)
Curr Protoc Pharmacol Chapter 14
-
-
Carlson, B.L.1
Pokorny, J.L.2
Schroeder, M.3
Sarkaria, J.N.4
-
28
-
-
54249107246
-
The promise of cancer therapeutics targeting the TNF-related apoptosis-inducing ligand and TRAIL receptor pathway
-
Wang S. (2008). The promise of cancer therapeutics targeting the TNF-related apoptosis-inducing ligand and TRAIL receptor pathway. Oncogene 27:6207-6215.
-
(2008)
Oncogene
, vol.27
, pp. 6207-6215
-
-
Wang, S.1
-
29
-
-
60549094866
-
Connexin43 is involved in the effect of endothelin-1 on astrocyte proliferation and glucose uptake
-
Herrero-Gonzalez S, JC Valle-Casuso, R Sanchez-Alvarez, C Giaume, JM Medina and A Tabernero. (2009). Connexin43 is involved in the effect of endothelin-1 on astrocyte proliferation and glucose uptake. Glia 57:222-233.
-
(2009)
Glia
, vol.57
, pp. 222-233
-
-
Herrero-Gonzalez, S.1
Valle-Casuso, J.C.2
Sanchez-Alvarez, R.3
Giaume, C.4
Medina, J.M.5
Tabernero, A.6
-
30
-
-
1942470517
-
The effects of connexin phosphorylation on gap junctional communication
-
DOI 10.1016/S1357-2725(03)00264-4, PII S1357272503002644
-
Lampe PD and AF Lau. (2004). The effects of connexin phosphorylation on gap junctional communication. Int J Biochem Cell Biol 36:1171-1186. (Pubitemid 38515659)
-
(2004)
International Journal of Biochemistry and Cell Biology
, vol.36
, Issue.7
, pp. 1171-1186
-
-
Lampe, P.D.1
Lau, A.F.2
-
31
-
-
77956414973
-
Phase i dose-escalation study of recombinant human Apo2L/TRAIL, a dual proapoptotic receptor agonist, in patients with advanced cancer
-
Herbst RS, SG Eckhardt, R Kurzrock, S Ebbinghaus, PJ O'Dwyer, MS Gordon, W Novotny, MA Goldwasser, TM Tohnya, et al. (2010). Phase I dose-escalation study of recombinant human Apo2L/TRAIL, a dual proapoptotic receptor agonist, in patients with advanced cancer. J Clin Oncol 28:2839-2846.
-
(2010)
J Clin Oncol
, vol.28
, pp. 2839-2846
-
-
Herbst, R.S.1
Eckhardt, S.G.2
Kurzrock, R.3
Ebbinghaus, S.4
O'Dwyer, P.J.5
Gordon, M.S.6
Novotny, W.7
Goldwasser, M.8
Tohnya, T.M.9
-
32
-
-
0037040922
-
Transduction of cell survival signals by connexin-43 hemichannels
-
DOI 10.1074/jbc.M108625200
-
Plotkin LI, SC Manolagas and T Bellido. (2002). Transduction of cell survival signals by connexin-43 hemichannels. J Biol Chem 277:8648-8657. (Pubitemid 34968331)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.10
, pp. 8648-8657
-
-
Plotkin, L.I.1
Manolagas, S.C.2
Bellido, T.3
-
33
-
-
28944441155
-
Defective gap junctional intercellular communication in the carcinogenic process
-
DOI 10.1016/j.bbamem.2005.11.004, PII S0005273605003615, The Connexins Part III
-
Mesnil M, S Crespin, JL Avanzo and ML Zaidan-Dagli. (2005). Defective gap junctional intercellular communication in the carcinogenic process. Biochim Biophys Acta 1719:125-145. (Pubitemid 41785641)
-
(2005)
Biochimica et Biophysica Acta - Biomembranes
, vol.1719
, Issue.1-2
, pp. 125-145
-
-
Mesnil, M.1
Crespin, S.2
Avanzo, J.-L.3
Zaidan-Dagli, M.-L.4
-
34
-
-
80052038508
-
Gap junctions in human glioblastomas: Implications for suicide gene therapy
-
Cottin S, PV Gould, L Cantin and M Caruso. (2011). Gap junctions in human glioblastomas: implications for suicide gene therapy. Cancer Gene Ther 18:674-681.
