Tracking antigen-specific CD8+ T cells using MHC class i multimers

Methods in Molecular Biology

Volumn 960, Issue , 2013, Pages 309-326

  Alanio, Cécile ^a   Bouvier, Isabelle ^a   Jusforgues Saklani, Hélène ^a   Albert, Matthew L ^a  

^a INSTITUT PASTEUR   (France)

Author keywords

Antigen specific T cells; MHC Class I multimers; T cell receptor

Indexed keywords

CYTOKINE; EPITOPE; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; POLYMER; HLA ANTIGEN CLASS 1;

ADAPTIVE IMMUNITY; ANTIGEN BINDING; ANTIGEN SPECIFICITY; ARTICLE; CD8+ T LYMPHOCYTE; CYTOMETRY; GENE EXPRESSION; HUMAN; MASS SPECTROMETRY; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; ANIMAL; CHEMISTRY; CYTOLOGY; DISSECTION; FLOW CYTOMETRY; IMMUNOLOGY; INTRACELLULAR SPACE; METABOLISM; MOUSE; PROTEIN MULTIMERIZATION; PROTEIN QUATERNARY STRUCTURE;

ANIMALS; CD8-POSITIVE T-LYMPHOCYTES; CYTOKINES; DISSECTION; FLOW CYTOMETRY; HISTOCOMPATIBILITY ANTIGENS CLASS I; HUMANS; INTRACELLULAR SPACE; MICE; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, QUATERNARY;

MLCS; MLOWN;

EID: 84879318843     PISSN: 10643745     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-62703-218-6_23     Document Type: Article

References (31)

