The branch-site test of positive selection is surprisingly robust but lacks power under synonymous substitution saturation and variation in GC

Molecular Biology and Evolution

Volumn 30, Issue 7, 2013, Pages 1675-1686

  Gharib, Walid H ^a,b   Robinson Rechavi, Marc ^a,b  

^a UNIVERSITY OF LAUSANNE   (Switzerland)

^b SWISS INSTITUTE OF BIOINFORMATICS   (Switzerland)

Author keywords

adaptive evolution; base composition; codon model

Indexed keywords

DNA;

ARTICLE; CODON; CONTROLLED STUDY; DNA BASE COMPOSITION; FALSE NEGATIVE RESULT; FALSE POSITIVE RESULT; GENE SEQUENCE; LABORATORY DIAGNOSIS; MOLECULAR EVOLUTION; POSITIVE SELECTION; SIMULATION;

ADAPTIVE EVOLUTION; BASE COMPOSITION; CODON MODEL;

AMINO ACID SUBSTITUTION; BASE COMPOSITION; CODON; COMPUTER SIMULATION; EVOLUTION, MOLECULAR; MODELS, GENETIC; OPEN READING FRAMES; PHYLOGENY; SELECTION, GENETIC;

EID: 84879338433     PISSN: 07374038     EISSN: 15371719     Source Type: Journal    
DOI: 10.1093/molbev/mst062     Document Type: Article

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