Disruption of nodal architecture in skin biopsies of patients with demyelinating neuropathies

Journal of the Peripheral Nervous System

Volumn 18, Issue 2, 2013, Pages 168-176

  Doppler, Kathrin ^a   Werner, Christian ^a   Sommer, Claudia ^a  

^a UNIVERSITY OF WÜRZBURG   (Germany)

Author keywords

demyelination; node of Ranvier; peripheral neuropathy; skin biopsy

Indexed keywords

CONTACTIN;

ADULT; AGED; ARTICLE; CONTROLLED STUDY; DEMYELINATING NEUROPATHY; FEMALE; HUMAN; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; MALE; MYELINATED NERVE; PERIPHERAL NEUROPATHY; PRIORITY JOURNAL; PROSPECTIVE STUDY; SKIN BIOPSY; STAINING;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; BIOPSY; DEMYELINATING DISEASES; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MICROSCOPY, FLUORESCENCE; MIDDLE AGED; PERIPHERAL NERVOUS SYSTEM DISEASES; RANVIER'S NODES; SKIN; YOUNG ADULT;

EID: 84879383920     PISSN: 10859489     EISSN: 15298027     Source Type: Journal    
DOI: 10.1111/jns5.12023     Document Type: Article

References (29)

1. Arroyo EJ, Scherer SS, (2000). On the molecular architecture of myelinated fibers. Histochem Cell Biol 113: 1-18.
2. Arroyo EJ, Sirkowski EE, Chitale R, Scherer SS, (2004). Acute demyelination disrupts the molecular organization of peripheral nervous system nodes. J Comp Neurol 479: 424-434.
3. Black JA, Friedman B, Waxman SG, Elmer LW, Angelides KJ, (1989). Immuno-ultrastructural localization of sodium channels at nodes of Ranvier and perinodal astrocytes in rat optic nerve. Proc R Soc Lond B Biol Sci 238: 39-51.
4. Chang BJ, Cho IJ, Brophy PJ, (2000). A study on the immunocytochemical localization of neurofascin in rat sciatic nerve. J Vet Sci 1: 67-71.
5. Cifuentes-Diaz C, Dubourg O, Irinopoulou T, Vigny M, Lachkar S, Decker L, Charnay P, Denisenko N, Maisonobe T, Leger JM, Viala K, Hauw JJ, Girault JA, (2011). Nodes of ranvier and paranodes in chronic acquired neuropathies. PLoS One 6: e14533.
6. Coman I, Aigrot MS, Seilhean D, Reynolds R, Girault JA, Zalc B, Lubetzki C, (2006). Nodal, paranodal and juxtaparanodal axonal proteins during demyelination and remyelination in multiple sclerosis. Brain 129: 3186-3195.
7. Devaux JJ, (2012). Antibodies to gliomedin cause peripheral demyelinating neuropathy and the dismantling of the nodes of Ranvier. Am J Pathol 181: 1402-1413.
8. Devaux JJ, Odaka M, Yuki N, (2012). Nodal proteins are target antigens in Guillain-Barre syndrome. J Peripher Nerv Syst 17: 62-71.
9. Doppler K, Werner C, Henneges C, Sommer C, (2012). Analysis of myelinated fibers in human skin biopsies of patients with neuropathies. J Neurol 259: 1879-1887.
10. Dupree JL, Girault JA, Popko B, (1999). Axo-glial interactions regulate the localization of axonal paranodal proteins. J Cell Biol 147: 1145-1152.
11. Dzhashiashvili Y, Zhang Y, Galinska J, Lam I, Grumet M, Salzer JL, (2007). Nodes of Ranvier and axon initial segments are ankyrin G-dependent domains that assemble by distinct mechanisms. J Cell Biol 177: 857-870.
12. Howell OW, Palser A, Polito A, Melrose S, Zonta B, Scheiermann C, Vora AJ, Brophy PJ, Reynolds R, (2006). Disruption of neurofascin localization reveals early changes preceding demyelination and remyelination in multiple sclerosis. Brain 129: 3173-3185.