1. Arens R, Schoenberger SP (2010) Plasticity in programming of effector and memory CD8 T-cell formation. Immunol Rev 235(1):190-205. doi: 10.1111/j.0105-2896.2010.00899.x
2. Schumacher TNM, Gerlach C, Heijst JW (2010) Mapping the life histories of T cells. Nat Pub Group 10(9):621-631. doi: 10.1038/ nri2822
3. Coulie PG, Karanikas V, Lurquin C, Colau D, Connerotte T, Hanagiri T, Van Pel A, Lucas S, Godelaine D, Lonchay C, Marchand M, Van Baren N, Boon T (2002) Cytolytic T-cell responses of cancer patients vaccinated with a MAGE antigen. Immunol Rev 188:33-42
4. Lamoreaux L, Roederer M, Koup R (2006) Intracellular cytokine optimization and standard operating procedure. Nat Protoc 1(3):1507-1516. doi: 10.1038/nprot.2006.268
5. Sun Y, Iglesias E, Samri A, Kamkamidze G, Decoville T, Carcelain G, Autran B (2003) A systematic comparison of methods to measure HIV-1 specific CD8 T cells. J Immunol Methods 272(1-2):23-34
6. Altman JD, Moss PA, Goulder PJ, Barouch DH, McHeyzer-Williams MG, Bell JI, McMichael AJ, Davis MM (1996) Phenotypic analysis of antigen-specific T lymphocytes. Science 274(5284):94-96
7. Altman JD, Davis MM (2003) MHC-peptide tetramers to visualize antigen-speci fi c T cells. Curr Protoc Immunol Chapter 17:Unit 17.13. 10.1002/0471142735.im1703s53
8. Davis MM, Altman JD, Newell EW (2011) Interrogating the repertoire: broadening the scope of peptide-MHC multimer analysis. Nat Rev Immunol 11(8):551-558. doi: 10.1038/ nri3020
9. Klenerman P, Cerundolo V, Dunbar PR (2002) Tracking T cells with tetramers: new tales from new tools. Nat Rev Immunol 2(4):263-272. doi: 10.1038/nri777
10. Romero P, Valmori D, Pittet MJ, Zippelius A, Rimoldi D, Lévy F, Dutoit V, Ayyoub M, Rubio-Godoy V, Michielin O, Guillaume P, Batard P, Luescher IF, Lejeune F, Liénard D, Rufer N, Dietrich P-Y, Speiser DE, Cerottini J-C (2002) Antigenicity and immunogenicity of Melan-A/MART-1 derived peptides as targets for tumor reactive CTL in human melanoma. Immunol Rev 188:81-96
11. Baitsch L, Baumgaertner P, Devevre E, Raghav SK, Legat A, Barba L, Wieckowski S, Bouzourene H, Deplancke B, Romero P, Rufer N, Speiser DE (2011) Exhaustion of tumorspecific CD8+ T cells in metastases from melanoma patients. J Clin Invest 121(6):2350-2360. doi: 10.1172/JCI46102
12. Kanodia S, Wieder E, Lu S, Talpaz M, Alatrash G, Clise-Dwyer K, Molldrem JJ (2010) PR1- speci fi c T cells are associated with unmaintained cytogenetic remission of chronic myelogenous leukemia after interferon withdrawal. PLoS One 5(7):e11770. doi: 10.1371/ journal.pone.0011770
13. Rosenberg SA, Dudley ME, Restifo NP (2008) Cancer immunotherapy. N Engl J Med 359(10):1072. doi: 10.1056/NEJMc081511
14. Appay V, Douek DC, Price DA (2008) CD8+ T cell efficacy in vaccination and disease. Nat Med 14(6):623-628. doi: 10.1038/nm.f.1774
15. Ma Q, Wang C, Jones D, Quintanilla KE, Li D, Wang Y, Wieder ED, Clise-Dwyer K, Alatrash G, Mj Y, Munsell MF, Lu S, Qazilbash MH, Molldrem JJ (2010) Adoptive transfer of PR1 cytotoxic T lymphocytes associated with reduced leukemia burden in a mouse acute myeloid leukemia xenograft model. Cytotherapy 12(8):1056-1062. doi: 10.3109/ 14653249.2010.506506
16. Wooldridge L, Lissina A, Cole DK, van den Berg HA, Price DA, Sewell AK (2009) Tricks with tetramers: how to get the most from multimeric peptide-MHC. Immunology 126(2):147-164. doi: 10.1111/j.1365-2567.2008.02848.x
17. Bakker AH, Schumacher TNM (2005) MHC multimer technology: current status and future prospects. Curr Opin Immunol 17(4):428-433. doi: 10.1016/j.coi.2005. 06.008
18. Toebes M, Coccoris M, Bins A, Rodenko B, Gomez R, Nieuwkoop NJ, Van De Kasteele W, Rimmelzwaan GF, Haanen JBAG, Ovaa H, Schumacher TNM (2006) Design and use of conditional MHC class I ligands. Nat Med 12(2):246-251. doi: 10.1038/nm1360
19. Hadrup SR, Toebes M, Rodenko B, Bakker AH, Egan DA, Ovaa H, Schumacher TNM(2009) High-throughput T-cell epitope discovery through MHC peptide exchange. Methods Mol Biol 524:383-405. doi: 10.1007/978-1-59745-450-628
20. Newell EW, Klein LO, Yu W, Davis MM (2009) Simultaneous detection of many T-cell specificities using combinatorial tetramer staining. Nat Pub Group 6(7):497-499. doi: 10.1038/nmeth.1344
21. Hadrup SR, Bakker AH, Shu CJ, Andersen RS, van Veluw J, Hombrink P, Castermans E, Thor Straten P, Blank C, Haanen JB, Heemskerk MH, Schumacher TN (2009) Parallel detection of antigen-speci fi c T-cell responses by multidimensional encoding of MHC multimers. Nat Methods 6(7):520-526. doi: 10.1038/nmeth.1345
22. Chattopadhyay PK, Melenhorst JJ, Ladell K, Gostick E, Scheinberg P, Barrett AJ, Wooldridge L, Roederer M, Sewell AK, Price DA (2008) Techniques to improve the direct ex vivo detection of low frequency antigenspeci fi c CD8+ T cells with peptide-major histocompatibility complex class I tetramers. Cytometry A 73(11):1001-1009. doi: 10.1002/cyto.a.20642
23. Alanio C, Lemaitre F, Law HKW, Hasan M, Albert ML (2010) Enumeration of human antigen-specific naive CD8+ T cells reveals conserved precursor frequencies. Blood 115(18):3718-3725. doi: 10.1182/blood- 2009-10-251124
24. Day CL (2003) Ex vivo analysis of human memory CD4 T cells specific for hepatitis C virus using MHC class II tetramers. J Clin Invest 112(6):831-842. doi: 10.1172/ JCI200318509
25. Moon J, Chu H, Pepper M, Mcsorley S, Jameson S, Kedl R, Jenkins M (2007) Naive CD4+ T cell frequency varies for different epitopes and predicts repertoire diversity and response magnitude. Immunity 27(2):203-213. doi: 10.1016/j.immuni.2007.07.007
26. Moon JJ, Chu HH, Hataye J, Pagán AJ, Pepper M, Mclachlan JB, Zell T, Jenkins MK (2009) Tracking epitope-specific T cells. Nat Protoc 4(4):565-581. doi: 10.1038/nprot.2009.9
27. Obar J, Khanna K, Lefrancois L (2008) Endogenous naive CD8+ T cell precursor frequency regulates primary and memory responses to infection. Immunity 28(6):859-869. doi: 10.1016/j.immuni.2008.04.010
28. Legoux F, Debeaupuis E, Echasserieau K, De La Salle H, Saulquin X, Bonneville M (2010) Impact of TCR reactivity and HLA phenotype on naive CD8 T cell frequency in humans. J Immunol 184(12):6731-6738. doi: 10.4049/ jimmunol.1000295
29. Jenkins MK, Chu HH, Mclachlan JB, Moon JJ (2010) On the composition of the preimmune repertoire of T cells specific for peptide-major histocompatibility complex ligands. Annu Rev Immunol 28(1):275-294. doi: 10.1146/ annurev-immunol-030409-101253
30. Pittet MJ, Valmori D, Dunbar PR, Speiser DE, Liénard D, Lejeune F, Fleischhauer K, Cerundolo V, Cerottini JC, Romero P (1999) High frequencies of naive Melan-A/MART-1-speci fi c CD8(+) T cells in a large proportion of human histocompatibility leukocyte antigen (HLA)-A2 individuals. J Exp Med 190(5):705-715
31. Roederer M (2008) How many events is enough' Are you positive' Cytometry 73A(5):384-385. doi: 10.1002/cyto.a.20549