-
1
-
-
84863906869
-
MicroRNAs as therapeutic targets and their potential applications in cancer therapy
-
Cho WC. MicroRNAs as therapeutic targets and their potential applications in cancer therapy. Expert Opin Ther Targets. 2012, 16(8):747-59, http://dx.doi.org/10.1517/14728222.2012.696102.
-
(2012)
Expert Opin Ther Targets
, vol.16
, Issue.8
, pp. 747-759
-
-
Cho, W.C.1
-
2
-
-
77954697226
-
Drosophila microRNAs 263a/b confer robustness during development by protecting nascent sense organs from apoptosis
-
Hilgers V, Bushati N, Cohen SM. Drosophila microRNAs 263a/b confer robustness during development by protecting nascent sense organs from apoptosis. PLoS Biol. 2010;8:e1000396, http://dx.doi.org/10.1371/journal.pbio.1000396.
-
(2010)
PLoS Biol
, vol.8
-
-
Hilgers, V.1
Bushati, N.2
Cohen, S.M.3
-
3
-
-
80755171566
-
Macro-management of microRNAs in cell cycle progression of tumor cells and its implications in anti-cancer therapy
-
Liang LH, He XH. Macro-management of microRNAs in cell cycle progression of tumor cells and its implications in anti-cancer therapy. Acta Pharmacol Sin. 2011;32(11):1311-20, http://dx.doi.org/10.1038/aps.2011.103.
-
(2011)
Acta Pharmacol Sin
, vol.32
, Issue.11
, pp. 1311-1320
-
-
Liang, L.H.1
He, X.H.2
-
4
-
-
70149098981
-
Highly dynamic and sex-specific expression of microRNAs during early ES cell differentiation
-
Ciaudo C, Servant N, Cognat V, Sarazin A, Kieffer E, Viville S, et al. Highly dynamic and sex-specific expression of microRNAs during early ES cell differentiation. PLoS Genet. 2009;5(8):e1000620, http://dx.doi.org/10.1371/journal.pgen.1000620.
-
(2009)
PLoS Genet
, vol.5
, Issue.8
-
-
Ciaudo, C.1
Servant, N.2
Cognat, V.3
Sarazin, A.4
Kieffer, E.5
Viville, S.6
-
5
-
-
84859460629
-
MicroRNA profiling of follicular lymphoma identifies microRNAs related to cell proliferation and tumor response
-
Wang W, Corrigan-Cummins M, Hudson J, Maric I, Simakova O, Neelapu SS, et al. MicroRNA profiling of follicular lymphoma identifies microRNAs related to cell proliferation and tumor response. Haematologica. 2012;97(4)586-94, http://dx.doi.org/10.3324/haematol.2011.048132.
-
(2012)
Haematologica
, vol.97
, Issue.4
, pp. 586-594
-
-
Wang, W.1
Corrigan-Cummins, M.2
Hudson, J.3
Maric, I.4
Simakova, O.5
Neelapu, S.S.6
-
6
-
-
79961239928
-
miR-21 modulates cell apoptosis by targeting multiple genes in renal cell carcinoma
-
Zhang A, Liu Y, Shen Y, Xu Y, Li X. miR-21 modulates cell apoptosis by targeting multiple genes in renal cell carcinoma. Urology. 2011;78(2):474. e13-9, http://dx.doi.org/10.1016/j.urology.2011.03.030.
-
(2011)
Urology
, vol.78
, Issue.2
, pp. 474
-
-
Zhang, A.1
Liu, Y.2
Shen, Y.3
Xu, Y.4
Li, X.5
-
7
-
-
65349102972
-
The decision to enter mitosis: Feedback and redundancy in the mitotic entry network
-
Lindqvist A, Rodriguez-Bravo V, Medema RH. The decision to enter mitosis: feedback and redundancy in the mitotic entry network. J Cell Biol. 2009;185(2):193-202, http://dx.doi.org/10.1083/jcb.200812045.
-
(2009)
J Cell Biol
, vol.185
, Issue.2
, pp. 193-202
-
-
Lindqvist, A.1
Rodriguez-Bravo, V.2
Medema, R.H.3
-
8
-
-
0030148598
-
Cdc2 activation by phosphorylation
-
Yamashita K. Cdc2 activation by phosphorylation. Seikagaku. 1996;68(5):367-71.