-
(2011)
Cancer Gene Ther
, vol.18
, pp. 674-681
-
-
Cottin, S.1
Gould, P.V.2
Cantin, L.3
Caruso, M.4
-
35
-
-
56049092037
-
Bystander effect in glioblastoma cells with a predominant cytoplasmic localization of connexin43
-
Cottin S, K Ghani and M Caruso. (2008). Bystander effect in glioblastoma cells with a predominant cytoplasmic localization of connexin43. Cancer Gene Ther 15:823-831.
-
(2008)
Cancer Gene Ther
, vol.15
, pp. 823-831
-
-
Cottin, S.1
Ghani, K.2
Caruso, M.3
-
36
-
-
21744434924
-
Connexin 43 in cardiomyocyte mitochondria and its increase by ischemic preconditioning
-
DOI 10.1016/j.cardiores.2005.04.014, PII S0008636305001896
-
Boengler K, G Dodoni, A Rodriguez-Sinovas, A Cabestrero, M Ruiz-Meana, P Gres, I Konietzka, C Lopez-Iglesias, D Garcia-Dorado, et al. (2005). Connexin 43 in cardiomyocyte mitochondria and its increase by ischemic preconditioning. Cardiovasc Res 67:234-244. (Pubitemid 40943616)
-
(2005)
Cardiovascular Research
, vol.67
, Issue.2
, pp. 234-244
-
-
Boengler, K.1
Dodoni, G.2
Rodriguez-Sinovas, A.3
Cabestrero, A.4
Ruiz-Meana, M.5
Gres, P.6
Konietzka, I.7
Lopez-Iglesias, C.8
Garcia-Dorado, D.9
Di Lisa, F.10
Heusch, G.11
Schulz, R.12
-
37
-
-
33746207800
-
Translocation of connexin 43 to the inner mitochondrial membrane of cardiomyocytes through the heat shock protein 90-dependent TOM pathway and its importance for cardioprotection
-
DOI 10.1161/01.RES.0000230315.56904.de, PII 0000301220060707000015
-
Rodriguez-Sinovas A, K Boengler, A Cabestrero, P Gres, M Morente, M Ruiz-Meana, I Konietzka, E Miro, A Totzeck, et al. (2006). Translocation of connexin 43 to the inner mitochondrial membrane of cardiomyocytes through the heat shock protein 90-dependent TOM pathway and its importance for cardioprotection. Circ Res 99:93-101. (Pubitemid 44297060)
-
(2006)
Circulation Research
, vol.99
, Issue.1
, pp. 93-101
-
-
Rodriguez-Sinovas, A.1
Boengler, K.2
Cabestrero, A.3
Gres, P.4
Morente, M.5
Ruiz-Meana, M.6
Konietzka, I.7
Miro, E.8
Totzeck, A.9
Heusch, G.10
Schulz, R.11
Garcia-Dorado, D.12
-
38
-
-
38849201088
-
Mitochondrial connexin43 as a new player in the pathophysiology of myocardial ischaemia-reperfusion injury
-
DOI 10.1093/cvr/cvm062
-
Ruiz-Meana M, A Rodriguez-Sinovas, A Cabestrero, K Boengler, G Heusch and D Garcia-Dorado. (2008). Mitochondrial connexin43 as a new player in the pathophysiology of myocardial ischaemia-reperfusion injury. Cardiovasc Res 77:325-333. (Pubitemid 351197646)
-
(2008)
Cardiovascular Research
, vol.77
, Issue.2
, pp. 325-333
-
-
Ruiz-Meana, M.1
Rodriguez-Sinovas, A.2
Cabestrero, A.3
Boengler, K.4
Heusch, G.5
Garcia-Dorado, D.6
-
39
-
-
80054915955
-
Inhibition of gap junction transfer sensitizes thyroid cancer cells to anoikis
-
Jensen K, A Patel, J Klubo-Gwiezdzinska, A Bauer and V Vasko. (2011). Inhibition of gap junction transfer sensitizes thyroid cancer cells to anoikis. Endocr RelatCancer 18:613-626.
