Apoptosis induced by 13-S-hydroxyoctadecadienoic acid in the breast cancer cell lines, MCF-7 and MDA-MB-231

Iranian Journal of Basic Medical Sciences

Volumn 16, Issue 4, 2013, Pages 653-659

  Tavakoli Yaraki, Masoumeh ^a   Karami Tehrani, Fatemeh ^a  

^a TARBIAT MODARES UNIVERSITY   (Iran)

Author keywords

13 S hydroxyoctadecadienoic acid; Apoptosis; MCF 7; MDA MB 231; PPAR

Indexed keywords

13 S HYDROXYOCTADECADIENOIC ACID; FATTY ACID; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR DELTA; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; BREAST CANCER; CANCER CELL CULTURE; CANCER GROWTH; CANCER INHIBITION; CELL CYCLE ARREST; CELL STRAIN MCF 7; CELL STRAIN MDA-MB-231; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; DOWN REGULATION; FLOW CYTOMETRY; HUMAN; HUMAN CELL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION;

EID: 84879301916     PISSN: 20083866     EISSN: 20083874     Source Type: Journal    
DOI: None     Document Type: Article

References (33)

1. Lambrechts S, Decloedt J, Neven P. Breast cancer prevention: Lifestyle changes and chemoprevention. Acta Clin Belg 2011; 66:283-292.
2. Kasibhatla S, Tseng B. Why target apoptosis in cancer treatment? Mol Cancer Ther 2003; 2:573-580.
3. Brash AR. Lipoxygenases: Occurrence, functions, catalysis, and acquisition of substrate. J Biol Chem 1999; 274:23679-23682.
4. Brash AR, Jisaka M, Boeglin WE, Chang MS, Keeney DS, Nanney LB, et al. Investigation of a second 15s-lipoxygenase in humans and its expression in epithelial tissues. Adv Exp Med Biol 1999; 469:83-89.
5. Shureiqi I, Wojno KJ, Poore JA, Reddy RG, Moussalli MJ, Spindler SA, et al. Decreased 13-s-hydroxyoctadecadienoic acid levels and 15-lipoxygenase-1 expression in human colon cancers. Carcinogenesis 1999; 20:1985-1995.
6. Yuan H, Li MY, Ma LT, Hsin MK, Mok TS, Underwood MJ, Chen GG. 15-lipoxygenases and its metabolites 15(s)-hete and 13(s)-hode in the development of non-small cell lung cancer. Thorax 2010; 65:321-326.
7. Nixon JB, Kim KS, Lamb PW, Bottone FG, Eling TE. 15-lipoxygenase-1 has anti-tumorigenic effects in colorectal cancer. Prostaglandins Leukot Essent Fatty Acids 2004; 70:7-15.
8. Xu XC, Shappell SB, Liang Z, Song S, Menter D, Subbarayan V, et al. Reduced 15s-lipoxygenase-2 expression in esophageal cancer specimens and cells and upregulation in vitro by the cyclooxygenase-2 inhibitor, ns398. Neoplasia 2003; 5:121-127.
9. Hennig R, Kehl T, Noor S, Ding XZ, Rao SM, Bergmann F, et al. TE. 15-lipoxygenase-1 production is lost in pancreatic cancer and overexpression of the gene inhibits tumor cell growth. Neoplasia 2007; 9:917-926.
10. Jiang WG, Watkins G, Douglas-Jones A, Mansel RE. Reduction of isoforms of 15-lipoxygenase (15-lox)-1 and 15-lox-2 in human breast cancer. Prostaglandins Leukot Essent Fatty Acids 2006; 74:235-245.
11. Shureiqi I, Chen D, Lee JJ, Yang P, Newman RA, Brenner DE, et al. 15-lox-1: A novel molecular target of nonsteroidal anti-inflammatory drug-induced apoptosis in colorectal cancer cells. J Natl Cancer Inst 2000; 92:1136-1142.
12. Hsi LC, Xi X, Lotan R, Shureiqi I, Lippman SM. The histone deacetylase inhibitor suberoylanilide hydroxamic acid induces apoptosis via induction of 15-lipoxygenase-1 in colorectal cancer cells. Cancer Res 2004; 64:8778-8781.
13. Kumar KA, Arunasree KM, Roy KR, Reddy NP, Aparna A, Reddy GV, Reddanna P. Effects of (15s)-hydroperoxyeicosatetraenoic acid and (15s)-hydroxyeicosatetraenoic acid on the acute-lymphoblastic-leukaemia cell line jurkat: Activation of the fas-mediated death pathway. Biotechnol Appl Biochem 2009; 52:121-133.
14. Shureiqi I, Chen D, Lotan R, Yang P, Newman RA, Fischer SM, et al. 15-lipoxygenase-1 mediates nonsteroidal anti-inflammatory drug-induced apoptosis independently of cyclooxygenase-2 in colon cancer cells. Cancer Res 2000; 60:6846-6850.
15. Shureiqi I, Wu Y, Chen D, Yang XL, Guan B, Morris JS, et al. The critical role of 15-lipoxygenase-1 in colorectal epithelial cell terminal differentiation and tumorigenesis. Cancer Res 2005; 65:11486-11492.