-
(1996)
Seikagaku
, vol.68
, Issue.5
, pp. 367-371
-
-
Yamashita, K.1
-
9
-
-
84858405757
-
Chk1 and Wee1 kinases coordinate DNA replication, chromosome condensation, and anaphase entry
-
Fasulo B, Koyama C, Yu KR, Homola EM, Hsieh TS, Campbell SD, et al. Chk1 and Wee1 kinases coordinate DNA replication, chromosome condensation, and anaphase entry. Mol Biol Cell. 2012;23(6):1047-57, http://dx.doi.org/10.1091/mbc.e11,-1,xxx/mbc.e11-10-0832.
-
(2012)
Mol Biol Cell
, vol.23
, Issue.6
, pp. 1047-1057
-
-
Fasulo, B.1
Koyama, C.2
Yu, K.R.3
Homola, E.M.4
Hsieh, T.S.5
Campbell, S.D.6
-
10
-
-
84855908936
-
Safeguarding genome integrity: The checkpoint kinases ATR, CHK1 and WEE1 restrain CDK activity during normal DNA replication
-
Sorensen CS, Syljuasen RG. Safeguarding genome integrity: the checkpoint kinases ATR, CHK1 and WEE1 restrain CDK activity during normal DNA replication. Nucleic Acids Res. 2012;40(2):477-86, http://dx.doi.org/10.1093/nar/gkr697.
-
(2012)
Nucleic Acids Res
, vol.40
, Issue.2
, pp. 477-486
-
-
Sorensen, C.S.1
Syljuasen, R.G.2
-
11
-
-
77956517283
-
In silico analysis of kinase expression identifies WEE1 as a gatekeeper against mitotic catastrophe in glioblastoma
-
Mir SE, De Witt HP, Krawczyk PM, Balaj L, Claes A, Niers JM, et al. In silico analysis of kinase expression identifies WEE1 as a gatekeeper against mitotic catastrophe in glioblastoma. Cancer Cell. 2010;18(3):244-57, http://dx.doi.org/10.1016/j.ccr.2010.08.011.
-
(2010)
Cancer Cell
, vol.18
, Issue.3
, pp. 244-257
-
-
Mir, S.E.1
de Witt, H.P.2
Krawczyk, P.M.3
Balaj, L.4
Claes, A.5
Niers, J.M.6
-
12
-
-
0036202004
-
Wild-type TP53 inhibits G(2)-phase checkpoint abrogation and radiosensitization induced by PD0166285, a WEE1 kinase inhibitor
-
Li J, Wang Y, Sun Y, Lawrence TS. Wild-type TP53 inhibits G(2)-phase checkpoint abrogation and radiosensitization induced by PD0166285, a WEE1 kinase inhibitor. Radiat Res 2002;157:322-330, http://dx.doi.org/10.1667/0033-7587(2002)157[0322:WTTIGP]2.0.CO;2.
-
(2002)
Radiat Res
, vol.157
, pp. 322-330
-
-
Li, J.1
Wang, Y.2
Sun, Y.3
Lawrence, T.S.4
-
13
-
-
84856023806
-
WEE1 inhibition sensitizes basal breast cancer cells to TRAIL-induced apoptosis
-
Garimella SV, Rocca A, Lipkowitz S. WEE1 inhibition sensitizes basal breast cancer cells to TRAIL-induced apoptosis. Mol Cancer Res. 2012;10(1):75-85, http://dx.doi.org/10.1158/1541-7786.MCR-11-0500.
-
(2012)
Mol Cancer Res
, vol.10
, Issue.1
, pp. 75-85
-
-
Garimella, S.V.1
Rocca, A.2
Lipkowitz, S.3
-
14
-
-
47349092050
-
Explorative data analysis of MCL reveals gene expression networks implicated in survival and prognosis supported by explorative CGH analysis
-
Blenk S, Engelmann JC, Pinkert S, Weniger M, Schultz J, Rosenwald A, et al. Explorative data analysis of MCL reveals gene expression networks implicated in survival and prognosis supported by explorative CGH analysis. BMC Cancer. 2008;8:106, http://dx.doi.org/10.1186/1471-2407-8-106.
-
(2008)
BMC Cancer
, vol.8
, pp. 106
-
-
Blenk, S.1
Engelmann, J.C.2
Pinkert, S.3
Weniger, M.4
Schultz, J.5
Rosenwald, A.6
-
15
-
-
0042698478
-
Therapeutic exploitation of checkpoint defects in cancer cells lacking p53 function
-
Dixon H, Norbury CJ. Therapeutic exploitation of checkpoint defects in cancer cells lacking p53 function. Cell Cycle. 2002;1(6):362-8, http://dx.doi.org/10.4161/cc.1.6.257.