-
(2011)
Endocr RelatCancer
, vol.18
, pp. 613-626
-
-
Jensen, K.1
Patel, A.2
Klubo-Gwiezdzinska, J.3
Bauer, A.4
Vasko, V.5
-
40
-
-
36749049766
-
Modulation of osteoblast gap junction connectivity by serum, TNFα, and TRAIL
-
DOI 10.1016/j.yexcr.2007.10.010, PII S0014482707004727
-
Sharrow AC, Y Li, A Micsenyi, RD Griswold, A Wells, SS Monga and HC Blair. (2008). Modulation of osteoblast gap junction connectivity by serum, TNFalpha, and TRAIL. Exp Cell Res 314:297-308. (Pubitemid 350216101)
-
(2008)
Experimental Cell Research
, vol.314
, Issue.2
, pp. 297-308
-
-
Sharrow, A.C.1
Li, Y.2
Micsenyi, A.3
Griswold, R.D.4
Wells, A.5
Monga, S.S.P.6
Blair, H.C.7
-
41
-
-
18244400450
-
Inhibition of Gap junction-mediated intercellular communication by TNF-α in cultured human corneal fibroblasts
-
DOI 10.1167/iovs.04-0840
-
Hao JL, K Suzuki, Y Lu, S Hirano, K Fukuda, N Kumagai, K Kimura and T Nishida. (2005). Inhibition of gap junctionmediated intercellular communication by TNF-alpha in cultured human corneal fibroblasts. Invest Ophthalmol Vis Sci 46:1195-1200. (Pubitemid 41685853)
-
(2005)
Investigative Ophthalmology and Visual Science
, vol.46
, Issue.4
, pp. 1195-1200
-
-
Hao, J.-L.1
Suzuki, K.2
Lu, Y.3
Hirano, S.4
Fukuda, K.5
Kumagai, N.6
Kimura, K.7
Nishida, T.8
-
42
-
-
33845628659
-
Changes in gap junction organization and decreased coupling during induced apoptosis in lens epithelial and NIH-3T3 cells
-
DOI 10.1016/j.yexcr.2006.09.029, PII S001448270600396X
-
Theiss C, A Mazur, K Meller and HG Mannherz. (2007). Changes in gap junction organization and decreased coupling during induced apoptosis in lens epithelial and NIH-3T3 cells. Exp Cell Res 313:38-52. (Pubitemid 44958452)
-
(2007)
Experimental Cell Research
, vol.313
, Issue.1
, pp. 38-52
-
-
Theiss, C.1
Mazur, A.2
Meller, K.3
Mannherz, H.G.4
-
43
-
-
34347249935
-
Gap-junction blocker carbenoxolone differentially enhances NMDA-induced cell death in hippocampal neurons and astrocytes in co-culture
-
DOI 10.1111/j.1471-4159.2007.04509.x
-
Zundorf G, S Kahlert and G Reiser. (2007). Gap-junction blocker carbenoxolone differentially enhances NMDA-induced cell death in hippocampal neurons and astrocytes in co-culture. J Neurochem 102:508-521. (Pubitemid 47000594)
-
(2007)
Journal of Neurochemistry
, vol.102
, Issue.2
, pp. 508-521
-
-
Zundorf, G.1
Kahlert, S.2
Reiser, G.3
-
44
-
-
62449196599
-
LY303511 enhances TRAIL sensitivity of SHEP-1 neuroblastoma cells via hydrogen peroxide-mediated mitogen-activated protein kinase activation and up-regulation of death receptors
-
Shenoy K, Y Wu and S Pervaiz. (2009). LY303511 enhances TRAIL sensitivity of SHEP-1 neuroblastoma cells via hydrogen peroxide-mediated mitogen-activated protein kinase activation and up-regulation of death receptors. Cancer Res 69:1941-1950.
-
(2009)
Cancer Res
, vol.69
, pp. 1941-1950
-
-
Shenoy, K.1
Wu, Y.2
Pervaiz, S.3
-
45
-
-
69249083578
-
Zerumbone enhances TRAIL-induced apoptosis through the induction of death receptors in human colon cancer cells: Evidence for an essential role of reactive oxygen species
-
Yodkeeree S, B Sung, P Limtrakul and BB Aggarwal. (2009). Zerumbone enhances TRAIL-induced apoptosis through the induction of death receptors in human colon cancer cells: evidence for an essential role of reactive oxygen species. Cancer Res 69:6581-6589.