16. Pasqualini ME, Heyd VL, Manzo P, Eynard AR. Association between e-cadherin expression by human colon, bladder and breast cancer cells and the 13-hode:15-hete ratio. A possible role of their metastatic potential. Prostaglandins Leukot Essent Fatty Acids 2003; 68:9-16.
17. Cimen I, Tuncay S, Banerjee S. 15-lipoxygenase-1 expression suppresses the invasive properties of colorectal carcinoma cell lines hct-116 and ht-29. Cancer Sci 2009; 100:2283-2291.
18. Youssef J, Badr M. Peroxisome proliferator-activated receptors and cancer: Challenges and opportunities. Br J Pharmacol 2011;164:68-82.
19. Chawla A, Repa JJ, Evans RM, Mangelsdorf DJ. Nuclear receptors and lipid physiology: Opening the x-files. Science 2001; 294:1866-1870.
20. Foreman JE, Sharma AK, Amin S, Gonzalez FJ, Peters JM. Ligand activation of peroxisome proliferator-activated receptor-beta/ delta (pparbeta/delta) inhibits cell growth in a mouse mammary gland cancer cell line. Cancer Lett 2010; 288:219-225.
21. Zuo X, Wu Y, Morris JS, Stimmel JB, Leesnitzer LM, Fischer SM, et al. Oxidative metabolism of linoleic acid modulates ppar-beta/ delta suppression of ppar-gamma activity. Oncogene 2006; 25:1225-1241.
22. Sigal E, Grunberger D, Highland E, Gross C, Dixon RA, Craik CS. Expression of cloned human reticulocyte 15-lipoxygenase and immunological evidence that 15-lipoxygenases of different cell types are related. J Biol Chem 1990; 265:5113-5120.
23. Mahipal SV, Subhashini J, Reddy MC, Reddy MM, Anilkumar K, Roy KR, et al. Effect of 15-lipoxygenase metabolites, 15-(s)-hpete and 15-(s)-hete on chronic myelogenous leukemia cell line k-562: Reactive oxygen species (ros) mediate caspase-dependent apoptosis. Biochem Pharmacol 2007; 74:202-214.
24. Kim JH, Chang JH, Yoon JH, Lee JG, Bae JH, Kim KS. 15-lipoxygenase-1 induced by interleukin-4 mediates apoptosis in oral cavity cancer cells. Oral Oncol 2006; 42:825-830.
25. Viita H, Pacholska A, Ahmad F, Tietavainen J, Naarala J, Hyvarinen A, et al. 15-lipoxygenase-1 induces lipid peroxidation and apoptosis, and improves survival in rat malignant glioma. In Vivo 2012; 26:1-8.
26. Glinghammar B, Skogsberg J, Hamsten A, Ehrenborg E. Ppardelta activation induces cox-2 gene expression and cell proliferation in human hepatocellular carcinoma cells. Biochem Biophys Res Commun 2003; 308:361-368.
27. Stephen RL, Gustafsson MC, Jarvis M, Tatoud R, Marshall BR, Knight D, et al. Activation of peroxisome proliferator-activated receptor delta stimulates the proliferation of human breast and prostate cancer cell lines. Cancer Res 2004; 64:3162-3170.
28. Yin Y, Russell RG, Dettin LE, Bai R, Wei ZL, Kozikowski AP, et al. Peroxisome proliferator-activated receptor delta and gamma agonists differentially alter tumor differentiation and progression during mammary carcinogenesis. Cancer Res 2005; 65:3950-3957.
29. Ghosh M, Ai Y, Narko K, Wang Z, Peters JM, Hla T. Ppardelta is protumorigenic in a mouse model of cox-2-induced mammary cancer. Prostaglandins Other Lipid Mediat 2009; 88:97-100.
30. Glasgow WC, Hui R, Everhart AL, Jayawickreme SP, AngermanStewart J, Han BB, et al. The linoleic acid metabolite, (13s)-hydroperoxyoctadecadienoic acid, augments the epidermal growth factor receptor signaling pathway by attenuation of receptor dephosphorylation. Differential response in syrian hamster embryo tumor suppressor phenotypes. J Biol Chem 1997; 272:19269-19276.
31. Sauer LA, Dauchy RT, Blask DE, Armstrong BJ, Scalici S. 13-hydroxyoctadecadienoic acid is the mitogenic signal for linoleic acid-dependent growth in rat hepatoma 7288ctc in vivo. Cancer Res 1999; 59:4688-4692.
32. Kelavkar UP, Cohen C, Kamitani H, Eling TE, Badr KF. Concordant induction of 15-lipoxygenase-1 and mutant p53 expression in human prostate adenocarcinoma: Correlation with gleason staging. Carcinogenesis 2000; 21:1777-1787.
33. Kelavkar UP, Nixon JB, Cohen C, Dillehay D, Eling TE, Badr KF. Overexpression of 15-lipoxygenase-1 in pc-3 human prostate cancer cells increases tumorigenesis. Carcinogenesis 2001; 22:1765-1773.