-
(2002)
Cell Cycle
, vol.1
, Issue.6
, pp. 362-368
-
-
Dixon, H.1
Norbury, C.J.2
-
16
-
-
78651307694
-
Starbase: A database for exploring microRNA-mRNA interaction maps from Argonaute CLIPSeq and Degradome-Seq data
-
Yang JH, Li JH, Shao P, Zhou H, Chen YQ, Qu LH. Starbase: a database for exploring microRNA-mRNA interaction maps from Argonaute CLIPSeq and Degradome-Seq data. Nucleic Acids Res. 2011;39(Database issue):D202-9, http://dx.doi.org/10.1093/nar/gkq1056.
-
(2011)
Nucleic Acids Res
, vol.39
, Issue.Database issue
-
-
Yang, J.H.1
Li, J.H.2
Shao, P.3
Zhou, H.4
Chen, Y.Q.5
Qu, L.H.6
-
17
-
-
84874775434
-
Suppressed miR-424 expression via upregulation of target gene Chk1 contributes to the progression of cervical cancer
-
Xu J, Li Y, Wang F, Wang X, Cheng B, Ye F, et al. Suppressed miR-424 expression via upregulation of target gene Chk1 contributes to the progression of cervical cancer. Oncogene. 2013;32(8):976-87, http://dx.doi.org/10.1038/onc.2012.121.
-
(2013)
Oncogene
, vol.32
, Issue.8
, pp. 976-987
-
-
Xu, J.1
Li, Y.2
Wang, F.3
Wang, X.4
Cheng, B.5
Ye, F.6
-
18
-
-
80054919770
-
MicroRNA-16 and microRNA-424 regulate cellautonomous angiogenic functions in endothelial cells via targeting vascular endothelial growth factor receptor-2 and fibroblast growth factor receptor-1
-
Chamorro-Jorganes A, Araldi E, Penalva LO, Sandhu D, Fernandez- Hernando C, Suarez Y. MicroRNA-16 and microRNA-424 regulate cellautonomous angiogenic functions in endothelial cells via targeting vascular endothelial growth factor receptor-2 and fibroblast growth factor receptor-1. Arterioscler Thromb Vasc Biol. 2011;31(11):2595-606, http://dx.doi.org/10.1161/ATVBAHA.111.236521.
-
(2011)
Arterioscler Thromb Vasc Biol
, vol.31
, Issue.11
, pp. 2595-2606
-
-
Chamorro-Jorganes, A.1
Araldi, E.2
Penalva, L.O.3
Sandhu, D.4
Fernandez- hernando, C.5
Suarez, Y.6
-
19
-
-
84861947624
-
MiR-424 and miR-155 deregulated expression in cytogenetically normal acute myeloid leukaemia: Correlation with NPM1 and FLT3 mutation status
-
Faraoni I, Laterza S, Ardiri D, Ciardi C, Fazi F, Lo-Coco F. MiR-424 and miR-155 deregulated expression in cytogenetically normal acute myeloid leukaemia: correlation with NPM1 and FLT3 mutation status. J Hematol Oncol. 2012;5:26, http://dx.doi.org/10.1186/1756-8722-5-26.
-
(2012)
J Hematol Oncol
, vol.5
, pp. 26
-
-
Faraoni, I.1
Laterza, S.2
Ardiri, D.3
Ciardi, C.4
Fazi, F.5
Lo-Coco, F.6
-
20
-
-
84872080490
-
A microRNA panel to discriminate carcinomas from high-grade intraepithelial neoplasms in colonoscopy biopsy tissue
-
Wang S, Wang L, Bayaxi N, Li J, Verhaegh W, Janevski A, et al. A microRNA panel to discriminate carcinomas from high-grade intraepithelial neoplasms in colonoscopy biopsy tissue. Gut. 2013;62(2):280-9, http://dx.doi.org/10.1136/gutjnl-2011-301554.
-
(2013)
Gut
, vol.62
, Issue.2
, pp. 280-289
-
-
Wang, S.1
Wang, L.2
Bayaxi, N.3
Li, J.4
Verhaegh, W.5
Janevski, A.6
-
21
-
-
85044710611
-
Transcriptomic regulation and molecular mechanism of polygenic tumor at different stages
-
Li X, Shen S, Wu M, Li X, Xiong W, Lu J, et al. Transcriptomic regulation and molecular mechanism of polygenic tumor at different stages. Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2011;36(7):585-91.