-
(2009)
Cancer Res
, vol.69
, pp. 6581-6589
-
-
Yodkeeree, S.1
Sung, B.2
Limtrakul, P.3
Aggarwal, B.B.4
-
46
-
-
77950796660
-
Garcinol potentiates TRAIL-induced apoptosis through modulation of death receptors and antiapoptotic proteins
-
Prasad S, J Ravindran, B Sung, MK Pandey and BB Aggarwal. (2010). Garcinol potentiates TRAIL-induced apoptosis through modulation of death receptors and antiapoptotic proteins. Mol Cancer Ther 9:856-868.
-
(2010)
Mol Cancer Ther
, vol.9
, pp. 856-868
-
-
Prasad, S.1
Ravindran, J.2
Sung, B.3
Pandey, M.K.4
Aggarwal, B.B.5
-
47
-
-
0038164938
-
Mutations in the second extracellular region of connexin 43 prevent localization to the plasma membrane, but do not affect its ability to suppress cell growth
-
Olbina G and W Eckhart. (2003). Mutations in the second extracellular region of connexin 43 prevent localization to the plasma membrane, but do not affect its ability to suppress cell growth. Mol Cancer Res 1:690-700. (Pubitemid 36870522)
-
(2003)
Molecular Cancer Research
, vol.1
, Issue.9
, pp. 690-700
-
-
Olbina, G.1
Eckhart, W.2
-
48
-
-
77958473896
-
Connexin43 inhibits the oncogenic activity of c-Src in C6 glioma cells
-
Herrero-Gonzalez S, E Gangoso, C Giaume, CC Naus, JM Medina and A Tabernero. (2010). Connexin43 inhibits the oncogenic activity of c-Src in C6 glioma cells. Oncogene 29:5712-5723.
-
(2010)
Oncogene
, vol.29
, pp. 5712-5723
-
-
Herrero-Gonzalez, S.1
Gangoso, E.2
Giaume, C.3
Naus, C.C.4
Medina, J.M.5
Tabernero, A.6
-
49
-
-
34548431646
-
Connexin 43 confers resistance to hydrogen peroxide-mediated apoptosis
-
DOI 10.1016/j.bbrc.2007.08.066, PII S0006291X07017664
-
Giardina SF, M Mikami, F Goubaeva and J Yang. (2007). Connexin 43 confers resistance to hydrogen peroxide-mediated apoptosis. Biochem Biophys Res Commun 362:747-752. (Pubitemid 47368157)
-
(2007)
Biochemical and Biophysical Research Communications
, vol.362
, Issue.3
, pp. 747-752
-
-
Giardina, S.F.1
Mikami, M.2
Goubaeva, F.3
Yang, J.4
-
50
-
-
84870179112
-
Inhibition of connexin 26/43 and extracellularregulated kinase protein plays a critical role in melatonin facilitated gap junctional intercellular communication in hydrogen peroxide-treated HaCaT keratinocyte cells
-
Lee HJ, HJ Lee, EJ Sohn, EO Lee, JH Kim, MH Lee and SH Kim. (2012). Inhibition of connexin 26/43 and extracellularregulated kinase protein plays a critical role in melatonin facilitated gap junctional intercellular communication in hydrogen peroxide-treated HaCaT keratinocyte cells. Evid Based Complement Alternat Med 2012:589365.
-
(2012)
Evid Based Complement Alternat Med
, vol.2012
, pp. 589365
-
-
Lee, H.J.1
Lee, H.J.2
Sohn, E.J.3
Lee, E.O.4
Kim, J.H.5
Lee, M.H.6
Kim, S.H.7
-
51
-
-
84873412992
-
Nutlin-3, a small-molecule MDM2 inhibitor, sensitizes Caki cells to TRAIL-induced apoptosis through p53-mediated PUMA upregulation and ROS-mediated DR5 upregulation
-
Park EJ, KS Choi, YH Yoo and TK Kwon. (2012). Nutlin-3, a small-molecule MDM2 inhibitor, sensitizes Caki cells to TRAIL-induced apoptosis through p53-mediated PUMA upregulation and ROS-mediated DR5 upregulation. Anticancer Drugs 24:260-269.
-
(2012)
Anticancer Drugs
, vol.24
, pp. 260-269
-
-
Park, E.J.1
Choi, K.S.2
Yoo, Y.H.3
Kwon, T.K.4
-
52
-
-
38949112841
-
Apoptosis of dendritic cells induced by decoy receptor 3 (DcR3)
-
You RI, YC Chang, PM Chen, WS Wang, TL Hsu, CY Yang, CT Lee and SL Hsieh. (2008). Apoptosis of dendritic cells induced by decoy receptor 3 (DcR3). Blood 111:1480-1488.