13. Hughes R, Bensa S, Willison H, Van den Bergh P, Comi G, Illa I, Nobile-Orazio E, van Doorn P, Dalakas M, Bojar M, Swan A, (2001). Randomized controlled trial of intravenous immunoglobulin versus oral prednisolone in chronic inflammatory demyelinating polyradiculoneuropathy. Ann Neurol 50: 195-201.
14. Li J, Bai Y, Ghandour K, Qin P, Grandis M, Trostinskaia A, Ianakova E, Wu X, Schenone A, Vallat JM, Kupsky WJ, Hatfield J, Shy ME, (2005). Skin biopsies in myelin-related neuropathies: bringing molecular pathology to the bedside. Brain 128: 1168-1177.
15. Lonigro A, Devaux JJ, (2009). Disruption of neurofascin and gliomedin at nodes of Ranvier precedes demyelination in experimental allergic neuritis. Brain 132: 260-273.
16. Mathey EK, Derfuss T, Storch MK, Williams KR, Hales K, Woolley DR, Al-Hayani A, Davies SN, Rasband MN, Olsson T, Moldenhauer A, Velhin S, Hohlfeld R, Meinl E, Linington C, (2007). Neurofascin as a novel target for autoantibody-mediated axonal injury. J Exp Med 204: 2363-2372.
17. Ng JK, Malotka J, Kawakami N, Derfuss T, Khademi M, Olsson T, Linington C, Odaka M, Tackenberg B, Pruss H, Schwab JM, Harms L, Harms H, Sommer C, Rasband MN, Eshed-Eisenbach Y, Peles E, Hohlfeld R, Yuki N, Dornmair K, Meinl E, (2012). Neurofascin as a target for autoantibodies in peripheral neuropathies. Neurology 79: 2241-2248.
18. Nolano M, Provitera V, Crisci C, Stancanelli A, Wendelschafer-Crabb G, Kennedy WR, Santoro L, (2003). Quantification of myelinated endings and mechanoreceptors in human digital skin. Ann Neurol 54: 197-205.
19. Provitera V, Nolano M, Pagano A, Caporaso G, Stancanelli A, Santoro L, (2007). Myelinated nerve endings in human skin. Muscle Nerve 35: 767-775.
20. Pruss H, Schwab JM, Derst C, Gortzen A, Veh RW, (2011). Neurofascin as target of autoantibodies in Guillain-Barre syndrome. Brain 134: e173 author reply e174.
21. Querol L, Nogales-Gadea G, Rojas-Garcia R, Martinez-Hernandez E, Diaz-Manera J, Suarez-Calvet X, Navas M, Araque J, Gallardo E, Isabel I, (2013). Antibodies to contactin-1 in chronic inflammatory demyelinating polyneuropathy. Ann Neurol 73: 370-380.
22. Reilly MM, (2007). Sorting out the inherited neuropathies. Pract Neurol 7: 93-105.
23. Saporta MA, Katona I, Lewis RA, Masse S, Shy ME, Li J, (2009). Shortened internodal length of dermal myelinated nerve fibres in Charcot-Marie-Tooth disease type 1A. Brain 132: 3263-3273.
24. Scherer SS, Arroyo EJ, (2002). Recent progress on the molecular organization of myelinated axons. J Peripher Nerv Syst 7: 1-12.
25. Sherman DL, Tait S, Melrose S, Johnson R, Zonta B, Court FA, Macklin WB, Meek S, Smith AJ, Cottrell DF, Brophy PJ, (2005). Neurofascins are required to establish axonal domains for saltatory conduction. Neuron 48: 737-742.
26. Susuki K, Rasband MN, (2008). Molecular mechanisms of node of Ranvier formation. Curr Opin Cell Biol 20: 616-623.
27. Thaxton C, Pillai AM, Pribisko AL, Dupree JL, Bhat MA, (2011). Nodes of Ranvier act as barriers to restrict invasion of flanking paranodal domains in myelinated axons. Neuron 69: 244-257.
28. Traka M, Goutebroze L, Denisenko N, Bessa M, Nifli A, Havaki S, Iwakura Y, Fukamauchi F, Watanabe K, Soliven B, Girault JA, Karagogeos D, (2003). Association of TAG-1 with Caspr2 is essential for the molecular organization of juxtaparanodal regions of myelinated fibers. J Cell Biol 162: 1161-1172.
29. ÜËceyler N, Kafke W, Riediger N, He L, Necula G, Toyka KV, Sommer C, (2010). Elevated proinflammatory cytokine expression in affected skin in small fiber neuropathy. Neurology 74: 1806-1813.