-
(2011)
Zhong Nan Da Xue Xue Bao Yi Xue Ban
, vol.36
, Issue.7
, pp. 585-591
-
-
Li, X.1
Shen, S.2
Wu, M.3
Li, X.4
Xiong, W.5
Lu, J.6
-
22
-
-
57149115765
-
Genome-wide microRNA expression profiling in renal cell carcinoma: Significant down-regulation of miR-141 and miR- 200c
-
Nakada C, Matsuura K, Tsukamoto Y, Tanigawa M, Yoshimoto T, Narimatsu T, et al. Genome-wide microRNA expression profiling in renal cell carcinoma: significant down-regulation of miR-141 and miR- 200c. J Pathol. 2008;216(4):418-27, http://dx.doi.org/10.1002/path.2437.
-
(2008)
J Pathol
, vol.216
, Issue.4
, pp. 418-427
-
-
Nakada, C.1
Matsuura, K.2
Tsukamoto, Y.3
Tanigawa, M.4
Yoshimoto, T.5
Narimatsu, T.6
-
23
-
-
34547130056
-
Prognostic significance of the mitotic index using the mitosis marker anti-phosphohistone H3 in meningiomas
-
Kim YJ, Ketter R, Steudel WI, Feiden W. Prognostic significance of the mitotic index using the mitosis marker anti-phosphohistone H3 in meningiomas. Am J Clin Pathol. 2007;128(1):118-25.
-
(2007)
Am J Clin Pathol
, vol.128
, Issue.1
, pp. 118-125
-
-
Kim, Y.J.1
Ketter, R.2
Steudel, W.I.3
Feiden, W.4
-
24
-
-
33645086927
-
Two mitosis-specific antibodies, MPM-2 and phospho-histone H3 (Ser28), allow rapid and precise determination of mitotic activity
-
Tapia C, Kutzner H, Mentzel T, Savic S, Baumhoer D, Glatz K. Two mitosis-specific antibodies, MPM-2 and phospho-histone H3 (Ser28), allow rapid and precise determination of mitotic activity. Am J Surg Pathol. 2006;30(1):83-9.
-
(2006)
Am J Surg Pathol
, vol.30
, Issue.1
, pp. 83-89
-
-
Tapia, C.1
Kutzner, H.2
Mentzel, T.3
Savic, S.4
Baumhoer, D.5
Glatz, K.6
-
25
-
-
16444379514
-
Hematopoietic cytokines enhance Chk1-dependent G2/M checkpoint activation by etoposide through the Akt/GSK3 pathway to inhibit apoptosis
-
Jin ZH, Kurosu T, Yamaguchi M, Arai A, Miura O. Hematopoietic cytokines enhance Chk1-dependent G2/M checkpoint activation by etoposide through the Akt/GSK3 pathway to inhibit apoptosis. Oncogene. 2005;24(12):1973-81, http://dx.doi.org/10.1038/sj.onc.1208408.
-
(2005)
Oncogene
, vol.24
, Issue.12
, pp. 1973-1981
-
-
Jin, Z.H.1
Kurosu, T.2
Yamaguchi, M.3
Arai, A.4
Miura, O.5
-
26
-
-
70350733554
-
Insufficient amount of Cdc2 and continuous activation of Wee1 B are the cause of meiotic failure in porcine growing oocytes
-
Nishimura T, Shimaoka T, Kano K, Naito K. Insufficient amount of Cdc2 and continuous activation of Wee1 B are the cause of meiotic failure in porcine growing oocytes. J Reprod Dev. 2009;55(5):553-7, http://dx.doi.org/10.1262/jrd.09-072A.
-
(2009)
J Reprod Dev
, vol.55
, Issue.5
, pp. 553-557
-
-
Nishimura, T.1
Shimaoka, T.2
Kano, K.3
Naito, K.4
-
27
-
-
77953726033
-
Targeting the checkpoint kinase WEE1: Selective sensitization of cancer cells to DNA-damaging drugs
-
Indovina P, Giordano A. Targeting the checkpoint kinase WEE1: selective sensitization of cancer cells to DNA-damaging drugs. Cancer Biol Ther. 2010;9(7):523-5.