-
(2008)
Blood
, vol.111
, pp. 1480-1488
-
-
You, R.I.1
Chang, Y.C.2
Chen, P.M.3
Wang, W.S.4
Hsu, T.L.5
Yang, C.Y.6
Lee, C.T.7
Hsieh, S.L.8
-
53
-
-
77958553942
-
Hybrid herpes simplex virus/Epstein-Barr virus amplicon viral vectors confer enhanced transgene expression in primary human tumors and human bone marrow-derived mesenchymal stem cells
-
Sia KC, WK Chong, IA Ho, Y Yulyana, B Endaya, H Huynh and PY Lam. (2010). Hybrid herpes simplex virus/Epstein-Barr virus amplicon viral vectors confer enhanced transgene expression in primary human tumors and human bone marrow-derived mesenchymal stem cells. J Gene Med 12:848-858.
-
(2010)
J Gene Med
, vol.12
, pp. 848-858
-
-
Sia, K.C.1
Chong, W.K.2
Ho, I.A.3
Yulyana, Y.4
Endaya, B.5
Huynh, H.6
Lam, P.Y.7
-
54
-
-
32044465504
-
Carbenoxolone does not cross the blood brain barrier: An HPLC study
-
Leshchenko Y, S Likhodii, W Yue, WM Burnham and JL Perez Velazquez. (2006). Carbenoxolone does not cross the blood brain barrier: an HPLC study. BMC Neurosci 7:3.
-
(2006)
BMC Neurosci
, vol.7
, pp. 3
-
-
Leshchenko, Y.1
Likhodii, S.2
Yue, W.3
Burnham, W.M.4
Perez Velazquez, J.L.5
-
55
-
-
0034812659
-
Preclinical studies to predict the disposition of Apo2L/tumor necrosis factor-related apoptosis-inducing ligand in humans: Characterization of in vivo efficacy, pharmacokinetics, and safety
-
Kelley SK, LA Harris, D Xie, L Deforge, K Totpal, J Bussiere and JA Fox. (2001). Preclinical studies to predict the disposition of Apo2L/tumor necrosis factor-related apoptosisinducing ligand in humans: characterization of in vivo efficacy, pharmacokinetics, and safety. J Pharmacol Exp Ther 299:31-38. (Pubitemid 32905115)
-
(2001)
Journal of Pharmacology and Experimental Therapeutics
, vol.299
, Issue.1
, pp. 31-38
-
-
Kelley, S.K.1
Harris, L.A.2
Xie, D.3
Deforge, L.4
Totpal, K.5
Bussiere, J.6
Fox, J.A.7
-
56
-
-
67649307124
-
Engineering a leucine zipper-TRAIL homotrimer with improved cytotoxicity in tumor cells
-
Rozanov DV, AY Savinov, VS Golubkov, OL Rozanova, TI Postnova, EA Sergienko, S Vasile, AE Aleshin, MF Rega, M Pellecchia and AY Strongin. (2009). Engineering a leucine zipper-TRAIL homotrimer with improved cytotoxicity in tumor cells. Mol Cancer Ther 8:1515-1525.
-
(2009)
Mol Cancer Ther
, vol.8
, pp. 1515-1525
-
-
Rozanov, D.V.1
Savinov, A.Y.2
Golubkov, V.S.3
Rozanova, O.L.4
Postnova, T.I.5
Sergienko, E.A.6
Vasile, S.7
Aleshin, A.E.8
Rega, M.F.9
Pellecchia, M.10
Strongin, A.Y.11
-
57
-
-
65349121788
-
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial
-
Stupp R, ME Hegi, WP Mason, MJ van den Bent, MJ Taphoorn, RC Janzer, SK Ludwin, A Allgeier, B Fisher, et al. (2009). Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial. Lancet Oncol 10:459-466.
-
(2009)
Lancet Oncol
, vol.10
, pp. 459-466
-
-
Stupp, R.1
Hegi, M.E.2
Mason, W.P.3
Bent Den M.Van4
Taphoorn, M.J.5
Janzer, R.C.6
Ludwin, S.K.7
Allgeier, A.8
Fisher, B.9
|