-
(2010)
Cancer Biol Ther
, vol.9
, Issue.7
, pp. 523-525
-
-
Indovina, P.1
Giordano, A.2
-
28
-
-
84860788476
-
Downregulation of the tumor-suppressor miR-16 via progestin-mediated oncogenic signaling contributes to breast cancer development
-
Rivas MA, Venturutti L, Huang YW, Schillaci R, Huang TH, Elizalde PV. Downregulation of the tumor-suppressor miR-16 via progestin-mediated oncogenic signaling contributes to breast cancer development. Breast Cancer Res. 2012;14(3):R77, http://dx.doi.org/10.1186/bcr3187.
-
(2012)
Breast Cancer Res
, vol.14
, Issue.3
-
-
Rivas, M.A.1
Venturutti, L.2
Huang, Y.W.3
Schillaci, R.4
Huang, T.H.5
Elizalde, P.V.6
-
29
-
-
79960339454
-
WEE1 kinase targeting combined with DNA-damaging cancer therapy catalyzes mitotic catastrophe
-
De Witt HP, Mir SE, Noske D, Van Noorden CJ, Wurdinger T. WEE1 kinase targeting combined with DNA-damaging cancer therapy catalyzes mitotic catastrophe. Clin Cancer Res. 2011. 1;17(13):4200-7.
-
(2011)
Clin Cancer Res
, vol.1-14
, Issue.13
, pp. 4200-4207
-
-
de Witt, H.P.1
Mir, S.E.2
Noske, D.3
van Noorden, C.J.4
Wurdinger, T.5
-
30
-
-
84863799519
-
Combined inhibition of Chk1 and Wee1: In vitro synergistic effect translates to tumor growth inhibition in vivo
-
Carrassa L, Chila R, Lupi M, Ricci F, Celenza C, Mazzoletti M, et al. Combined inhibition of Chk1 and Wee1: in vitro synergistic effect translates to tumor growth inhibition in vivo. Cell Cycle. 2012;11(13):2507-17, http://dx.doi.org/10.4161/cc.20899.
-
(2012)
Cell Cycle
, vol.11
, Issue.13
, pp. 2507-2517
-
-
Carrassa, L.1
Chila, R.2
Lupi, M.3
Ricci, F.4
Celenza, C.5
Mazzoletti, M.6
-
31
-
-
70449807097
-
microRNAs regulate human embryonic stem cell division
-
Qi J, Yu JY, Shcherbata HR, Mathieu J, Wang AJ, Seal S, et al. microRNAs regulate human embryonic stem cell division. Cell Cycle. 2009;8(22):3729-41, http://dx.doi.org/10.4161/cc.8.22.10033.
-
(2009)
Cell Cycle
, vol.8
, Issue.22
, pp. 3729-3741
-
-
Qi, J.1
Yu, J.Y.2
Shcherbata, H.R.3
Mathieu, J.4
Wang, A.J.5
Seal, S.6
-
32
-
-
77951092180
-
Targeting of mRNAs by multiple miRNAs: The next step
-
Peter ME. Targeting of mRNAs by multiple miRNAs: The next step. Oncogene. 2010;29(15):2161-4, http://dx.doi.org/10.1038/onc.2010.59.
-
(2010)
Oncogene
, vol.29
, Issue.15
, pp. 2161-2164
-
-
Peter, M.E.1
-
33
-
-
79955913660
-
Mir-34a and miR-15a/16 are co-regulated in nonsmall cell lung cancer and control cell cycle progression in a synergistic and Rb-dependent manner
-
Bandi N, Vassella E. Mir-34a and miR-15a/16 are co-regulated in nonsmall cell lung cancer and control cell cycle progression in a synergistic and Rb-dependent manner. Mol Cancer. 2011;10:55, http://dx.doi.org/10.1186/1476-4598-10-55.
-
(2011)
Mol Cancer
, vol.10
, pp. 55
-
-
Bandi, N.1
Vassella, E.2
-
34
-
-
77955928100
-
The human cytomegalovirus microRNA miR-UL112 acts synergistically with a cellular microRNA to escape immune elimination
-
Nachmani D, Lankry D, Wolf DG, Mandelboim O. The human cytomegalovirus microRNA miR-UL112 acts synergistically with a cellular microRNA to escape immune elimination. Nat Immunol. 2010;11(9):806-13, http://dx.doi.org/10.1038/ni.1916.
-
(2010)
Nat Immunol
, vol.11
, Issue.9
, pp. 806-813
-
-
Nachmani, D.1
Lankry, D.2
Wolf, D.G.3
Mandelboim, O.4
|